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WO/2009/156090A2 |
The present invention relates to sulfur-derivatized 1-azinylpyrazoles, the use thereof as insecticides and / or parasiticides and processes for the preparation thereof. Further objects of the present invention are various intermediates ...
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WO/2009/149192A1 |
Small molecule inhibitors of Stat3 and their derivatives are disclosed. Also described are methods to inhibit cell growth by use of Stat3 inhibitors, and the use of Stat3 inhibitors for the prevention and/or treatment of cancer. Further,...
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WO/2009/143309A2 |
The present invention provides methods for boosting mucosal immunity in the female reproductive tract of pre- and post -menopausal women using a TGF-beta inhibitor, a Selective Estrogen Receptor Modulator, and/or a recombinant commensal ...
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WO/2009/131796A1 |
Disclosed are thioethers, methods for preparing such thioethers, and curable compositions, such as coating and sealant compositions, that include such thioethers. The thioethers can be the reaction product of (a) an alpha, omega dihalo o...
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WO/2009/132010A1 |
The application discloses thiol ester molecules and α-hydroxy thiol ester molecules having a thiol group located on one of the final two carbon atoms in a carbon chain or a terminal or α- hydroxyl groups, respectively. The disclosed th...
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WO/2009/125191A1 |
Compounds with the general formula (I): are described wherein R1, R2, R3, R4, R5, Q, T, X, Y and Z are as defined. Compounds according to the invention can display potent inhibition against Hepatitis C Virus (HCV) helicase and potent ant...
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WO/2009/106713A2 |
The subject of the present invention is the development of a new family of cationic lipids and the use thereof as vectors for in vitro, ex vivo and in vivo delivery of biologically active agents.
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WO/2009/102808A2 |
Methods are provided for using doxorubicin active agents in which reduced host toxicity is observed. Aspects of the methods including administering to a subject an effective amount of a doxorubicin active agent in conjunction with a doxo...
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WO/2009/100431A1 |
The present invention provides cysteine and cystine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing prodrugs and methods of using the prodrugs and c...
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WO/2009/088102A2 |
Provided is a process for producing an amide (A) : by hydrating a nitrile (B) at high conversion in relatively short period of time even without use of high-capacity cooling apparatuses (25, 35) and a large amount of inorganic acid (D). ...
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WO/2009/076345A1 |
New methods for producing difluoromethylene-containing compounds with phenylsulfur trifluoride or a primary alkyl-substituted phenylsulfur trifluoride are disclosed. Also, new methods for producing trifluoromethyl-containing compounds wi...
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WO/2009/069888A2 |
The present invention relates to a novel synthesis method for the formation of carbon- sulfur bonds by the reaction of an organic sulfur-indium complex with nucleophile in the presence of a palladium catalyst. The present invention provi...
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WO/2009/060445A1 |
Therapeutic compounds based on synthetic sphingolipid analogs are provided, particularly alkylthiophenyl substituted ceramide analogs, suitable for treating degenerative, infectious, and other diseases.
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WO/2009/061208A1 |
The present invention relates to lipid compounds of the general formula (I): wherein • R1 is selected from a C10-C21 alkyl, a C10-C21 alkenyl having 1-6 double bonds, and a C10-C21 alkynyl having 1-6 triple bonds; • R2 and R3 are the...
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WO/2009/056069A1 |
A successive preparation method of the 3-isothiazolone derivates and their intermediates. This method includes four successive steps, that is sulfuration, purification, amination and chlorination. Comparing with the intermission method d...
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WO/2009/051025A1 |
This invention provides a process for producing an alkenylphosphorus compound using a hydrogenated phosphonic acid ester, a hydrogenated phosphinic acid ester, or a disubstituted phosphine oxide as a starting compound in the presence of ...
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WO/2009/018726A1 |
Antrodia camphoratacyclohexenone compounds which is effective in inhibiting hepatitis B virus, in particular 4-hydroxy-2,3-dimethoxy-6-methy-5 [3,7,11-trimethy-dodeca-2,6,10-trienyl]-cyclohex-2-enone isolated from an extract of Antrodia ...
