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Matches 1 - 50 out of 3,834

Document Document Title
WO/2020/165601A1
Methods are provided for the synthesis of a compound of formula (X). R2 is selected from -H, -C1-C4-alkyl,-C2-C4-alkenyl and C1-C4-aryl; R3 is selected from -C(O)H and -C(O)C1-C4-alkyl; and A is a pharmaceutically acceptable anion (e.g.a...  
WO/2020/147704A1
Disclosed is a method for synthesizing a S-(-)-benzoylmercapto-2-methylpropanoic acid compound, comprising hydrolyzing the S-(-)-3-acetylmercapto-2-methylpropanoic acid represented by formula (II) as a raw material in a reaction solvent ...  
WO/2020/142865A1
Disclosed in the present invention are a Benzamide compound, intermediates, a preparation method, and an application. The present invention provides a Benzamide compound as represented by formula I, and pharmaceutically acceptable salts,...  
WO/2020/129899A1
In order to provide a method for the economical and efficient industrial production of C-aryl hydroxy glycoxide derivatives, the present invention provides a method for producing a C-aryl hydroxy glycoxide derivative represented by formu...  
WO/2020/117608A1
Oxidized disulfide oil (ODSO) solvent compositions are derived from by-product disulfide oil (DSO) compounds produced as by-products from the generalized mercaptan oxidation (MEROX) processing of a refinery feedstock. The oxidized disulf...  
WO/2020/102348A1
Provided herein are compositions and methods for preparing albumin-targeting moieties that feature a thioamide linkage. Methods to use the albumin targeting molecules to generate drugs with improved in vivo pharmacodynamics and biodistri...  
WO/2020/059790A1
The the present invention addresses the problem of providing a DP receptor antagonist. Compounds represented by general formula (I): (in the formula, all of the symbols are as defined in the specification) and pharmacologically acceptabl...  
WO/2019/234651A1
A process is described for the preparation of thiadiazole derivatives and more specifically a new synthetic process of compounds having general formula (I) and intermediate compounds having general formula (XVI).  
WO/2019/222805A1
The disclosure relates to the synthesis of amide containing compounds in flow. In particular, the disclosure relates to the synthesis of polypeptides via native chemical ligation in flow. The disclosure also relates to selective desulfur...  
WO/2019/226925A1
Disclosed are cationic lipids which are compounds of Formula (I), (II), (III), (IV), (V), or (VI). Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal d...  
WO/2019/219758A1
A process comprising the following steps: a-i) treating a polyunsaturated ester with a base in a solvent of lower alcohol and water to form the corresponding polyunsaturated acid; a-ii) treating the product from step a-i), especially the...  
WO/2019/189787A1
In this method for producing an organic mercapto compound or an intermediate thereof, a method for producing a thioester compound comprises a reaction step for reacting an alcohol compound containing a sulfur atom with a thioamide compou...  
WO/2019/176079A1
[Problem] To provide a biodegradable compound that has a structure degraded in cells, a lipid particle comprising the biodegradable compound and a medicinal composition containing the lipid particle. [Solution] According to one embodimen...  
WO/2019/162806A1
Controlled radical initiators, reaction mixtures containing the controlled radical initiators and various ethylenically unsaturated monomers, polymeric materials formed from the reaction mixtures, crosslinkable compositions containing th...  
WO/2019/107533A1
The present invention provides a compound for suppressing cell transformation, the compound being represented by the following general formula (wherein n is 1 or 2; R1 is H, methoxy(-OCH3), or Cl; R2 is H, -OCH3, or Cl; R3 is H, -OCH3, C...  
WO/2019/097503A1
The present invention relates to the treatment of cancer using combination therapy comprising a dual modulator of Insulin Receptor Substrate (IRS) and signal transducer and activator of transcription 3 (Stat3), in combination with an ant...  
WO/2019/087580A1
[Problem] To provide: a novel alkanethioic acid derivative which is capable of imparting characteristic scent or flavor to cosmetics or to food and beverages; and a perfume composition that comprises the pertinent compound as an active i...  
WO/2019/046931A1
Compounds of general formula IA, IB and IC outlined below, including pharmaceutically acceptable salts, solvates and hydrates thereof. Such compounds and pharmaceutical compositions comprising them may be used in medical conditions invol...  
WO/2019/044478A1
The invention is an electroconductive substance comprising a complex containing a rubeanic acid ligand and a copper ion. The copper ion included in the complex comprises a copper (I) ion. In addition, this electroconductive substance is ...  
WO/2019/034468A1
Process for the preparation of a compound with at least one monothiocarbonate group by reacting: - a compound with at least one mercaptoalcohol group and - a dialkylcarbonate, in the presence of a catalyst wherein the catalyst is a salt ...  
WO/2018/234139A1
2-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]aryloxy](thio)a cetamides for combating phytopathogenic fungi The present invention relates the compounds of the formula I and their N-oxides and agriculturally acceptable salts thereof, and t...  
WO/2018/183261A1
The present invention relates to a compound of Formula (I): where ℗ R, R1, R2, R3, and Z are as described herein and to a process for preparing a compound of Formula (I). This invention also relates to a process for the synthesis of a ...  
WO/2018/128386A1
Disclosed is a method for synthesizing a gamma-nitro dithioester derivative compound (a γ-nitro dithioester compound). The gamma-nitro dithioester derivative compound may be synthesized by subjecting a nitroalkene compound having two ca...  
WO/2018/128383A1
Disclosed is a method for preparing a chiral alpha-hydroxy thioester compound. In order to prepare a chiral alpha-hydroxy thioester compound, an alpha-oxo-aldehyde compound and a thiol compound may be stereoselectively reacted with each ...  
