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JP2000219668A |
To provide an amidoamine oxide-type surface-active compound composed of a specific polyoxyalkylene amidoamine oxide compound, having low protein denaturation activity, giving low stimulation to the human skin and having excellent surface...
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JP2000509375A |
Ophthalmic pharmaceutical compositions containing a pharmaceutically acceptable ophthalmic carrier and an inflammation-treating amount of a nitrone compound are disclosed. Also disclosed are methods for treating ocular inflammation condi...
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JP3069801B2 |
Compounds of formula I wherein X is a group of formula Ia or Ib, R1 and R2 are independently e.g. hydrogen, alkyl, alkenyl, aryl or phenylalkyl, and R3 to R7 are independently e.g. hydrogen, alkyl or substituted alkyl are very effective ...
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JP2000178244A |
To produce the subject new substances produced in a culture solution of a specific microorganism which is a specified strain of an actinomyces, having an immunosuppressive activity and a cancer cell growth suppressing activity and useful...
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JP2000505803A |
(57) 2*5 pelf ルオロ alkoxy groups in which summary book invention has preferably 1*4 carbon atoms 1*2 are prolonged from the fluorination ring of the carbonyl fluoride compound, However, when one or more of a pelf ルオロ alkoxy gr...
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JP2000502355A |
Novel compounds are provided which are inhibitors of MTP and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases, and have the structure (I) or (IA) or (IB) including pharmaceutically acceptable sa...
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JP3012220B2 |
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JP3010883B2 |
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JP2000501081A |
The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective a...
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JP2998667B2 |
To obtain the subject compound which is good in both of storage stability and hue stability by reacting an aliphatic tertiary amine having a hydrocarbon group with larger carbon number or branched hydrocarbon group with an excess hydroge...
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JP2997030B2 |
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JPH11335275A |
To obtain the subject agent capable of maintaining blood medicament levels for a long time and extending the biological half-life of the levels compared to the case with oral administration or intravenous injection, and useful as a thera...
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JP2987205B2 |
PCT No. PCT/GB92/02199 Sec. 371 Date May 26, 1994 Sec. 102(e) Date May 26, 1994 PCT Filed Nov. 27, 1992 PCT Pub. No. WO93/11099 PCT Pub. Date Jun. 10, 1993 (I) The invention provides nitroaniline derivatives represented by general formul...
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JP2975587B2 |
Compositions containing as the active ingredient a spin-trapping reagent, preferably alpha -phenyl butyl nitrone (PBN) or spin-trapping derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient are disclos...
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JP2972849B2 |
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JPH11512407A |
(57) Summary book invention is the formula I. : (among a formula) A is related with the method for preparing; and these intermediate fields to use of the intermediate field of; these at the intermediate field used for; this gentleman met...
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JPH11511148A |
The amine oxides described correspond to the following formula (1) (1) in which RCO is an aliphatic acyl radical having 6 to 22 carbon atoms, Z is a linear polyhydroxyhydrocarbon radical having at least 3 optionally oxyalkylated hydroxyl...
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JP2948783B2 |
To obtain the subject liquid crystal compound bearing an antipodic haloalkyl residue, and useful for displays having a memorizing capability for displaying letters, signs or figures and quick in startup. This ferroelectric liquid crystal...
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JPH11509216A |
PCT No. PCT/EP96/02928 Sec. 371 Date Jan. 13, 1998 Sec. 102(e) Date Jan. 13, 1998 PCT Filed Jul. 4, 1996 PCT Pub. No. WO97/03946 PCT Pub. Date Feb. 6, 1997The invention relates to the preparation of organic nitrogen compounds, in particu...
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JP2935668B2 |
To obtain the subject new compound capable of inhibiting the adhesion and metamorphosis of fouling organisms such as Armina and thereby useful as an adhesion and metamorphosis-inhibiting substance capable of being utilized as an antifoul...
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JP2921676B2 |
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JP2918206B2 |
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JPH11180943A |
To obtain the subject compound useful as a curing agent for rubber, capable of readily converting a halomethyl group having relatively large steric hindrance into an aldehyde functional group in a high yield without using a chlorinated s...
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JPH11507379A |
There are disclosed N-substituted piperazine NONOate compounds having the structure: (I) wherein M is a pharmaceutically acceptable cation, x is the valence of the cation, and R is selected from the group consisting of: an unsubstituted ...