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WO/2009/008905A1 |
Compounds having the formula : (I) wherein the symbols have the meaning described in the specification are hydroxamic acid derivatives of phenoxy-acetic acids and analogs capable of inhibiting the lethal effects of infection by anthrax b...
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WO/2009/000168A1 |
Antrodia camphorata cyclohexenone compounds used for decreasing physiological fatigue, in particular 4-hydroxy-2,3-dimethoxy-6-methy-5[3,7,11-trimethy- dodeca-2,6,10-trienyl]-cyclohex-2-enone isolated from extract of Antrodia camphorata,...
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WO/2008/148468A1 |
The present invention relates to di(hetero)arylcyclohexane derivatives of the formula (I), in which Ar1, Ar2, R1 and R2 have the meanings indicated in the claims. The compounds of the formula (I) are valuable pharmaceutical active compou...
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WO/2008/145488A1 |
The invention relates to a process for continuously preparing methyl mercaptan by reacting a reactant mixture which comprises solid, liquid or gaseous carbon- and hydrogen-containing compounds, air, water and sulfur.
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WO/2008/142037A2 |
The invention relates to a novel mixture which contains 2,2,4,6,6-pentamethylheptanthiol-4, 2,4,4,6,6-pentamethylheptanthiol-2, 2,3,4,6,6-pentamethylheptanthiol-2 and 2,3,4,6,6-pentamethylheptanthiol-3, to a method for producing said mix...
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WO/2008/116321A1 |
This invention relates to compositions of one or more compounds that incorporate one or more allyl sulfide, allyl disulfide or allyl polysulfide moieties, or one or more allyl sulfide, allyl disulfide or allyl polysulfide moieties and on...
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WO/2008/118925A2 |
A process and graded catalyst bed for selectively producing methyl mercaptan from methanol. The methanol is reacted with hydrogen sulfide, in the presence of a graded catalyst bed containing at least three types of nickel or cobalt molyb...
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WO/2008/111414A1 |
Disclosed is a catalyst composition comprising a fluoride of iron or cobalt and a nitrogenated heterocyclic compound represented by the general formula (1A) or (1B). (1A) or (1B) wherein R1 and R2 independently represent a substituted or...
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WO/2008/110698A2 |
The invention relates to a method for preparing polyfluorinated sulphanylamides of formula (I) and polyfluorinated sulphinamidines of formula (II), wherein R1-R4 are defined as in the claims, and for preparing the precursors of same.
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WO/2008/108735A1 |
The present invention relates to 2-(substituted sulphur, sulphone or sulphoxide)-3-(substituted phenyl) propionic acid derivatives, 2-(substituted oxygen)-3-(substituted phenyl) propionic acid derivatives, benzoic acid derivatives, and d...
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WO/2008/107622A1 |
The present invention concerns an additive for reducing the formation of coke and/or carbon monoxide in thermal hydrocarbon cracking units and/or of other organic compounds in heat exchangers. The additive according to the invention is e...
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WO/2008/109840A1 |
This invention is directed to, for example, compounds of formula (I): wherein n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically accep...
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WO/2008/101806A2 |
The invention relates to novel sulfur-containing (meth)acrylic monomers and compositions thereof characterized by a high refractive index, for optical and industrial applications. The invention also relates to a method for preparing high...
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WO/2008/098810A2 |
The invention relates to a method for the continuous production of alkyl mercaptan by reacting an educt mixture containing dialkyl sulfides and dialkyl polysulfides, with at least one molar excess of hydrogen sulfide at a higher temperat...
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WO/2008/091818A1 |
Disclosed herein is a compound of the formula (I). Therapeutic methods, compositions, and medicaments, related thereto are also disclosed.
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WO/2008/087330A2 |
The present invention relates to a sulphidation agent for a hydroprocessing catalyst that provides a faster sulphidation of the catalyst and also significantly reduces solid deposits, essentially sulphur. The sulphidation agent of the pr...
