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Matches 1 - 50 out of 1,286

Document Document Title
WO/2017/214680A1
The present invention relates to new multi-functional compounds that are useful in the treatment of neurodegenerative diseases, such as Alzheimer's disease, to the preparation of the compounds, and to compositions including the compounds...  
WO/2017/133675A1
The present invention relates to a method for preparing a high-purity cyclohexenone long-chain alcohol represented by formula I. The compound represented by formula I is prepared by using metal-mediated Barbier reaction. The method of th...  
WO/2017/100602A1
Disclosed herein are methods of preparing an aminimide. An epoxy compound is reacted with a hydrazine compound comprising a trivalent nitrogen, and an anhydride functional material or a cyclic compound containing a carbonyl group and at ...  
WO/2017/053776A1
Glucosepane is a structurally complex protein post-translational modification (PTM) believed to exist in all living organisms. Research in humans suggests that glucosepane plays a critical role in the pathophysiology of both diabetes and...  
WO/2016/171038A1
This gas-generating agent comprises a compound represented by the following general formula (1).  
WO/2016/162688A1
The present invention discloses a method to discover selective inhibitors of phosphatases. Thus the invention provides a method for screening a test compound to determine whether the compound binds a holophosphatase selectively or non-se...  
WO/2016/162689A1
The present invention relates to inhibitors of PPP1 R15A and PPP1 R15B and their use in therapy, particularly in the treatment of a disease state alleviated by the inhibition of PPP1 R15A and PPP1 R15B, for example a disorder associated ...  
WO/2016/131201A1
Isopropoxy-benzoguanamine series salt as shown by the formula (I) and an application thereof in preparing a growth promoter for animal feed, wherein R is DL-lactic acid, methanesulfonic acid, 2-isethionic acid, citric acid, tartaric acid...  
WO/2016/108045A2
The invention discloses compounds of the formula wherein A, B, X, Y and Z are defined. The compounds of the invention show activity against a range of bacteria, and are useful in the treatment or prophylaxis of a bacterial infection in a...  
WO/2016/108045A4
The invention discloses compounds of the formula wherein A, B, X, Y and Z are defined. The compounds of the invention show activity against a range of bacteria, and are useful in the treatment or prophylaxis of a bacterial infection in a...  
WO/2016/108045A3
The invention discloses compounds of the formula wherein A, B, X, Y and Z are defined. The compounds of the invention show activity against a range of bacteria, and are useful in the treatment or prophylaxis of a bacterial infection in a...  
WO/2016/039466A1
 Provided is an economical, safe, and more environmentally-friendly production method for azodicarbonamide. According to the present invention, in a homogeneous system or heterogeneous miscible system of water or an organic solvent o...  
WO/2016/039274A1
The present invention provides a compound represented by formula (1) or formula (2). (In formula (1), X is an acid that forms a salt with a guanidine moiety, and the R1 and R2 moieties are each independently at least one type selected fr...  
WO/2016/033635A1
The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in ...  
WO/2016/013033A1
The present invention discloses a novel vinylic 3-amino-1,2 diol compounds of formula (I) and a one pot cost-effective process for the synthesis of vinylic-3-amino-1,2-diols of formula (I) which comprises tandem α-amination-benzoyloxyal...  
WO/2016/013033A4
The present invention discloses a novel vinylic 3-amino-1,2 diol compounds of formula (I) and a one pot cost-effective process for the synthesis of vinylic-3-amino-1,2-diols of formula (I) which comprises tandem α-amination-benzoyloxyal...  
WO/2016/001390A1
The present invention relates to a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof Formula (I), and its uses to treat a disorder associated with protein misfolding stress and in particular with an...  
WO/2015/198343A1
The present invention relates to novel ortho alkynyl anilines of formula (I) which are useful in synthesis of drug intermediates and natural products and process for preparation of these ortho alkynyl anilines of formula (I) via copper c...  
WO/2015/190504A1
 Provided is a compound represented by formula (1). (In the formula, X is an acid that forms a salt with a guanidine region, R1 and R2 are each independently any moiety selected from the group consisting of C1-18 alkyl groups, cycloalk...  
WO/2015/113321A1
A diamino guanidine derivative as represented by formula I, wherein R1 represents methyl, ethyl, isopropyl, n-butyl, n-propyl, n-pentyl, n-octyl, n-tetradecyl, secbutyl, 3-pentyl, cyclopentyl or benzyl. When first using the compound in f...  
WO/2014/202703A1
The present invention relates to novel strobilurine type compounds I, processes for preparing these compounds, a use of compounds of the formula I and/or their agriculturally useful salts for controlling phytopathogenic fungi, to composi...  
WO/2014/176636A1
The invention provides compounds of Formula (I), and methods of treating or preventing a bacterial infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufactur...  
WO/2014/176636A9
The invention provides compounds of Formula (I), and methods of treating or preventing a bacterial infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufactur...  
WO/2014/147568A8
S-adenosyl methionine, and the salts and complexes thereof, in the form of a spray-dried sterile powder which has a pharmacologically active enantiomer content exceeding 70% and a water residue below 2.5% by weight.  
WO/2014/147568A1
S-adenosyl methionine, and the salts and complexes thereof, in the form of a spray-dried sterile powder which has a pharmacologically active enantiomer content exceeding 70% and a water residue below 2.5% by weight.  
WO/2014/108520A1
The present invention relates to a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof, wherein:R1 is alkyl, Cl, F or Br; R2 is H or F; R3 is selected from H and alkyl; R4 is selected from H and C(O)R...  
