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WO/2012/018757 |
The present invention discloses processes for forming polythiol compositions from olefinic hydrocarbons such as cyclooctadiene, cyclododecatriene, and trivinylcyclohexane. The polythiol compositions produced from these processes, includi...
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WO/2011/026193 |
The present invention relates to a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof. In particular, the present invention relates to a method treating diseases involving cell proliferation, migr...
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WO/2011/026193 |
The present invention relates to a compound of general formula (I) or a pharmaceutically acceptable salt or solvate or thereof. In particular, the present invention relates to a method treating diseases involving cell proliferation, migr...
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WO/2010/066010 |
The present invention relates to a method of making asymmetrical bis(thiosemicarbazones), compounds useful as synthetic intermediates in the method, new bis(thiosemicarbazones) that can be readily accessed by use of the method and method...
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WO/2009/096039 |
A compound useful as an intermediate for obtaining a thiadiazole-based acaricide having a high purity in a high yield. This intermediate is obtained, for example, by reacting a 2-(4-hydroxyphenoxy)propionic acid ester represented by the ...
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WO/2008/025941 |
The invention provides metal complexes of formula (I), wherein M is a transition metal or a p-block metal, and a, b, c, n, L, X, X', Y, Y', L1, L1', R1, R1', R2 and R2' are defined herein. Such complexes are useful in medical imaging and...
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WO/2008/025941 |
The invention provides metal complexes of formula (I), wherein M is a transition metal or a p-block metal, and a, b, c, n, L, X, X', Y, Y', L1, L1', R1, R1', R2 and R2' are defined herein. Such complexes are useful in medical imaging and...
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WO/2008/024304 |
Disclosed are compounds of formula (IA), formula (IV) or formula (V), wherein the variables are as defined herein, and pharmaceutical compositions containing them which are useful for treating a subject with a proliferative disorder, suc...
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WO/2008/024304 |
Disclosed are compounds of formula (IA), formula (IV) or formula (V), wherein the variables are as defined herein, and pharmaceutical compositions containing them which are useful for treating a subject with a proliferative disorder, suc...
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WO/2008/024303 |
Disclosed are compounds of formulae (I), (III), (IV), (VII), (X), (XI), (XII), (XIII) and (XIV), wherein the variabables are as defined in the claims, and methods of using compounds of the invention for treating a subject with a prolifer...
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WO/2007/088545 |
The present invention provides a novel montelukast intermediate and a simple and straightforward process for preparing it. According to the present invention, by using this intermediate and the process, essentially as described herein, m...
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WO/2006/116816 |
The present invention relates to a storage stable dithizone preparation, whereby the dithizone preparation is in a form that is ready for use to detect the presence of transition metal ions in a sample. The present invention also relates...
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WO/2006/093124 |
It is intended to provide a novel free radical scavenger for removing active oxygen which is causative for various diseases in vivo and results in degradation and color fade-out in commercial products. A free radical scavenger which cont...
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WO/2006/041119 |
Compounds represented by the general formula (1) or salts thereof, or hydrates of both, which are safe and have moderate physicochemical stability and which are useful as preventive or therapeutic agents for diseases caused by thrombus f...
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WO/2006/019955 |
Disclosed herein are antiviral compounds, such as anti-human cytomegalovirus antiviral compounds, pharmaceutical compositions and antiviral methods.
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WO/2005/087211 |
The present invention provides a novel class of compounds that disrupt the parasitic infectious life cycle and serve as promising agents for anti-parasitic therapy.
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WO/2005/009940 |
The invention provides novel compounds according to formula I relates to compounds with the general formula I said compounds being useful, e.g. in the treatment of inflammatory, ophthalmic diseases or cancer.
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WO/2004/062601 |
Antibacterial compounds of formula (I) are provided: As well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infectio...
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WO/2003/078386 |
The present invention relates to novel naphthyl semicarbazone, naphthylhydrazone, naphthyl thiosemicarbazone, and naphthyl thiohydrazone compounds. The invention also relates to therapeutic uses of such compounds and&sol or their iron co...
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WO/2003/000647 |
The invention relates to a novel class of ligands, complexes comprising such ligands and a metal ion, and adducts of these metal complexes and a macromolecule. Pharmaceutical compositions and methods of making and using the ligand-metal ...
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WO/2002/098420 |
The present invention is directed to optionally substituted 4-substituted-1-(arylmethylidene)thiosemicarbazide, 4-substituted-1-(arylcarbonyl)thiosemicarbazide and analogs thereof, represented by the Formulae (I) and (II), wherein A¿1,?...
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WO/2002/096867 |
The present invention is directed in part towards methods of modulating the function of protein kinases with phenol- and hydroxynaphthalene-based compounds. The methods incorporate cells that express a protein kinase. In addition, the in...
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WO/2002/092019 |
Halogenated derivatives of two synthetic anti-tuberculosis agents, thioacetazone and $i(p)-aminosalicylic acid, have been synthesized. In general, the halogenated compound has the structure of Structure (I), wherein X¿1? is a halogen an...
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WO/2002/081438 |
A process is provided for producing a thiosemicarbazide which includes the steps of reacting an alkylamine with carbon disulphide in the presence of a base selected from N,N-diisopropylethylamine and N,N,-diisopropyl-methylamine to produ...
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WO/2002/078696 |
Compounds of this invention are non-peptide, reversible inhibitors of type (2) methionine aminopeptidase, useful in treating conditions mediated by angiogenesis, such as cancer, haemangioma proliferative retinopathy, rheumatoid arthritis...
