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JPH06206846A |
PURPOSE: To provide the new physiologically active substances, bequinostatins C and D, and their pharmacologically acceptable salts strongly inhibiting glutathione transferase, and extremely useful as a glutathione transferase inhibitor....
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JPH0653701B2 |
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JPH0653702B2 |
PURPOSE:To separate and purify vitamin K2 isomers, by adding an organic solvent, e.g. lower alcohol, soluble in the vitamin K2 isomers thereto and using supercritical fluid chromatography. CONSTITUTION:Vitamin K2 isomers are industrially...
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JPH06192155A |
PURPOSE: To obtain a new compound exhibiting an interleukin-1 inhibitory activity and useful as an interleukin-1 inhibitor. CONSTITUTION: A compound of formula I (R1 is a lower alkyl), formula II (R2 is hydroxymethyl or carboxyl), formul...
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JPH0647564B2 |
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JPH0645567B2 |
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JPH0645568B2 |
PURPOSE:To obtain a physiologically active substance having an inihibitory activity against protocollagen-proline hydroxylase, by cultivating a specific microorganism belonging to the genus Streptomyces. CONSTITUTION:Streptomyces sp. No....
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JPH0643584B2 |
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JPH06157395A |
PURPOSE: To industrially and advantageously obtain a compound useful as an intermediate for dye for fiber, pigment, agricultural chemical, medicine and optical material by chlorinating p-aminophenol with a chlorine gas in a specific alco...
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JPH0639468B2 |
There is described a novel process for the manufacture of hydroquinone derivatives of the formula II wherein R represents an ether protecting group, and their conversion into d- alpha -tocopherol starting from compounds of the formula I ...
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JPH0637414B2 |
Vitamin K3 (I; 2-methylnaphtho-1,4-quinone), vitamin K4 (IIa; 2-methyl-1,4-dihydroxynaphthalene) and vitamin K4 diacetate (IIb) are prepared by reacting 1-acetoxy-buta-1,3-diene (IV) with methylbenzoquinone (V) to give the novel compound...
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JPH0637379B2 |
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JPH0637388B2 |
This invention relates to an aqueous preparation comprising a compound (A) represented by the formula:and at least one of cyclodextrins selected from a a-cyclodextrin and dimethyl-β-cyclodextrin; and a method of preparation thereof.Acco...
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JPH0635548B2 |
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JPH0635417B2 |
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JPH06128187A |
PURPOSE: To obtain a new compound, having antitumor activity and useful as an antitumor agent. CONSTITUTION: A compound of formula I [A is formula II or III (R1 and R2 are H or alkyl); X is OH, halogen, etc.], e.g. 2-(2,6-dimethyl-8-(tet...
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JPH0629212B2 |
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JPH0627092B2 |
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JPH06100569A |
PURPOSE: To provide a novel compound having a DNA-cleaving action and an active oxygen species-eliminating action and useful for autoimmune disease- therapeutic agents, antiarteriosclerosis agents. carcinogenesis-preventing agents, infla...
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JPH0625095B2 |
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JPH0623123B2 |
A bicyclic compound of the following formula : wherein A is @C=O or @CHOH, R<1> is aryl which may have cyano or carbamoyl, or heterocyclic group which may have lower alkyl, R<2> is hydrogen or lower alkyl, R<3> is lower alkyl, X is hydro...
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JPH0687737A |
PURPOSE: To obtain an anti-AIDS agent having activity capable of suppressing proliferation of HIV in infected cell. CONSTITUTION: The anti-AIDS agent contains 1-methoxy-2-formyl-3- hydroxyanthraquinone expressed by the formula as an acti...
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JPH0621099B2 |
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JPH0621098B2 |
The present invention relates to novel calixarene derivatives having an inclusion activity which are useful for selective transportation of various metal ions, possess a biological activity and a redox activity, and are not only capable ...
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JPH0621089B2 |
The invention relates to a novel process for the preparation of ether and thioether compounds of formula by reacting compounds of formula with compounds of formula R1-Y wherein R, R1, X, Y and n are as defined in claim 1, in the presence...
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JPH0680658A |
PURPOSE: To efficiently obtain the compound in high yield which is useful as an intermediate or the like of a pharmaceutical or the like by nucleophilically substituting and cyclizing a particular quinone obtained from a trialkylhydroqui...
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JPH0680607A |
PURPOSE: To obtain a new malbranicin, having antibacterial and carcinostatic actions and useful as a medicine. CONSTITUTION: The objective malbranicin is expressed by the formula. This compound is obtained by culturing a strain having th...
