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Matches 1,201 - 1,250 out of 9,593

Document Document Title
WO1999043285A3
The present invention provides novel sulphonamide derivatives which are useful for potentiating glutamate receptor function in a mammal requiring treatment, processes for their preparation, and pharmaceutical compositions containing them.  
WO/1999/062871A1
Novel 3-aryl proprionic acid derivatives and analogs, having general formula (I) and stereo- and optical isomers and racemates thereof as well as pharmaceutically acceptable salts, solvates and crystalline forms thereof, process for thei...  
WO/1999/062864A1
A process is described for the stereoselective synthesis of R-(-)-carnitine in which the characterising step is condensation of glycerol with an amine of (-)camphorsulphonic acid.  
WO/1999/061415A1
An improved process for sulphonation of organic compounds, notably hydroxybenzene and alkylbenzene compounds, comprises reacting them with sulphuric acid or oleum in the presence of an organic solvent, notably an n-alkane or a cycloalkan...  
WO/1999/058630A1
The invention relates to a method for producing low-odour alkyl sulfate granulates and to their use for producing laundry and dishwashing detergents, cleaning products and cleansing cosmetics.  
WO/1999/055666A1
The present invention provides a method of converting a hydroxy group in alcohols containing an electron withdrawing group into perfluoroalkanesulphonate and fluorosulphonate esters, which are good leaving groups, with inversion of confi...  
WO/1999/054292A1
The invention concerns novel sulphonated and oxy- or polyalkylene diphenol derivatives and their corresponding salts corresponding to general formulae (Ia and Ib) wherein Y¿1? and Y¿2? are such as defined in Claim 1.  
WO/1999/052862A1
The present invention relates to a process for the preparation of compounds of formula (b), in which a compound of formula (V) is reacted with a compound of formula (VI). The resulting compound of formula (IV) is reduced to a compound of...  
WO/1999/047488A1
A process for producing L-valine benzyl ester p-toluenesulfonate which involves the steps of reacting L-valine with benzyl alcohol in at least one aromatic solvent selected from among toluene, monochlorobenzene and xylene in the presence...  
WO/1999/047495A1
A process for the preparation of sulphonated distyryl-biphenyl compounds of formula (1), in which R¿1? and R¿2?, independently, are hydrogen, C¿1?-C¿5?-alkyl, C¿1?-C¿5?-alkoxy or halogen, and M represents Li, K, an alkaline earth m...  
WO/1999/046242A1
Compounds represented by formula (1a) or salts thereof, which are preventives/remedies for heart diseases, autoimmune diseases, inflammatory diseases, septic shock, etc., wherein R represents an optionally substituted aliphatic hydrocarb...  
WO/1999/043285A2
The present invention provides novel sulphonamide derivatives which are useful for potentiating glutamate receptor function in a mammal requiring treatment, processes for their preparation, and pharmaceutical compositions containing them.  
WO1998022435A9
The invention concerns a reagent and a family of compounds. The reagent contains by successive or simultaneous addition: a material of formula RfH, a silicophilic base, a trivalent nitrogenous derivative containing no hydrogen and at lea...  
WO/1999/040096A1
A method for the synthesis of certain N-silylated cyclopentaphenanthrene (Group IV metal) complexes is disclosed.  
WO/1999/038828A1
A process for producing a butanetriol derivative represented by formula (1) useful as a material for medicines, characterized by reacting a compound represented by formula (3), wherein R?1¿ and R?2¿ represent different protecting group...  
WO/1999/039245A1
The present invention provides for process of preparing a photoactive ester compound of high purity using a solid base catalyst, preferably an anionic exchange resin. The invention further provides for preparing and imaging a photosensit...  
WO/1999/038855A1
Highly pure optically active threo-3-amino-1,2-epoxy compounds appropriate for materials for manufacturing drugs and a process for producing the same on an industrial scale. An optically active threo-3-amino-1,2-diol derivative is subjec...  
