| Document |
Document Title |
|
WO/2002/102250A1 |
A positron emission tomography (PET)-ready library of candidate pharmaceutical agents is provided which can be prepared by a multistep process wherein the final or penultimate step is a reaction using a PET-ready reagent or a plurality o...
|
|
WO2001023352A9 |
Disclosed is a process for the oxidation of sulphonamides of formula (I) to N-sulphonyl imines of formula (II) using chromium (IV) dioxide as the oxidant. Also disclosed is a process for the preparation of imines of formula (iii) or comb...
|
|
WO/2002/098844A1 |
The invention relates to a method for producing perfluoroalkanesulfonic acid esters and for further transforming the same into the salts thereof. The invention also relates to the use of the produced compounds in electrolytes, batteries,...
|
|
WO/2002/098845A1 |
A process for preparing (S)-(-)-N-[4-[4-[ethyl(6-fluoro-6-methylheptyl)amino]-1-hydr
oxy]phenyl]methanesulfonamide hemifumarate salt, which comprises reacting N-[4[(2S)-tetrahydro-5-hydroxy-2-furanyl]phenyl]methanesulfo
namide (IIa) with...
|
|
WO/2002/096865A1 |
A process for the preparation of a compound of formula (I) in which R represents H or an acid protecting group which comprises reacting a compound of formula (II) in which R is as previously def ined with a compound of formula (III) wher...
|
|
WO/2002/092557A1 |
The invention relates to a method for producing 2-trifluoromethoxy-benzole sulphonamide of formula (I) exhibiting very good yields and a high degree of purity by reacting trifluoromethoxy-benzole of formula (II) with a cross-linked alkyl...
|
|
WO/2002/092556A1 |
Sulfonamide derivatives of the formula I wherein R?1¿-R?6¿ are as defined in the description, processes for their production, their use as pharmaceuticals, particularly for use in the treatment or prevention of diseases in which bradyk...
|
|
WO/2002/090297A1 |
A process that can be used for sulfonating, sulfating, or sulfamating an organic compound is disclosed. The process can comprise, consist essentially of, or consist of, contacting the organic compound with sulfur trioxide under a conditi...
|
|
WO/2002/090324A1 |
The present invention relates to a process for effectively preparing prostaglandin derivatives and to a stereospecific alkyl halide containing 15S-alcohol group as a starting material.
|
|
WO/2002/090306A1 |
This invention relates to a process for the production of the cyclic ketone (1R,5S)-bicyclo[3.2.0]heptan-3-one. This compound is useful inter alia as an intermediate for the synthesis of analogues of gabapentin (Neurontin®). The reactio...
|
|
WO/2002/088072A1 |
The invention provides an industrially advantageous process for preparation of 3-methoxydecanol derivatives, specifically a process for preparation of compounds represented by the general formula (5), salts thereof, or hydrates of both, ...
|
|
WO/2002/088115A1 |
The present invention relates to a novel sulfonamide derivatives and novel intermediates thereof, preparation thereof, and a pharmaceutical composition comprising the same, and more particularly, to novel sulfonamide derivatives and inte...
|
|
WO/2002/087725A1 |
A method for reducing malodors in hydrotropes, such as alkyl aryl sulfonates, is provided that reduces and/or eliminates some or all of the detectable residual odoriferous compounds from hydrotropic compositions using a malodor treatment...
|
|
WO2001047866A9 |
The invention relates to substituted 1 and 2 naphthol Mannich bases, a method for the production thereof, medicaments containing said compounds and the use of said compounds in the production of medicaments.
|
|
WO/2002/085838A1 |
The present invention relaters to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the ...
|
|
WO/2002/085845A2 |
The invention relates to complex mixtures of sulfogroup-containing esters of polybasic organic acids with long-chain alkanols, alkoxyalkanols and diols, especially viscous oils obtained from oxosynthesis. The invention also relates to th...
|
|
WO/2002/083608A2 |
This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides ca...
|
|
WO/2002/081431A1 |
The invention relates to a method for preparing sulphinic perfluoroalkane acid salts. The inventive method is characterised in that it comprises at least one step involving the reaction of least one perfluoroalkyl halide having formula R...
