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Matches 1 - 50 out of 19,610

Document Document Title
WO/2019/043604A1
The invention relates to peptide conjugates, methods for making peptide conjugates, conjugates produced by the methods, and pharmaceutical compositions comprising the conjugates. Methods of eliciting immune responses in a subject and met...  
WO/2019/025540A1
The invention relates to 3-acyl-benzamides of formula (I) as herbicides. In formula (I) X, Y, Z and Rx represent radicals such as alkyl, cycloalkyl and halogen.  
WO/2019/025017A1
The present invention relates to a process for the preparation of elafibranor and novel synthesis intermediates.  
WO/2019/026994A1
The present invention provides a pharmaceutical composition for the treatment or prevention of cognitive function diseases or disorders, wherein the pharmaceutical composition contains a compound represented by formula (I), an enantiomer...  
WO/2019/025498A1
The present invention relates to catechol-derivative compounds of formula (I), as well as polymeric compounds obtained by condensation. The present invention also relates to the use of the compounds for preparing functional coatings and ...  
WO/2019/018892A1
There is provided a range of novel disulfide bond containing compounds. These disulfide bond containing compounds can be used in a variety of applications such as solid phase peptide synthesis, solid phase organic synthesis, formation of...  
WO/2019/021758A1
With the purpose of the present invention being to provide a resist material having high coating film smoothness and uniformity, and excellent resolution or other patterning performance, a resist material is provided that contains a cali...  
WO/2019/017415A1
The present invention addresses the problem of providing a method for producing purified methionine, the method being capable of preventing the caking of methionine. The present invention pertains to a method for producing purified methi...  
WO/2019/016354A1
The invention relates to a novel amino acid having a norbornene group and polypeptide comprising the novel amino acid compounds. The invention also relates to a method of producing polypeptides comprising a norbornene group and to the us...  
WO/2019/013299A1
The present invention provides a thermally conductive material that has excellent thermal conductivity. The present invention also provides: a device that is provided with a thermally conductive layer that includes the thermally conducti...  
WO/2019/008156A1
The present invention provides novel compounds of formula (I) that are useful as inhibitors of the PD-1/PD-L1 protein/protein interaction. The compounds may be used in the treatment of cancer, infectious diseases and neurodegenerative di...  
WO/2019/001361A1
A piperic acid derivative and preparation and an application thereof. The structure of the derivative is as shown in general formula I. The compound of general formula I has excellent pesticidal, miticidal, and bactericidal activities an...  
WO/2018/233562A1
The present invention relates to an intermediate for preparing oseltamivir and an isomer thereof. The intermediate of the present invention is prepared by means of neighboring group participation at room temperature under the conditions ...  
WO/2018/229083A1
The present invention relates to compounds, in particular those of formula (I) and formula (II) described herein, or pharmaceutically acceptable salts or solvates thereof, which may be used as radioligands in in vitro, ex vivo and in viv...  
WO/2018/227840A1
The present application relates to a methionine production method for reducing by-product sodium sulfate, comprising: adding sodium carbonate or a mixture of sodium carbonate and sodium hydroxide into 5-(2-methylthioethyl)-hydantoin aque...  
WO/2018/227839A1
The present application relates to an environment-friendly production method for methionine, comprising: hydrolyzing 5-(2-methylthioethyl)-hydantoin with sodium carbonate, then performing sodium carbonate crystallization, performing soli...  
WO/2018/225790A1
The present application discloses a crystal of an oxidized glutathione dication salt and a production method for the crystal.  
WO/2018/215206A1
The present invention relates to a process for preparing methionine comprising the hydrolysis of 5-(2-methylmercaptoethyl)hydantoin (methionine hydantoin) in an alkaline process solution in which by-products comprising formate and other ...  
WO/2018/212149A1
The invention of the present application provides a pneumatic conveyance method for methionine that can suppress crush of methionine to a minimum, the method being characterized in that, when pneumatically conveying methionine using carr...  
WO/2018/210615A1
The present invention relates to a process for preparing methionine, comprising the alkaline hydrolysis of 5-(2-methylmercaptoethyl)-hydantoin (methionine hydantoin) in an aqueous process solution comprising alkali metal hydroxide and/or...  
WO/2018/208709A1
The present application discloses stilbene derivative compounds and compositions, and methods for treating ocular diseases, neurological disorders and protein aggregation-related disorders in patients using the compounds and compositions...  
WO/2018/199292A1
The invention of the present application provides a recovered-carbon-dioxide purifying method in which, by bringing a carbon dioxide gas containing at least 3-methylmercapto-propionaldehyde and acrolein into contact with activated carbon...  
WO/2018/199294A1
The present invention provides a methionine production method characterized by including: a step in which 5–[2–(methylthio) ethyl] imidazolidine–2,4–dione is hydrolyzed in the presence of an alkali compound and a reaction liquid ...  
WO/2018/199296A1
The present invention provides a methionine production method including: a reaction step (1) in which 5–[2–(methylthio) ethyl] imidazolidine–2,4–dione is hydrolyzed in the presence of an alkali compound and a reaction liquid that...  
WO/2018/199295A1
The present invention is a method for producing methionine which includes a crystallization step in which carbon dioxide is introduced into a liquid reaction mixture containing an alkali salt of methionine and obtained by hydrolyzing 5-[...  
