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Patent Searching and Data


Matches 401 - 450 out of 10,966

Document Document Title
WO/2011/102514A1
A compound represented by formula (I) [wherein each symbol is as defined in the description], a salt thereof, or a prodrug of the compound or the salt, which has an excellent inhibitory activity on long chain fatty acids family member 6 ...  
WO/2011/098985A1
The invention relates to compounds of formula (Formula III) (III) and of formula (Formula (IV) (IV), to methods for producing said compounds, and to the use thereof in the synthesis of saxagliptin.  
WO/2011/099572A1
Provided is a fluoroalkane derivative represented by general formula (1): R-SO2-Ar-O-R1 (1) wherein Ar represents a substituted or unsubstituted divalent aromatic group having 8-30 nuclear atoms; R1 represents a saturated or unsaturated ...  
WO/2011/093423A1
Disclosed is a method for producing a compound represented by formula (E)-I characterized by comprising precipitating crystals of the compound represented by formula (E)-I in the coexistence of an acid and shifting the equilibrium of the...  
WO/2011/088209A2
This present disclosure is directed to novel prodrugs of activated vitamin D3 compounds. The prodrugs can be designed to have one or more beneficial properties, such as selective inhibition of the enzyme CYP24, low calcemic activity, and...  
WO/2011/088015A1
Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are ...  
WO/2011/073143A1
Substituted cyanobutyrates of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts...  
WO/2011/073473A1
Vinyl sulphone functionalised lipid systems. Synthesis and uses. Compound comprising a molecule of lipid nature and a vinyl sulphone group permitting the realisation of lipidation of biomolecules in a highly efficacious and simple manner...  
WO/2011/018445A3
The present invention relates to a process for the preparation of (R)-2-phenyl propionic acid derivatives of the formula (I), wherein R1 is C1-6-alkyl and R2 is hydrogen or halogen, or of a salt thereof by asymmetric hydrogenation of the...  
WO/2011/045703A3
The present invention is directed to a new class of alpha - alkylsulfonyl hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.  
WO/2011/044506A3
The invention provides sulphone compounds according to formula (Ia) and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various sulphone compounds are provided. The compounds ar...  
WO/2011/058918A1
Disclosed is a compound represented by formula (I) [wherein Ra and Rb independently represent an organic group which has 1 to 30 carbon atoms and may have a substituent; X1 and X2 independently represent a hydrogen atom, a halogen atom, ...  
WO/2011/059042A1
Disclosed is a compound represented by formula (I) (wherein the symbols are as defined in the description) or a salt thereof, which exhibits excellent long chain fatty acid elongase 6 inhibitory activity and is useful for prevention and ...  
WO/2011/059731A1
The present invention is directed to novel alkynyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1.  
WO/2011/055381A1
The invention relates to the removal of the impact-sensitive and hazardous sodium azide (NaN3) salt along with ammonium chloride (NH4Cl) for the recovery of dimethyl sulfoxide (DMSO) solvent present in a pharmaceutical industrial effluen...  
WO/2009/072002A3
The present invention generally relates to anticancer agents and methods of treating cancer. The anticancer agents described herein comprise a bisphenol core and generally act as topoisomerase II inhibitors, though their anticancer activ...  
WO/2011/008543A3
Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated...  
WO/2011/045703A2
The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.  
WO/2011/043456A1
Disclosed is a compound represented by formula (I) or the like, which has a PAI-1 inhibitory effect. (In the formula, R1 represents an optionally substituted C6-10 aryl group or the like; R2 represents an optionally substituted C6-10 ary...  
WO/2009/149806A3
The invention relates to 4-(3-alkyl sulfinyl benzoyl) pyrazoles of the general formula (I) as herbicides. In said formula (I), R1 through R4, X, and Y stand for radicals such as hydrogen, organic radicals such as alkyls, and other radica...  
WO/2011/044506A2
The invention provides sulphone compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various sulphone compounds are provided. The compounds are contemplated to have act...  
WO/2010/035000A8
Using a combination of Kumada, Suzuki and Biellmann chemistry, various menaquinones can synthesised rapidly and with stereochemical integrity offering a new way of preparing these vitamin K2 components for the pharmaceutical market. In o...  
WO/2011/039994A1
Disclosed are: a recoding material which has excellent color developing characteristics and excellent storage stability of background and images; and a compound used for the recording material. Specifically disclosed are: a compound repr...  
WO/2011/035875A1
3-Amino-2-nitro-substituted benzoyl derivatives of the general formula (I) are described. In this formula (I), X, R1, R2, R3, R4, R5, R6, R7 and R8 stand for radicals such as hydrogen, organic radicals such as alkyl, and other radicals s...  
WO/2011/035159A1
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity, are disclosed. Specifically, a series of compounds contai...  
WO/2011/034078A1
Disclosed is a compound which is useful as the active ingredient of a medicinal composition, in particular, a medicinal composition for preventing and/or treating a VAP-1 associated disease. As the results of intensive studies on compoun...  
WO/2011/027888A1