WO/2014/077363A1
A semicarbazide composition which comprises a semicarbazide compound (A) having an amino group and a semicarbazide group, a semicarbazide compound (B-1) in which the amino group of the semicarbazide compound (A) has been substituted by a...  
WO/2014/027009A1
The present invention relates to a novel process for the preparation of a pyrazole carboxylic acid derivative of the formula (I) wherein R1 is C1-7-alkyl and R3 is C1-7-alkyl which is optionally substituted with halogen or C1-4-alkoxy. T...  
WO/2014/019044A1
The invention relates to hydrazide-N-acylhydrazone compounds, to a method for producing hydrazide-N-acylhydrazone compounds, to the use of intermediate compounds for producing hydrazide-N-acylhydrazones for the treatment of leishmaniasis...  
WO/2013/045487A1
The present application relates to azo compounds and also to use thereof as a mediator in a diagnostic method. In addition, the present application relates to detection reagents, kits and test elements which comprise such azo compounds.  
WO/2013/024720A1
 This catalyst is composed of a peptide and a carrier, said peptide containing an amino acid represented by formula (SAA)-(AA)-(AA2) or (SAA1)-(SAA)- (AA)- (AA2) at the N-terminus thereof. (In the formula, SAA, SAA1 independently repre...  
WO/2012/165650A1
A new method for manufacturing an isoxazoline compound represented in formula (9) (in the formula, R1 represents a C1-C12 alkyl group optionally having one or more halogen atoms, or a C3-C12 cycloalkyl group optionally having one or more...  
WO/2012/130884A1
The invention relates to a rubber composition for tyres, comprising at least a diene elastomer, an inorganic reinforcing filler, and a coupling agent linking the inorganic filler and the diene elastomer. The composition is characterised ...  
WO/2012/130885A1
The invention relates to a rubber composition for tyres, comprising at least a diene elastomer, an inorganic reinforcing filler, and a coupling agent linking the inorganic filler and the diene elastomer. The composition is characterised ...  
WO/2012/093064A1
The present invention relates to a conjugate of the formula A−R1−N (H) −N (CH2−C (=O) −R2−B) 2, in which A is a functional entity, B is a targeting entity, and R1 and R2 are identical or different and each represent a bond or...  
WO/2012/091261A1
The present invention relates to a method for manufacturing solid powder derived from carbazic acid, which involves inducing a reaction of a liquid hydrazine derivative with carbon dioxide at a high pressure of about 0.5 MPa to about 100...  
WO/2012/032257A1
The invention relates to novel guanidine derivatives in the cinnamic series of general formula (I). The invention also relates to the method for preparing said guanidine derivatives and also synthesis intermediates. Finally, the inventio...  
WO/2012/025038A1
Disclosed is a continuous manufacturing method for the synthesis of hydazo dicarbonamide. The method comprises: (1) adding hydrazine hydrate and a urea solution into an oscillating flow tube crystallizer via the mid-lower section thereof...  
WO/2011/138410A1
The present invention relates to flame retardant polymer compositions which comprise aminoguanidine phenylphosphinates and mixtures with additional flame retardants. The compositions are especially useful for the manufacture of flame ret...  
WO/2011/026193A1
The present invention relates to a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof. In particular, the present invention relates to a method treating diseases involving cell proliferation, migr...  
WO/2011/026193A8
The present invention relates to a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof. In particular, the present invention relates to a method treating diseases involving cell proliferation, migr...  
WO/2010/132509A3
The present invention relates to novel compounds and compositions and the use of them for the control of fungal and bacterial pathogens, insect pests, acari, nematodes and other invertebrate pests including, but not limited to post-harve...  
WO/2010/117064A1
A compound having a hetero ring skeleton represented by general formula (I), a tautomer of the compound, or a salt of the compound or the tautomer, which is useful as a catalyst for asymmetric synthesis. [In the formula, R1 and R2 indepe...  
WO/2010/114536A1
Disclosed herein are acylhydrazone and semicarbazones derivatives of aldehydes and ketones that may act to attract plant pathogenic zoospores and methods of using these compounds. These compounds include the compound according to Formula...  
WO/2010/096383A1
An apparatus for providing a reactant comprises a reactant space and a reservoir space. The reactant space comprises a chemical complex capable of evolving the reactant when heated. The reservoir space, in turn, is in gas communication w...  
WO/2010/084292A1
The present invention relates to azapeptide or azapeptidomimetic compounds of formula (I): where R1, R2, R3, X1, X2, X2, X4 and Y are as defined in claim 1, to the pharmaceutical compositions containing said compounds and to such compoun...  
WO/2010/060231A1
The present invention provides a kind of nitroguanidine compounds, its preparation method and uses. The structure of the compound is as follows of formular I, in which R1 is saturated or unsaturated C1-10 aliphatic alkyl, benzyl or subst...  
WO/2010/047400A1
A compound represented by formula (1). (In the formula, Ar represents an optionally substituted aromatic hydrocarbon group having 6-20 carbon atoms; Ar' represents an optionally substituted aromatic hydrocarbon group having 6-20 carbon a...  
WO/2010/000634A1
The present invention relates to a process for the isomerization of the Z-isomer I-Z of a semicarbazone compound of the general formula (I) into its E-isomer I-E wherein the variables in formula (I) have the meanings as defined in the de...  
WO/2009/148869A1
Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.  

Matches 1 - 50 out of 1,286