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WO/2011/151669A1 |
The present invention relates to an economic and efficient process for producing enatiomerically enriched 3-(1-aminoethyl)phenyl derivative and employing the same to produce Rivastigmine or its pharmaceutically acceptable salt.
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WO/2011/148971A1 |
A process for the preparation of fluorine-containing sulfonyl imide compounds, which includes subjecting a mixture of a fluorine-containing sulfonyl imide compound represented by (Rf1SO2)(Rf2SO2)NH (1) and a sulfonic acid compound repres...
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WO/2011/148958A1 |
A process for the preparation of fluorine-containing imide compounds represented by (Rf1SO2)(Rf2SO2)NH, characterized by reacting a fluorine-containing sulfonic acid represented by Rf1SO3H with a fluorine-containing sulfonamide represent...
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WO/2011/148961A1 |
Disclosed is a method for producing a fluorine-containing imide compound, which uses inexpensive starting materials and is highly safe and highly productive. The fluorine-containing imide compound ((Rf1SO2)(Rf2SO2)NH) is produced by reac...
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WO/2011/111762A1 |
Disclosed are a novel binaphthyl derivative, a novel formylarene derivative and a method capable of producing diaryl derivatives having an asymmetric structure or formylarenes having two specific substituent groups. Using a diformyl-diar...
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WO/2011/108563A1 |
A heat-stable solution of an alkyl methanesulfonate in an aromatic organic solvent can be prepared by: reacting an alkyl alcohol with methanesulfonyl chloride in an aromatic organic solvent in the presence of a tertiary amine; and then s...
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WO/2011/107465A1 |
The invention relates to a method for producing 4-chlorobenzene sulphonic acid from 2-chlorobenzene sulphonic acid and/or 3-chlorobenzene sulphonic acid, comprising the reaction of 2-chlorobenzene sulphonic acid and/or 3-chlorobenzene su...
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WO/2011/104724A2 |
The present invention relates to a process for the preparation of triflic acid by chloroxidation.
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WO/2011/040497A9 |
Disclosed is a method wherein RH 2ORH 1SO2F is added to hydrofluoric acid so as to form a thick solution (hydrogen bonded complex) and the solution is directly supplied to a liquid phase reaction system in which an F2 gas is used, or alt...
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WO/2011/091719A1 |
Crystalline hydrates of alkyl acyl acetaldehyde sulfites, preparation methods and uses thereof. The molecular formula of the hydrates of alkyl acyl acetaldehyde sulfites is CnH2n+1C(O)CH2CH(OH)SO3M·mH2O, wherein n=8-14, m=0.2-1.5, M is ...
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WO/2011/093497A1 |
Provided is a plasma oxidation-reduction method with which it is possible to control the structure of amino acids and proteins with high and stable reproducibility, by using plasma in order to control the amino acids and proteins that ma...
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WO/2011/093371A1 |
A process for producing a perfluorobutanesulfonic acid salt (PFBS salt) is provided with which it is possible to attain an improvement in yield and a reduction in PFOS salt content. Electrolytic fluorination is conducted in an electrolyt...
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WO/2011/077941A1 |
A radiation-sensitive resin composition comprising: a compound (A) represented by general formula (A) (wherein R1 and R2 independently represent a substituted or unsubstituted univalent hydrocarbon group having 1 to 25 carbon atoms; X an...
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WO/2011/068732A2 |
A process for preparing a highly overbased magnesium alkyltoluene sulfonates comprising: (A) reacting at least one oil soluble alkyltoluene sulfonic acid and at least one source of magnesium, in the presence of a mixture comprising: (i) ...
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WO/2011/065502A1 |
Disclosed are: a method for producing a fluorosulfonyl imide salt, which is capable of reducing the impurity content and can be continuously performed for a long time; and a fluorosulfonyl imide salt. The fluorosulfonyl imide salt has a ...
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WO/2011/062988A2 |
A process for preparing an alkylaryl sulfonate comprising (a) reacting at least one meta-xylene compound with olefin or a mixture of olefins having from about 10 to about 20 carbon atoms, in the presence of an acid catalyst, wherein the ...