WO/1999/035121A1
The invention relates to a method for producing (S,S)-N,N'-ethylenediamine disuccinic acid or analogous compounds or salts thereof by reacting L-asparaginic acid, L-glutaminic acid or L-cysteic acid with 1,2-bissulfooxyethane, 1,3,2-diox...  
WO/1999/035122A1
The invention relates to a method for producing N-(3-amino-4-fluorophenyl)- sulphonamides, N-(3-amino-4-fluorophenyl) carboxylic acid amides and N-(3-amino-4-fluorophenyl) carbamates of general formula (I), wherein A stands for SO¿2?, C...  
WO/1999/034806A1
This invention provides novel compounds derived from a marine sponge, $i(Adocia sp.), that specifically modulate kinesin activity by targeting the kinesin motor domain and mimicking the activity of a microtubule. The compounds act as pot...  
WO/1999/032438A1
A process for producing a naphthoquinone diazide ester of a phenolic compound that is useful in a photoresist composition, which process comprises providing a naphthoquinone diazide ester solution in an organic polar solvent; adding the ...  
WO/1999/029315A1
Compositions, syntheses, formulations and methods for treating or protecting the retina of a mammalian eye by contacting, with the retinal tissue, a therapeutically effective amount of retinyliden tauret (3,7-dimethyl-9-(2,6,6-trimehyl-1...  
WO1999009004A3
The present invention relates to a process for the preparation of a purified salt of 4-sulfophenyl-[(1-oxyalkanoyl)amino] alkanoate. The process comprises the steps of: (a) providing a source of 4-sulfophenyl-[(1-oxyalkanoyl)amino] alkan...  
WO/1999/025804A1
The present invention provides to a process for producing sulfate and sulfonate surfactant pastes suitable for use in surfactant containing compositions, especially clear, translucent surfactant containing compositions wherein color form...  
WO/1999/024030A1
Triene-containing compounds which mimic the chemical and/or biological activity of the spongistatins are provided, as are methods and intermediates useful in their preparation.  
WO/1999/024139A1
A process for separating a compound from a mixture of different compounds is disclosed for compounds comprising at least two negatively charged groups connected by a linker group. The process comprises treating the mixture with a materia...  
WO/1999/024381A1
A method of efficiently removing the protective group from a protected hydroxyl or amino group with an allyl derivative by one-step reaction under neutral conditions. A protected hydroxyl or amino group is converted into a free hydroxyl ...  
WO/1999/022858A1
A method of reacting an aromatic compound with an immiscible reacting agent involves the passage of the reactant along a flow path having a width of from 10 to 1000 $g(m)m in such a way that essentially laminar flow of the reactant takes...  
WO1999007656A3
Processes for making particularly branched, especially monomethyl-branched or nongeminal dimethyl-branched surfactants used in cleaning products; preferred processes comprising particular combinations of two or more adsorptive separation...  
WO/1999/018064A1
The invention concerns a method for functionalizing a phenolic compound bearing an electron-donor group, in said group para position, inter alia a method for the amidoalkylation of a phenolic compound bearing an electron-donor group, and...  
WO1999003823A3
Novel inhibitors of polyamine transport having inhibition constants two orders of magnitude lower than those of known compounds are disclosed. These polyamine analogues are useful pharmaceutical agents for treating diseases where it is d...  
WO/1999/016809A1
The invention provides a method for preparing a desired organic compound by reacting one or more reactants in a reaction medium comprising a fluorinated ether compound wherein the fluorinated ether compound comprises at least 3 carbon at...  
WO/1999/016743A1
The present invention relates to a process for preparing $i(o)-(carboalkoxy) phenylmethanesulfonyl chloride derivatives and more particularly to a novel process for preparing $i(o)-(carboalkoxy)phenylmethanesulfonyl chloride expressed by...  
WO/1999/014192A1
The salt of a sulfonated succinic acid is cyclized, then converted to novel sulfonated hydroxamic acids by reaction with hydroxylamine (which is added or formed $i(in situ)), and the novel hydroxamic acid is then cyclized to the sulfo-N-...  
