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Matches 1 - 50 out of 1,084

Document Document Title
WO/2014/059158
The invention provides a compound of formula (I): [insert formula (I)] wherein X, Y, and R1-R4 have any of the values defined in the specification, and salts thereof, as well as compositions comprising the compounds or salts. The compoun...  
WO/2014/011753
Rhein analogues that exhibit anti-proliferative activity, particular against cancer cells, are described herein. In some embodiments, the compounds contain a flat or planar ring system. Such rings system by facilitate non-covalent bindin...  
WO/2014/012009
The present invention in one embodiment provides a compound of Formula I:(I), or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula I are as defined in the specification.  
WO/2014/011753
Rhein analogues that exhibit anti-proliferative activity, particular against cancer cells, are described herein. In some embodiments, the compounds contain a flat or planar ring system. Such rings system by facilitate non-covalent bindin...  
WO/2013/159593
The present invention relates to the biological field, and provides a method for extracting coenzyme Q10 and an application of the coenzyme Q10. The extracting method comprises: A. drying palm residues; B. extracting the dried palm resid...  
WO/2013/121190
The present invention discloses a simple method for transforming cashew nut shell liquid into an active herbicidal composition.  
WO/2013/121873
This production method for a biaryl compound includes a step in which phenol or naphthol is reacted in the presence of tetrabutylammonium iodide and either tert-butyl hydroperoxide or hydrogen peroxide.  
WO/2013/093937
The present invention relates to atovaquone prodrug compound of formula (I). Accordingly, present invention provides a process involving condensation of Atovaquone (II) with 5-methyl-4- chloromethyl dioxalone (III) in suitable solvent sy...  
WO/2013/093937
The present invention relates to atovaquone prodrug compound of formula (I). Accordingly, present invention provides a process involving condensation of Atovaquone (II) with 5-methyl-4- chloromethyl dioxalone (III) in suitable solvent sy...  
WO/2013/067547
The present invention discloses utilization of the anthracene-9,10-dione dioxime compound: 2-((3R,5S)-3,5-dimethylpiperdin-1ylsulfonyl)-7-((3S,5R)-3,5- dimethylpiperidin-1-ylsulfonyl)anthracene-9,10-dione dioxime for the treatment of can...  
WO/2013/041676
The present invention relates to a process of preparing tocotrienol quinones. It has been found that this process allows the formation of the R-isomer in a high yield in a very efficient and economically interesting way. Said process is ...  
WO/2012/162589
The invention described herein pertains to compounds and compositions for treating Ape1 mediated diseases. In particular, the invention described herein pertains to quinone compounds and pharmaceutical compositions containing them for tr...  
WO/2012/153162
Provided is a process of preparation of 2-[trans,-4-(4'-chlorophenyl)cyclohexyl]-3-hydroxy- 1,4-naphthoquinone, i.e. Atovaquone [I] which is cost effective, green, and eco-friendly process, without separation of any diastereomers or geom...  
WO/2012/138765
The invention provides methods and compositions for treatment of a subject with a central nervous system (CNS) tumor comprising administration of Coenzyme Q10 (CoQ10), particularly when the subject exhibits at least one CNS abnormality a...  
WO/2012/080243
Disclosed herein is novel process for preparation of atovaquone, which process includes reacting1H-2-benzopyran-1,4(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in t...  
WO/2012/073041
The invention provides a compound with the structural formula of any one of Formula 1 to Formula 18 or a pharmaceutically acceptable salt thereof, and uses thereof.  
WO/2012/055253
A regeneration method of chromatographic silica gel, especially a regeneration method of silica gel for chromatographing coenzyme Q10 is provided, wherein a high polar solvent is fed from the bottom of the chromatographic column to wash ...  
WO/2012/053408
The anti-Leishmania compound represented by formula (1).  
WO/2012/041918
The present invention relates to a process for the preparation of aqueous hydrogen peroxide from the anthraquinone (AO) loop process, comprising using at least one alkylanthraquinone of formula (I) wherein -R1, R2 and R3 are chosen from ...  
WO/2012/041918
The present invention relates to a process for the preparation of aqueous hydrogen peroxide from the anthraquinone (AO) loop process, comprising using at least one alkylanthraquinone of formula (I) wherein -R1, R2 and R3 are chosen from ...  
WO/2012/028905
The present invention describes a process for producing 2-methyl-l,4-naphthoquinone by oxidizing 2-methylnaphthalene with fresh hydrogen peroxide in the presence of glacial acetic acid without any mineral or transition metal catalyst.  
WO/2012/022468
The present invention relates to benzoquinone derivatives which are efficient as modulators of mitochondrial function and as such are useful for the treatment of pathological conditions where mitochondrial function is impaired.  
WO/2012/022467
The present invention relates to novel benzoquinone derivatives. The compounds are efficient as modulators of mitochondrial function and as such are useful for the treatment of pathological conditions where mitochondrial function is impa...  
WO/2012/022468
The present invention relates to benzoquinone derivatives which are efficient as modulators of mitochondrial function and as such are useful for the treatment of pathological conditions where mitochondrial function is impaired.  
WO/2012/022467
The present invention relates to novel benzoquinone derivatives. The compounds are efficient as modulators of mitochondrial function and as such are useful for the treatment of pathological conditions where mitochondrial function is impa...  