WO/2018/191789A1
The invention relates to compounds of Formula (I) and methods for their preparation. Also described are pharmaceutical compositions comprising a compound of Formula (I) and their use in the treatment or prevention of conditions associate...  
WO/2018/188763A1
The present invention concerns a process for the preparation of firocoxib, i.e. 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylpheny l)-furan-2-one, comprising steps (a)-(g), wherein the process provides for step (d) of the react...  
WO/2018/183538A1
Disclosed herein, inter alia, are nucleotide analogues, and methods of use thereof, having cleavable orthogonal linkers.  
WO/2018/181986A1
The present invention provides a pharmaceutical composition for treating or preventing cognitive function disease or disorder, the composition comprising a compound represented by formula (I), an enantiomer thereof, a diastereomer thereo...  
WO/2018/177588A1
The invention relates to novel ester compounds based on bi-, tri- or higher functional carboxylic acids of general formula (I) and to a method for the production thereof and the use thereof in lubricants.  
WO/2018/167405A1
The invention concerns a method for manufacturing 2-hydroxy-4-(methylthio)butyric acid (HMTBA) from 2-hydroxy-4-(methylthio)butyronitrile (HMTBN), comprising the following steps: hydrolysing the HMTBN to HMTBA in the presence of a minera...  
WO/2018/162364A1
The present invention refers to a process for a catalytic aryl transfer to rearrange the backbone of aromatic C-X bonds.  
WO/2018/159650A1
The purpose of the present invention is to provide a compound which has a guanidine skeleton and inhibits the protease activity of MALT1 to exhibit a therapeutic effect or prophylactic effect on autoimmune diseases such as psoriasis. The...  
WO/2018/157232A1
Compositions comprising modulators of N-terminus activation of the androgen receptor, such as EPI-002 and EPI-506, and a second therapeutic agent are provided. Use of such compositions for treatment of various indications, including pros...  
WO/2018/151501A1
The present invention relates to a novel polyol or polythiol having three or more functional groups, a preparation method therefor, and an optical body manufactured therefrom. Especially, the present invention relates to a poly(thio)uret...  
WO/2018/148254A1
Provided herein are cysteamine or a pharmaceutically acceptable salt thereof and methods of using such for treating asthma (e.g. , moderate to severe persistent asthma) or reducing the risk of asthma occurrence.  
WO/2018/144717A1
The present invention is directed to novel pleuroniutilin antibiotic compounds, intermediates which are useful for making these novel amibioiic compounds aad related methods and pharmaceutical compositions for treating pathogens, especia...  
WO/2018/144717A8
The present invention is directed to novel pleuromutilin antibiotic compounds, intermediates which are useful for making these novel antibiotic compounds and related methods and pharmaceutical compositions for treating pathogens, especia...  
WO/2018/137874A1
The present invention relates to a multi-step process for the production of dihydrolipoic acid, which can particularly be carried out as a one-pot reaction and without isolation of intermediates.  
WO/2018/138400A3
The present invention relates to a high-yield method for the production of extracts enriched with organosulfur compounds of the S-alkenyl-L-cysteine and S-alkyl-L-cysteine type. Said compounds are obtained from plants of the genus Allium...  
WO/2018/139186A1
Provided is a curable composition which has excellent storage stability and suppresses the generation of residue in unexposed portions, and from which a cured film having an excellent pattern shape can be obtained. Also provided are: a c...  
WO/2018/133705A1
The present invention relates to crystal forms of GFT-505 and a preparation method and use thereof. The provided crystal forms of GFT-505, CS1, CS2, CS5, and CS6, have high purities, good stabilities, low hygroscopicities, good solubilit...  
WO/2018/129609A1
Compounds of formula (II) are useful in modulating voltage-gated sodium channel activity. Their preparation and use for reducing the severity of convulsant activity in a subject, for example in the treatment of epilepsy, is presented.  
WO/2018/122511A1
The invention relates to the field of organic polysulphides, more particularly to a method for synthetising functionalised organic polysulphides of formula (I): R2-X-(NR1R7)C*H-(CH2)n-Sa-(CH2)n-C*H(NR1R7)-X-R2, in which the various subst...  
WO/2018/124803A1
The present application relates to a method for preparing L-methionine crystals with improved bulk density. As the L-methionine crystals prepared according to the method for preparing L-methionine crystals of the present application may ...  
WO/2018/114640A1
The present invention relates to a method for preparing methionine or methionine salts. In particular, the invention describes the step of preparing 2-hydroxy-4-(methylthio)butyronitrile (MMP-CN) from 3-methylthiopropanal (MMP) and hydro...  
WO/2018/110406A1
[Problem] To provide a luminescent nanocrystal composite which is orderly dispersed in a polymer matrix easily and exhibits excellent dispersibility in a crosslinkable polymer matrix having a mesogen structure. [Solution] The present inv...  
WO/2018/101057A1
Provided are a compound useful as a mold release agent, a mold release agent containing same, a curable composition, and a nanoimprint lithography resin material. Specifically, the present invention provides: a calixarene compound with a...  
WO/2018/099203A1
The present invention describes a crystalline form of oxamyl of formula (I), a crystal preparation process, the analyses of the crystal through various analytical methods and using the crystalline form to prepare a stable agrochemical fo...  
WO/2018/100008A1
The present invention relates to a process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol comprising the following steps: a) the reaction of a solution of amifostine with a strong acid, to obtain a solution of 2-...  

Matches 1 - 50 out of 19,610