Disclosed are a diamide-phenyl derivative which inhibits soluble epoxy hydrolase (sEH), and a pharmaceutically acceptable salt of the diamide-phenyl derivative. Specifically disclosed are a compound represented by formula (I), and a phar...  
WO/2011/019076A1
A process for the preparation of (fluoroalkylthio)acetic acid esters represented by general formula (3) (wherein R is a hydrogen atom or a C1-5 alkyl group; R1 is a C1-4 alkyl group; and R2 is a C1-5 fluoroalkyl group), characterized by ...  
WO/2011/016018A1
The invention relates to a crystalline polymorph Form 3 of 2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione. A process for its preparation, use thereof for the control of weeds, and an herbicidal composition comprising thereof ...  
WO/2011/012815A1
The present invention relates to the masking of the odour of organic sulphides and more particularly that of alkyl sulphides or of dialkyl sulphides, especially dimethyl sulphide, and also of oxides thereof, and especially of dimethyl su...  
WO/2011/012820A1
The invention relates to solvent compositions predominantly comprising at least one oxide of an organic sulfide, more particularly dimethyl sulfoxide, to which is added at least one odour-masking agent comprising at least one compound se...  
WO/2011/012247A1
Described are 2-(3-alkylthiobenzoyl)cyclohexanediones of the general formula (I) as herbicides. X, Y, R1 to R8 in this formula (I) stand for radicals such as hydrogen or organic radicals such as alkyl and alkoxy.  
WO/2011/008543A2
Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated...  
WO/2011/007146A1
Compounds of formula (I) are suitable for use as herbicides: wherein R is methyl, ethyl, vinyl, ethynyl or cyclopropyl, R1 is hydrogen, C1-C6alkyl, C1-C6haloalkyl, C3-C7cycloalkyl, C1-C6alkoxy, C1-C6haloalkoxy, vinyl, propenyl, ethynyl, ...  
WO/2011/005127A1
The present invention relates to a new stable crystalline polymorph of 2-(2-chloro-4-mesyl-benzoyl)-cyclohexane-1,3-dione and to a process for preparing the same. More particularly, it relates to compositions having said polymorph for co...  
WO/2010/107807A3
The present invention is directed to a compound of 2-N halo-4-methylsulfonyl-butyric acid, such as 2-N chloro-4-methylsulfonyl-butyric acid, or a pharmaceutically acceptable salt or solvate thereof. The present invention is also directed...  
WO/2010/148488A1
The present invention relates to compounds capable of inhibiting and/or decreasing the activity of one or more cathepsins, thereby treating and/or preventing various disease states associated with one or more cysteine proteases including...  
WO/2010/144959A1
The present invention relates to analogues of anti-fibrotic agents having the formula (I) with the substituents as described within the specification. The present invention also relates to methods for their preparation.  
WO/2010/147228A1
A pattern forming method, including: (i) forming a film from a chemical amplification resist composition; (ii) exposing the film, so as to form an exposed film; and (iii) developing the exposed film by using a developer containing an org...  
WO/2010/142650A1
The invention relates to compounds of formula (I) wherein A1, R1, R2, R3, R4 and R5 are defined in the description and in the claims, which are preferential inhibitors of the cysteine protease cathepsin, in particular of the cysteine pro...  
WO/2010/143578A1
Provided are a process for preparing alkyl sulfone compounds easily and safely in a high yield, and alkyl sulfone compounds. Specifically provided is a process for the preparation of alkyl sulfone compounds of general formula (2) which c...  
WO/2010/139090A1
N-Phenyl dichloroacetamide and their derivatives which belong to pharmaceutical chemistry and organic synthesis fields are provided. These compounds have the structures of general formula I, in which N-{3-chloro-4-[(trifluoromethyl)sulfo...  
WO/2010/137620A1
Disclosed is a phenoxyethylamine derivative having an excellent selective α1D adrenergic receptor antagonistic activity. Specifically disclosed is a compound represented by formula (I) [wherein each symbol is as defined in the descripti...  
WO/2010/103297A3
There is provided compounds of formula (I), wherein Y, ring A1 D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of dise...  
WO/2010/130124A1
A new preparation of aliphatic amines with sulphonyl group and their salts, using sulfonates with sulphonyl group as raw material and ammonia or amine as substituent reagent reacting with the raw material to obtain the product. A new kin...  
WO/2010/126349A1
The object of the present invention is to demonstrate that it is possible to prepare a soluble pharmaceutical form of N,N'-diaminodiphenyl sulphone that can be used to produce an optimum drug for use against cerebral infarction, epilepsy...  
WO/2010/123139A1
Disclosed is a long-chain fatty acid elongase (Elovl6) inhibitor, which is characterized by comprising at least one of a compound represented by formula (I), a pharmaceutically acceptable salt of the compound, and a solvate of the compou...  
WO/2010/123071A1
Disclosed is a dye composition which has high clarity and color developability, while exhibiting excellent fastnesses such as heat resistance, wet heat resistance and water resistance. Specifically disclosed are a triarylmethane compound...  
WO/2010/122968A1
Disclosed is a compound useful as an anti-obesity agent. Studies have been made on compounds which have a DGAT1 inhibitory activity and are therefore promising active ingredients for pharmaceutical compositions for treating obesity, type...  
WO/2010/115945A1
The present invention relates to a compound of the general formula (I) where: X = S, SO or SO2; and one of the radicals R1 and R2 is a hydrogen atom and the other is a radical: a C1 to C18 linear or branched alkyl, optionally substituted...  

Matches 401 - 450 out of 10,966