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Patent Searching and Data


Matches 351 - 400 out of 10,857

Document Document Title
WO/2012/011125A1
The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are therefore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for thei...  
WO/2012/007644A1
The invention relates to novel arylamide derivatives having formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, where R1 - R11, R', R", z and X are as defined in the claims. The arylamide derivatives of formula (...  
WO/2012/008435A1
Disclosed is a novel biaryl amide derivative represented by formula (1) and having an affinity for the aldosterone receptor; also disclosed is a pharmaceutically acceptable salt thereof. (In the formula, A is any of the groups represente...  
WO/2012/005229A1
Disclosed is a compound which is represented by general formula (I) and has an inhibitory effect on ADAM17, a salt thereof, or a solvate thereof. In formula (I), X represents a phenylene group, Y represents a hydrogen atom, -(CH2)mR1, or...  
WO/2012/004443A1
The invention relates to compounds which are active pharmaceutical principles used for treating and/or preventing inflammation and/or cancer, having formula (I) in which -X- is a single bond, -NH- or -CO-, and -Ar is an aromatic radical ...  
WO/2011/012247A8
Described are 2-(3-alkylthiobenzoyl)cyclohexanediones of the general formula (I) as herbicides. X, Y, R1 to R8 in this formula (I) stand for radicals such as hydrogen or organic radicals such as alkyl and alkoxy.  
WO/2011/161101A1
The invention relates to selective estrogen receptor modulators (SERMs) and to processes for production thereof, to the use thereof for treatment and/or prophylaxis of disorders, and to the use thereof for production of medicaments for t...  
WO/2011/158918A1
Disclosed is a novel polynuclear metal compound which is specific, has high catalytic properties, and has great potential as a novel functional material or the like. Specifically disclosed is a polynuclear metal compound which has at lea...  
WO/2011/154677A1
The present invention provides compounds of formula (I) in which, n, R1, R2 and Q are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.  
WO/2011/117324A3
A new process for making polyprenols is described as well as the use of these building blocks in the synthesis of Vitamin K2. The process involves reaction of a compound of formula (X) with a compound of formula (XI) in the presence of a...  
WO/2011/067649A3
The present invention provides a method for the preparation of polymer grade 4,4'-dichlorodiphenyl sulfone in steps comprising reacting dimethyl sulfate and sulfur trioxide optionally containing a catalyst; reacting the formed dimethyl p...  
WO/2011/131542A1
The invention relates to a method for producing products, characterized in that (A) at least one compound of general formula (I), where R1 is selected from hydrogen and C1-C4-alkyl, and a sulfonating agent are reacted with one another at...  
WO/2011/132171A1
The present invention relates to nitric oxide releasing prodrugs of known drugs or therapeutic agents which are represented herein as compounds of formula (I) wherein the drugs or therapeutic agents contain one or more functional groups ...  
WO/2011/131665A1
The invention relates to a method for producing 4,4'-dichlorodiphenyl sulfone from monochlorobenzene in which the maximum concentration of hydrocarbons containing 5 to 8 carbon atoms is 100 ppm relative to the total weight of the monochl...  
WO/2011/131508A1
The invention relates to a method for producing 4,4'-dichlorodiphenyl sulfone, comprising the reaction of monochlorobenzene with liquid sulfur trioxide that has a maximum boron concentration of 100 ppm relative to the total weight of the...  
WO/2011/129967A2
The description includes materials that may be useful for fuel cell applications such as in the manufacture of fuel cell electrodes, proton exchange membranes (PEM), as catalyst additives or in tie layers designed to be thermally and che...  
WO/2011/126099A1
A medication that has excellent agonist effects on CaSR and enables the prevention or treatment of diabetes or obesity is provided by means of compound represented by formula (I) defined in the description, or a composition comprising a ...  
WO/2011/107465A1
The invention relates to a method for producing 4-chlorobenzene sulphonic acid from 2-chlorobenzene sulphonic acid and/or 3-chlorobenzene sulphonic acid, comprising the reaction of 2-chlorobenzene sulphonic acid and/or 3-chlorobenzene su...  
WO/2011/101321A1
A description is given of 3-aminocarbonyl-substituted benzoylcyclo¬≠hexanediones of the general formula (I) as herbicides. In this formula (I), R1 to R5 stand for radicals such as hydrogen, organic radicals such as alkyl, and other radic...  
WO/2011/102514A1
A compound represented by formula (I) [wherein each symbol is as defined in the description], a salt thereof, or a prodrug of the compound or the salt, which has an excellent inhibitory activity on long chain fatty acids family member 6 ...  
WO/2011/098985A1
The invention relates to compounds of formula (Formula III) (III) and of formula (Formula (IV) (IV), to methods for producing said compounds, and to the use thereof in the synthesis of saxagliptin.  
WO/2011/099572A1
Provided is a fluoroalkane derivative represented by general formula (1): R-SO2-Ar-O-R1 (1) wherein Ar represents a substituted or unsubstituted divalent aromatic group having 8-30 nuclear atoms; R1 represents a saturated or unsaturated ...  
WO/2011/093423A1
Disclosed is a method for producing a compound represented by formula (E)-I characterized by comprising precipitating crystals of the compound represented by formula (E)-I in the coexistence of an acid and shifting the equilibrium of the...  
WO/2011/088209A2
