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Patent Searching and Data


Matches 1 - 50 out of 6,214

Document Document Title
WO/2020/183745A1
Provided are a new urea production method and device that enable heat recovery from a fluid at a relatively low temperature. This urea production method includes a synthesis step, a high-pressure decomposition step, and a condensation st...  
WO/2020/156345A1
The present invention relates to the technical field of biomedicine, and specifically relates to a PSMA inhibitor, a compound and an application. The PSMA inhibitor having a novel core structure as provided by the present invention has v...  
WO/2020/150740A1
Prostate-specific membrane antigen (PSMA) targeted compounds having formula (I), nanoclusters formed thereof, pharmaceutical compositions comprising a plurality of these compounds, and methods for treating and detecting cancers in a subj...  
WO/2020/148760A1
The invention generally concerns a novel class of CB 1 receptor binding molecules and uses thereof.  
WO/2020/139012A1
The present invention relates to a 18F-labeled compound for diagnosing prostate cancer and a use thereof. The carboxylic acid-introduced compound of the present invention forms strong ion-pair bonds (salt-bridge interactions) with argini...  
WO/2020/123674A1
The present invention includes substituted arylmethyl ureas and heteroarylmethyl-ureas, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infections in a patient.  
WO/2020/117408A1
Organic isocyanates are converted to ureas by heating in the presence of certain cobalt, magnesium, chromium and lanthanide series organometallic catalysts. The process requires no water or other reactants. The process is particularly us...  
WO/2020/095221A1
The present invention involves obtaining steam and steam condensate having relatively high utility value from low-pressure steam condensate generated when low-pressure steam is consumed in a purification step and/or a concentration step....  
WO/2020/075082A1
The invention relates to a process for the synthesis of carglumic acid from L-glutamic acid and sodium cyanate by treatment with a lithium compound in an aqueous medium. The process according to the invention is easily industrially scala...  
WO/2020/072605A1
The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepa...  
WO/2020/069561A1
The present disclosure provides a composition for treating urea particles under ambient atmospheric conditions, a method for treating urea particles with the composition and to a fertiliser treated with the composition. The composition f...  
WO/2020/061367A1
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions fu...  
WO/2020/022783A9
The present invention pertains to: a novel p62 ligand compound or a stereoisomer, solvate, hydrate, or prodrug thereof; and a pharmaceutical or food composition containing same as an active ingredient for preventing or treating protein a...  
WO/2020/041871A1
This application is directed to the use of a ketogenic agent, such as 1,3-butanediol, R-β-hydroxybutyl-R-β-hydroxybutyrate, or triheptanoin, in the treatment of an individual having a lysosomal storage disease, including Pompe disease....  
WO/2020/043831A1
The present invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof useful as inhibitors of Cyclophilins and modulators of cyclophilin-like proteins. The invention also relates to uses of said compound...  
WO/2020/042559A1
The present invention relates to the technical field of natural substance extracting, and disclosed is a method for synchronously extracting lycopene and citrulline from a watermelon. The method for synchronously extracting lycopene and ...  
WO/2020/042557A1
The present invention relates to the technical field of natural substance extraction. Disclosed is a method for extracting citrulline from a watermelon. The method for extracting citrulline from a watermelon in the present invention comp...  
WO/2020/040049A1
This composition includes a compound (A) represented by general formula (1) and a compound (B) represented by general formula (2), wherein the contained amount of the compound (B) is 0.00002-2.0 parts by mass with respect to 100 parts by...  
WO/2020/033909A1
Disclosed is a composition and method for a therapeutic treatment that is able to combat triple negative breast cancers (TNBCs). The class of urea compounds acts by blocking at inhibiting the mTOR signaling pathway, which, as a central r...  
WO/2020/028515A1
Disclosed herein are small molecule compounds capable of disrupting Kv2.1-syntaxin binding. The compounds are useful for treating a variety of neurological disorders, diseases, and injuries.  
WO/2020/022783A1
The present invention pertains to: a novel p62 ligand compound or a stereoisomer, solvate, hydrate, or prodrug thereof; and a pharmaceutical or food composition containing same as an active ingredient for preventing or treating protein a...  
WO/2020/022784A1
The present invention relates to a novel p62 ligand compound, or a stereoisomer, solvate, hydrate, or prodrug thereof, and a pharmaceutical or food composition for preventing or treating proteopathies comprising same as an active ingredi...  
WO/2020/021998A1
Provided are a method and device for manufacturing urea, whereby heating in a step for preheating or medium-pressure decomposition of starting material ammonia can be performed at a relatively low pressure while avoiding a decrease in th...  
WO/2020/012339A1
The invention is directed to substituted carbon-linked bicycloalkane derivatives. Specifically, the invention is directed to compounds according to Formula (X): (X) wherein C', D', L2', L3', R1', R2', R3', R4', R5', R6', R7', R8', z1', z...  
WO/2020/009016A1
The present invention provides a method for producing an organic compound in which functional groups are reacted with each other without the use of a solvent. The present invention pertains to a method for producing an organic compound c...  
WO/2020/010244A1
