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Patent Searching and Data


Matches 401 - 450 out of 10,224

Document Document Title
WO/2010/028088A3
Provided are sulphur-linked compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.  
WO/2010/028088A2
Provided are sulphur-linked compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.  
WO/2010/023448A1
The present invention provides a compound of formula (I) or its salts or pharmaceutically acceptable derivatives thereof wherein; X1 is selected from a group consisting of CH2, C(=O), C(=NH), NC(=O), R1 is selected from the group consist...  
WO/2010/023446A1
The present invention provides a compound of formula (I) or its salts or pharmaceutically acceptable derivatives thereof wherein; X1 is selected from a group consisting of CH, O or N; R1 is selected from the group consisting of optionall...  
WO/2010/020719A1
The present invention relates to the compound of formula (I) and to the use thereof as an intermediate for the synthesis of the compound of formula (A) or pharmaceutically acceptable salts thereof: formulae (II).  
WO/2010/018113A3
The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein R1-R5, A, B, Q, W, and X are defined in the detailed description and claims. In addition, the present inventio...  
WO/2010/018112A3
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates ...  
WO/2010/018112A2
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates ...  
WO/2010/018113A2
The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein R1-R5, A, B, Q, W, and X are defined in the detailed description and claims. In addition, the present inventio...  
WO/2010/018109A2
The invention is concerned with the compounds of formula (I), and pharmaceutically acceptable salts and esters thereof, wherein R1-R4 are defined in the detailed description and claims. In addition, the present invention relates to metho...  
WO/2010/018109A3
The invention is concerned with the compounds of formula (I), and pharmaceutically acceptable salts and esters thereof, wherein R1-R4 are defined in the detailed description and claims. In addition, the present invention relates to metho...  
WO/2010/015655A1
There are described cyclohexyl amide derivatives useful as corticotropin releasing factor (CRF1) receptor antagonists.  
WO/2010/017470A1
The present invention is directed to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (A) are defined herein. Also described is a pharmaceutical composi...  
WO/2010/015613A1
The present invention relates to compounds of Formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain ...  
WO/2010/013567A1
Disclosed is a pest control agent having an excellent effect, which contains, as an active ingredient, a compound represented by general formula (1). (In the formula, A represents a carbon atom, a nitrogen atom or the like; K represents...  
WO/2010/009508A1
A compound of Formula (A) wherein Z is an aryl, substituted aryl, heteroaryl, or substituted heteroaryl, wherein the heteroaryl or substituted heteroaryl connected to a 2,4-dinito-6-(trifluoromethyl)phenyl ring via a carbon-carbon bond.  
WO/2010/010079A1
The invention relates to aryl-sulphonamido compounds endowed with affinity against metallo proteases MMP, having formula (I) below wherein R, R1, R2, R3, G and n have the meanings reported in the specification, properly labelled with dia...  
WO/2010/010080A1
The invention relates to dimeric aryl-sulphonamido compounds endowed with inhibitory activity against metalloproteases MMP, having formula (I) below (M)-L-(M') (I), wherein M and M', the same or different from each other, represent the r...  
WO/2010/007027A1
The present invention provides a compound of formula (I) said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP- 13....  
WO/2010/009068A2
The present application describes modulators of MCP-1 or CCR-2 of formula,(I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R1, R2, R4 and R6, are defined herein. In addition, methods o...  
WO/2010/009068A3
The present application describes modulators of MCP-1 or CCR-2 of formula,(I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R1, R2, R4 and R6, are defined herein. In addition, methods o...  
WO/2010/004580A2
The present invention provides a process for the preparation of indole derivatives, specifically N- methyl-1H-indole-5-ethanesulfonamide of formula (I), involving novel intermediate, which is used as key intermediate for the synthesis of...  
WO/2010/004580A3
The present invention provides a process for the preparation of indole derivatives, specifically N- methyl-1H-indole-5-ethanesulfonamide of formula (I), involving novel intermediate, which is used as key intermediate for the synthesis of...  
WO/2010/004957A1
Disclosed is a novel chiral iridium aqua complex having good storage stability, which can be easily produced. The chiral iridium aqua complex can achieve a high yield and a high stereoselectivity in an asymmetric transfer hydrogenation ...  
WO/2009/157399A1
Disclosed is a compound useful as an EP1 receptor antagonist. Studies are made on EP1 receptor antagonists, and it is confirmed that a compound having a sulfonamide structure in which a nitrogen atom in the sulfonamide structure is subst...  
