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WO/2021/043188A1 |
Provided in the present disclosure is a mixture, comprising: 86-89 wt% of a methionine hydroxy analog and an oligomer thereof, more than 99.95 wt% being a monomer, dimer and trimer, and the ratio of monomer:dimer:trimer by weight being 7...
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WO/2021/027933A1 |
The embodiment of the present invention relates to the field of the synthesis of mercapto compounds, in particular to a method for preparing 3-mercaptopropionic acid. The preparation method provided in the present invention comprises: mi...
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WO/2021/030703A1 |
Disclosed herein, inter alia, are depalmitoylating compounds, compositions, and methods of use thereof.
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WO/2021/016535A1 |
A novel Low Free 2-MercaptoEthanol Ester has been used to prepare Alkyl Tin Reverse Ester Stabilizers as well as used to enhance the thermal performance of those Alkyl Tin Reverse Ester Stabilizers or Alkyl Tin Thioglycolate Stabilizers ...
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WO/2021/011334A1 |
The invention provides new deuterated derivatives of 6,8-bis(benzylsulfanyl)octanoic acid, pharmaceutical compositions thereof, and methods for treating cancer with the new compositions.
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WO/2020/258660A1 |
The present application relates to a crystal form of a valnemulin hydrochloride hydrate, a preparation method therefor, and a pharmaceutical composition containing the crystal form. Specifically, the present application relates to a crys...
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WO/2020/262455A1 |
The present invention provides a means for increasing the solubility of even a poorly soluble amino acid without changing to an expensive peptide and also without changing the pH, and is characterized in that at least two kinds of amino ...
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WO/2020/262451A1 |
The invention addresses the problem that metal-organic frameworks have conventionally only been produced with terephthalic acids having a limited range of substituents even though the amount and type of gas stored thereby can vary depend...
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WO/2020/255425A1 |
This anti-HBV agent contains a compound represented by general formula (I) or a compound represented by general formula (II), or a salt thereof.
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WO/2020/254403A1 |
The invention relates to a single cycle process for preparing D,L-methionine from an alkali methioninate solution obtained by alkaline hydrolysis of 5-(2-methylmercaptoethyl)hydantoin, in which the D,L-methionine is obtained by neutraliz...
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WO/2020/251368A1 |
The present invention describes liposome formulations comprising a phospholipid, cholesterol and a fatty acid compound or fatty acid containing compound. Also, various medical uses of the liposome formulation are described.
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WO/2020/249495A1 |
The present invention relates to a process for the preparation of methionine comprising the step of contacting a solution or suspension comprising 2-amino-4-(methylthio)butanenitrile and/or 2-amino- 4-(methylthio)butaneamide with water i...
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WO/2020/244323A1 |
Disclosed are a preparation method for a cis-p-mentha-1,8-secondary amine compound and a herbicidal application thereof. The method comprises: using a cis-p-mentha-1,8-di-schiff base compound as a raw material, putting reducing agents in...
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WO/2020/243986A1 |
The present invention relates to a fluorine-containing alternating copolymer macromonomer and a synthesis method therefor. The method comprises the following steps: carrying out a reduction reaction on a fluorine-containing alternating c...
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WO/2020/229393A1 |
A process for the synthesis of compounds comprising at least one non-cyclic carbonate group is provided, wherein a compound A) comprising at least one five-membered cyclic monothiocarbonate group is reacted with at least one hydroxy grou...
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WO/2020/227079A1 |
This disclosure is directed to the use of a portable Surface Enhance Raman Spectroscopy method to detect, quantify, and/or monitor corrosion inhibitors that are present in fluids in a wide range of concentrations in order to manage corro...
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WO/2020/224767A1 |
The present invention relates to compounds of formula (I) as herein defined, capable of releasing fragrant compounds in a controlled manner into the surroundings. The present invention is also concerned with a process for their productio...
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WO/2020/221607A1 |
A process to produce a mono vinyl thioether by reacting acetylene with a compound comprising one thiol group and one hydroxy group, hereinafter referred to as thiol-hydroxy compound, wherein the reaction is performed at a pressure below ...
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WO/2020/218508A1 |
The thiol-containing composition for an optical material of the present invention includes a compound (A) represented by general formula (a) and a compound (B) comprising at least one selected from compounds (b2-1) represented by general...
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WO/2020/218527A1 |
An ionic solid having void spaces in which a substance is to be incorporated.
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WO/2020/212543A1 |
The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive unit, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalm...
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WO/2020/214946A1 |
The present invention provides, in part cystine cationic lipid compounds of formula A, and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mR...
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WO/2020/208594A1 |
The present invention provides various solid state forms of elafibranor. In an aspect of present invention provides a stable amorphous form of elafibranor and its processes. The present invention also provides a stable admixture form of ...
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WO/2020/201412A1 |
The invention relates to a method for preparing a compound of formula (I) [Chem I], in which X is chosen among S, Se; R1 is chosen from among the alkyl, aryl, alkylaryl and heteroaryl groups, optionally carriers of one or more function, ...
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WO/2020/198573A1 |
The present disclosure relates to compounds of Formula (I) or (II): (Formulae (I), (II)), and pharmaceutically acceptable salts or solvates thereof. The present disclosure also relates to pharmaceutical compositions comprising the compou...
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WO/2020/175838A1 |
Disclosed is a novel diamine compound comprising a structure in which diphenyl sulfide in a molecule is bonded through an amide bond to a phenyl ring substituted with an amine group. A polyimide film prepared by polymerizing the novel di...