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WO/2011/058789A1 |
Disclosed is a quinonediazide photosensitizer solution comprising a quinonediazide photosensitizer dissolved in an organic solvent so that the precipitation of the quinonediazide photosensitizer from a positive-type resist composition ca...
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WO/2011/058915A1 |
Disclosed is a process for producing a high-purity aromatic sulfonyl chloride compound readily, on an industrial scale, and with high efficiency. A reaction product produced by reacting sulfuryl chloride, N,N-dimethylformamide and sulfur...
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WO/2011/052601A1 |
Provided are a novel ionic organic compound represented by general formula (I), which is effective as a carbon nanotube dispersant, and a method for producing said compound by means of simple processes. (In the formula, R1, R2, and R3 re...
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WO/2011/047877A1 |
The present invention relates in general to the field of organic chemistry, and in particular to the preparation of benzo[b]thiophene derivatives. These benzo[b]thiophene derivatives are useful as intermediates in the synthesis of pharma...
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WO/2011/048535A1 |
The process of the present invention creates a sustainable and closed water loop allowing inherent recycles of all liquid streams generated in the process. The liquid streams generated during the process of the invention are inherently r...
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WO/2011/048152A1 |
The present invention relates to novel lithium salts which comprise pentafluorophenylamide anions and are of the general formula Li+[N(SO2-R)(C6F5)]-, which are optionally present as solvent-free complexes. R is selected from fluorine, l...
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WO/2011/049940A2 |
There is disclosed a process for making a mono-lithium salt of 5-sulfoisophthalic acid (LiSIPA) having less than 200 ppm sulfate. The process uses a reaction mixture of acetic acid, water, a lithium cation producing compound, and 5-sulfo...
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WO/2011/040963A1 |
The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.
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WO/2011/037975A2 |
The present invention describes the method of making anionic ether sulfate surfactants by alkoxylation of a GA using PO and/or EO followed by a sulfation reaction. The GA of the present invention is made by a facile and inexpensive metho...
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WO/2011/037613A1 |
The present invention relates to salts of 2-(2-((4-(((4-chlorophenyl)(phenyl)-carbamoyloxy)methyl)cycl
ohexyl)methoxy)acetamido)ethanesulfonic acid (Compound 1) and crystalline forms, solvates and hydrates thereof. The present invention ...
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WO/2011/030921A1 |
Disclosed are a biphenyltetrasulfonic acid compound represented by formula (1), and a polymer which contains a structural unit originating in said biphenyltetrasulfonic acid compound. In formula (1), R1 represents a hydrogen atom, a cati...
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WO/2011/027867A1 |
Provided is a method for producing bis(sulfonyl)imide ammonium salts, bis(sulfonyl)imide, and bis(sulfonyl)imide lithium salts in a simple manner and with good yield. A method for producing bis(sulfonyl)imide ammonium salts, wherein ammo...
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WO/2011/022429A2 |
The present invention relates to a process for the preparation of alkyl esters of (S) 2-amino-5-cyclopropyl-4,4-difluoropentanoic acid, which are intermediates useful in the synthesis of (S)-N-(1-cyanocyclopropyl)-5-cyclopropyl-4,4-diflu...
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WO/2011/017800A1 |
The invention relates to methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 1,3PDS, either in ...
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WO/2011/016523A1 |
Disclosed are: a process for producing a bis-quaternary ammonium salt with high efficiency; and a novel synthetic intermediate for the process. Specifically disclosed are: a process for producing a bis-quaternary ammonium salt represente...
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WO/2011/014553A2 |
Produce a sulfo-chlorinated hydrocarbon using liquid sulfur dioxide, a chlorinating agent such as chlorine or sulfuryl chloride, and a metal complex catalyst, the catalyst being represented as LnM where L is at least one of an amine, pho...
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WO/2011/013834A1 |
Disclosed is a method for producing a biaryl compound represented by formula (2): Ar-Ar, wherein Ar represents an aromatic group which can have a substituent, comprising carrying out the coupling reaction of a compound represented by for...