WO/1999/012916A1
The instant invention is a series of benzothiazine dioxides, or a pharmaceutically acceptable salt thereof, which are potent endothelin A antagonists with profound in vitro activity, and improved syntheses for Formula (1). The compounds ...  
WO/1999/010319A1
The invention relates to a method for producing fatty acid polyglycol ester sulphates of formula (I) R?1¿COO(AO)¿n?SO¿3?M, wherein R?1¿CO represents a linear or branched, aliphatic, saturated and/or unsaturated acyl radical with 6 to...  
WO/1999/009004A2
The present invention relates to a process for the preparation of a purified salt of 4-sulfophenyl-[(1-oxyalkanoyl)amino] alkanoate. The process comprises the steps of: (a) providing a source of 4-sulfophenyl-[(1-oxyalkanoyl)amino] alkan...  
WO/1999/007793A1
Various classes of dyes are provided having acid, ester or amide groups for covalent linking to biomolecules. The dyes may be prepared by use of a compound of formula (I) where R?1¿ comprises a linker and a carboxy including acid, salt,...  
WO/1999/007656A2
Processes for making particularly branched, especially monomethyl-branched or nongeminal dimethyl-branched surfactants used in cleaning products; preferred processes comprising particular combinations of two or more adsorptive separation...  
WO/1999/006363A1
The invention relates to a method for sulfochlorinating acetanilide, characterised in that the acetanilide is introduced into a reaction vessel in fused form and then reacted with chlorosulfonic acid and thionyl chloride. The intermediat...  
WO/1999/005082A1
The present invention is in the field of processes for making alkylbenzenesulfonate surfactants. The processes herein include a combination of two essential steps, delinearization and alkylation. The delinearization step selected herein ...  
WO/1999/005084A1
The present invention is in the field of processes for making modified alkylbenzenesulfonate surfactants and of the products of such processes, including the surfactant compositions and consumer cleaning products, especially laundry dete...  
WO/1999/005098A1
The invention relates to a method for producing N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides. In a first step, 2-amino-4,5-difluoro-benzonitrile is reacted with sulphonic acid halogenides in the presence of an acid acceptor and a di...  
WO/1999/005087A1
A process for the preparation of a compound of general formula (I), wherein R?1¿ is hydrogen or C¿1?-C¿6? alkyl, C¿2?-C¿6? alkenyl or C¿2?-C¿6? alkynyl, any of which may optionally be substituted with one or more substituents sele...  
WO/1999/005241A1
Cleaning compositions, especially laundry detergents and the like comprising: (i) modified alkylarylsulfonate surfactants, e.g., modified alkylbenzenesulfonates, which are the product of particular processes and (ii) cleaning adjuncts su...  
WO/1999/003823A2
Novel inhibitors of polyamine transport having inhibition constants two orders of magnitude lower than those of known compounds are disclosed. These polyamine analogues are useful pharmaceutical agents for treating diseases where it is d...  
WO/1999/000358A1
This invention relates to a procedure to prepare N,N-dimethylaminoethanol 2-chlor-4-dimethyl-amidosulfonyl-fenoxyacetate hydrochloride of formula (1). This compound is the active principle of ROMENERG drug (Meclosulfonat) having a psycho...  
WO/1998/052886A1
The invention concerns a method of sulphonation characterised in that it consists in contacting a nucleophile whose nucleophilic atom is a nitrogen atom with a reagent comprising by successive or simultaneous addition: a heavy sulphonyl ...  
WO/1998/047844A1
The invention relates to a single-stage method for producing $g(a)-hydroxy ethers corresponding to formulae (I) and (II), by oxidizing olefinic substrates with organic hydroperoxides and opening the resulting oxirane ring by means of mon...  
WO/1998/046711A1
The invention relates to a method for producing sulfated fatty acid esters with a reduced electrolyte content, whereby a) unsaturated fatty acid esters are saturated with low alcohols or glycerin with sulfuric acid or fuming sulfuric aci...  

Matches 1,201 - 1,250 out of 9,593