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Matches 1 - 50 out of 19,545

Document Document Title
WO/2018/188763A1
The present invention concerns a process for the preparation of firocoxib, i.e. 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylpheny l)-furan-2-one, comprising steps (a)-(g), wherein the process provides for step (d) of the react...  
WO/2018/183538A1
Disclosed herein, inter alia, are nucleotide analogues, and methods of use thereof, having cleavable orthogonal linkers.  
WO/2018/181986A1
The present invention provides a pharmaceutical composition for treating or preventing cognitive function disease or disorder, the composition comprising a compound represented by formula (I), an enantiomer thereof, a diastereomer thereo...  
WO/2018/177588A1
The invention relates to novel ester compounds based on bi-, tri- or higher functional carboxylic acids of general formula (I) and to a method for the production thereof and the use thereof in lubricants.  
WO/2018/167405A1
The invention concerns a method for manufacturing 2-hydroxy-4-(methylthio)butyric acid (HMTBA) from 2-hydroxy-4-(methylthio)butyronitrile (HMTBN), comprising the following steps: hydrolysing the HMTBN to HMTBA in the presence of a minera...  
WO/2018/162364A1
The present invention refers to a process for a catalytic aryl transfer to rearrange the backbone of aromatic C-X bonds.  
WO/2018/159650A1
The purpose of the present invention is to provide a compound which has a guanidine skeleton and inhibits the protease activity of MALT1 to exhibit a therapeutic effect or prophylactic effect on autoimmune diseases such as psoriasis. The...  
WO/2018/157232A1
Compositions comprising modulators of N-terminus activation of the androgen receptor, such as EPI-002 and EPI-506, and a second therapeutic agent are provided. Use of such compositions for treatment of various indications, including pros...  
WO/2018/151501A1
The present invention relates to a novel polyol or polythiol having three or more functional groups, a preparation method therefor, and an optical body manufactured therefrom. Especially, the present invention relates to a poly(thio)uret...  
WO/2018/148254A1
Provided herein are cysteamine or a pharmaceutically acceptable salt thereof and methods of using such for treating asthma (e.g. , moderate to severe persistent asthma) or reducing the risk of asthma occurrence.  
WO/2018/144717A1
The present invention is directed to novel pleuroniutilin antibiotic compounds, intermediates which are useful for making these novel amibioiic compounds aad related methods and pharmaceutical compositions for treating pathogens, especia...  
WO/2018/137874A1
The present invention relates to a multi-step process for the production of dihydrolipoic acid, which can particularly be carried out as a one-pot reaction and without isolation of intermediates.  
WO/2018/139186A1
Provided is a curable composition which has excellent storage stability and suppresses the generation of residue in unexposed portions, and from which a cured film having an excellent pattern shape can be obtained. Also provided are: a c...  
WO/2018/133705A1
The present invention relates to crystal forms of GFT-505 and a preparation method and use thereof. The provided crystal forms of GFT-505, CS1, CS2, CS5, and CS6, have high purities, good stabilities, low hygroscopicities, good solubilit...  
WO/2018/129609A1
Compounds of formula (II) are useful in modulating voltage-gated sodium channel activity. Their preparation and use for reducing the severity of convulsant activity in a subject, for example in the treatment of epilepsy, is presented.  
WO/2018/122511A1
The invention relates to the field of organic polysulphides, more particularly to a method for synthetising functionalised organic polysulphides of formula (I): R2-X-(NR1R7)C*H-(CH2)n-Sa-(CH2)n-C*H(NR1R7)-X-R2, in which the various subst...  
WO/2018/124803A1
The present application relates to a method for preparing L-methionine crystals with improved bulk density. As the L-methionine crystals prepared according to the method for preparing L-methionine crystals of the present application may ...  
WO/2018/114640A1
The present invention relates to a method for preparing methionine or methionine salts. In particular, the invention describes the step of preparing 2-hydroxy-4-(methylthio)butyronitrile (MMP-CN) from 3-methylthiopropanal (MMP) and hydro...  
WO/2018/110406A1
[Problem] To provide a luminescent nanocrystal composite which is orderly dispersed in a polymer matrix easily and exhibits excellent dispersibility in a crosslinkable polymer matrix having a mesogen structure. [Solution] The present inv...  
WO/2018/101057A1
Provided are a compound useful as a mold release agent, a mold release agent containing same, a curable composition, and a nanoimprint lithography resin material. Specifically, the present invention provides: a calixarene compound with a...  
WO/2018/099203A1
The present invention describes a crystalline form of oxamyl of formula (I), a crystal preparation process, the analyses of the crystal through various analytical methods and using the crystalline form to prepare a stable agrochemical fo...  
WO/2018/100008A1
The present invention relates to a process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol comprising the following steps: a) the reaction of a solution of amifostine with a strong acid, to obtain a solution of 2-...  
WO/2018/094960A1
The present invention relates to a cinnamic acid benzoyl methyl ester compound of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13 and R14 are as defined in the description. The present invention also relates t...  
WO/2018/091430A1
Compounds of the formula (I), wherein R1, R2, R3, R4 and R5 are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions,...  
WO/2018/073157A1
The invention relates to a method for producing 3-alkylsulfanyl-2-chloro-N-(1-alkyl-1H-tetrazol-5-yl)-4-trif luoromethyl-benzamides of formula (I). In said formula, the substituents R1 and R2 represent residues such as alkyl and substitu...  