This present disclosure is directed to novel prodrugs of activated vitamin D3 compounds. The prodrugs can be designed to have one or more beneficial properties, such as selective inhibition of the enzyme CYP24, low calcemic activity, and...  
WO/2011/088015A1
Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are ...  
WO/2011/073143A1
Substituted cyanobutyrates of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts...  
WO/2011/073473A1
Vinyl sulphone functionalised lipid systems. Synthesis and uses. Compound comprising a molecule of lipid nature and a vinyl sulphone group permitting the realisation of lipidation of biomolecules in a highly efficacious and simple manner...  
WO/2011/018445A3
The present invention relates to a process for the preparation of (R)-2-phenyl propionic acid derivatives of the formula (I), wherein R1 is C1-6-alkyl and R2 is hydrogen or halogen, or of a salt thereof by asymmetric hydrogenation of the...  
WO/2011/045703A3
The present invention is directed to a new class of alpha - alkylsulfonyl hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.  
WO/2011/044506A3
The invention provides sulphone compounds according to formula (Ia) and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various sulphone compounds are provided. The compounds ar...  
WO/2011/058918A1
Disclosed is a compound represented by formula (I) [wherein Ra and Rb independently represent an organic group which has 1 to 30 carbon atoms and may have a substituent; X1 and X2 independently represent a hydrogen atom, a halogen atom, ...  
WO/2011/059042A1
Disclosed is a compound represented by formula (I) (wherein the symbols are as defined in the description) or a salt thereof, which exhibits excellent long chain fatty acid elongase 6 inhibitory activity and is useful for prevention and ...  
WO/2011/059731A1
The present invention is directed to novel alkynyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1.  
WO/2011/055381A1
The invention relates to the removal of the impact-sensitive and hazardous sodium azide (NaN3) salt along with ammonium chloride (NH4Cl) for the recovery of dimethyl sulfoxide (DMSO) solvent present in a pharmaceutical industrial effluen...  
WO/2009/072002A3
The present invention generally relates to anticancer agents and methods of treating cancer. The anticancer agents described herein comprise a bisphenol core and generally act as topoisomerase II inhibitors, though their anticancer activ...  
WO/2011/008543A3
Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated...  
WO/2011/045703A2
The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.  
WO/2011/043456A1
Disclosed is a compound represented by formula (I) or the like, which has a PAI-1 inhibitory effect. (In the formula, R1 represents an optionally substituted C6-10 aryl group or the like; R2 represents an optionally substituted C6-10 ary...  
WO/2009/149806A3
The invention relates to 4-(3-alkyl sulfinyl benzoyl) pyrazoles of the general formula (I) as herbicides. In said formula (I), R1 through R4, X, and Y stand for radicals such as hydrogen, organic radicals such as alkyls, and other radica...  
WO/2011/044506A2
The invention provides sulphone compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various sulphone compounds are provided. The compounds are contemplated to have act...  
WO/2010/035000A8
Using a combination of Kumada, Suzuki and Biellmann chemistry, various menaquinones can synthesised rapidly and with stereochemical integrity offering a new way of preparing these vitamin K2 components for the pharmaceutical market. In o...  
WO/2011/039994A1
Disclosed are: a recoding material which has excellent color developing characteristics and excellent storage stability of background and images; and a compound used for the recording material. Specifically disclosed are: a compound repr...  
WO/2011/035875A1
3-Amino-2-nitro-substituted benzoyl derivatives of the general formula (I) are described. In this formula (I), X, R1, R2, R3, R4, R5, R6, R7 and R8 stand for radicals such as hydrogen, organic radicals such as alkyl, and other radicals s...  
WO/2011/035159A1
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity, are disclosed. Specifically, a series of compounds contai...  
WO/2011/034078A1
Disclosed is a compound which is useful as the active ingredient of a medicinal composition, in particular, a medicinal composition for preventing and/or treating a VAP-1 associated disease. As the results of intensive studies on compoun...  
WO/2011/027888A1
Disclosed are a diamide-phenyl derivative which inhibits soluble epoxy hydrolase (sEH), and a pharmaceutically acceptable salt of the diamide-phenyl derivative. Specifically disclosed are a compound represented by formula (I), and a phar...  
WO/2011/019076A1
A process for the preparation of (fluoroalkylthio)acetic acid esters represented by general formula (3) (wherein R is a hydrogen atom or a C1-5 alkyl group; R1 is a C1-4 alkyl group; and R2 is a C1-5 fluoroalkyl group), characterized by ...  
WO/2011/016018A1
The invention relates to a crystalline polymorph Form 3 of 2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione. A process for its preparation, use thereof for the control of weeds, and an herbicidal composition comprising thereof ...  
WO/2011/012815A1
The present invention relates to the masking of the odour of organic sulphides and more particularly that of alkyl sulphides or of dialkyl sulphides, especially dimethyl sulphide, and also of oxides thereof, and especially of dimethyl su...  
WO/2011/012820A1
The invention relates to solvent compositions predominantly comprising at least one oxide of an organic sulfide, more particularly dimethyl sulfoxide, to which is added at least one odour-masking agent comprising at least one compound se...  

Matches 351 - 400 out of 10,857