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WO/2020/168385A1 |
The present invention relates to a method of preparing N-acyl amino acids selected from N-acyl cysteine compounds, N-acyl serine compounds, N-acyl aspartic acid compounds and N-acyl glutamic acid compounds. The present invention also rel...
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WO/2020/161074A1 |
The invention refers to the use of a particulate catalyst containing 60.0 to 99.5 wt.% ZrO2 stabilised with an oxide of the element Hf and at least one oxide of the element M, wherein M = Ce, Si, Ti, or Y, for the hydrolysis reaction of ...
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WO/2020/161067A1 |
The present invention relates to a process for the preparation of methionine comprising the step of contacting a solution or suspension comprising 2-amino-4-(methylthio)butanenitrile and/or 2-amino-4-(methylthio)butaneamide with water in...
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WO/2020/157463A1 |
Disulphide compounds of Formula (I) where Y is sulphuryl or sulphinyl Z is phenyl or substituted phenyl and the other variables are as defined in the claims; pharmaceutical compositions comprising these compounds and methods for making t...
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WO/2020/154160A1 |
A composition comprising a compound having the general formula (I): F – [CF2]n – (O[CF2]n)m –( L )p – SH (Formula (I)) Each n is independently from 2 to 4, m is from 3 to 30, p is 0 or 1 and L represents a linker having the formu...
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WO/2020/148617A1 |
The present invention disclosed 3-substituted phenylamidine compounds of general formula (I), wherein R1, R2, R3, R4, R4a, R4b, A and E have the same meanings as defined in description. The present invention further discloses methods for...
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WO/2020/148509A1 |
The invention relates to an agent for initiating a radical addition reaction, comprising or consisting of a persulfate and one or more transition metals, in elemental form or in an oxidized form, and to a process for preparing a compound...
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WO/2020/145111A1 |
An objective of the present invention is to provide: a novel thiol compound; a method for synthesizing said thiol compound; a curing agent containing said thiol compound; a resin composition containing said thiol compound and an epoxy co...
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WO/2020/120720A1 |
The present invention pertains to a method for producing methionine or salts or derivatives thereof from hydrogen cyanide (HCN), the method comprising a step of producing 2-hydroxy-4-(methylthio)butyronitrile (MMP-CN), or a crude product...
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WO/2020/114376A1 |
The present invention provides a preparation method for a chemical intermediate 2,2'-dithiocarbamides compound. A 2-position substituted benzamides compound is reacted with a sulfur reagent in an aprotic solvent of a high boiling point u...
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WO/2020/115037A1 |
The present invention relates to a sulphur-containing polyester obtainable by a process comprising esterification reactions between a polyol and a carboxylic acid and a thiolactic acid, or by a process comprising an esterification reacti...
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WO/2020/115628A1 |
The present invention relates to solid forms of elafibranor of Formula I, and process of preparation thereof, wherein said solid forms includes amorphous, crystalline, solid dispersion and premix with pharmaceutically acceptable polymer ...
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WO/2020/113209A1 |
The present disclosure relates to compounds of Formula (I), (II), or (II'): (I), (II), (II'), and pharmaceutically acceptable salts or solvates thereof. The present disclosure also relates to pharmaceutical compositions comprising the co...
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WO/2020/104589A1 |
The invention relates to the use of a chemical compound of formula (I), certain compositions containing 3-methylthiopropionaldehyde, 3-methylthio-1,1-propanediol, a compound according to formula I and water, also: methods for the product...
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WO/2020/102529A1 |
A method comprising co-administering to a subject having cancer, suspected of having cancer, or at risk of developing cancer: a therapeutically effective amount of at least one compound (a) selected from (a)(i) a nitroalkene fatty acid, ...
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WO/2020/095031A1 |
Organosulfur compounds of formula (I), where R1 and R2 are as defined herein, and pharmaceutical compositions comprising these organosulfur compounds. Uses of the organosulfur compounds and the pharmaceutical compositions for treating in...
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WO/2020/083018A1 |
A method for preparing a sulfur-containing biphenyl compound as shown in the general formula (I), the reaction formula aa being as shown in the specification. The method for coupling reaction under the combined action of metal and zinc u...
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WO/2020/079541A1 |
The present invention provides a process for elafibranor, the process comprising reacting compound of formula II or the compound of formula III with a compound of formula IV. The present invention also involve purification of elafibranor...
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WO/2020/074964A1 |
The present disclosure relates to compounds of the general formula (I): wherein R1, R2, R3, R4, R5, R6, and R7 may be chosen from different substituents; n is 0, 1, or 2; and X is a hydroxymethyl or a carboxylic acid or a derivative ther...
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WO/2020/069860A1 |
The invention relates to a process for preparing methionine amide by hydrolyzing methionine nitrile in the presence of 0.5 to 1.5 molecular equivalents of a ketone as a carbonyl-containing catalyst and of 0.03 to 0.10 molecular equivalen...
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WO/2020/069862A1 |
The invention relates to a process for preparing α-amino acid amide, especially methionine amide, by hydrolyzing the corresponding α-amino acid nitrile, especially methionine nitrile, in the presence of a ketone and guanidine as a cata...
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WO/2020/069859A1 |
The invention relates to a process for preparing α-amino acid amide, especially methionine amide, by hydrolyzing the corresponding α-amino acid nitrile, especially methionine nitrile, in the presence of a ketone and a secondary amine a...
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WO/2020/061367A1 |
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions fu...
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WO/2020/047985A1 |
The present invention belongs to the technical field of chemical preparation, and particularly relates to a difluoromethylation agent, preparation therefor and use thereof. Aiming at the key problem of poor stability of current electroph...
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