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Matches 1 - 50 out of 19,116

Document Document Title
WO/2019/129815A1
The invention provides a method for synthesizing a compound of formula (I) wherein each R independently represents an optionally substituted aryl, heteroaryl, alkyl, perfluoroalkyl, cycloalkyl, alkoxy, aryloxy, acyl, carboxyl, hydroxyl, ...  
WO/2019/121134A1
The present invention relates to the manufacturing of a process of alkyl 2- acetyl-5,9,13-trimethyltetradeca-4,8,12-trienoates and alkyl 2-acetyl-9,13-di- methyl-5-methylenetetradeca-8,12-dienoate as well as 6,10,14-trimethylpenta- deca-...  
WO/2019/121379A1
The present invention relates to the improved synthesis of chlorinated acetophenones (CAP) of formula (I). Particularly, the invention shows a way how to reduce the use of chlorinated solvents and the formation of chlorinated volatile by...  
WO/2019/118862A1
Devices, systems, and methods for forming furan based surfactants by reactive distillation are disclosed herein. Various embodiments can provide a consolidated reaction process that uses reactive distillation to synthesize oleo-furan sur...  
WO/2019/113050A1
Disclosed herein are methods useful for detecting and/or quantifying tropolone in samples, e.g., generated during the production of and in final formulations of a product, e.g., a recombinant protein, e.g., an antibody. Tropolone and der...  
WO/2019/110493A1
An allylic oxidation process comprising: forming a mixture containing α-Guaiene and an iron (III)-X porphyrin complex catalyst in a sustainable solvent, introducing molecular oxygen into the mixture, and effecting allylic oxidation to p...  
WO/2019/110299A1
Proposed is a process for producing rotundone from α-guaiene, in particular by oxidation of the C(3) position, wherein the α-guaiene is produced from a precursor by a sesquiterpene synthase. The sesquiterpene synthase is produced in a ...  
WO/2019/113383A1
The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated dis...  
WO/2019/113312A1
The present invention relates to a process for preparing compound 1 that useful as an anticancer agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.  
WO/2019/108773A1
The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFκB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and makes them par...  
WO/2018/094122A8
The present invention provides methods and compositions for treating atopic dermatitis by cyclohexenone compounds.  
WO/2019/107078A1
According to the present invention, a ketol compound is obtained in a high yield, high purity, and high efficiency without using an excessive amount of acetone. This method for preparing a ketol compound includes: a. a step for continuou...  
WO/2019/101813A1
The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to malodor counteracting compositions and/or ingredients, methods for counteracting malodors, as well a...  
WO/2019/103155A1
Provided is a highly photostable europium complex. The europium complex is represented by formula (A): [in the formula, RA and RB are each independently a C3-10 cycloalkyl group and RC is a C3-10 cycloalkyl group or a phenyl group repres...  
WO/2019/097542A1
A detailed examination of collision cross sections (CCSs) coupled with computational methods has revealed new insights into some of the key questions centered around curcumin, one of the most intensively studied natural therapeutic agent...  
WO/2019/096860A1
The present invention relates to a process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides by reacting (a) cyclopropylcarbonitrile to a cyclopropylcarbaldehyde, (b) further reacting t...  
WO/2019/091792A1
The present invention relates to a process for preparing methyl isobutyl ketone starting from acetone, wherein a raw product stream of methyl isobutyl ketone, for preparation, is firstly fed to at least one first distillation column (23)...  
WO/2019/092495A1
Methods may include obtaining ketones and glycols from a fermentation process, the method including: collecting an off-gas and/or a fermented broth from the fermenter, wherein the off-gas comprises a ketone, and wherein the fermented bro...  
WO/2019/036349A8
This invention discloses the first example of palladium(ll)-catalyzed β-C(sp3)-H iodination or arylation of a wide range of ketones by using a commercially available aminooxyacetic acid auxiliary. This L, X-type directing group overcome...  
WO/2019/086583A1
The invention relates to recombinant microorganisms and methods for producing macrocyclic ketones and macrocyclic ketone precursors.  
WO/2019/081009A1
A method for producing unsaturated macrocyclic monoketones comprising the following steps: (a) preparing macrocyclic dienes with a ring size of at least 9 carbon atoms; (b) contacting the starting materials from step (a) with (b1) a pall...  
WO/2019/080682A1
The present invention relates to the field of pharmaceutical synthesis, and relates to a method for the synthesis of 1,7-di-(4-hydroxyphenyl)-heptane-1,4-dien-3-one. A method for synthesizing 1,7-di-(4-hydroxyphenyl)-heptane-1,4-dien-3-o...  
WO/2019/076933A1
The present invention relates to new classes of odorous ketones (odorants) which are useful as fragrance or flavor materials in particular in providing coniferous, thuya, floral and/or fruity olfactory notes to perfume, aroma or deodoriz...  
WO/2019/076926A1
The present invention relates to new classes of odorous oximes and their ketone intermediates (odorants) which are useful as fragrance or flavor materials in particular in providing cassis, catty, tropical, green, coniferous, thuya, flor...  
WO/2019/076588A1
The present invention relates to fragrance storage substances of fragrant ketones, which are suitable, for example, for perfuming laundry, washing and cleaning agents, since they release the respective ketones during cleavage.  
WO/2019/067276A1
A method comprising synthesizing a cyclic organic compound (3) via reaction of an unsubstituted or substituted alkene (1) with an unsubstituted or substituted acrylic acid (2) in the presence of a sulfonic acid reagent to make the cyclic...  
WO/2019/067272A1
A method comprising synthesizing a cyclic organic compound via reaction of an unsubstituted or substituted cyclopentene with an unsubstituted or substituted acrylic acid in the presence of phosphoric and/or sulfonic acid reagent to make ...  