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WO/2002/059080 |
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invent...
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WO/2002/049413 |
Invented are non-peptide TPO mimetics. also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected substituted thi...
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WO/2002/044126 |
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins. In the compounds of this invention, at least two carbo-or heterocyclic groups are attached ...
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WO/2002/042254 |
The present invention relates to a process of producing carbonyl a-substituted nitrogen-containing compounds, which comprises reacting a-halo-ketone or a-halo-aldehyde with primary amine, secondary amine or heterocycle compound containin...
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WO/2002/032226 |
Ectoparasitic insect pest controllers for animals, containing hydrazine derivatives of the general formula (I) as the active ingredient, and methods for application of the same: (I) [wherein A is (II) (III) (IV) (V) (wherein R?4¿ and R?...
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WO/2002/026836 |
Control agents that have a nitrogen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers. These control agents provide superior properties for con...
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WO/2000/073280 |
The present invention provides novel cathecol hydrazone derivatives of formula (I) or pharmaceutically acceptable salts thereof, wherein R?1¿ is C¿1-7? alkyl or C¿3-7? cycloalkyl; R?2¿ is hydrogen, hydroxy, C¿1-5? alkyl or -CH¿2?CH...
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WO/2000/034237 |
Compounds of formula (I) wherein R¿1?-R¿5? are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to ...
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WO/2000/005202 |
A method of preparing a compound of formula (I) where R?1¿, R?2¿, R?3¿, R?4¿ and R?5¿ are independently selected from hydrogen or specified substitutents, X is -O-, -S-, -NR?7¿-, -C=N-, -C=N-O-, -NR?8¿-NR?9¿-, where R?7¿, R?8¿ ...
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WO/2000/001700 |
The invention relates to a method for producing anellated triazoles, according to which substituted N-aminoureas are reacted with formaldehyde or paraformaldehyde to obtain the corresponding methylene-imine compounds and these are then c...
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WO/1999/067209 |
There is disclosed a process for preparing compounds of formula (I) comprising reacting a compound of formula (II): R-X-H, under basic conditions, with a compound of formula (III), wherein X is oxygen or sulfur; Y is alkyl, alkenyl, alky...
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WO/1999/025682 |
Compounds of this invention increase plasma levels of high density lipoprotein or HDL, the 'good' cholesterol and as such may be useful for treating diseases such as atherosclerosis. These compounds are represented by formula (A), wherei...
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WO/1999/023066 |
A compound of formula (I) wherein X is O or NH; Y is CH or N; W is methyl or methoxy; R?1¿ and R?6¿, which may be the same or different, are alkyl, alkenyl, alkynyl, carbocyclyl or heterocyclyl each of which may be substituted; R?2¿ a...
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WO/1999/018088 |
The invention relates to a novel method for producing triazolinthion derivatives of formula (I) in which R?1¿ and R?2¿ have the meanings given in the description. To this end, a) Hydrazine derivatives of formula (II) or addition salts ...
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WO/1998/057925 |
This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of formula (I) wherein: R?1�, R?2�, and R?3� are independently hydrogen, C�1?-C�6? alkyl or -(C...
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WO/1998/057926 |
This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of formula (I), wherein: R?1�, R?2� and R?3� are independently hydrogen, C�1?-C�6? alkyl or -(C...
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WO/1998/057927 |
This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of formula (I), wherein R?1�, R?2�, and R?3� are independently hydrogen, C�1?-C�6? alkyl or -(C...
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WO/1998/057928 |
This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of formula (I), wherein R?1�, R?2� and R?3� are independently hydrogen, C�1?-C�10? alkyl, or -(...
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WO/1998/057929 |
This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of formula (I) wherein : R?1�, R?2�, and R?3� are independently hydrogen, C�1?-C�6? alkyl or -(...
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WO/1998/050352 |
The invention relates to compounds of general formula (I), wherein X is O or NH; Y is CH or N; W is methyl or methoxy; R?1� and R?2�, which may be the same or different, are optionally substituted alkyl, optionally substituted alkeny...
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WO/1998/031659 |
The invention relates to imine derivatives of the madurahydroxylacton (3,9,11,14,15-pentahydroxy-7-methoxy-10-methyl-1,8,13-trioxo
-1,3,5,6,8,13-hexahydronaphthaceno[1,2-f]isobenezofuran), with formula (I), and their pharmaceutically acc...
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WO/1998/017267 |
Compounds containing two aromatic systems covalently linked through a linker containing one or more atoms, or 'linker' defined as including a covalent bond $i(per se) so as to space the aromatic systems at a distance 1.5-15�, are effec...
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WO/1998/015512 |
The invention concerns fungicidal compounds, and compositions containing them, of general formula (I) in which G is selected from the groups G1 to G9: (a) in which the different symbols represent various organic groups. The invention als...
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WO/1997/034865 |
Compounds of formula (I), wherein R1, R2, R3, R4, R5 and G are as defined in the description and the dotted lines indicate an optional second bond, as well as the acid, base and ester addition salts thereof, a method for preparing said c...
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WO/1997/022579 |
A process for producing a hydrazide of formula (1.0) is disclosed. The process comprises reacting a hydrazone of formula (2.0) or (2.1), wherein said hydrazone is in toluene, with a mixture of Grignard reagents, wherein said Grignard rea...
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