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Matches 51 - 100 out of 10,644

Document Document Title
WO/2017/023912A1
Compounds according to Formula (I) are provided and salts thereof, wherein R1, R2, R 3 , R4, R5, R6, R13, A, X and Y are as defined herein. Methods for preparing compounds of Formula (I) are also provided, as well as methods of treating ...  
WO/2017/023192A1
The invention relates to a group of novel extractants for extracting nitric acid from aqueous solutions, inter alia, wastewater, which extractants can be used for the liquid-liquid extraction of nitric acid and the separation of hydrochl...  
WO/2017/014214A1
A compound represented by formula (4) can be produced by adding a heterogeneous transition metal catalyst to a solution containing a compound represented by formula (3) and then subjecting the resultant mixture to a reduction reaction, w...  
WO/2017/013375A1
The invention relates to a process for preparing ionomers of unipolar cationic conductivity from fluorine-containing ionic monomers, to said ionomers of unipolar cationic conductivity, to their uses, to an electrolytic composition compri...  
WO/2017/010399A1
Provided are compounds having RORγt inhibitory effects represented by formula (I). Compounds represented by formula (I) (wherein L represents -NR1ACO-, -SO2- or the like, A represents a substituted or unsubstituted aromatic carbocyclic ...  
WO/2016/205707A1
Disclosed herein are novel cannabionid receptor-2 (CB2) agonists and inverse agonists represented by Formula (I), and method of modulating the activity of CB2 by contacting the CB-2 receptor with a compound of Formula (I). Also, disclose...  
WO/2016/197900A1
A process for the preparation of mesotrione enolate is provided, the process comprising providing a solution of mesotrione in an organic solvent and contacting the solution with a moderate base in the presence of water at a pH of from 6 ...  
WO/2016/198374A1
Substituted aromatic sulfonamides of formula (I) pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a di...  
WO/2016/201039A1
A process for preparing diaryl sulfones, such as 4,4'-dichlorodiphenylsulfone is disclosed. The process comprises contacting an aryl compound with sulfur trioxide to provide a benzene sulfonic acid. The benzene sulfonic acid is coupled t...  
WO/2016/191872A1
Methods and compositions are provided for the treatment of familial exudative vitreoretinopathy (FEVR) through the administration of a therapeutically effective amount of a sphingosine-1-phosphate receptor type 2 (S1PR2) antagonist. Also...  
WO/2016/193452A1
The present invention relates to compounds according to Formula I: or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORy and are useful for the treatment of RORy mediated diseases.  
WO/2016/193470A1
The present invention relates to compounds according to Formula (I): or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORy and are useful for the treatment of RORy mediated diseases.  
WO/2016/192694A1
The invention relates to a preparation method of (S)-l-(3-ethoxy-4-methoxyphenyl)- 2-(methylsulfonyl)-ethyl-amine (S)-l, or its N-acyl derivatives of general formula (S)-2. The amine (S)-l is the key intermediate in the synthesis of (S)-...  
WO/2016/194929A1
Compounds shown by formula (3): (in the formula, R1 represents a C1-C6 perfluoroalkyl group, R2 represents a C1-C6 alkyl group, and m represents any integer of 0-3) or salts thereof which are useful as production intermediates of pharmac...  
WO/2016/196664A1
The invention provides methods and agents that modulate RelA activity. These methods and modulators of RelA acitivity can be used to treat cancer progression of basal-like breast cancer, such as triple-negative breast cancer.  
WO/2016/196591A1
Small molecule compounds derived from α-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB,...  
WO/2016/193459A1
The present invention relates to compounds according to Formula I: or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORy and are useful for the treatment of RORy mediated diseases such as autoimmu...  
WO/2016/193461A1
The present invention relates to novel compounds according to Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORγ and are useful for the treatment of RORγ mediated diseases.  
WO/2016/189486A1
The present invention provides an improved process for preparation of an intermediate of apremilast. The present invention also provides an improved process for preparation of apremilast. This invention also provides novel polymorphs of ...  
WO/2016/182021A1
 In the production of produce, such as agriculture and horticulture, damage caused by disease and the like is greater than ever, and there is a need for the development of a novel horticultural fungicide due to factors such as the outb...  
WO/2016/182036A1
The present invention provides compounds having a Toll-like receptor 4 (TLR4) signaling inhibitory action useful as preventive and therapeutic drugs of inflammatory disease and/or central nervous system disease or diseases such as chemot...  
WO/2016/175128A1
The present invention relates to a process for producing an allyl-substituted bisphenol compound, the process including a step in which a diallyl-etherified bisphenol compound represented by general formula (I) is caused to undergo therm...  
WO/2016/173020A1
A conjugated compound containing a diphenyl sulfone phenyl structure, a method for preparing same, and use for fabricating a light emitting layer or an electronic transmission layer of an organic electroluminescent diode. The compound ha...  
WO/2016/174685A1
A process for the resolution of racemic 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylami ne using novel chiral salts is disclosed. An L-phenylalanine p-toluene-sulfonamide salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsul...  
WO/2016/168059A1
This disclosure relates to the field of moiecuies having pesticida i utility against pests in Phyla Arthropoda, Moliusca, and hJematoda, processes to produce such moiecuies, intermediates used In such processes, pesticidai compositions c...  
WO/2016/168058A1
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...  