|
|
WO/2002/081081A1 |
The invention relates to a composition comprising at least one amine-containing compound and ammonium bifluoride, the use thereof as a fluorinating agent and a method for preparing perfluoroalkanesulphonyl fluoride using said fluorinatin...
|
|
WO/2002/079122A2 |
This invention relates to the method of placing a sulfone or sulfonamide group ortho to a phenol in a drug substance in order to increase the metabolic stability and the half-life of the compound, while maintaining the acidity of the phe...
|
|
WO/2002/076964A1 |
The invention relates to compounds having formula (I). Said compounds have an affinity for bradykinin receptors with a selectivity for B¿1? receptors and they can be used to prepare medicaments that are intended to treat or prevent pers...
|
|
WO/2002/076932A1 |
A process is disclosed by which optically active amino compounds can be enantio-selectively prepared by aminating C-H bonds of organic compounds. An optically active amino compound can be prepared by converting the allylic C-H bond of an...
|
|
WO/2002/076375A2 |
The present invention relates to an improved process for the preparation of trifluoromethanesulfonic ester of ethyl (R)-2-hydroxy-4-phenylbutyrate, referred to here as triflate in structural Formula I, and to the use of this compound as ...
|
|
WO/2002/074834A1 |
A process for producing a partially esterified SIPA such as an alkali metal sulfoisophthalic acid in a glycol is disclosed. The partially esterified SIPA in a glycol can be used to copolymerize with oligomer of terephthalic acid dimethyl...
|
|
WO/2002/072542A2 |
NMDA receptor blockers, including pH-sensitive NMDA receptor blockers, are provided as neuroprotective drugs that are useful in stroke, traumatic brain injury, epilepsy, and other neurologic events that involve acidification of brain or ...
|
|
WO/2002/070492A1 |
An asymmetric synthesis of diarylmethylpiperazines is described. The synthetic route enables preparation of a variety of enatiomerically pure amines with different N-alkyl groups. The invention includes an asymmetric addition of organome...
|
|
WO/2002/070470A2 |
The present invention is directed to benzophenone compounds of formula (IA) in which the variables are as defined in the claims, useful in the inhibition of HIV reverse transcriptase, particularly its resistant varieties.
|
|
WO/2002/068504A1 |
The invention relates to addition compounds of formula (1) in which: n is a number from 1 to 10; Z represents a group -CH¿2?-CH¿2?-, -CH¿2?-CH(CH¿3?)-, -CH(CH¿3?)-CH¿2?- or a combination thereof; s is number from 1 to 200; B repres...
|
|
WO/2002/067865A2 |
N-(Aryl)-2-arylethenesulfonamides and pharmaceutically acceptable salts and compositions thereof are useful as antiproliferative agents, including, for example, anticancer agents. They are also useful as radioprotective agents.
|
|
WO/2002/068382A1 |
The present invention relates to a novel process for preparing sulfamoyl-substituted phenethylamine derivatives, specifically, 5-{2-[2-(2-alkoxy-phenoxy)ethylamino]-propyl}-2-methoxy-benz
ene sulfonamide of the formula (1).
|
|
WO/2002/064707A2 |
A process for preparing branched alkyl aromatic hydrocarbons, which process comprises contacting branched olefins within an aromatic hydrocarbon under alkylating conditions, which branched olefins have been obtained by a process which co...
|
|
WO/2002/064532A2 |
A process for preparing branched olefins which process comprises dehydrogenating an isoparaffinic composition comprising 0.5 % or less quaternary aliphatic carbon atoms over a suitable catalyst, which isoparaffinic composition comprises ...
|
|
WO/2002/062769A2 |
The present invention provides a new process and intermediates for the production of antiviral compound 4',4-bis-{4,6-bis-[bis-carbamoyl-methyl-1-sulfamoyl)phenylam
ino]-[1,3,5]triazin-2-ylamino}-biephenyl-2,2'-disulfonic acid and its ph...
|
|
WO/2002/060846A1 |
The invention discloses a method for converting alkane to oxygenate which comprises the following steps: (i) contacting an alkane-containing gas with non-metal, regenerable, electrophile ions in a concentrated sulfuric acid medium under ...
