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Patent Searching and Data


Matches 151 - 200 out of 6,220

Document Document Title
WO/2016/049282A1
The invention relates to a compound prepared by (i) reacting (a) at least one compound selected from diisocyanate, polyisocyanate, or mixture thereof; (b) at least one isocyanate-reactive compound selected from a fluorinated alcohol; a c...  
WO/2016/035328A1
Provided are: a dispersant which has excellent solubility in a solvent, excellent adhering power to a colorant and excellent colorant dispersibility, while being reduced in self-coloring; a compound and a polymerizable compound for prepa...  
WO/2016/033635A1
The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in ...  
WO/2016/030329A1
Novel efficient, time-saving and reliable radiofluorination procedures for the production of 18F-labelled active esters via nucleophilic substitution of the corresponding onium precursors with 18F- are described. The active ester includi...  
WO/2016/016178A1
The invention relates to the use of a CXCR2 antagonist for the prevention and/or treatment of chemotherapy induced peripheral neuropathy (CIPN).  
WO/2016/013633A1
A compound represented by formula (I) or a salt thereof has an excellent noxious organism control activity, particularly an excellent miticidal activity and/or an excellent insecticidal activity, is highly safe, and can be synthesized in...  
WO/2016/010432A1
Disclosed is a process for the preparation of a urea product suitable for being diluted with water so as to form an aqueous urea comprising solution for use in a unit for the reduction of NOx in combustion engine exhaust gases, also know...  
WO/2015/188060A1
Fluorosulfonyl-substituted sEH inhibitors are compounds represented by Formula (I): wherein R1 is selected from the group consisting of alkyl, heteroalkyi, C5-C12 cycloalkyi, C5-C12 cycloalkylalkyi, C5-C12 cycloalkylheteroalkyi, arylalky...  
WO/2015/181186A1
The invention relates to 1-(3-sulfonylphenyl)-3-(cyclopent-2-en-1-yl)urea derivatives, and their use in treating or preventing diseases and conditions mediated by the CXCR2 receptor. In addition, the invention relates to compositions con...  
WO/2015/176135A1
The present invention relates to new omega-3 fatty acid analogues and to their use in cancer therapy, including anti-metastatic therapy.  
WO/2015/165352A1
The present invention provides a compound with a structure represented by general formula I or a pharmaceutically acceptable salt thereof, a preparation method for the compound or the salt, and a use of the compound or the pharmaceutical...  
WO/2015/158792A1
The invention relates to rheology control agents comprising at least one active substance of general formula (I) and at least one active substance of general formula RB4OOC-NH-RB3-NH-CO-NRB2-(CH2)x-RB1-(CH2)x-RB2-CO-NH-RB3-NH- COORB4, to...  
WO/2015/158794A1
The invention relates to a urea preparation containing (A) 5 to 75 wt.% of one or more urea components which have a molecular weight of at least 350 g/mol and contain at least one urea group; (B) 15 to 95 wt.%, preferably 30 to 80 wt.%, ...  
WO/2015/136292A1
The invention relates to a DDX3X inhibitorfor use in the treatment of pneumovirus infection in a mammal, wherein the DDX3X inhibitor may be a compound of Formula (I) wherein y, Z, R1, X, L, Ra and Rb are as defined herein. The invention ...  
WO/2015/134839A1
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula (I): or pharmaceutically acceptable...  
WO/2015/126150A1
The present application relates to a t-butyl ketone binaphthol derivative and a method for manufacturing same, the t-butyl ketone binaphthol derivative being a high-efficiency chiral-extracting agent which has very high chiral selectivit...  
WO/2015/109666A1
Disclosed are an ester group-containing aromatic propionamide compound, and a preparation method therefor and uses thereof, and provides a chemical structure formula of the new ester group-containing aromatic propionamide compound. The c...  
WO/2015/019192A3
There are provided pyrrolysine analogues of the formulae (X), (I), (II), (V), (VI), (VII) and (VIII), in which the a, b, d, X, Y, Z, FG, R, R1, R2 and R3 are as defined in the claims, which are useful in bioconjugation processes and muta...  
WO/2015/100252A1
Felbamate deuterated at the 2 position, compositions containing the same, and methods of making and using thereof are described herein. Substitution of the hydrogen at the 2 position with deuterium should prevent or reduce formation of t...  
WO/2015/092807A1
The present invention provides a novel process for preparing Alogliptin free base and its benzoate salt which comprises insitu condensation process to produce protected Alogliptin by reacting 6-chloro-3-methylpyrimidine-2, 4(1H, 3H)-dion...  
WO/2015/089962A1
Provided is a method for continuously preparing biuret polyisocyanate, comprising: a mixed solution of a diisocyanate and a catalyst with water vapour, in an aerosol form, are continuously reacted in a first reactor; the product obtained...  
WO/2015/089271A1
A compound, or a protonate or salt thereof, having a formula I of: wherein Y represents an optionally substituted aromatic group; n is 1 or 2; a is 0 to 4; R1 and R2 are each independently H; optionally substituted alkyl; optionally subs...  
WO/2015/084299A1
Disclosed herein are gemini surfactants, and methods for making and using these gemini surfactants. These gemini surfactants may be incorporated in paints and coatings to provide hydrophilic and/or self-cleaning properties. Coatings and ...  
WO/2015/080665A1
The invention relates to compounds of formula (I) or derivatives, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites or prodrugs thereof, in which ...  
WO/2015/056164A1