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JPH11152260A |
To produce the subject compound excellent in stability of color tone and fragrance with the passage of time at low cost by oxidizing an amidamine compound in the presence of a specific organic phosphonic acid compound. The objective comp...
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JPH1192444A |
To produce the subject surfactant having a high quality and prevent gel-formation during the production process through a smooth reaction by reacting a specific amine of a specific concentration with hydrogen peroxide in an aqueous solve...
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JPH1192443A |
To obtain the subject compound having a high conversion ratio (having a low ratio of unconverted amine) and excellent in a hue stability and storage stability by reacting a specific aliphatic tertiary amine with a specific amount of hydr...
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JP2874075B2 |
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JP2863883B2 |
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JP11049741A |
To provide a method for producing the subject compound, by which the conversion of a tertiary amine is improved and the subject compound useful as a surfactant for a detergent, etc., is produced in high concentration by reacting the tert...
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JP2854971B2 |
PCT No. PCT/GB90/01574 Sec. 371 Date Apr. 10, 1991 Sec. 102(e) Date Apr. 10, 1991 PCT Filed Oct. 12, 1990.Compounds of formula (I) (I) in which R1, R2, R3 and R4 are each separately selected from hydrogen, X, NH-A-NHR and NH-A-N(O)R'R'' ...
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JPH01129546A |
PURPOSE: To improve the transmission efficiency of the whole network by providing an address control table where the addresses of terminal devices included in its LAN are registered and sending received packets only to a LAN which includ...
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JPH01129758A |
PURPOSE: To rigidly secure an inner core piece to a predetermined position by filling thermosetting resin in a space between an outer core piece and an outer peripheral wall. CONSTITUTION: A rotor 5 and a stator 6 are contained in a rece...
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JP11029546A |
To obtain the subject compound without substantially containing nitrosamine in high yield by reacting a specific tert-amine with hydrogen peroxide and an organic carboxylic acid in a specific solvent and removing the solvent and water by...
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JP11029758A |
To obtain an additive which can reduce the friction resistance of an aq. medium in a wide temp. range by incorporating an amine oxide having a linear or branched satd. or unsatd. aliph. hydrocarbon group having the number of carbon atoms...
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JP2850627B2 |
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JP2848535B2 |
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JPH115775A |
To obtain an amine oxide good in stability for a long period and useful as a surfactant such as a washing agent by oxidizing an amide amine with hydrogen peroxide and subsequently controlling the reaction solution to a specific pH range....
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JPH111464A |
To obtain the subject new compounds capable of being a manufacturing intermediate for a dyestuff with a high brightness by reacting a nitro carboxylic acid compound with an aqueous solution of a reducing sugar. This compound is a dicarbo...
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JPH10338815A |
To provide a polymeric resin composition stabilized against decomposition. This composition comprises a stabilizing amount of a stabilizer selected from the group consisting of phenolic antioxidants, 2-arylbenzofuranones, hindered amine ...
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JPH10330346A |
To obtain the subject stable compound having an excellent spin trap ability, capable of rapidly binding it with active oxygen and a free radical even in vivo, high in safety to the living body and useful as a medicine and a reagent. This...
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JP2835073B2 |
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JPH10511404A |
The invention is directed to a method for preventing or treating the symptoms associated with sensitive skin by applying an effective amount of at least one nitric oxide synthase inhibitor to treat or prevent the symptoms associated with...
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JP2817507B2 |
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JP2816326B2 |
Compositions containing as the active ingredient a spin-trapping reagent, preferably alpha -phenyl butyl nitrone (PBN) or spin-trapping derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient are disclos...
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JPH10510249A |
A polymeric composition capable of releasing nitric oxide under physiological conditions comprises a biopolymer bound to a nitric oxide releasing N 2 O 2 - functional group of the formula: wherein J is a pyrrolidino group, bonded to N 2 ...
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JPH10259178A |
To obtain a composition capable of treating peripheral neuropathy of diabetes, vascular deformation or diabetic retinal damage by including a spin trapping compound, etc. This composition contains a compound of formula I (X is phenyl, et...
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JPH10259128A |
To obtain a composition for treatment and prevention of ischemic damage, oxidative damage and functional deficiency which relates to aging by including α-phenyl-t-butylnitron PBN) or its spin trapping derivative as an active ingredient ...
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JP2797559B2 |
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JP2795000B2 |
PURPOSE: To obtain a new nitrone compound, excellent in compatibility with resins, capable of forming fine resist patterns in high yield and useful as a principal component of a contrast enhanced material(CEM) for enhancing contrast. CON...
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