WO/2016/161996A1
The present invention provides a method of chiral resolution of racemic amines of the benzyl type by means of salts formed with tartaric acid of formula (3) and intermediate of formula (2), and their use in the synthesis of Apremilast of...  
WO/2016/146607A1
The invention relates to a novel and improved method for producing (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo -1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I), and to the produc...  
WO/2016/145236A1
Chemical compounds that modulate HIF-2α activity, their polymorphs, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with HIF-2α, are described herein.  
WO/2016/144825A1
Aromatic entities that modulate HIF-2α activity, pharmaceutical compositions containing the aromatic entities, and methods of using these chemical entities for treating proliferative diseases and conditions associated with HIF-2α activ...  
WO/2016/122287A1
The present description relates to a compound comprising an aromatic ring, a polymer electrolyte membrane comprising same, a membrane electrode assembly comprising the polymer electrolyte membrane, a fuel cell comprising the membrane ele...  
WO/2016/119643A1
Disclosed are a compound as shown by the following formula 1, and a pharmaceutically acceptable salt, an ester, a hydrate and an organic solvate thereof. In the formula (1), the groups R1 to R17 are independently selected from the group ...  
WO/2016/099050A1
The present specification relates to a novel compound, a polymer electrolyte membrane comprising same, a membrane-electrode assembly comprising the polymer electrolyte membrane, a fuel cell comprising the membrane-electrode assembly, and...  
WO/2016/086710A1
Disclosed is a carboxylic acid preparation method. The method is characterized in that: a compound (II) reacts in the presence of hydrogen peroxide and a base to produce a target product (I) represented by the following equation: R1 is a...  
WO/2016/076160A1
[Problem] To provide a method for producing an industrially preferred optically active sulfoxide derivative. [Solution] A method for producing an optically active sulfoxide derivative represented by general formula (1), the method charac...  
WO/2016/071088A1
A poly(arylether sulfone)polymer[(t-PAES)polymer], wherein more than 70% moles of the recurring units are recurring units (Rt) of formula (St): -E-Ar1-SO2-[Ar2-(T-Ar3)n-SO2]m-Ar4- (formula St) wherein: n and m, equal to or different from...  
WO/2016/069358A1
A synthesis process for making a benzoxazine compound containing at least one benzoxazine unit from aromatic amine containing at least one primary amino group, at least one phenolic compound with at least one ortho-hydrogen, and alkyl fo...  
WO/2016/066574A1
Disclosed are compounds of formula (I) which possess anthelminthic properties wherein the structural elements have the meaning as indicated in the description. Further disclosed are such compounds for the control, treatment and/or preven...  
WO/2016/068605A1
The present description relates to a fluorine-based compound for a brancher, polymer using same, a polymer electrolyte membrane using same, a fuel cell using same, and a redox flow battery comprising same.  
WO/2016/062597A1
The present invention relates to a method for the manufacture of a poly(aryl ether) such as a poly(aryl ethersulfone) or a poly(aryl ether ketone) including the use of an organic base having a pKa of at least 10.  
WO/2016/058082A1
Compounds having a structure of Formula I: (I) or a pharmaceutically acceptable salt or stereoisomer thereof, wherein R1, R2, R3, R4, Z, X and n are as defined herein, and wherein the compound comprises at least one 18F moiety, are provi...  
WO/2016/044331A1
Disclosed herein are compounds of Formulae (I) and (II), methods of synthesizing compounds of Formulae (I) and (II), and methods of using compounds of Formulae (I) and (II) as an analgesic.  
WO/2016/039691A1
Compounds of formula (I): wherein R and A- are defined herein as a catalyst for making chiral heterocyclic sulfoxides and a method of producing enantioenriched sulfoxide in the presence of the said compounds.  
WO/2016/032120A1
The present invention relates to: a novel amino-phenyl-sulfonyl-acetate derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating diabetes, containing the same as an active ingr...  
WO/2016/031831A1
In order to achieve excellent mechanical strength of cured products, and excellent handling properties at low viscosity even in a room temperature environment, a polymerizable monomer represented by general formula (1) is provided, as we...  
WO/2016/028959A1
Disclosed are compounds of Formulas (I), (II), (III), (IV), and (V) and/or a salt thereof, wherein R1 is OH or OP(O)(OH)2, and X1, X2, X3, R2, R2a, Ra, Rb, and Rc are defined herein. Also disclosed are methods of using such compounds as ...  
WO/2016/024434A1
The present invention relates to the following: a compound represented by formula [1] or a salt thereof; a fungicidal composition comprising the compound or salt thereof; a method for eliminating plant diseases brought on by plant pathog...  
WO/2016/013633A1
A compound represented by formula (I) or a salt thereof has an excellent noxious organism control activity, particularly an excellent miticidal activity and/or an excellent insecticidal activity, is highly safe, and can be synthesized in...  
WO/2016/005318A1
The present invention provides novel amino lipids and a method for synthesizing these compounds. According to the invention, the amino lipids have a structure of the following formula (I) wherein Z is either hydrogen or -X1 R1, R1 and R2...  
WO/2016/001073A1
The invention relates to benzoic acid amides of general formula (I) as herbicides. In formula (I) X, Z and R represent radicals such as alkyl and cycloalkyl. Q represents a 5-membered heterocycle.  

Matches 51 - 100 out of 10,644