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Matches 151 - 200 out of 10,857

Document Document Title
WO/2016/146607A1
The invention relates to a novel and improved method for producing (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo -1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I), and to the produc...  
WO/2016/145236A1
Chemical compounds that modulate HIF-2α activity, their polymorphs, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with HIF-2α, are described herein.  
WO/2016/144825A1
Aromatic entities that modulate HIF-2α activity, pharmaceutical compositions containing the aromatic entities, and methods of using these chemical entities for treating proliferative diseases and conditions associated with HIF-2α activ...  
WO/2016/122287A1
The present description relates to a compound comprising an aromatic ring, a polymer electrolyte membrane comprising same, a membrane electrode assembly comprising the polymer electrolyte membrane, a fuel cell comprising the membrane ele...  
WO/2016/119643A1
Disclosed are a compound as shown by the following formula 1, and a pharmaceutically acceptable salt, an ester, a hydrate and an organic solvate thereof. In the formula (1), the groups R1 to R17 are independently selected from the group ...  
WO/2016/099050A1
The present specification relates to a novel compound, a polymer electrolyte membrane comprising same, a membrane-electrode assembly comprising the polymer electrolyte membrane, a fuel cell comprising the membrane-electrode assembly, and...  
WO/2016/086710A1
Disclosed is a carboxylic acid preparation method. The method is characterized in that: a compound (II) reacts in the presence of hydrogen peroxide and a base to produce a target product (I) represented by the following equation: R1 is a...  
WO/2016/076160A1
[Problem] To provide a method for producing an industrially preferred optically active sulfoxide derivative. [Solution] A method for producing an optically active sulfoxide derivative represented by general formula (1), the method charac...  
WO/2016/071088A1
A poly(arylether sulfone)polymer[(t-PAES)polymer], wherein more than 70% moles of the recurring units are recurring units (Rt) of formula (St): -E-Ar1-SO2-[Ar2-(T-Ar3)n-SO2]m-Ar4- (formula St) wherein: n and m, equal to or different from...  
WO/2016/069358A1
A synthesis process for making a benzoxazine compound containing at least one benzoxazine unit from aromatic amine containing at least one primary amino group, at least one phenolic compound with at least one ortho-hydrogen, and alkyl fo...  
WO/2016/066574A1
Disclosed are compounds of formula (I) which possess anthelminthic properties wherein the structural elements have the meaning as indicated in the description. Further disclosed are such compounds for the control, treatment and/or preven...  
WO/2016/068605A1
The present description relates to a fluorine-based compound for a brancher, polymer using same, a polymer electrolyte membrane using same, a fuel cell using same, and a redox flow battery comprising same.  
WO/2016/062597A1
The present invention relates to a method for the manufacture of a poly(aryl ether) such as a poly(aryl ethersulfone) or a poly(aryl ether ketone) including the use of an organic base having a pKa of at least 10.  
WO/2016/058082A1
Compounds having a structure of Formula I: (I) or a pharmaceutically acceptable salt or stereoisomer thereof, wherein R1, R2, R3, R4, Z, X and n are as defined herein, and wherein the compound comprises at least one 18F moiety, are provi...  
WO/2016/044331A1
Disclosed herein are compounds of Formulae (I) and (II), methods of synthesizing compounds of Formulae (I) and (II), and methods of using compounds of Formulae (I) and (II) as an analgesic.  
WO/2016/039691A1
Compounds of formula (I): wherein R and A- are defined herein as a catalyst for making chiral heterocyclic sulfoxides and a method of producing enantioenriched sulfoxide in the presence of the said compounds.  
WO/2016/032120A1
The present invention relates to: a novel amino-phenyl-sulfonyl-acetate derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating diabetes, containing the same as an active ingr...  
WO/2016/031831A1
In order to achieve excellent mechanical strength of cured products, and excellent handling properties at low viscosity even in a room temperature environment, a polymerizable monomer represented by general formula (1) is provided, as we...  
WO/2016/028959A1
Disclosed are compounds of Formulas (I), (II), (III), (IV), and (V) and/or a salt thereof, wherein R1 is OH or OP(O)(OH)2, and X1, X2, X3, R2, R2a, Ra, Rb, and Rc are defined herein. Also disclosed are methods of using such compounds as ...  
WO/2016/024434A1
The present invention relates to the following: a compound represented by formula [1] or a salt thereof; a fungicidal composition comprising the compound or salt thereof; a method for eliminating plant diseases brought on by plant pathog...  
WO/2016/013633A1
A compound represented by formula (I) or a salt thereof has an excellent noxious organism control activity, particularly an excellent miticidal activity and/or an excellent insecticidal activity, is highly safe, and can be synthesized in...  
WO/2016/005318A1
The present invention provides novel amino lipids and a method for synthesizing these compounds. According to the invention, the amino lipids have a structure of the following formula (I) wherein Z is either hydrogen or -X1 R1, R1 and R2...  
WO/2016/001073A1
The invention relates to benzoic acid amides of general formula (I) as herbicides. In formula (I) X, Z and R represent radicals such as alkyl and cycloalkyl. Q represents a 5-membered heterocycle.  
