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Matches 1 - 50 out of 960

Document Document Title
WO/2018/058246A1
The present invention discloses a novel therapeutic axis NTPDase8 enzyme, Ρ2Υ6 and/or P2Y2 receptors, and provides methods, enzymes and/or antagonists for remedying inflammatory bowel diseases.  
WO/2017/208914A1
The present invention provides: a liquid crystal panel which is able to be driven at a low voltage, while achieving a wide color gamut, and which is suppressed in the production of residual DC due to ultraviolet light that is contained i...  
WO/2017/106007A1
A method of treating sour water from industrial processes such as coal gasification. The method includes injecting a polysulfide into a sour water stream to convert cyanide to thiocyanate, thereby reducing the corrosiveness and toxicity ...  
WO/2016/194813A1
The purpose of the present invention is to provide a new process for producing an enzalutamide crystal form which is reduced in the contents of 2-propanol and B-form crystals, the process including obtaining wet crystals of enzalutamide ...  
WO/2016/168059A1
This disclosure relates to the field of moiecuies having pesticida i utility against pests in Phyla Arthropoda, Moliusca, and hJematoda, processes to produce such moiecuies, intermediates used In such processes, pesticidai compositions c...  
WO/2016/168058A1
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...  
WO/2016/143634A1
Provided is a bimesogenic compound which exhibits high solubility in other bimesogenic compounds and substances used in conventional liquid crystal display elements, such as liquid crystalline compounds, liquid crystal compositions, chir...  
WO/2016/127873A1
The present invention provides an isothiocyanate compound and an application thereof. The compound is an aryl substituted isothiocyanate compound that has a structure in the general formula I. The isothiocyanate compound in the present i...  
WO/2016/071863A1
The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ri is selected from an SCN- group or is an RCONH- group; in particular, where Ri = RCONH, R is selected from an aromatic...  
WO/2016/014522A1
Disclosed are small molecule inhibitors of deubiquitinating enzymes (DUBs), and methods of using them. Certain compounds are selective for particular ubiquitin-specific proteases (USPs).  
WO/2014/167560A1
This invention provides pure methylene bis(thiocyanate) in an ecor industrial process. The product is practically free of insolubles (<0.1%) after prolonged storage.  
WO/2014/154117A1
An isothiocyanate having the following structural formula (I). The isothiocyanate synthesis processing technique is as follows: obtained by using conventional organic bases, carbon disulfide, and acetyl chloride to react in a low tempera...  
WO/2014/141082A1
The invention relates to a novel agent in the form of rhodanine derivatives, which has prophylactic, antiproliferative and antimetastatic activity. Said agent can find use in medicine and pharmacology for the prophylaxis and/or treatment...  
WO/2014/136690A1
The present invention pertains to: a production method for an isothiocyanate using an organic primary amine and thiourea as starting materials; a composition for transporting and storing a N-substituted O-substituted thiocarbamate, said ...  
WO/2014/058996A1
Provided herein are processes for the preparation of alkoxycarbonyl isothiocyanates from alkyl chloroformates and thiocyanates in toluene by controlling the amounts of water and catalyst.  
WO/2013/179057A1
The present invention relates to a method of synthesising sulforaphane by reacting a compound of formula (A) with an oxidizing agent in an aqueous solvent and in the presence of a catalyst. The invention further provides a method of synt...  
WO/2013/179056A1
The present invention relates to methods of isolating and purifying sulforaphane. More specifically, the present invention relates to methods of isolating and purifying sulforaphane from natural sources. The present invention also relate...  
WO/2013/157229A1
[Problem] The present invention provides an alkylphenylsulphide derivative having excellent pest control effect or a salt thereof, a pest control agent containing the same as an active component and a production intermediate thereof. [So...  
WO/2013/132124A1
The present invention relates to a new series of compounds having general formula (I) and the optical isomer or enantiomer forms thereof, which belong to the family of sulforaphane derivatives. The invention also relates to the productio...  
WO/2013/067646A1
The present application provides processes and intermediates useful in the production of β- aminocarbonyl- or β-aminothiocarbonyl-containing compounds. Provided herein is a process for synthesizing β-aminocarbonyl- or β-aminothiocarb...  
WO/2013/041204A1
The invention relates to novel isocyanate and isothiocyanate compounds, pharmaceutical compositions comprising same, and the use thereof for the treatment of cancer in humans and animals. Compared with previously known isocyanate and iso...  
WO/2013/031603A1
Provided are: a liquid-crystal compound that can combine characteristics such as chemical stability, excellent compatibility with other liquid-crystal materials or non-liquid-crystal materials, fast response, low viscosity, a wide liquid...  
WO/2012/158008A1
Sulforaphane is an isothiocyanate having anti-microbial and anti-carcinogenic properties, found in a broad range of vegetables of the Brassica oleracea genus, of which broccoli and cabbage are considered to be the most important types. T...  
WO/2012/146569A1
The invention relates to a method for producing 2-chloroallyl isothiocyanate from 2,3-dichloro-1-propene, wherein the 2,3-dichloro-1-propene is reacted with a thiocyanate in the presence of a phase-transfer catalyst, without diluent or i...  
WO/2012/073314A1
The purpose of the invention is to provide a novel production method for producing a corresponding isothiocyanate compound having a carboxyl group at high purity in one step by a reaction of an amino compound having a carboxyl group, thi...  
WO/2012/010644A1
Process for the synthesis of an isothiocyanate of general formula (I) SCN‑R1-R4-R2 in which R1 and R2 represent, independently of one another, an alkyl, aryl or alkylaryl group, R4 represents a carbonyl, sulphinyl or sulphonyl group or...  
