| Document |
Document Title |
|
JP6806981B2 |
Provided herein are a use of thioether compounds of formula I as nitrification inhibitors, and agricultural mixtures and compositions including the thioether compounds.
|
|
JP2020504103A |
The present invention is suitable for kit formulation of highly sensitive and heat sensitive targeting molecules under mild reaction conditions [99mRegarding labeling procedures for incorporation into Tc (N) (PNP)] compounds. [Selection ...
|
|
JP6619348B2 |
In one embodiment, the present application discloses compounds that are selective neuroactive agents for the treatment of diseases of the central nervous system (CNS). In one aspect, the neuroactive agents are NCDs of metal chelates, inc...
|
|
JP6609634B2 |
The invention relates to hydrosoluble hydroxybisphosphonic derivatives of doxorubicin of formula (I) and the pharmaceutically acceptable salts thereof. The invention also relates to the use of said compounds as a drug, especially in the ...
|
|
JP6587648B2 |
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.
|
|
JP2019512009A |
The present invention is based on the formula (I)With respect to the compounds of, as well as pharmaceutically acceptable salts, solvates, and prodrugs, in formula (I), Q is selected from O, S, and Se, and J is S or Se. W1And W2Is indepe...
|
|
JP6297674B2 |
The invention provides compounds of Formula I, and methods of treating or preventing a bacterial infection in a subject using a compound of Formula I. The invention also provides the use of a compound of Formula I in the manufacture of a...
|
|
JP6245481B2 |
The present invention relates to a novel composition useful in targeted diagnostic and/or therapy of a target site, such as cancerous tissue. The composition and methods disclosed herein find particular use in diagnosing and imaging canc...
|
|
JP6231548B2 |
This invention is directed to compound of Formula I and methods of using these compounds in the treatment of conditions in which modulation of a cathepsin, particularly cathepsin K or cathepsin L, will be therapeutically useful.
|
|
JP2017518312A |
The pharmaceutical composition may comprise a malmerin analog compound and a pharmaceutically acceptable carrier with the compound. The compound may be present in a therapeutically effective amount for treating or inhibiting the conditio...
|
|
JP6037396B2 |
A novel serine racemase inhibitor exhibits sufficient activity and specificity. The serine racemase inhibitor includes one or more compounds selected from compounds respectively represented by the following general formulas [MM_1], [DR_1...
|
|
JP2016020311A |
To provide a vinyl compound having both stability and reactivity.The present invention relates to a compound represented by formula (1).SELECTED DRAWING: None
|
|
JP2016020312A |
To provide a bifunctional vinyl compound having a polymerizable functional group, wherein the compound has both stability and reactivity and therefore can be used as an easy-to-handle resin crosslinking agent.The present invention relate...
|
|
JP2015134798A |
To provide a method of making asymmetrical bis(thiosemicarbazones), compounds useful as synthetic intermediates in the method, new bis(thiosemicarbazones) that can be readily accessed by use of the method, and methods of treatment and im...
|
|
JP5711142B2 |
The present invention relates to a method of making asymmetrical bis(thiosemicarbazones), compounds useful as synthetic intermediates in the method, new bis(thiosemicarbazones) that can be readily accessed by use of the method and method...
|
|
JP5631327B2 |
The present invention is directed to compounds represented by structural formula (I), or a pharmaceutically acceptable salt or a transition metal chelate, coordinate or complex thereof or a transition metal chelate, coordinate or complex...
|
|
JPWO2012105438A1 |
The electrode active material has a dithionic structure as shown in the following general formula. In the dithion structure, the linking group Z is interposed between the X = S groups (X: C or Si). Connecting group Z is CH2, CF2, O, S, S...
|
|
JP5277213B2 |
Antibacterial compounds of formula (I) are provided: As well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; treating bacterial infections by the a...
|
|
JP5117377B2 |
Chemical compounds identified by in silico molecular modelling, and having an structure that allows the blocking of the phosphorylation event, through the interaction of such compounds with the phosphorylation domain or its milieu in the...
|
|
JP5093429B2 |
Ectoparasitic insect pest controllers for animals, containing hydrazine derivatives of the general formula (I) as the active ingredient, and methods for application of the same: (I) Äwherein A is (II), (III), (IV), (V) (wherein R<4> and...
|
|
JP5086635B2 |
Antibacterial compounds of formula (I) are provided: As well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; treating bacterial infections by the a...
|
|
JP4965428B2 |
It is intended to provide a novel free radical scavenger for removing active oxygen which is causative for various diseases in vivo and results in degradation and color fade-out in commercial products. A free radical scavenger which cont...
|
|
JP4939216B2 |
The invention provides novel compounds according to formula I relates to compounds with the general formula I said compounds being useful, e.g. in the treatment of inflammatory, ophthalmic diseases or cancer.
|
|
JP2011516499A |
Provided herein are divalent hydrazide-polyethylene glycol conjugates that inhibit the ion transport activity of a cystic fibrosis transmembrane conductance regulator (CFTR). The conjugates described herein are useful for treating diseas...