WO/2009/157418A1
Disclosed is a highly safe agent for treating and/or preventing diabetes or the like, which has excellent activity. Specifically disclosed is a compound represented by general formula (I) or a pharmacologically acceptable salt thereof. (...  
WO/2009/155362A1
Compounds with physiological effects, such as the activation of hematopoietic growth factor receptors, are disclosed. These compounds can be used to treat a variety of conditions, diseases and ailments, including hematopoietic conditions...  
WO/2009/153457A3
The subject matter of the present invention is novel families of compounds which are aromatic amine, imine, aminoadamantane and benzodiazepine derivatives, medicaments comprising same and the use thereof as inhibitors of the toxic effect...  
WO/2009/149807A1
The present invention relates to compounds of the formulae (I), (II) and (III), to the use of compounds containing at least one perfluoro-tert-butoxy group and at least one substituted or unsubstituted aromatic end group as surface-activ...  
WO/2009/148052A1
Disclosed is a sulfonamide compound represented by general formula (1) that can be used as an effective component in a CaSR antagonist that is extremely effective in preventing and/or treating bone diseases, such as osteoporosis. Said co...  
WO/2009/146871A1
The use of compounds of the formula (I) Ar1-L1-Ar2-L2-C(R3)(R4)N(OR1)C(=Y)-R2 (I) where Y is selected from O or S; R1 is H, a salt or readily hydrolysable substituent; R2 is selected from H or CH3, CH2F, CF2H or CF3; R3 and R4 are select...  
WO/2009/147632A3
The invention provides a method of preparing the stereoisomers of 1,11-diamino-6-aza- undecane-2,4,8,10-tetraol.  
WO/2009/148600A8
This invention relates to novel lysine-based compounds, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use o...  
WO/2009/148600A2
This invention relates to novel lysine-based compounds, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use o...  
WO/2009/147632A2
The invention provides a method of preparing the stereoisomers of 1,11-diamino-6-aza- undecane-2,4,8,10-tetraol.  
WO/2009/148600A3
This invention relates to novel lysine-based compounds, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use o...  
WO/2009/145219A1
Disclosed is a means for treating Alzheimer's disease, which utilizes a secretase inhibitor and is highly safe. Specifically disclosed is a compound represented by general formula (I) [wherein A represents a phenyl group or the like; R1...  
WO/2009/145989A3
Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described here...  
WO/2009/145989A2
Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described here...  
WO/2009/144344A2
Compound for labelling biomolecules based on vinylsulphone, preparation and uses, comprising a labelling molecule and a vinylsulphone group. In addition it relates to the use of the compounds as labelling agents, to the procedure of obta...  
WO/2009/144344A3
Compound for labelling biomolecules based on vinylsulphone, preparation and uses, comprising a labelling molecule and a vinylsulphone group. In addition it relates to the use of the compounds as labelling agents, to the procedure of obta...  
WO/2009/140743A3
The invention generally relates to the application of imaging techniques, in particular positron emission tomography (PET) or single photon emission tomography (SPECT), in the assessment of physiological parameters in a subject. The comp...  
WO/2009/142984A1
Disclosed is a compound of formula (I). Wherein R1, R2 Ar and Cy are as defined herein, or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions of the compound of formula (I), methods of making the c...  
WO/2009/138758A2
There is provided compounds of formula (I), wherein ring A, D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of disease...  
WO/2009/138758A3
There is provided compounds of formula (I), wherein ring A, D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of disease...  
WO/2009/136608A1
Disclosed is an ionic liquid having a low viscosity, a low melting point, high electrical conductivity and high thermal stability. The ionic liquid is composed of fluorosulfonyl(trifluoromethylsulfonylamide) (FTA) anions and cations of ...  
WO/2009/136617A1
Disclosed is a process for producing a compound having an antagonistic activity on a NPYY5 receptor. Also disclosed is a useful crystal. A compound represented by formula (II) [wherein R1 represents a substituted or unsubstituted alkyl;...  
WO/2009/132241A3
Materials are provided that may be useful as ionomers or polymer ionomers, including compounds including bis sulfonyl imide groups which may be highly fluorinated and may be polymers.  
WO/2009/131065A1
Disclosed is a compound useful as a prophylactic agent or a therapeutic agent for cardiovascular diseases, nervous system diseases, metabolic diseases, genital diseases, gastrointestinal diseases, neoplasm, infectious diseases and others...  
WO/2009/128088A2
The present patent application relates to a process for the preparation of 2-(2-Alkoxy phenoxy) ethylamine or a salt thereof, which is a useful intermediate in the preparation of several active pharmaceutical ingredients including Carved...  

Matches 401 - 450 out of 10,224