WO/2011/073143A1
Substituted cyanobutyrates of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts...  
WO/2010/140902A1
The invention provides the use of isothiocyanate and isoselenocyanate compounds for treating diseases and conditions mediated by MIF.  
WO/2010/140271A1
Disclosed is a substance which can potentiate the power of α brain waves produced from the cerebrum of a human to exhibit a relaxing activity, an concentration-enhancing activity and an anti-stress activity. Specifically disclosed is a ...  
WO/2010/125414A1
The subject of the present invention is a novel process for the preparation of the [4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-thiazolo-2-y l]-[2-cyclopropyl-1-(3-fluoro-4-methylphenyl)-ethyl]-amine of formula (I) and the new interme...  
WO/2010/125414A8
The subject of the present invention is a novel process for the preparation of the [4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-thiazolo-2-y l]-[2-cyclopropyl-1-(3-fluoro-4-methylphenyl)-ethyl]-amine of formula (I) and the new interme...  
WO/2009/145816A2
A first aspect of the invention is a compound (sometimes also referred to herein as an "active agent" or "active compound") of Formula (I) or ( Ia): or a pharmaceutically acceptable salt or prodrug thereof. Compositions thereof and metho...  
WO/2009/145816A3
A first aspect of the invention is a compound (sometimes also referred to herein as an "active agent" or "active compound") of Formula (I) or ( Ia): or a pharmaceutically acceptable salt or prodrug thereof. Compositions thereof and metho...  
WO/2009/114409A3
New fluorination processes for introducing one or more fluorine atoms into target substrate compounds with arylsulfur halotetrafluorides are disclosed. Also disclosed are methods for preparation of arylsulfur trifluorides.  
WO/2009/107796A1
Disclosed is a novel method for producing a corresponding isothiocyanate compound having a carboxyl group from an amino compound having a carboxyl group. Specifically disclosed is a method for producing an isothiocyanate compound having ...  
WO/2009/073592A3
The present invention provides fluoroalkyl amines represented by the formula R1-Q-S(O)x-C(H),(CH3)r(CH2)z+(1-1)-NHR and fluoroalkyl isocyanates and isothiocyanates represented by the formula RrQ-S(O)x-C(H)l(CH3)r(CH2)Z+(1-1)-N=C=X1, wher...  
WO/2009/073592A2
The present invention provides fluoroalkyl amines represented by the formula R1-Q-S(O)x-C(H),(CH3)r(CH2)z+(1-1)-NHR and fluoroalkyl isocyanates and isothiocyanates represented by the formula RrQ-S(O)x-C(H)l(CH3)r(CH2)Z+(1-1)-N=C=X1, wher...  
WO/2009/030457A1
The invention relates to methods of using certain compounds of formula (I), (II) and (III) in the synthesis of an insecticide intermediate of formula (IV), wherein the substituents are as defined in claim 1, to processes for preparing th...  
WO/2008/009127A1
The present invention relates to derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) having improved anti-inflammatory properties useful in the treatment of inflammation, pain and fever. More particularly, NSAIDs are derivatize...  
WO/2008/008954A2
The present invention provides glucosinolate and isothiocyante compounds and related methods for synthesizing these compounds and analogs. In certain embodiments, these glucosinolate and isothiocyanate compounds are useful and chemopreve...  
WO/2008/008954A3
The present invention provides glucosinolate and isothiocyante compounds and related methods for synthesizing these compounds and analogs. In certain embodiments, these glucosinolate and isothiocyanate compounds are useful and chemopreve...  
WO/2007/122488A3
The present invention provides a process for [18F]-fluorination of biomolecules containing a primary amino group such as proteins and peptides and in particular of peptides. The invention further provides reagents for this process, in pa...  
WO/2007/122488A2
The present invention provides a process for [18F]-fluorination of biomolecules containing a primary amino group such as proteins and peptides and in particular of peptides. The invention further provides reagents for this process, in pa...  
WO/2007/121269A3
This invention concerns N-(ortho phenylaminoaryl), N'-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.  
WO/2007/082996A1
This invention concerns novel neutral labeling reactants. The novel reactants are deri- vatives of diethylenetriaminepentaacetic acid (DTPA) diamides, wherein a suitable group is linked to the molecule allowing introduction of the said n...  
WO/2007/026373A3
An improved process for the preparation of Rivastigmine is disclosed.  
WO/2007/009798A2
A process of producing a compound of formula (3), wherein R1 is a C1-5alkyl group, R2 is a halogen atom, a C1-5 alkyl group, a C2-5 alkenyl group, a C2-5 alkynyl group, a C1-5 alkyl group, a C1-5 alkoxy group, a nitro group, or a hydroxy...  
WO/2007/009798A3
A process of producing a compound of formula (3), wherein R1 is a C1-5alkyl group, R2 is a halogen atom, a C1-5 alkyl group, a C2-5 alkenyl group, a C2-5 alkynyl group, a C1-5 alkyl group, a C1-5 alkoxy group, a nitro group, or a hydroxy...  
WO/2006/029532A1
Nitrate esters and methods for mitigating neurodegeneration, affecting neuroprotection, affecting cognition enhancement, and/or preventing or mitigating tissue and/or cellular damage in a subject are described. Neurological or cognitive ...  
WO2005112915A3
The present invention provides compositions, methods, and kits for reducing oxidative stress thereby extending life span. The compositions, methods, and kits of the present invention can also be used to treat diseases of aging resulting ...  

Matches 1 - 50 out of 960