|
|
WO/2002/060862A1 |
This invention pertains to novel methods for the synthesis of certain nitrogen mustard prodrugs, such as N-{4-[N,N-bis(2-haloethylamino)-phenoxycarbonyl}-L-glutamic acid: wherein: X¿2? is a halo group, and is -F, -Cl, -Br, or -I; n is a...
|
|
WO/2002/059342A1 |
A method of producing (S)-3-[2-{(methylsulfonyl)oxy}ethoxy]-4-(triphenylmethoxy)-1
-butanol methane sulfonate using 1,3-butadiene and a ketoethanal to form an intermediate racemic mixture. The racemic mixture is resolved to remove one is...
|
|
WO2001002332A9 |
3,3-Dimethylbutanal is prepared from 3,3-dimethylbutanol. Intermediate 3,3-dimethylbutanol is obtained by reacting ethylene, isopropylene and a mineral acid to produce a 3,3-dimethylbutyl ester which is hydrolyzed to the alcohol. The hyd...
|
|
WO/2002/055483A1 |
An anilide is reacted with an acylating agent by using as a catalyst a tri(perfluoroalkane sulfonate) compound of any of the elements belonging to the groups 3 to 5 and the groups 13 to 15 in the periods 4 to 6 of the periodic and thus t...
|
|
WO/2002/053494A1 |
The invention concerns a fluorination method for obtaining fluorinated compounds. The method consists in reacting with an ionic fluoride of a monovalent cation a compound of formula (I), wherein: M represents H, an alkaline metal, a quat...
|
|
WO/2002/053518A2 |
A process for preparing a halogenated aliphatic-$g(a),$g(b)-unsaturated-$g(b)-nucleophile-function
alized carboxylate ester having the formula: R?1¿-C(-Nu)=CH-COOR?8¿ by reacting a nucleophile with a halogenated aliphatic-$g(a),$g(b)-u...
|
|
WO/2002/051782A1 |
A method for preparing a fullerene derivative, wherein a fullerene derivative having a group capable of liberating a proton introduced to a carbon atom constituting the fullerene molecule is formed by using a halogenated fullerene formed...
|
|
WO/2002/048099A1 |
The invention relates to compounds of formula (I), wherein the variables have the following meanings: D means a phenyl or a pyridyl which is unsubstituted or is mono- or polysubstituted by Hal, A, OR?2¿, N(R?2¿)¿2?, NO¿2?, CN, COOR2 ...
|
|
WO/2002/044138A1 |
A process by which a fluorosulfonyl fluoride compound useful as, e.g., a material for ion-exchange membranes can be efficiently produced at low cost without structural limitations while eliminating difficulties in production. The process...
|
|
WO/2002/044111A1 |
A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal hydrocarbyl complex which is coordinated to defined bidentate ligands substituted with at least one group selected from an optionally...
|
|
WO/2002/044114A1 |
The production of alkyl aryl compounds can be achieved by the following steps: 1) production of an olefin mixture, comprising, as a statistical mean, predominantly single-branched C¿10-14? olefins, by means of a) reaction of a C¿4? ole...
|
|
WO/2002/042845A2 |
This invention relates to new photoacid generator compounds and photoresist compositions that comprise such compounds. In particular, the invention relates to photoacid generator compounds that generate an $g(a),$g(a)-difluoroalkyl sulfo...
|
|
WO/2002/042260A1 |
The invention concerns a method for making an alkanesulphonyl chloride by photochemical reaction of an alkane with chlorine and sulphur dioxide, which consists in using as light source an indium-doped medium-pressure mercury lamp.
|
|
WO/2002/040447A2 |
Process for preparing benzenesulfonate salts from an appropriately substituted acid chloride and a hydroxybenzenesulfonic acid is conducted in the absence of solvent, in a molar excess of acid chloride and in the presence of a phase tran...
|
|
WO/2002/040491A1 |
3,3'-substituted chiral biaryl phosphine and phosphinite ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes are useful as catalysts in asymmetric reactions, such as,...
|
|
WO/2002/036556A2 |
The present invention relates to acylaminoalkyl-substituted benzenesulfonamide derivatives of formula (I), in which A, R(1), R(2), X, Y and Z have the meanings indicated in the claims. The compounds of formula (I) are valuable pharmaceut...
|