The invention relates to a process for the synthesis of Cariprazine, an antipsychotic compound useful in the treatment of positive and negative symptoms associated to schizophrenia, with the following structural formula: (A) The inventio...  
WO/2015/056782A1
The purpose of the present invention is to provide a novel compound having ACC2-inhibiting activity and to provide a pharmaceutical composition comprising said compound. A compound indicated by formula (in the formula, R1 indicates a sub...  
WO/2015/039172A1
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.  
WO/2015/040425A1
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: Y is –CONR1- or optionally substituted arylene or optionally substituted heteroarylene; R1 is H, Cl, F, CH3 or CF3; 10 each R4 is independently H, CH3 or ...  
WO/2015/042071A1
The present invention relates to diphenyl urea derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor 2.  
WO/2015/030085A1
A photosensitive layer comprises: a phthalocyanine crystal in which a urea compound is contained. The urea compound has one or more urea moieties comprising: a carbonyl group, or a thiocarbonyl group, and two nitrogen atoms. Each of the ...  
WO/2015/012407A1
The present invention pertains to a cellulose acylate film containing a compound having at least one linking group selected from the group consisting of a bivalent linking group represented by -NH-(C=O)-O- and a bivalent linking group re...  
WO/2015/009545A1
The present invention relates to derivatives of N-urea substituted amino acids, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide 2 receptor.  
WO/2015/002918A1
There are disclosed compounds of formula (I) that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, suc...  
WO/2014/184248A3
Compounds of Formula (I), pharmaceutically acceptable salts thereof, diastereomers, enantiomers, or mixtures thereof: wherein R1, R2, R3, X, Yn and A are as defined in the specification, as well as pharmaceutical compositions including t...  
WO/2014/207960A1
Provided are a method for effectively removing triuret from aqueous urea, a method for producing high purity aqueous urea, and a method for recovering triuret from aqueous urea. To this end, the method for producing aqueous urea comprise...  
WO/2014/202703A1
The present invention relates to novel strobilurine type compounds I, processes for preparing these compounds, a use of compounds of the formula I and/or their agriculturally useful salts for controlling phytopathogenic fungi, to composi...  
WO/2014/176636A9
The invention provides compounds of Formula (I), and methods of treating or preventing a bacterial infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufactur...  
WO/2014/192823A1
Provided is a urea synthesis method of excellent reliability and productivity, the method minimizing the amount of oxygen used as an anti-corrosion agent without using a special two-phase stainless steel. In the urea synthesis device, wh...  
WO/2014/183221A1
Resveratrol analogs and their use to inhibit Kv1.5 channels are provided. The resveratrol analogs are useful in the treatment of atrial arrhythmias, including atrial fibrillation (AF). Exemplary resveratrol analogs are compounds of gener...  
WO/2014/184116A1
The invention relates to new carbodiimides having terminal urea and/or urethane groups of formula (I), wherein R can be the same or different and is selected from the group of the -NHCONHR', -NHCONR'R'', and -NHCOOR''' residues. The inve...  
WO/2014/184248A2
Compounds of Formula (I), pharmaceutically acceptable salts thereof, diastereomers, enantiomers, or mixtures thereof: wherein R1, R2, R3, X, Yn and A are as defined in the specification, as well as pharmaceutical compositions including t...  
WO/2014/176636A1
The invention provides compounds of Formula (I), and methods of treating or preventing a bacterial infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufactur...  
WO/2014/174745A1
Compared to a traditional Eg5 (KSP: kinesin spindle protein) inhibitor, this water-soluble polycyclic compound or a pharmacologically acceptable salt thereof has a greater solubility in an aqueous solvent and has Eg5 inhibitory activity ...  
WO/2014/158654A1
Compounds of formula (II): wherein A, R1, R2, R5 and R13 are described herein, or a stereoisomer, enantiomer or tautomer thereof or mixtures thereof, or a pharmaceutically acceptable salt or solvate thereof, are described herein, as well...  
WO/2014/150646A1
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, vi...  
WO/2014/146995A1
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, W, A and B are as described herein, compositions including the compounds and methods of using the compounds.  
WO/2014/118556A3
Sphingosine 1-phosphate (S1P) is involved in hyper-proliferative diseases, such as cancer and vascular remodeling in pulmonary arterial hypertension. Inhibitors of sphingosine kinase 1 and 2 (SK1 and SK2), which catalyze the synthesis of...  
WO/2014/140238A1
The invention relates to a modified allophanate compound bearing acrylate functions, resulting from the reaction of a particular allophanate with an ester from the reaction between an acid selected from acrylic acid and methacrylic acid ...  
WO/2014/143561A1
Compounds of formula (I): where R1, R2, R3, R4a, R4b, R5, R6 and R7 are defined herein, or stereoisomers or pharmaceutically acceptable salts thereof, are described herein. Such compounds have activity as SHIP1 modulators, and thus may b...  
WO/2014/111102A3
The present invention relates to a composition that is effective as a rheology additive and contains 15 - 95% by weight of an oxygen compound (A), 5 - 75% by weight of a urea compound (B), 0 - 50% by weight of an ionogenic compound (C) a...  

Matches 151 - 200 out of 6,220