The present disclosure provides compounds for the inhibition of soluble epoxide hydrolase and associate disease conditions, as well as a method of treating or preventing disorders in a subject by inhibition of soluble epoxide hydrolase.  
WO/2020/006177A1
Disclosed herein are small molecule Vascular Adhesion Protein- 1 (VAP-1) modulator compositions, pharmaceutical compositions, the use and preparation thereof.  
WO/2019/243414A1
The present invention relates to soluble epoxide hydrolase (sEH) inhibitors of formula (I) to processes for their obtention and to their therapeutic indications.  
WO/2019/229464A1
There are described compounds of formula (I): (I) and their use as a medicament in the treatment of diseases associated with the abnormal or elevated catabolism of tryptophan, such as, cancer, immunosuppression, viral infection, depressi...  
WO/2019/222834A1
This application pertains to group 5 metal complexes having the structure of Formula I: and their potential utility in catalyzing amination of polyolefins having alkene groups.amine-  
WO/2019/221192A1
The present invention provides a method for producing an amino acid aminoalkyl ester or an inorganic acid salt thereof by reacting a compound represented by general formula (I) or a compound represented by general formula (III), or a sal...  
WO/2019/217509A1
The present invention relates to the field of anti-cancer compounds. More particularly, the invention relates to a family of benzothiazolyi urea or thiorurea compound useful as such agents. The present invention also relates to methods f...  
WO/2019/175799A3
The present invention relates to method of modulating TIGIT signaling pathway and PD-1 signaling pathway. The invention also encompasses the use of the compound of formula (I) or a stereoisomer thereof or a pharmaceutically acceptable sa...  
WO/2019/198592A1
A compound represented by formula (I) or a salt thereof. In formula (I), R1 represents a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group or the like; R2 represents a hydrogen atom or a C1-6 alkyl group; each of R3 and R4 i...  
WO/2019/198600A1
[Problem] To provide a method for producing urea that curbs corrosion of a urea plant and increases the reaction yield. [Solution] A method for producing urea from raw production materials including NH3 and CO2 at a urea production plant...  
WO/2019/195634A1
Compounds are provided having the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein A, B, L, R3, R4, R5, R6, R8, m and n are as defined herein. Such compounds...  
WO/2019/178248A1
Disclosed herein, inter alia, are inhibitors of integrin alpha 2 beta 1 and methods of using the same.  
WO/2019/164442A1
Use of a non-ionic deep eutectic mixture consisting of A and B, A being R1R2N-CO-NR3R4 and B being selected from the group consisting of R5R6N-CO-CH3 and R7R8N-CO-NR9R10, and wherein each of R1-R10 is independently H, CH3 or alkyl, as a ...  
WO/2019/160037A1
The purpose of the present invention is to provide methods for producing a carboxamide compound, a sulfonamide compound, and an ester compound using an acid halide. The methods for producing a carboxamide compound, a sulfonamide compound...  
WO/2019/151384A1
One embodiment of the present invention relates to novel substances, etc., which are: [1] a compound, etc., represented by formula (A1) or formula (B1); [2] a compound, etc., represented by formula (A2) or formula (B2); [3] a compound, e...  
WO/2019/137724A1
The present invention relates to ureylene additives, a method for their preparation, a use of said ureylene additives favorably as additive in metal or metal alloy deposition composition, preferably in a copper or copper alloy deposition...  
WO/2019/124411A1
A medicinal composition for preventing or treating secondary hyperparathyroidism under maintenance dialysis, said medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carmaboylamino}-5-chloro-4-m ethylbenzenesulfonic acid or ...  
WO/2019/107322A1
A monomer which can yield a cured product having both high toughness and rigidity, a monomer composition containing said monomer, said monomer composition used as a dental material monomer composition, a dental material composition conta...  
WO/2019/106784A1
The present invention is provided with a reformer 1 for reforming a hydrocarbon source to obtain hydrogen and carbon dioxide, an ammonia production unit 10 for using the hydrogen and carbon dioxide obtained by the reformer 1 to obtain am...  
WO/2019/106490A1
The present invention is directed towards a process for the preparation of Cariprazine (Ia) or a pharmaceutically acceptable salt thereof, wherein, N,N- dimethyl-1H-imidazole-1-carboxamide alkyl halide (VII) is reacted with trans-4- (2-(...  
WO/2019/092253A1
The present invention relates to an improved process of preparation of idelalisib using a solid form of intermediate of formula (2); characterized by XRPD pattern having 20 values 5.5°, 10.9°, 14.3°, 16.9° (±0.2) the process compris...  
WO/2019/074822A1
The present invention provides compounds of formula (I), formula (II) or formula (III), wherein all of the variables are as defined herein. These compounds are inhibitors of indoleamine 2,3-dioxygenase (IDO), which may be used as medicam...  
WO/2019/051222A1
The present disclosure provides a benzene fused heterocyclic derivative of Formula (I): --̅-̅-̅ is a single or double bond; n is an integer of 0 or 1; A is -CH2-, -CH(OH)-, or - C(O)-; G is C or N; X is -CH2-, O, or -C(O)-; Y is alkyl...  
WO/2019/046931A1
Compounds of general formula IA, IB and IC outlined below, including pharmaceutically acceptable salts, solvates and hydrates thereof. Such compounds and pharmaceutical compositions comprising them may be used in medical conditions invol...  
WO/2019/040109A1
Provided are processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate, or a salt, solvate, hydrate, enantiomer, mixture of enantiomers, or isotopologue thereof. Also provided are solid forms of various intermediates an...  

Matches 1 - 50 out of 6,214