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Matches 1 - 50 out of 10,709

Document Document Title
WO/2018/184936A1
It is described an industrially viable and advantageous process for the preparation of (S)-beta-aminosulfone (1) starting from the corresponding racemic compound, said (S)-beta-aminosulfone being a useful intermediate for the preparation...  
WO/2018/184933A1
It is described an industrially viable and advantageous process for the preparation of racemic beta-aminosulfone (1), an useful intermediate for the preparation of N-(2-((1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)et hyl)-2,3-dih...  
WO/2018/178860A1
The present disclosure relates to a method for the synthesis of mesotrione. The method comprises reacting p-toluene sulfonyl chloride with alkali metal sulphite and alkali metal bicarbonate to obtain p-toluene alkali metal sulfinate. The...  
WO/2018/177865A1
The present invention relates to the use of compounds having an anti- heparanase activity of formu la [R - L1- Ar1- L - Ar]2- X, wherein X is selected from the group consisting of SO2, C1 -C4 a lkylene, linear or branched, and wherein Ζ...  
WO/2018/174253A1
[Problem] To provide a fluorescent probe with which it is possible to selectively detect GSTP1 activity. [Solution] A nitrobenzene derivative represented by general formula (1) [in the formula, the symbols are defined as in the specifica...  
WO/2018/172503A2
A liquid laundry detergent comprising the adduct of a) a vinyl sulfone monomer of formula (I) wherein R is an organic radical with up to 500 carbon atoms and R may comprise heteroatoms selected from O, N or S and b) a saccharide having a...  
WO/2018/165257A1
Disclosed are dendritic anionic lipids which are compounds of Formula (I) : wherein R and R1 are non-polar groups, L is a linking moiety, and Dm is a dendritic moiety of m generations, each as defined herein. These dendritic anionic lipi...  
WO/2018/157240A1
The disclosure relates to a compound of formula: (I) Several different uses of this compound are described for preparing different compounds. For example, this compound makes it possible to graft a fluorosulfonyl group on a molecule. A m...  
WO/2018/149991A1
The present invention relates to particular sulfonamide derivatives, the pharmaceutically acceptable addition salts thereof, the hydrates thereof and/or the solvates thereof, and also the use thereof as inverse agonists of retinoid-relat...  
WO/2018/145653A1
The present invention relates to the technical field of chemical medicine and relates to a compound represented by formula (I) or formula (II) and a preparation method therefor, the compound being a biaryl derivative and having retinoid-...  
WO/2018/144869A1
Disclosed herein, inter alia, are compositions and methods useful for inhibiting ubiquitin-like modifier activating enzyme 5.  
WO/2018/144870A1
Disclosed herein, inter alia, are compositions and methods useful for inhibiting reticulon 4(RTN4).  
WO/2018/143923A1
The present disclosure is drawn to an amine synergist including a tertiary benzylamine with a substituted benzene ring attached to a tertiary amine. The tertiary amine can be modified with multiple water soluble groups.  
WO/2018/139607A1
[Problem] To provide a complex which contains a tin ion (Sn2+) or a bismuth ion (Bi3+) with a high purity and is suitable for the production of a lead-free perovskite compound. [Solution] A complex which is represented by general formula...  
WO/2018/135373A1
The present invention addresses the problem of providing a novel alkoxymethyl-substituted bisphenol compound having exceptional storage stability and exceptional solvent solubility, heat resistance, and optical properties when used as a ...  
WO/2018/104288A1
The present application relates to compounds according to (Formula IA) or (Formula IB): (Formula IA) (Formula IB) or a pharmaceutically acceptable salt thereof. The compounds can be used as inhibitors of RORγ and are useful for the trea...  
WO/2018/096066A1
This invention is directed at a mechanochemical process using at least one solid catalytically active compound for simulating or capturing the transformation over time of a solid pharmaceutical composition in a shortened time span and th...  
WO/2018/091430A1
Compounds of the formula (I), wherein R1, R2, R3, R4 and R5 are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions,...  
WO/2018/089402A1
There are described RORγ Gamma modulators of the formula (I), (I) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutic...  
WO/2018/083110A1
The invention relates to novel compounds having fluoridated terminal groups, to the use thereof as surface-active substances, and to agents containing said compounds.  
WO/2018/083933A1
This secondary battery is provided with a positive electrode, a negative electrode and an electrolyte solution which contains at least one sulfonyl compound selected from among those represented by R1(-O-C(=O)-R2-S(=O)2-Rf1)n1 or the lik...  
WO/2018/071741A1
The invention provides sulfoxyalkyl organonitro and related compounds, compositions containing such compounds, and methods for using such compounds and compositions to treat medical disorders, such as a neurodegenerative disorder, autoim...  
WO/2018/070303A1
Provided is a resist underlayer film-forming composition which is capable of providing a resist underlayer film, said resist underlayer film exerting a sufficient anti-reflection function particularly in a KrF process, a high solvent res...  
WO/2018/061034A1
The present invention relates to a process for the preparation of 1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethanamine, an intermediate for the preparation of apremilast via a compound of Formula (V) wherein R is (C1-C4)alkyl, (C1-C...  
WO/2018/064559A1
The present invention is directed to tablets for oral administration to a subject, comprising a therapeutically effective amount of SYN120 or a pharmaceutically acceptable salt thereof, wherein the tablet is substantially free of lactose...  
WO/2018/054877A1
The invention relates to a method for producing bistolanes which are substituted in the 1,1 '-position with halogen and to products from said compounds. The C-C-triple bonds of the bistolanes are produced by elimination reactions.  
