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Patent Searching and Data


Matches 751 - 800 out of 10,878

Document Document Title
WO/2006/033446A1
The present invention relates to a compound of the formula [I]: wherein (a), in which -Y-, R4, R5 and R6 are4 R5 each as defined in the description, etc., R1 is hydrogen, halogen, lower alkyl, hydroxy, etc., R2 is hydrogen, lower alkyl o...  
WO/2006/032386A1
The invention relates to a lyophilisate containing N-diaminomethylene-2-methyl-4,5-di-(methylsulfonyl)-benzamid e as an active ingredient. The preparation has a longer storage stability even at higher temperatures and can be applied as a...  
WO/2006/034004A2
The present invention is directed to a process for preparing certain cysteine protease inhibitors.  
WO/2006/030278A1
The present invention is directed to a process for the isolation of the enantiomeric forms of modafinil with high enantiomeric purity and high overall yields by means of a continuous chromatographic process.  
WO2005121078A3
The invention relates to substituted cyclopentene compounds of general formula (I), to a method for the production thereof, medicaments containing said compounds, in addition to the use thereof in the production of medicaments.  
WO/2006/029436A1
The invention relates to the compounds of the general formula (I), wherein X = -CH- or -N=, n = 0 or 1, R1 = -H, -F, -OCH3 or -COOCH3, R2 = -H or -F, R3 = -H, or R2 and R3 together represent -CH2-CH2-, R4 = -H or -OCH3, R5 = -H, -OCH3 or...  
WO/2006/029532A1
Nitrate esters and methods for mitigating neurodegeneration, affecting neuroprotection, affecting cognition enhancement, and/or preventing or mitigating tissue and/or cellular damage in a subject are described. Neurological or cognitive ...  
WO/2006/024402A1
The invention relates to novel salts of chiral 3-halophthalic acid derivatives of formula (I) from 3-halophthalic acid anhydrides of formula (II), amines of formula (III), a method for the production thereof, the use thereof for producin...  
WO2005060692A3
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.  
WO/2006/024412A2
Novel optically active phthalamides of the formula (I) in which A, q, R1, R2, E1, E2, X, m, Y, n and Z are as defined in the description, processes for preparing these compounds and their use for controlling pests.  
WO/2006/021806A1
Compounds of formula (I) are useful in treatment of sleep disorders and other conditions mediated by 5-HT2A receptor activity.  
WO/2006/021759A1
The invention relates to substituted phenoxyacetic acids of formula (I), where the variables are as defined in claim 1, as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, a...  
WO2004110364A3  
WO/2006/021805A1
Compounds of formula (I) are potent and selective antagonists of the human 5-HT2A receptor, and hence useful in treatment of a variety of adverse conditions of the CNS.  
WO/2006/021743A1
A process for selectively controlling the crystallisation of thermodynamically stable Form (1) or kinetically stable Form (2) polymorphs of mesotrione from an aqueous mesotrione solution, said method comprising adjusting the pH of the me...  
WO/2006/023778A2
The invention relates to small molecules which function as inhibitors of anti-apoptotic Bcl-2 family member proteins (e.g., Bcl-2 and Bcl-xL). The invention also relates to the use of these compounds for inducing apoptotic cell death and...  
WO/2006/022225A1
An optically active phthalamide derivative represented by the general formula (I): (wherein R1 and R2 each represents H or optionally substituted C1-6 alkyl or C1-6 alkoxycarbonyl; R3 represents C1-6 alkyl; A represents H, C1-6 alkyl, C3...  
WO2005110980A3
Aryl sulfone compounds of formula (I) and (II) are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders.  
WO/2006/015829A1
Compounds of formula (I), a pharmaceutically acceptable salt, solvate or prodrug thereof are disclosed: wherein R1 is C1-6alkyl, haloC1-6alkyl, C2-6alkenyl, amino, monoC1-4alkylamino or diC1 4alkylamino; R2 and R3, which may be the same ...  
WO2004101752A3
Novel acyl urea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthriti...  
WO/2006/016194A1
Compounds of Formula (I) wherein R1 is a cycloalkylsulphonyl group, or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.  
WO/2006/013085A1
The invention relates to compounds of formula (I), in which R, R' and R' are as defined in the disclosure and the pharmaceutically acceptable esters thereof. The compounds of the invention reduce the synthesis of kynurenic acid thus inhi...  
WO/2006/013193A2
Described herein are derivatives of arylsulfonamido-substituted hydroxamic acid of formula (I) having good solubility in water and inhibitory activity of matrix metalloproteinases, useful for the preparation of pharmaceutical composition...  
WO/2006/012227A2
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor MR, and pharmaceutical compositions thereof. The compounds of the invention can be useful in the tr...  
WO/2006/011669A1
Novel cinnamic acid-related compounds and salts thereof which are useful as drugs, specifically, compounds represented by the general formula [1] and salts thereof: [1] wherein A is a six-membered hydrocarbon ring or a six-membered heter...  
WO/2006/011469A1
