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Matches 1 - 50 out of 19,879

Document Document Title
WO/2020/102529A1
A method comprising co-administering to a subject having cancer, suspected of having cancer, or at risk of developing cancer: a therapeutically effective amount of at least one compound (a) selected from (a)(i) a nitroalkene fatty acid, ...  
WO/2020/095031A1
Organosulfur compounds of formula (I), where R1 and R2 are as defined herein, and pharmaceutical compositions comprising these organosulfur compounds. Uses of the organosulfur compounds and the pharmaceutical compositions for treating in...  
WO/2020/083018A1
A method for preparing a sulfur-containing biphenyl compound as shown in the general formula (I), the reaction formula aa being as shown in the specification. The method for coupling reaction under the combined action of metal and zinc u...  
WO/2020/079541A1
The present invention provides a process for elafibranor, the process comprising reacting compound of formula II or the compound of formula III with a compound of formula IV. The present invention also involve purification of elafibranor...  
WO/2020/074964A1
The present disclosure relates to compounds of the general formula (I): wherein R1, R2, R3, R4, R5, R6, and R7 may be chosen from different substituents; n is 0, 1, or 2; and X is a hydroxymethyl or a carboxylic acid or a derivative ther...  
WO/2020/069860A1
The invention relates to a process for preparing methionine amide by hydrolyzing methionine nitrile in the presence of 0.5 to 1.5 molecular equivalents of a ketone as a carbonyl-containing catalyst and of 0.03 to 0.10 molecular equivalen...  
WO/2020/069862A1
The invention relates to a process for preparing α-amino acid amide, especially methionine amide, by hydrolyzing the corresponding α-amino acid nitrile, especially methionine nitrile, in the presence of a ketone and guanidine as a cata...  
WO/2020/069859A1
The invention relates to a process for preparing α-amino acid amide, especially methionine amide, by hydrolyzing the corresponding α-amino acid nitrile, especially methionine nitrile, in the presence of a ketone and a secondary amine a...  
WO/2020/061367A1
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions fu...  
WO/2020/047985A1
The present invention belongs to the technical field of chemical preparation, and particularly relates to a difluoromethylation agent, preparation therefor and use thereof. Aiming at the key problem of poor stability of current electroph...  
WO/2020/047129A1
A novel Low Free 2-MercaptoEthanol Ester has been used to prepare Alkyl Tin Reverse Ester Stabilizers as well as used to enhance the thermal performance of those Alkyl Tin Reverse Ester Stabilizers or Alkyl Tin Thioglycolate Stabilizers ...  
WO/2020/043747A1
The present invention relates to linker molecules of formula (1), X-Tb-Va-U-Y-Z (1) and a method for purifying peptides using said linker molecules. The linker molecule can be coupled to a purification resin via the moiety X and to a pep...  
WO/2020/036069A1
Provided are: a composition for forming a hole transporting layer for perovskite solar cells, which is inexpensive and does not need to be used together with a dopant; and a compound which can be contained in a composition for forming a ...  
WO/2020/035027A1
Provided are a linker represented by formula I or I', an antibody-drug conjugate including the same, a use thereof, a pharmaceutical composition including the antibody-drug conjugate, and a use of the antibody-drug conjugate in treating ...  
WO/2020/029720A1
Disclosed in the present invention is a method for preparing 2-chloro-6-methylthiotoluene. In the method, 2-chloro-6-aminotoluene and a sodium thiomethoxide aqueous solution are used as raw materials to generate 2-chloro-6-methylthiotolu...  
WO/2020/025789A1
The present invention relates to salts of elafibranor.  
WO/2020/018462A1
The invention provides a chromogenic β-lactam molecule that retains its diagnostic color change response when modified for conjugation to another molecule.  
WO/2020/017620A1
[Problem] To provide a labeled fatty acid derivative for imaging diagnosis that enables quantification of fatty acid metabolic activity in the heart muscle. [Solution] As the results of intensive studies on a method enabling quantificati...  
WO/2020/013190A1
Provided is a Brassica oleracea plant having a high S-methylmethionine content. The present invention pertains to a Brassica oleracea plant that contains S-methylmethionine at a higher concentration than existing Brassica oleracea plants...  
WO/2020/006229A1
The present application provides chemical compounds useful, for example, in inhibiting gasdermin pore formation in a cell, inhibiting inflammasome-mediated death of a cell (pyroptosis); inhibiting cytokine secretion from a cell, inhibiti...  
WO/2019/242889A1
The present invention relates to a novel process for the preparation of Vortioxetine and a key intermediate thereof by employing a novel one-pot organo-pseudocatalytic C-H activation approach via hypervalent iodine chemistry.  
WO/2019/243369A1
The present invention relates to compounds of formula (I) that are able to generate oct-2-en-4-one and thus to provide a long-lasting or substantive strawberry odor to the environment. Moreover, the present invention relates to a method ...  
WO/2019/232629A1
Chemical-based methods and products for mitigating the impact of an oil spill are disclosed. The products act by herding, thickening, gelling, and reducing adhesiveness. N-fatty acid amino acid (FA-AA) conjugates display oil-herding beha...  
WO/2019/235569A1
The present invention addresses the problem of providing: a novel kinase inhibitor and others; and a therapeutic agent for a disease, a drug discovery screening method and others, each utilizing the inhibitor and others. A compound repre...  
WO/2019/237117A1
The present invention, in one aspect, relates to monomers and photopolymers that exhibit a high refractive index. The photopolymers of the invention have properties suitable for fabricating holographic optical elements (HOEs).  