WO/2018/048856A1
A method of radiolabeling a biomolecule using a microfluidic device includes loading one or more droplets containing a 18F-labeled prosthetic group on or into the microfluidic device and evaporating the droplet(s) containing the 18F-labe...  
WO/2018/047888A1
The present invention provides a compound that has an exceptional TLR4 signal-inhibiting action and can be useful as a drug for the prevention or treatment of autoimmune diseases and/or inflammatory diseases or diseases such as chemother...  
WO/2018/016657A1
The invention provides a compound of ethyl 6- [ (2-chloro- 4-fluorophenyl)methanesulfonyl] -3-methylcyclohex-1-ene-1- carboxylate. The compound possesses an advantageous combination of TLR4 antagonist properties and brain permeability, a...  
WO/2018/012947A1
The present invention relates to a novel organic sulfur compound, a method for preparing the same, and a pharmaceutical composition for preventing or treating cancer or an inflammatory disease, containing the same as an active ingredient...  
WO/2018/007481A1
A process for preparing polyaryl ethers in which a polycondensation of the monomer building blocks is carried out using microwave irradiation leads to thermoplastic molding compositions having improved color properties.  
WO/2018/001353A1
Provided is a method for preparing apremilast of formula I. Method one: (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamin e N-acetyl-L-leucine salt of formula II is reacted with 3-acetylaminophthalic anhydride of formula III i...  
WO/2017/219935A1
The present invention discloses a biaryl urea RORγt inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an RORγt inhibiting activity, and a manufacturing method thereof, and a pharmaceutic...  
WO/2017/208501A1
Provided are: a surface-modified sodium hypochlorite pentahydrate crystal, an aqueous solution of which has a pH which can be significantly lowered safely and simply and at low cost without performing risky, high-cost pH adjustment that ...  
WO/2017/209762A1
Disclosed herein are electrolyte compositions comprising a fluorinated solvent, a fluorinated sulfone, at least one component selected from a borate salt, and/or an oxalate salt, and/or a fluorinated cyclic carbonate, and at least one el...  
WO/2017/199103A1
The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein ring A, R1, R2, R3, R4, R5, n and p are as defined herein, which are active as modulators of retinoid-related orphan re...  
WO/2017/177292A3
The present invention relates to a method for the selective control of populations of hematophagic arthropods, replacing or supplementing the use of pyrethroid insecticides by the use of tyrosine metabolism enzyme inhibitors, more specif...  
WO/2017/177307A1
Compounds having a structure of Formula I or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, and X, are as defined herein, are provided. Uses of such compounds for modulat...  
WO/2017/164813A1
D The present invention relates to ion pair catalysts (I) comprising the cationic bisguanidinium ligand (A) and diperoxomolybdate anion (B). The present invention also relates to ion pair catalysts (III) comprising the cationic bisguanid...  
WO/2017/162390A1
New benzenesulfonyl asymmetric ureas are herein disclosed, corresponding to the general formulas (I) –(IV) and pharmaceutically acceptable salts thereof, whose structure and substituents are detailed in the specification. Procedures fo...  
WO/2017/153235A1
The invention relates to novel substituted N-cyclo-3-aryl-1-naphthamide derivatives, to methods for producing same, to the use thereof, either alone or in combination, for the treatment and/or prevention of diseases, and to their use for...  
WO/2017/150478A1
[Problem] To provide an industrially preferred method for producing a sulfoxide derivative. [Solution] A method for producing a sulfoxide derivative represented by general formula (1), the method being characterized in that a sulfide der...  
WO/2017/137147A1
The present invention relates to novel crystalline modifications of N-(4,5- bismethanesulfonyl-2-methylbenzoyl)guanidine hydrochloride, novel N-(4,5- bismethanesulfonyl-2-methylbenzoyl)guanidine salts and their crystalline modifications ...  
WO/2017/135293A1
The purpose of the present invention is to provide a solar cell which exhibits excellent photoelectric conversion efficiency, and in which a decrease in photoelectric conversion efficiency caused by continuous exposure to light (photodeg...  
WO/2017/129818A1
The invention relates to a method for purifying peptides which are produced by solid phase peptide synthesis (SPPS) and corresponding linker molecules for use in said method.  
WO/2017/131221A1
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4a and R4b are as defined in the specification, processes for their preparation, pharmaceutical compositions cont...  
WO/2017/130798A1
Disclosed is a polyarylene sulfide resin having a main chain including a structural unit represented by general formula (1.1). No absorption peak derived from the S=O stretching vibration of a sulfonyl group is observed in the infrared a...  
WO/2017/109178A1
A subject of the present invention is the use of a compound having the general formula (I): (I) wherein V, W, X4, X5, X6, X7, X'4, X'5, X'6, X'7, Y, Y', R3, R'3, R4 and R'4 are as defined in any one of claims 1 to 11, for the detection, ...  
WO/2017/102706A1
Processes for reducing the amount of a gaseous iodide-containing impurity present in a recycle gas stream used in the production of ethylene oxide, in particular alkyl iodide and vinyl iodide impurities, are provided. Processes for produ...  
WO/2017/098900A1
The present invention is a method for purifying dimethyl sulfoxide, comprising distilling a dimethyl sulfoxide-containing liquid in an inert gas atmosphere in the presence of sodium carbonate to distil out dimethyl sulfoxide, wherein the...  

Matches 1 - 50 out of 10,709