|
|
JP2011516499T |
The 2 value hydrazide polyethylene-glycols conjugate which checks the ion transport activity of a cystic fibrosis membrane conductance control agent (CFTR) is provided. The conjugate indicated in this specification is useful in order to ...
|
|
JP4533471B2 |
|
|
JP2010522197A |
This invention is directed to compounds of formula (I): wherein m, n, R1, R2 and R3 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug the...
|
|
JP4478157B2 |
A compound represented by the following general formula (1) or a salt thereof or a hydrate of the foregoing is safe while exhibiting suitable physicochemical stability, and is useful as therapeutic or prophylactic agents for diseases ass...
|
|
JP2010501560A |
Disclosed are compounds and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70 induction and/or natural killer inductio...
|
|
JP4200936B2 |
To provide a new diazodisulfone compound having high sensitivity to far ultraviolet rays, particularly represented by KrF excimer laser or ArF excimer laser and capable of providing a chemical amplification type resist excellent in line ...
|
|
JP4091983B2 |
The subject of the invention is the products of formula (I):in which R1, R2, R3, R4, R5 and G are as defined in the description, the dotted lines represent an optional second bond, as well as the addition salts with acids and bases and t...
|
|
JP4028174B2 |
According to a novel process, it is possible to prepare triazolinethione derivatives of the formulain whichR1 and R2 are each as defined in the description bya) reacting hydrazine derivatives of the formulaor their acid addition salts wi...
|
|
JP3938991B2 |
To enable easy and high-yield production of the subject compound which is useful as a synthetic intermediate for other compounds such as thiazole or the like by allowing methyl bromide to react with a reaction product from carbon disulfi...
|
|
JP3808121B2 |
PURPOSE: To obtain the subject diagnostic having containing transfer to a target tissue, affinity for reduction reaction in the tissue, stability in a non-target tissue and rapid disappearance from the nontarget tissue, containing a radi...
|
|
JP2006515274A |
Methods for regulation of lipid and cholesterol uptake are described which are based on regulation of the expression or function of the SR-BI HDL receptor. The examples demonstrate that estrogen dramatically downregulates SR-BI under con...
|
|
JP2005320549A |
To provide a new material which promotes the polymerization of a monomer in a living-type free radical polymerization and to provide a polymerization process using it.In this process, a mixture comprising at least one monomer, at least o...
|
|
JP3711581B2 |
PURPOSE: To obtain a new semicarbazone derivative, having excellent insecticidal and acaricidal activities against agricultural insect pests and tetranychids in a small dose, hardly exerting adverse influences upon mammals, fishes and be...
|
|
JP3712619B2 |
The present invention provides novel cathecol hydrazone derivatives of formula (I) or pharmaceutically acceptable salts thereof, wherein R1 is C1-7 alkyl or C3-7 cycloalkyl; R2 is hydrogen, hydroxy, C1-5 alkyl or -CH2CH2C(=O)NH2; R3 and ...
|
|
JP3696203B2 |
A method of free radical polymerization and for cleaving a thio group from the resulting polymer is provided. The method comprises forming a mixture of one or more monomers, at least one free radical source and a control agent, wherein t...
|
|
JP2005506299A |
Compounds of this invention are non-peptide, reversible inhibitors of type 2 methionine aminopeptidase, useful in treating conditions mediated by angiogenesis, such as cancer, haemangioma, proliferative retinopathy, rheumatoid arthritis,...
|
|
JP2004536795A |
A process is provided for producing a thiosemicarbazide which includes the steps of reacting an alkylamine with carbon disulphide in the presence of a base selected from N,N-diisopropylethylamine and N,N,-diisopropyl-methylamine to produ...
|
|
JP3596032B2 |
|
|
JP2004534779A |
The present invention is directed in part towards methods of modulating the function of protein kinases with phenol- and hydroxynaphthalene-based compounds. The methods incorporate cells that express a protein kinase. In addition, the in...
|
|
JP2004534808A |
The invention relates to a novel class of ligands, complexes comprising such ligands and a metal ion, and adducts of these metal complexes and a macromolecule. Pharmaceutical compositions and methods of making and using the ligand-metal ...
|
|
JP2004532187A |
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invent...
|
|
JP2004523490A |
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins. In the compounds of this invention, at least two carbo- or heterocyclic groups are attached...
|
|
JP2004520302A |
Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected substituted thi...
|
|
JP3525457B2 |
PURPOSE: To obtain a new benzalacetophenone-4-phenylsemicarbazone derivative capable of manifesting excellent insecticidal activities in a low dose with hardly any adverse effects on mammals, fishes and beneficial insects. CONSTITUTION: ...
|
|
JP3498331B2 |
PURPOSE: To provide a useful noxious life controlling agent having excellent insecticidal and miticidal activities against a number of agricultural insect pests and spider mites and giving little influence on mammal, fish and beneficial ...
|
|
JP3498372B2 |
PURPOSE: To obtain a new semicarbazone compound useful as a noxious organism-controlling agent, having excellent insecticidal or germicidal activity at low doses, land having little adverse effects on mammals, fish and beneficial insects...
|