WO/2012/019029
Methods of treating, preventing or suppressing symptoms associated with mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), dominant optic atrophy (DOA); mitochondrial myopathy, encepha...  
WO/2012/019032
Methods of treating, preventing or suppressing symptoms associated with mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), dominant optic atrophy (DOA); mitochondrial myopathy, encepha...  
WO/2012/006321
The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention al...  
WO/2012/004875
[Problem] To provide an antioxidant which has an effective antioxidant effect without showing any side effects. [Solution] A novel substance represented by formula (1).  
WO/2011/141595
The invention relates to a method for the catalytic oxidation of anthracenes to anthraquinones, including a catalytic system based on copper compounds of formula TpxCu(NCMe), that promotes the selective oxidation of anthracene and 2-ethy...  
WO/2011/117324
A new process for making polyprenols is described as well as the use of these building blocks in the synthesis of Vitamin K2. The process involves reaction of a compound of formula (X) with a compound of formula (XI) in the presence of a...  
WO/2011/117429
Cannabinoid quinone derivatives.The present invention refers to cannabinoid quinone derivatives to be used as medicaments, particularly as PPAR gamma (PPARg) agonists for treating diseases which etiology is based on an impaired PPARg fun...  
WO/2011/113284
Shikonin naphthazarin derivatives represented by formula I and their preparation method are disclosed, wherein Ri~R4 and R are defined as in the description. The antitumor use of the compounds is also disclosed.  
WO/2011/071130
The present invention provides a novel alizarin derivative compound and a simplified and low cost method for preparing an alizarin derivative compound including: obtaining a compound represented by Formula (2) using a compound represente...  
WO/2011/066392
The present invention is directed towards a new class of semi-conducting acene derivatives. These compounds are all soluble species and they all possess superior resistance to photooxidation as compared to their counterparts that lack th...  
WO/2011/059355
This invention relates to the fields of pharmaceutics and medicine, and, in particular, concerns the production and use of pharmaceutical substances on the basis of mitochondrially addressed compounds. The invention discloses methods for...  
WO/2011/055142
The invention provides 1,4-quinones, 1,4-naphthoquinones and their sulphur analogues as inhibitors of hNAT1, an enzyme which is both a diagnostic marker and drug target for breast cancer. Some of the compounds of the invention are also c...  
WO/2011/055142
The invention provides 1,4-quinones, 1,4-naphthoquinones and their sulphur analogues as inhibitors of hNAT1, an enzyme which is both a diagnostic marker and drug target for breast cancer. Some of the compounds of the invention are also c...  
WO/2011/034922
The present invention provides a method for making hypericin comprising the steps of converting a protohypericin to a protohypericin salt, and irradiating the protohypericin salt with visible light to form hypericin. The present inventio...  
WO/2011/021230
Disclosed are complexes of an antipneumocystic compound and an antimalarial compound, processes for their preparation, pharmaceutical compositions and methods of using said complexes or compositions for the treatment and/or prophylaxis o...  
WO/2011/022286
The application relates to quinhydrone (RN=106-34-3) containing sensors (10) for e.g. potentiometric measurements, especially in vivo measurements such as potentiometric pH measurements in wounds. In particular, the application describes...  
WO/2011/017519
The invention is directed towards novel naphthoquinone and naphthothiazole compounds, and methods of treating disorders related to MetAP, including tuberculosis and bacterial infection, using various naphthoquinone, hydroxyquinonline, an...  
WO/2011/017519
The invention is directed towards novel naphthoquinone and naphthothiazole compounds, and methods of treating disorders related to MetAP, including tuberculosis and bacterial infection, using various naphthoquinone, hydroxyquinonline, an...  
WO/2010/135759
The invention relates to two novel substances, specifically (1R,2S,3S,4R)-3-acetoxy-1,2,4,5-tetrahydroxy-y-methoxy-2-met hyl-1,2,3,4-tetrahydroanthracene-9,10-dione (3-O-acetyl-altersolanol M) (I) and 8-(4,5,6-trihydroxy-7-methyl-2-metho...  
WO/2010/121638
The present invention discloses a process for the recovery of Menadione from spent mother liquor containing a Menadione Bisulfite derivative, whereby the pH of the mother liquor is increased.  
WO/2010/118660
Disclosed is a method for synthesizing substituted anthraquinone with high purity. The substituted anthraquinone is obtained by the following step: the product which is obtained by reacting 3-X1 substituted benzoic acid anhydride with X2...  
WO/2010/113900
Disclosed is a production method for ubiquinone powder for use in preparations that involves a process (1) for obtaining compressed fragments by compression molding ubiquinone crystal powder at a linear molding pressure of 0.6-2.5 ton/cm...  
WO/2010/071941
The invention relates to plant extracts and bioactive molecules derived from the plant genus Acronychia and their use as antioxidants, antibacterials, anthelmintic, anti-inflammatories, cancer chemopreventatives, food additives and fragr...  
WO/2010/059880
Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photo-induced damage mitigating agents to the reacti...  
WO/2010/059880
Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photo-induced damage mitigating agents to the reacti...  

Matches 1 - 50 out of 1,084