WO/2018/070543A1
The purpose of the present invention is to provide a method for producing a phosphoramidite suitable for nucleic acid production (synthesis) with high efficiency and high purity. A phosphoramidite which allows for efficient nucleic acid ...  
WO/2018/066646A1
The present invention addresses the problem of finding a novel medicine which has an excellent tryptophanase inhibitory effect, suppresses indoxyl sulfate production in blood to thereby prevent deterioration of renal function, and thus c...  
WO/2018/058534A1
The present invention relates to the field of medicinal chemistry. Disclosed are a pleuromutilin derivative having a 2-amino phenyl mercaptan side chain, a preparation method therefor, and uses thereof. The compound has the structures re...  
WO/2018/060076A1
The present invention relates to novel triazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmf...  
WO/2018/060373A1
The present invention relates to drugs derived from elafibranor. It relates more specifically to a composition comprising at least one active ingredient, characterised in that at least one active ingredient comprises an elafibranor metfo...  
WO/2018/060354A1
The present invention relates to compounds of formula (I) and to pharmaceutical compositions containing them, wherein meanings of the substituents are indicated in the description. Such compounds for use in the treatment of cancer and ot...  
WO/2018/056237A1
Provided are a new dielectric material and an electrostrictive material. The dielectric material or electrostrictive material comprises a charge separated-type non-coulombic ionic solid in which complex cations comprising metal elements ...  
WO/2018/033493A1
The present invention relates to liquid aromatic thioethers, a process for the preparation of the liquid aromatic thioethers, an article comprising the liquid aromatic thioethers as well as the use of the liquid aromatic thioethers as a ...  
WO/2018/028050A1
Disclosed is an asymmetric aryl-alkyl persulfate compound as represented by formula (3) and a synthesis method therefor, in which an arylboronic acid of formula (1) and R2SSCOR3 of formula (2) serve as reaction raw materials and, under t...  
WO/2018/030816A1
The present invention relates to a novel compound exhibiting anti-oxidative or anti-inflammatory activity and a preparing method therefor, a pharmaceutical composition comprising the compound or a salt thereof as an active ingredient for...  
WO/2018/022871A1
Embodiments are directed to terphenyl ligands and metal complex formed therefrom, wherein the metal complexes are used as procatalyst in polyolefin polymerization and comprise the following structure:  
WO/2018/021338A1
The present invention is a method for producing a specific α-amino acid in which a specific α-amino acid amide and water are reacted with each other in the presence of a zirconium compound, wherein the zirconium compound contains zirco...  
WO/2018/015797A1
An object of the present invention is to provide a benzylamide compound or a salt thereof that controls a mite. The present invention provides a benzylamide compound represented by Formula (1): or a salt thereof, wherein R1 represents C1...  
WO/2018/015852A1
An object of the present invention is to provide a benzylamide compound or a salt thereof that controls a mite. The present invention provides a benzylamide compound represented by Formula (1): or a salt thereof, wherein R1 represents C1...  
WO/2018/003059A1
Provided is a method for preparing a polythiol compound, the method comprising: step 1 for reacting 2-mercaptoethanol, which has a water content of 3000 ppm or less on a mass basis, with epihalohydrin to obtain a halide represented by fo...  
WO/2017/221620A1
Provided are: a curable composition which has excellent light exposure sensitivity and enables the achievement of a cured film that exhibits excellent adhesion to a supporting body; a cured film; a color filter; a light-blocking film; a ...  
WO/2017/206703A1
A methionine new crystal form I, the crystal form II having diffraction peaks at 21.751±0.2°, 22.168±0.2°, 21.186±0.2°, 25.426±0.2°, 18.395±0.2°, and 32.879±0.2° at the diffraction angle 2θ. The methionine crystal form I of ...  
WO/2017/206704A1
A methionine new crystal form II, the crystal form II having diffraction peaks at 22.304±0.2°, 33.757±0.2°, 45.674±0.2°, 28.104±0.2°, 18.615±0.2°, and 42.739±0.2° at the diffraction angle 2θ. The methionine crystal form II o...  
WO/2017/206801A1
Disclosed are a class of diarylsulfide derivatives, a preparation method therefor, and the use thereof as a serotonin transporter-targeted imaging agent, belonging to the field of radiopharmaceutical chemistry. The diarylsulfide derivati...  
WO/2017/202266A1
The present invention relates to a 2-amino-3-substituted mercaptopropionate derivative, a preparation method therefor and a use thereof. The 2-amino-3-substituted mercaptopropionate derivative according to the present invention has a str...  
WO/2017/195149A1
Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.  
WO/2017/191196A1
There is provided a method of producing a method of producing methionine, the method comprising - contacting vinylglycine or derivatives thereof with at least one free radical methyl mercaptanin a reaction medium.  
WO/2017/191195A1
There is provided a method of producing at least one unsaturated amino acid from at least one amino acid comprising at least two carbonyl groups, the method comprising (a) contacting a recombinant microbial cell with a medium comprising ...  
WO/2017/188297A1
Provided is a resist composition that improves acid generation efficiency and is used to produce a photoresist having high sensitivity, high resolution, and high LWR properties. The present invention relates to a compound represented by ...  
WO/2017/187859A1
The present invention is a compound represented by formula (1), a liquid crystal composition containing the compound, and a liquid crystal display element including the composition. In the formula: R is a C1-15 alkyl or the like; ring A1...  

Matches 1 - 50 out of 19,545