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WO/2008/074677A1 |
The present invention relates to a process for the preparation of 1 -(2-cthyl-butyl)-cyclohexanecarboxylic acid which is useful as an intermediate in the preparation of, pharmaceutical active compounds, comprising reacting cyclohexanecar...
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WO/2008/059217A1 |
Diallylic polysulfides (polysulfanes) are provided with sulfur chain lengths of 9 to 22. Also provided are bis(2-methyl-2-propenyl) polysulfides with sulfur chain lengths of 3 to 22. Also provided are 2-substituted bis(2-propenyl) polysu...
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WO/2008/059213A1 |
A method of producing polysulfides comprising the step of adding elemental sulphur to an allicin-containing plant extract. In preferred embodiments, the plant extract is mechanically treated members of the genus Allium, especially garlic...
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WO/2008/046801A2 |
The invention relates to a method for producing thiols by adding hydrogen sulphide to at least one unsaturated terpene, the reaction being carried out in the presence of at least one organic ion exchanger. The invention also relates to t...
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WO/2008/015139A2 |
There are described compounds having the general formula (I) below and their pharmaceutically acceptable salts thereof, wherein E, X, m, q, R1, R2, n and ZBG have the meanings reported in the description useful, in therapy, as inhibitors...
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WO/2008/006657A1 |
The invention relates to a method for producing alkylmercaptans by the catalytic gas-phase conversion of alkanols and hydrogen sulfide on alkali tungstates, wherein the conversion is carried out in at least two successive reaction zones ...
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WO/2008/003447A2 |
The invention relates to the use of Y terminal groups, wherein Y represents CF3(CH2)aS- or CF3CF2S- or [CF3- (CH2)a]2N-, a represents a whole number selected from the range of 0 to 5, as terminal groups in surface-active compounds. The i...
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WO/2008/002817A1 |
Certain substituted butyl and butynyl benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
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WO/2007/134537A1 |
Organic compounds containing heteroatoms and their use in preparing Ziegler-Natta (Z-N) catalyst with single activation center. The Z-N olefin polymerization catalyst is prepared by adding organic or inorganic solid carrier or compound o...
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WO/2007/129450A1 |
Disclosed is a process for production of a (poly)thiol compound for use as an optical material. The process comprises reacting an organic (poly)halogen compound or a (poly)alcohol compound with thiourea to produce an isothiuronium salt a...
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WO/2007/128137A1 |
A monomer of formula (I) may be used to prepare a poly(arylene ether) of formula (II) wherein k is 1 or 2, n is a non-zero number from 0 to 1, j is 0, 1 or 2, Q is O or S, L is a leaving group, Z is F or CI, Z' is F, CI or an organic gro...
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WO/2007/129449A1 |
Disclosed is a method for producing a polythiol compound for optical materials, wherein a 2-mercaptoethanol having a bis(2-hydroxyethyl)disulfide content of not more than 0.5% by weight is reacted with an epihalohydrin compound, thereby ...
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WO/2007/120083A1 |
The use of a compound of formula (I) wherein: X is (CH2)m, O, O(CH2)m or (CH2)mO; Y is (CH2)n, CHR5(CH2)n or (CH2)nCHR5; R1 and R4 are, independently, aryl or heteroaryl; each independently optionally substituted by halo, C1-6 alkyl, C1-...
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WO/2007/103221A2 |
The invention encompasses processes for preparing intermediates, such as (R)-modafinic acid and its C1-2 alkyl ester, and the conversion of the intermediates into armodafinil. In particular, the invention concerns: (i) a process for the ...
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WO/2007/103719A2 |
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with express...
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WO2007010387B1 |
Methods and materials for preparing optically active 3,4-disubstituted cyclopentanones are disclosed. The method includes hydrolyzing one or more compounds represented by Formula (13), or removing an ester moiety from a compound represen...
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WO/2007/071609A1 |
Compounds of formula I wherein X is O or S(=O)n; n is 0,1 or 2; R1 is optionally substituted alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, cycloalkenyl, halocycloalkenyl, phenyl, hetaryl, pheny...
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