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WO/2011/010524A1 |
Provided is a process by which high-purity alkoxybenzenesulfonyl chlorides can be produced industrially, easily and efficiently. A process for the production of alkoxybenzenesulfonyl chlorides represented by general formula (2) [wherein ...
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WO/2011/009541A1 |
The present invention relates to the preparation of (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxy
phenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxy
p...
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WO/2011/005642A1 |
Current methods for making polyfluorosulfonamido amines, which involve the use of a diamine reactant, provide low yields and produce an undesirable fluorine containing bis-sulfonamide by-product representing an economic loss. The bis-sul...
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WO/2010/149262A1 |
The present invention relates to novel compounds having fluoridated terminal groups, to the use thereof as surfactant substances, and to a method for producing said compounds.
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WO/2010/123016A1 |
Disclosed is a compound having a GPR40 agonistic activity and useful for use in a pharmaceutical composition or useful as an insulin secretion promoter or a prophylactic or therapeutic agent for diabetes. Extensive studies have been made...
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WO/2010/123060A1 |
Provided is a fatty acid alkyl ester sulfonate metal salt mixture comprising: (a) a fatty acid alkyl ester sulfonate metal salt for which the heat-absorption peak area between 50°C and 130°C is less than 50% of the total absorption pea...
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WO/2010/118889A1 |
Process for manufacturing 1-amino-1,3,3, 5, 5-pentamethylcyclohexane mesylate comprising step (i): (i) reacting 1-amino-1, 3, 3, 5, 5-pentamethylcyclohexane with methane sulfonic acid in a solvent or a mixture of two or more solvents sel...
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WO/2010/116736A1 |
Disclosed is a method for producing an alkanolamine salt of an α-sulfo fatty acid alkyl ester, comprising: a step of sulfonating a fatty acid alkyl ester to obtain a sulfonated compound; a step of reacting an alcohol and hydrogen peroxi...
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WO/2010/114144A1 |
The present invention provides a novel propylene oxide and a method for producing the same as well as a production method using the novel propylene oxide. The present invention is 1,1,3-trichloro-2,3,3-trifluoropropylene oxide. The prese...
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WO/2010/113835A1 |
Disclosed is a method for producing "a salt or a complex comprising imidic acid and an organic base", characterized by reacting halogenated sulfuryl or halogenated phosphoryl with ammonia in the presence of an organic base. According to ...
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WO/2010/113492A1 |
Provided is a method that can safely manufacture a fluorine-containing N-alkyl sulfonyl imide compound, with high yield, by alkylating either a fluorine-containing sulfonyl imide acid or a fluorine-containing sulfonyl imidate using eithe...
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WO/2010/113458A1 |
Disclosed is a commercially advantageous method for manufacturing a 1,5-benzodiazepine compound. A compound (5) is obtained from a reaction formula and used as an intermediate.
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WO/2010/104177A1 |
A fluoroalkanesulfinic acid ammonium salt is obtained using an organic base when a bromofluoroalkyl carboxylate ester is sulfinated using a sulfinating agent. The fluoroalkanesulfinic acid ammonium salt is oxidized, thereby obtaining a f...
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WO/2010/104178A1 |
An ammonium hydroxyfluoroalkanesulfinate is obtained by using an organic base while sulfinating a bromofluoroalcohol with a sulfinating agent. An ammonium hydroxyfluoroalkanesulfonate is obtained by oxidizing said ammonium hydroxyfluoroa...
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WO/2010/099532A2 |
A method for the purification of 5-sulfoisophthalic acid wherein via the application of an acetic acid wash while said crude cake of 5-sulfoisophthalic acid is filtered.
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WO/2010/087982A1 |
The present invention provides for compositions and methods for modulating the GluR2 receptor. It is based, at least in part, on the discovery, by X- ray crystallography, that a known GluR2 agonist binds to the receptor in two different ...
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WO/2010/084976A1 |
Disclosed is a method for manufacturing a conjugated aromatic compound, which is characterized in that an aromatic compound (A), wherein one or two leaving groups selected from a group comprised of an iodine atom, bromine atom and chlori...
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