WO/2019/230653A1
The present invention provides a compound represented by formula (I): [symbols in the formula are as described in the specification].  
WO/2019/229625A1
The present invention relates to a process for the preparation of Apalutamide of formula (A) Apalutamide is a latest-generation androgen receptor inhibitor, used to treat non-metastatic castration-resistant prostate cancer.  
WO/2019/223290A1
Disclosed is a method for preparing thiourethane, comprising: esterifying a xanthate with 2-halogen ethanol to obtain an O-alkyl-S-hydroxy ethyl xanthate; and then performing an aminolysis reaction with a fatty amine to obtain a mixture ...  
WO/2019/222805A1
The disclosure relates to the synthesis of amide containing compounds in flow. In particular, the disclosure relates to the synthesis of polypeptides via native chemical ligation in flow. The disclosure also relates to selective desulfur...  
WO/2019/162911A8
This invention describes a class of compounds able to activate the human SIRT1 enzyme and regulate many metabolic functions. This invention relates to compounds that can be employed in medical applications, specifically for the treatment...  
WO/2019/223575A1
The present invention provides a method for preparing pentaerythritol ester, comprising the following steps: 1) adding 3-dodecane methyl mercaptopropionate and pentaerythritol in a molar ratio of (4.2-4.6):1, introducing nitrogen for pro...  
WO/2019/221192A1
The present invention provides a method for producing an amino acid aminoalkyl ester or an inorganic acid salt thereof by reacting a compound represented by general formula (I) or a compound represented by general formula (III), or a sal...  
WO/2019/219597A1
The following invention regards a process of demethylating a methyl ester of methionine or its hydroxy analog and producing methane thiol as a side-product. The methionine and its hydroxy analog are suitable as an animal feed additive an...  
WO/2019/219696A1
The invention relates to a method for producing 2,5-di(alkylthio)-α,α'-dibromo-p-xylenes of formula (3) below, in which R and R' are each selected independently from saturated, linear, branched or cyclic C1-C20 alkyl groups, comprising...  
WO/2019/219758A1
A process comprising the following steps: a-i) treating a polyunsaturated ester with a base in a solvent of lower alcohol and water to form the corresponding polyunsaturated acid; a-ii) treating the product from step a-i), especially the...  
WO/2019/216600A1
The present invention relates to an oxime ester group-substituted aromatic compound, a preparation method therefor, and a photoresist composition comprising same and is useful for providing a photosensitive composition, which effectively...  
WO/2019/211568A1
The subject of the invention is a process for the synthesis of fluorinated aromatic molecules of formula (I) Ar2-A-B (I) in which Ar2 represents a (hetero)aryl; A represents an atom from the 16th group of the periodic table; B represents...  
WO/2019/210742A1
The present invention relates to a novel acrylic ketone oxime ester compound, a preparation method therefor, and a composition thereof. The acrylic ketone oxime ester compound of the present invention can initiate the occurrence of a pol...  
WO/2019/205693A1
A process for preparing oxamyl is provided, the process comprising: a) providing a solution of oxamyl in a solvent system comprising a lower alcohol or a mixture of a lower alcohol and water; and b) precipitating oxamyl from the solution.  
WO/2019/208355A1
A method for producing a trifluoromethyl thioalkyl halide compound represented by formula (1) (wherein X1 represents a halogen atom selected from the group consisting of a fluorine atom, a chlorine atom, a bromine atom and an iodine atom...  
WO/2019/198598A1
Provided is a eugenol derivative that serves as a component of a polymer coating material that can be applied to various base materials regardless of the type thereof, to coat surfaces of the base materials in order to impart functionali...  
WO/2019/194982A1
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Moll usca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions co...  
WO/2019/189716A1
The present invention addresses the problem of providing a method for producing a fluorinated sulfide compound, particularly a sulfide compound containing hydrogen and fluorine, in a simple manner, at low cost and on an industrial scale....  
WO/2019/189761A1
Provided is a method for producing a polythiol compound, the method including reacting a halide represented by formula (1) with an alkali metal compound selected from the group consisting of alkali metal sulfides and alkali metal hydroxi...  
WO/2019/189787A1
In this method for producing an organic mercapto compound or an intermediate thereof, a method for producing a thioester compound comprises a reaction step for reacting an alcohol compound containing a sulfur atom with a thioamide compou...  
WO/2019/178699A1
The present description relates to glycoconjugates, glycoconjugate immunogens and glycoconjugate vaccines comprising carbohydrate antigens coupled to immunogenic carrier proteins, or materials used for detection and screening of resultin...  
WO/2019/181714A1
A compound according to the present invention is characterized by being represented by formula wherein: R1 represents an oxygen atom or a sulfur atom; and each of R2-R6 independently represents a hydrogen atom, an alkyl group having 1-6 ...  
WO/2019/178373A1
This invention relates to a phenolic resin composition comprising a phenolic resin admixed with and/or modified by one or more functionalized organosulfur compounds. This invention also relates to a rubber composition comprising (i) a na...  
WO/2019/178166A1
Provided herein are, inter alia, amphiphilic thiol compounds and methods of using the same for the purpose of depalmitoylating proteins in cellular membranes (e.g., plasma membranes). The compounds provided herein include an amphiphilic ...  
WO/2019/178381A1
This invention relates to a process of mixing a phenolic resin and one or more functionalized organosulfur compounds into a rubber composition comprising a rubber component. The interaction between the phenolic resin component and the fu...  

Matches 1 - 50 out of 19,879