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JP4870995B2 |
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JP4863380B2 |
Novel isonitrile compounds represented by the general formula F-A-NC, their method of manufacture, a marine fouling organism larva fluorescent marker having at least one of these compounds as an active ingredient, and a method of detecti...
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JP4856295B2 |
The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitr...
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JP4856406B2 |
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JP4813704B2 |
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JP2011208117A |
To provide a crosslinking agent capable of crosslinking a polymer material such as NBR having a carbon-carbon double bond, a nitrile group or the like in the molecule, at a low temperature (for example, 20-200°C), a crosslinked polymer ...
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JP2011510002A |
New compositions of matter, described as photopolymerizable and photocleavable materials, are described in following formula, which contains one or more polymerizable groups within the monomer. The new compositions of matter are polymeri...
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JP2011505179A |
A polymerisation-curable composition for the production of biodegradable, biocompatible, crosslinked polymers, contains 5-100 wt.% special vinyl carboxylate monomer(s), vinylcarbonate monomer(s) (or corresponding monomers with sulfur, ni...
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JP4616644B2 |
The invention relates to metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethy...
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JP4602671B2 |
The present invention relates to open chain alkoxyamine compounds, a polymerizable composition comprising a) at least one ethylenically unsaturated monomer and b) at least one open chain alkoxyamine compound. Further aspects of the prese...
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JP2010280665A |
To provide a new NSAID (nitrosated nonsteroidal antiinflammatory drug), a composition and a method for using the same.There are provided an NSAID of the formula, its pharmaceutically acceptable salt, and a new composition containing at l...
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JP2010265292A |
To provide new nitrosated nonsteroidal antiinflammatory drugs (NSAIDs) and pharmaceutically acceptable salts thereof, and methods for treating inflammation, pain and fever, for treating gastrointestinal disorders, and for facilitating wo...
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JP2010531326A |
Venlafaxine-N-oxide and O-desmethylbenlafaxine-N- as prodrugs of the present invention, venlafaxine and its major (effective) metabolite, O-desmethylbenlafaxine, respectively. The present invention relates to oxides, pharmaceutical compo...
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JP4549537B2 |
The invention concerns a method for preparing nitroxides, which consists in oxidising, in a two-phase medium, using an aliphatic peroxide, secondary amines with steric hindrance or having a -CH in the nitrogen atom alpha.
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JP4544657B2 |
To provide an amidoamine oxide-type surface-active compound composed of a specific polyoxyalkylene amidoamine oxide compound, having low protein denaturation activity, giving low stimulation to the human skin and having excellent surface...
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JP4534520B2 |
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JP4531700B2 |
To provide: a carboxamide derivative having reduced content of amide ester; a method for producing thereof; and a detergent composition containing the carboxamide derivative and having excellent low-temperature stability. One method for ...
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JP2010168390A |
To provide a chemical structural framework having an atomic and electronic arrangement whose bonded N2O2-functional group is usable as a spontaneous NO and/or NO-donor.There are provided nitric oxide-releasing amidine- or enamine-derived...
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JP4472669B2 |
This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
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JP4463279B2 |
Copper (I) formate complexes of general formula LnCu(HCOO).x COOH are decomposed in order to separate metallic copper, wherein x is a number from 0 to 10, n amounts to, 2, 3 or 4 and the n ligands L represent, independent of one another,...
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JP4459268B2 |
An indene derivative for selectively modulating the activities of peroxisome proliferator activated receptors (PPARs) having the following formula (I): wherein, R1 is C1-6 alkyl, C1-6 alkenyl, or C3-6 cycloalkyl, each of which is unsubst...
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JP2010507667A |
The present invention provides novel isolated compounds characterized as metabolites or derivatives of desmethylvenlafaxine including hydroxy-DV metabolites, hydroxy-DV-glucuronide metabolites, N-oxide-DV metabolites, and benzyl-hydroxy-...
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JP2010043112A |
To provide a compound useful for treating such diseases as inflammations, cardiovascular disorders and atherosclerosis as liver X receptor (LXR)-mediated diseases or symptoms.The compound is represented by formula (I) (wherein, X is brom...
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JP2010037288A |
To provide a trifunctional nitrile oxide having three nitrile oxide groups in the molecule and exhibiting relatively good stability, and to provide a method for producing the same.The trifunctional nitrile oxide is represented by general...
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JP4412173B2 |
A preventive, therapeutic or improving agent for diseases against which activation of the thrombopoietin receptor is effective or a platelet increasing agent, which contains a thrombopoietin receptor activator represented by the formula ...