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JPH0672940A |
PURPOSE: To provide a new compound having excellent light-resistance and fastness and especially useful as a dye and recording pigment. CONSTITUTION: The compound of formula I [R1 is H, 1-3C alkyl or NHR2 (R2 is 1-3C alkyl, phenyl, etc.)...
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JPH0617329B2 |
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JPH0649372A |
PURPOSE: To obtain a reactive water-soluble triphenodioxazine dye usable to prepare a high concn. liq. dye formulation having the respective specified atom and group in a plurality of prescribed positions and superior dyeing characterist...
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JPH0622774A |
PURPOSE: To produce a useful physiologically active substance unobtainable by respective individual culture of a cultured plant cell and a photosynthetic autotrophic microorganism, e.g. a new benzoquinone-based substance useful as a food...
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JPH0625063A |
PURPOSE: To provide a new compound having excellent antitumor activity. CONSTITUTION: The compound of formula I [X is halogen; R1 is H or alkyl; R2 is hydroxy or halogen; R3 is hydroxy, alkoxy, aralkyloxy or NR4R5 (R4 and R5 are H, alkyl...
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JPH066549B2 |
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JPH061746A |
PURPOSE: To provide a new intermediate compound capable of stereoselectively synthesizing a high-purity dioxophenanthrene derivative useful as an IL-1 inhibitor in large quantity. CONSTITUTION: The compound of formula I (R1 to R3 are low...
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JPH06716B2 |
1. Compounds of the formula see diagramm : EP0169571,P20,F2 wherein R1 signifies hydrogen, lower alkyl, chlorine, fluorine or trifluoromethyl ; R2 signifies hydrogen, lower alkoxy, trifluoromethyl-lower alkoxy, hydroxy, lower alkyl, chlo...
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JPH0581579B2 |
Quinone derivatives represented by general formula (I) wherein R<1> and R<2> may be the same or different, and each represents hydrogen, methyl or methoxy or, when taken together, R<1> and R<2> represent -CH=CH-CH=CH-, R<3> represents hy...
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JPH0579055B2 |
An improved process for producing 2-methyl-1,4-naphthoquinone with a high yield comprising reaction of a 1-lower-alkoxy-2-methyl naphthalene with hydrogen peroxide in the presence of a hexacyanoferric acid or a salt thereof as catalyst. ...
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JPH0579054B2 |
There is provided a process of producing p-benzoquinone, wherein hydroquinone and hydrogen peroxide are reacted in water, an aqueous inorganic acid solution, an inert organic polar solvent or a mixture of water with an inert organic pola...
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JPH0578537B2 |
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JPH0578538B2 |
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JPH0577455B2 |
A condensation reaction catalyst useful for producing an organic compound, for example, anthraquinone compounds from phthalic anhydride and optionally benzene, comprises a catalytic principal component consisting of a solid acid substanc...
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JPH05271145A |
PURPOSE: To obtain new physiological active substance bequionstain A and B having high specificity, inhibitory activity against glutathione transferase and immunomodulating action and its pharmaceutically acceptable salt. CONSTITUTION: A...
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JPH05259493A |
PURPOSE:To provide an organic photovoltaic device (organic solar cell) which allows a larger area and a higher conversion rate. CONSTITUTION:Relating to an organic photovoltaic device in which laminated layers of an electron acceptive or...
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JPH05246933A |
PURPOSE: To obtain a new fluoroalkyl group-containing anthraquinone compound usable as a compound having high light resistance and fastness, especially as dye and a coloring matter for recording. CONSTITUTION: A compound of formula I [R1...
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JPH05238982A |
PURPOSE: To obtain a new antitumor agent showing higher medicinal effects on cancerous cells, comprising a specific compound as a metabolite of a bacterium belonging to the genus Streptomyces. CONSTITUTION: An antitumor agent comprising ...
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JPH05238981A |
PURPOSE: To obtain the subject new compound having ultraviolet rays absorbing action, mixable as an ultraviolet rays absorber of natural source with cosmetic, etc. CONSTITUTION: An anthraquinone-based compound expressed by formula. Appea...
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JPH0565496B2 |
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JPH0563881B2 |
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JPH05221915A |
PURPOSE: To obtain a new benzoquinone derivative useful as an antioxidant and an anti-inflammatory agent. CONSTITUTION: A 1,4-benzoquinone derivative of formula I [R1 is (CH2)m= CH(CH2)nCH3 (m is integer of 2-15; n is integer of 1-5; eit...
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JPH05194784A |
PURPOSE: To photo-cure a composition obtained by photopolymerizing photopolymerizable organic materials such as epoxy resins to a greater depth and thickness. CONSTITUTION: Photopolymerizable organic resin compositions are comprised of (...
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