WO/2018/075848A1
Provided herein are sulfated compounds that are useful as high refractive index monomers for optical and other applications and methods for producing the same. The sulfated compounds are liquid at room temperature and exhibit good miscib...  
WO/2018/052936A1
Provided herein are therapeutic acrylate compounds useful as medical adhesives, comprising a therapeutic agent covalently linked to a methacrylate or cyanoacrylate moiety. Adhesive compositions and kits, such as liquid sutures and bone c...  
WO/2018/009830A1
The present invention relates to a compound having the structure of formula (I), wherein R1, R2, R3, R4, R5, R6, and R7 are as described herein. The present invention also relates to a process for the preparation of a compound of formula...  
WO/2017/140754A1
A process for preparing aminothiol ester compounds and salts thereof. The present invention relates to a process for preparing compounds of formula (I), (I) comprising the following steps: a) reacting a compound of formula (II) with an i...  
WO/2017/129483A1
The invention relates to a novel hetero-diels-alder cross-linker, to methods for the production thereof and use thereof for reversibly crosslinked polymer systems.  
WO/2017/130679A1
Provided is a method with which it is possible to produce a high-purity thiocarbonyl compound via an industrially practicable production method by removing a sulfurizing agent-derived byproduct via a simple post-reaction purification met...  
WO/2017/104248A1
The purpose of the present invention is to provide a nitrone compound having excellent productivity of a modified polymer, a method for producing said compound, a modifier composition, a modified polymer and a method for producing said p...  
WO/2017/099531A1
The present invention relates to a novel phenolic acid derivative compound having whitening and antioxidative activities and a use thereof and, more specifically, to a compound represented by chemical formula (1) below, an isomer thereof...  
WO/2017/090581A1
According to the present invention, a method for producing a carboxylic acid thioester is provided, which comprises reacting a compound represented by formula (I) with a carboxylic acid and a thiol in the presence of a catalyst comprisin...  
WO/2017/060422A1
The present invention provides novel cell-permeable carboxylic acid-based metabolites and cell permeable precursors thereof aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic ...  
WO/2017/060420A1
The present invention provides novel cell-permeable fumarate acyl mercaptoethylamines (FAMs) which have cellular effects including induction of Nrf2 and inhibition of the NFkB pathway. These compounds have utility in medicine including t...  
WO/2017/060400A1
The present invention provides novel cell-permeable carboxylic acid- based metabolites and cell permeable precursors thereof aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic...  
WO/2017/056832A1
Provided is an active-light-sensitive or radiation-sensitive composition that contains (A) a compound having two or more of the structures represented by general formula (1), the compound not having an acid crosslinking group, and (B) a ...  
WO/2017/035570A1
This invention relates to a RAFT agent formula (I).  
WO/2017/033128A1
The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors and prodrugs thereof.  
WO/2017/011232A1
Non-cyclic amide or thioamide based ionic liquids and methods of making them are disclosed.  
WO/2016/182900A1
Process for converting a carboxamide to a thiocarboxamide includes reacting (a) a substrate that comprises a heteroatom-containing moiety and a carboxamide moiety with (b) a dialkyl dithiophosphate and/or a salt thereof. The heteroatom-c...  
WO/2016/161445A1
The present invention provides methods of forming hydrogen sulfide. The methods include contacting a precursor compound with an unmasking agent; wherein the precursor compound comprises a hydrogen sulfide releasing moiety and a masked nu...  
WO/2016/143876A1
Provided is a substance separation membrane (in particular, gas separation membrane) obtained using a ligand compound capable of producing the MOP. Also provided is a single-hole or multi-hole coordination polymer which comprises metal i...  
WO/2016/125169A1
The present invention relates to the treatment of cancer using combination therapy comprising a dual modulator of Insulin Receptor Substrate (IRS) and signal transducer and activator of transcription 3 (Stat3), in combination with (i) a ...  
WO/2016/116634A1
A process for the preparation of a polyunsaturated thiol comprising: (1) reacting a polyunsaturated alcohol in the presence of a compound of formula R2-SO2Hal wherein R2 is a C1-20 hydrocarbyl group, such an C1-10 alkyl group, to form a ...  
WO/2016/104317A1
The present invention addresses the problems of providing a polymerizable compound which, when added to a polymerizable composition, has high storage stability without causing any crystal precipitation, etc. and of providing a polymeriza...  
WO/2016/100694A1
The present invention relates generally to peroxyformic acid forming compositions, methods for forming peroxyformic acid, preferably in situ, using the peroxyformic acid forming compositions. The present invention also relates to the per...  
WO/2016/084870A1
Provided is an acylaminophenyl-group-containing compound having a neuroprotective effect. Also provided is a neuroprotective agent including an acylaminophenyl-group-containing compound. A novel acylaminophenyl-group-containing compound,...  
WO/2016/075085A1
The present invention relates to Fluoromalonyl Halfthioesters (F-MAHTs) of formula (I), wherein R1 represents hydrogen, halogen, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted...  
WO/2016/030790A1
Oxime sulfonate compounds of the formula (I), wherein R 1 is O(CO)R 4, COOR 5 or CONR 6R 7; n is 1 or 2; R 2 for example is C 1-C 8alkyl, C 3-C 6cycloalkyl or benzyl; R 3 is for example C 1-C 8alkyl, C 3-C 6cycloalkyl, C 1-C 8haloalkyl, ...  

Matches 1 - 50 out of 3,834