WO/2016/001075A1
The invention relates to N-(1-methyltetrazol-5-yl)benzoic acid amides of the general formula (I) as herbicides. In formula (I) X, Z and R represent radicals such as alkyl and cycloalkyl.  
WO/2016/001390A1
The present invention relates to a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof Formula (I), and its uses to treat a disorder associated with protein misfolding stress and in particular with an...  
WO/2016/001074A1
The invention relates to benzoic acid amides of general formula (I) as herbicides. In formula (I) X, Z and R represent radicals such as alkyl and cycloalkyl. Q represents a 5-membered heterocycle.  
WO/2015/198850A1
Provided is a method for producing a compound represented by formula (2-b), which is useful as an intermediate for producing agricultural chemicals. The method includes a step for obtaining a compound represented by formula (2-a) by oxid...  
WO/2015/194293A1
This lubricant contains a protic ionic liquid having a conjugate acid (B+) and a conjugate base (X-), the ionic liquid is represented by general formula (1), and the conjugate base is one of the conjugate base of sulfonic acid, the conju...  
WO/2015/181249A1
The present invention relates to processes for preparing β-aminosulfone compounds. The provided compounds are useful intermediates in the preparation of sulfone group containing isoindoline-based compounds, in particular apremilast.  
WO/2015/026990A8
The present disclosure is generally directed to compositions and methods for treating diseases that are ameliorated by the inhibition of CYP26 mediated retinoic acid metabolism. The compositions comprise compounds of formula (I). A repre...  
WO/2015/157927A1
Disclosed is a new florfenicol synthesizing method. The method synthesizes florfenicol products meeting requirements of the Drug Administration by a series of combinations of cyclization, selective reduction, fluorinated open ring, depro...  
WO/2015/157313A1
Described herein, inter alia, are compositions and methods useful for inhibiting fatty acid amide hydrolase.  
WO/2015/145371A1
The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparati...  
WO/2011/088209A3
This present disclosure is directed to novel prodrugs of activated vitamin D3 compounds. The prodrugs can be designed to have one or more beneficial properties, such as selective inhibition of the enzyme CYP24, low calcemic activity, and...  
WO/2015/131200A1
Small molecule xanthine oxidase inhibitors, speifically substituted benzaldehydes including dihydroxy and trihydroxy benzaldehydes having therapeutic utility in the treatment of gout and hyperuricemia are provided. Pharmaceutical composi...  
WO/2015/013187A8
The present invention relates to hydroxamate compounds and pharmaceutical compositions that are useful for treating and/or preventing metabolic inflammation mediated diseases such as diabetes, obesity, hypertension, dyslipidemia, a neuro...  
WO/2015/104343A1
It relates to spirocyclic compounds of formula (I), or pharmaceutically or veterinary acceptable salts thereof, or any stereoisomers either of the compounds of formula (I) or of their pharmaceutically or veterinary acceptable salts, wher...  
WO/2015/066135A3
Metal ligand-containing prepolymers, compositions containing metal ligand-containing prepolymers, methods of synthesizing metal ligand-containing prepolymers and the use of metal ligand-containing prepolymers in aerospace sealant applica...  
WO/2015/103507A1
Described are RORϒ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions ...  
WO/2015/103508A1
Described are RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions ...  
WO/2015/100225A1
The present invention provides sulfur- or selenium-containing compounds comprising hydrophobic moieties and ethoxylated ester or ethoxylated amide moieties such that the compounds have surfactant properties. Also provided are methods for...  
WO/2015/096226A1
A thermally activated delayed fluorescence material, synthetic process thereof and OLED device using same. The structure of the thermal activation delayed fluorescence material is represented by formula (1), wherein Ar1 is the same as or...  
WO/2015/087352A1
The present patent discloses a novel, efficient and transition-metal-free room temperature single step process for synthesis of aryl sulfones and substituted aryl sulfones starting from aryl substrates.  
WO/2015/087834A1
The objective of the present invention is to provide a polyester resin composition which is free from the generation of an irritating gas in the production processes, and which is not increased in the viscosity of a polyester resin even ...  
WO/2015/082533A1
The present invention relates to compounds according to Formula I: Wherein: A11 - A14 are N or CR11, CR12, CR13, CR14, respectively, with the proviso that no more than two of the four positions A can be simultaneously N; R1 is C(1-6)alky...  
WO/2015/078802A1
The present invention relates to compounds of general formula (I), wherein the groups R1, R2, R3, X, m and n are defined as in claim 1, wich have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate ...  
WO/2015/081188A1
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an omega-(arylsulfonyl)alkylnitrile compound, or a pharmaceutically acceptable salt thereof. The present invention is ...  
WO/2015/080217A1
A purpose of the present invention is to provide a coloring resin composition which has high color purity and satisfactory light resistance, and which develops a high contrast. Another purpose of the present invention is to provide: a co...  
WO/2015/076395A1
The present invention addresses the problem of providing: an acid- and radical-generating agent which has high sensitivity to an active energy ray having a wavelength of about 300 to 450 nm, can exhibit both high acid-generating ability ...  
WO/2015/074281A1
The present application relates to rigosertib salt and a crystal form thereof. Compared with existing rigosertib salt, the rigosertib salt and the crystal form thereof in the present application has advantages on crystallinity, crystal h...  

Matches 151 - 200 out of 10,857