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JP4410411B2 |
The present invention relates to compounds of the general formula I wherein A is a group of the formula and Z is an O or S atom, to the further processing thereof to form novel sec-amidoalkylcarbonic acid derivatives and to those sec-ami...
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JP2010502581A |
A process for preparing a salt of compound of formula (I) wherein R1 and R2 are independently selected from an organic group other than hydrogen, said process comprising reacting a compound of formula (II) with water and an organic acid,...
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JP2009280539A |
To provide a tyrosinase-inhibiting active ingredient, a tyrosinase inhibitor and a skin-lightening cosmetic obtained by formulating the tyrosinase inhibitor.The 5-hydroxy-3-isocyano-5-vinylcyclopent-2-enone having the tyrosinase-inhibiti...
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JP2009541288A |
The invention relates to radiodiagnostic and radiotherapeutic agents, including biologically active vectors labelled with radionuclides. It further relates to methods and reagents labelling a vector such as a peptide comprising reaction ...
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JP4350391B2 |
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JP2009536152A |
One of the most universal characteristics of malignant tumors is their acidity. Onco-tools are small non-peptide synthetic molecules designed to exploit this acidity for early detection and destruction of tumors. Each onco-tool has a str...
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JP4334772B2 |
Mono-long chain amine oxide surfactants can be prepared containing active levels of greater than about 30%, by weight of amine, and with low nitrite and nitrosamine levels and low levels of residual hydrogen peroxide when oxidized under ...
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JP4327135B2 |
A polymeric composition capable of releasing nitric oxide under physiological conditions comprises a biopolymer bound to a nitric oxide releasing N 2 O 2 - functional group of the formula: wherein J is a pyrrolidino group, bonded to N 2 ...
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JP2009530398A |
The invention provides compounds and pharmaceutical compositions that can be used to treat or prevent atherosclerosis, stroke, and other ischemic vascular diseases, dyslipidemia and hypercholestcrolemia and prevent complications of these...
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JP2009173562A |
To provide a method for decomposing a nitrile or an isonitrile with fewer restrictions in reaction conditions compared to the case using an enzyme as a catalyst.The method for decomposing the isonitrile uses a metal complex (I) as the ca...
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JP4284999B2 |
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JP4285775B2 |
To provide new diazeniumdiolates, (wherein the N1position is substituted by an inorganic or organic group and the O2-oxygen is bound to a substituted or unsubstituted aromatic group). The invention provided O2-glycosylated 1-substituted ...
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JP4272722B2 |
A process is provided for the manufacture of free-flowing solid tertiary amine oxides having N-nitrosodimethylamine levels of less than about 250 ppb. The process comprises heating a mixture of a tertiary amine, a polar hydroxy alkyl sol...
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JP2009517398A |
A process for making ionic liquids containing ion actives, which provide fabric treating benefits, surface treating benefits and/or air treating benefits. The ionic liquid is made from an ion active feedstock and an ionic liquid forming ...
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JP4256160B2 |
Phenyl acetamide compounds are described, including compounds of or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R3-R6, R11, B, Y and W are set forth in the specification. The compounds of the invention are pot...
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JP2009079023A |
To provide a fluorine-containing compound effective as a surfactant exhibiting an excellent surface tension-lowering ability even at a low concentration and to provide a surfactant composition comprising the fluorine-containing compound....
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JP4244139B2 |
The present invention relates to aminocyclohexanol derivatives useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arterioscle...
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JP4236309B2 |
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JP4223688B2 |
The present invention provides a composition comprising an amine oxide and an aqueous copper amine complex. Another embodiment of the present invention is a method for preserving and/or waterproofing a wood substrate by contacting the co...
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JP4223710B2 |
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JP4220674B2 |
The invention relates to an amine derivative represented by the general formula (1): wherein R<1> is a C1-C30 hydrocarbon group which may be interrupted by an ether linkage, with the proviso that phenyl and benzyl groups are excluded; on...
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JP4209022B2 |
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JP4182741B2 |
To provide a method for industrially more advantageously producing a nitrone compound by reaction between a secondary amine (wherein, at least one of the two carbon atoms bound to the amino group has at least one hydrogen atom) and hydro...
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JP4173676B2 |
The present invention provides a process for the preparation of amine oxide by reacting a tertiary or a secondary amine with hydrogen peroxide as an oxidant in the presence of a recyclable heterogeneous catalyst comprising a layered doub...
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JP4129993B2 |
Novel compounds are provided which are inhibitors of MTP and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases, and have the structure (I) or (IA) or (IB) including pharmaceutically acceptable sa...
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