WO/2019/062561A1
Provided herein the synthesis methods of firocoxib and an intermediate thereof. The synthesis of the first intermediate is performed through methylation of p-bromopropiophenone or through Friedel-Crafts acylation of bromobenzene, avoidin...  
WO/2019/060188A1
The present teachings disclose contacting an amine salt catalyst with a dicarbonyl compound having an alkylene group between the carbonyl group; adding formaldehyde, paraformaldehyde, or formalin in an amount of about 2:1 to about 3:1 mo...  
WO/2019/059337A1
The present invention provides an efficient method for producing nootkatone via a biological method. More specifically, the present invention provides a nootkatone production method including converting nootkatole to nootkatone in the pr...  
WO/2019/052236A1
The present invention pertains to the field of fine chemicals and related chemical technologies and provides a preparation method for a butadiene derivative. Phenylacetylene and derivatives thereof are used as raw materials and react in ...  
WO/2019/051627A1
The present invention relates to a fluorogenic probe for detecting a polyazole heterocyclic compound and a preparation method therefor, relating to the technical field of fluorescent chemical sensors. The fluorogenic probe is prepared fr...  
WO/2019/051222A1
The present disclosure provides a benzene fused heterocyclic derivative of Formula (I): --̅-̅-̅ is a single or double bond; n is an integer of 0 or 1; A is -CH2-, -CH(OH)-, or - C(O)-; G is C or N; X is -CH2-, O, or -C(O)-; Y is alkyl...  
WO/2019/051038A1
Processes for making bicyclic compounds and precursors thereof, and particularly for making [1.1.1]propellane and bicyclo[1.1.1]pentane and derivatives thereof, utilize continuous flow reaction methods and conditions. A continuous proces...  
WO/2019/043251A1
The present invention relates to novel compounds which are particularly useful for the synthesis of novel chromanol derivatives. These compounds have interesting properties. Particularly, the novel chromanol derivatives have interesting ...  
WO/2019/042520A1
The invention relates to a method for producing terpene aldehydes and terpene ketones by oxidatively dehydrogenating the corresponding terpene alcohols, comprising or consisting of the following steps: (a) providing terpene alcohols or t...  
WO/2019/044914A1
The present invention addresses the problem of providing a drug solution purification method with which it is possible to obtain a drug solution exhibiting excellent impairment suppression performance. The present invention also addresse...  
WO/2019/040570A1
A method of reducing the salt content of a neutralized aralkyl hydroperoxide cleavage mass stream comprising passing the neutralized stream into a vessel, the vessel having an inlet, two outlets, an aqueous layer and a hydrocarbon layer ...  
WO/2019/036349A1
This invention discloses the first example of palladium(ll)-catalyzed β-C(sp3)-H iodination or arylation of a wide range of ketones by using a commercially available aminooxyacetic acid auxiliary. This L, X-type directing group overcome...  
WO/2019/025535A1
The present invention in general relates to a method for the deacylation and/or dealkylation (both O-dealkylation as well as C-dealkylation) of compounds, more specifically of aromatic compounds. The method is characterized by contacting...  
WO/2019/025579A1
The invention concerns a method for the manufacture of polyether ketone ketone (PEKK), comprising the step consisting in: (i) Providing a 1,4-bis(4-phenoxybenzoyl)benzene-Lewis acid complex; (ii) Purifying said 1,4-bis(4-phenoxybenzoyl)b...  
WO/2019/021889A1
A purpose of the present invention is to provide a method for efficiently producing a fluorophenol derivative in high yield. Such problem can be solved with the method of the present invention for producing a compound represented by form...  
WO/2019/022556A1
The present invention relates to a novel benzylideneacetone derivative or a use thereof and, more particularly, to a pharmaceutical composition for preventing or treating cancer or bone disease and a food composition for alleviating canc...  
WO/2019/009956A1
Provided herein are methods for preparing ketone-containing organic molecules. The methods are based on novel iron/copper-mediated ("Fe/Cu-mediated") coupling reactions. The Fe/Cu-mediated coupling reaction can be used in the preparation...  
WO/2019/009693A1
The present invention relates to the use of the compound Cur-[G-2]-OH as a sensitiser in a wide range of multiresistant tumors, particularly glioblastoma, which are characterised by the overexpression of the Nrf2 pathway.  
WO/2019/010414A1
This disclosure concerns fatty acid derivatives, pharmaceutical compositions comprising the fatty acid derivatives, and methods of using the fatty acid derivatives, for example, to treat inflammation, chronic itch, chronic pain, an autoi...  
WO/2019/006993A1
The present invention relates to a method for preparing perfluoroethyl isopropyl ketone, comprising: using perfluoro-4-methyl-2-amylene or a mixture of perfluoro-4-methyl-2-amylene and perfluoro-2-methyl-2-amylene as a raw material; firs...  
WO/2019/008002A1
The invention relates to a composition comprising a) a polymer and b) (i) a phenolic metal salt of formula (I) Mn+ (L-)n wherein n is 1, 2 or 3, Mn+ is a metal ion and L- is an anion of formula (II) wherein A1 and A2 are both -CH2-CH2-, ...  
WO/2019/006143A1
The present invention relates to process and apparatus for removing aldehydes from acetone. More specifically, the present invention relates to a process and apparatus for removing aldehydes from acetone by reacting the aldehydes with ca...  
WO/2019/005273A1
Disclosed are a process for abating 3-cyclohexenone from a feed mixture comprising 3-cylclohexenone and cyclohexanone, comprising a hydrogenation step of contacting the feed mixture with hydrogen in the presence of a hydrogenation cataly...  

Matches 1 - 50 out of 19,116