A cyclohexane derivative having the function of reducing a blood sugar level and having preferable properties required of medicines, such as long-lasting drug activity, metabolic stability, and safety; and a medicinal composition for use...  
WO/2006/011466A1
Disclosed are a compound and pharmaceutically acceptable salts thereof represented by the general formula (1) below. (In the formula (1), R1, R2, R3, R4 and X are the same as R1, R2, R3, R4 and X defined in the description.)  
WO2005037205A3
The present invention relates to a novel class of anti-cancer compounds, which contain a haloacetamide or azide moiety and are, in one embodiment, alkylating agents. These agents, either alone or in a composition, are useful for treating...  
WO/2006/009134A1
A novel fungicide that exhibits a wide disease control spectrum against pathogenic fungi acting on various crops and helps resolve worsening resistant strain problems. There are provided diamine derivatives of the formula (1), a process ...  
WO2005066119A3
Novel florfenicol compounds having the chemical structure: Or a pharmaceutically-acceptable salt thereof or a solvate thereof,or prodrug thereof, wherein R1 is CHCl2, CHClF, CHF2, CHBrCl, CH3, CH2N3, CH2CN, CH(R2)NH2 or CH X1X2; where R2...  
WO/2006/005909A1
The invention relates to substituted acids of formula (I), where T,W,X,Y,Z,R1 and R2 as defined in the claims, as useful pharmaceutical compounds for treating asthma and rhinitis, pharmaceutical compositions containing them, and a proces...  
WO/2006/006736A1
A method of crystallizing bicalutamide, comprising adding an acetone solution containing bicalutamide to water. There is provided a crystal of bicalutamide obtained by the above method and having a particle size distribution of Dp10=1 to...  
WO/2006/003923A1
Disclosed is an excellent LXR modulator. Specifically disclosed are compounds represented by the following general formula (I). (In the formula, R1 represents -COR9 (wherein R9 represents an alkyl, an optionally substituted alkoxy or an ...  
WO/2005/123667A1
Compounds of formula (I) wherein the substituents are as defined in claim 1, are suitable for use as herbicides.  
WO2005077122A3
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).  
WO/2005/121078A2
The invention relates to substituted cyclopentene compounds of general formula (I), to a method for the production thereof, medicaments containing said compounds, in addition to the use thereof in the production of medicaments.  
WO/2005/121077A1
This invention provides a general method for the synthesis of polymer-supported benzoquinones described by the following generic structure I: wherein: •, X, R1, R2 and R3 are described in the main text. The general concept of the metho...  
WO/2005/119315A2
In one aspect, the present invention provides a hyperpolarizable organic chromophore. The chromophore is a nonlinear optically active compound that includes a &pgr -donor conjugated to a &pgr -acceptor through a &pgr -electron conjugated...  
WO/2005/118530A1
Disclosed are novel triketone compounds, a method for producing those, and an excellent herbicide containing those. Specifically disclosed are triketone compound represented by the formula (I) below or salts thereof. (I) [In the formula,...  
WO/2005/113491A1
A monomer comprising the structure (1a) or (1b) wherein Z comprises S, SO2, or POR wherein R comprises a linear or branched perfluoroalkyl group of 1 to 14 carbon atoms optionally containing oxygen or chlorine, an aryl or substituted ary...  
WO/2005/113506A1
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated R...  
WO/2005/110981A1
The present invention relates to a compound formula[I]: wherein X is bond or -O-, R1 is formula[A] or formula [B] in which R5, R6 and R7 are each as defined in the description, R2 is hydrogen or lower alkyl, R3 is hydrogen or an amino pr...  
WO2005090296A3
The invention provides N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula (I), wherein R1, R2, R3, R4, and R3, are...  
WO/2005/110980A2
Aryl sulfone compounds of formula (I) and (II) are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders.  
WO/2005/110955A1
The invention provides reagents and kits for introducing a fixed charge to the side-chain of methionine, and peptides and proteins containing methionine, for selective identification by tandem mass spectrometry. The reagents are based on...  
WO/2005/105718A2
The present invention relates to a process for the preparation of compounds of formula (I), wherein the substituents are as defined in claim 1, by reacting a compound of formula (II), with a bromine or chlorine source to form a compound ...  
WO/2005/105717A1
The present invention relates to the preparation of compounds of formula (I); wherein the substituents are as defined in claim 1, by reacting a compound of formula (II); with a bromine or chlorine source to form a compound of formula (II...  
WO/2005/105764A1
Compounds of the formula (I): in which R, R1 and R2 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and . processes for the...  
WO/2005/105712A1
Novel sulfon amide derivatives are chemical uncouplers useful e.g. for the treatment of obesity.  
WO2005079700A3
The present invention relates to methods of using fluorosulfones for i) extinguishing fire by applying to the fire such a fluorosulfone, ii) preventing fire in an air-containing enclosed area containing combustible materials by introduci...  

Matches 751 - 800 out of 10,878