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Matches 51 - 100 out of 2,259

Document Document Title
WO/2011/113284A1
Shikonin naphthazarin derivatives represented by formula I and their preparation method are disclosed, wherein Ri~R4 and R are defined as in the description. The antitumor use of the compounds is also disclosed.  
WO/2011/071130A1
The present invention provides a novel alizarin derivative compound and a simplified and low cost method for preparing an alizarin derivative compound including: obtaining a compound represented by Formula (2) using a compound represente...  
WO/2011/066392A1
The present invention is directed towards a new class of semi-conducting acene derivatives. These compounds are all soluble species and they all possess superior resistance to photooxidation as compared to their counterparts that lack th...  
WO/2011/059355A1
This invention relates to the fields of pharmaceutics and medicine, and, in particular, concerns the production and use of pharmaceutical substances on the basis of mitochondrially addressed compounds. The invention discloses methods for...  
WO/2011/055142A2
The invention provides 1,4-quinones, 1,4-naphthoquinones and their sulphur analogues as inhibitors of hNAT1, an enzyme which is both a diagnostic marker and drug target for breast cancer. Some of the compounds of the invention are also c...  
WO/2011/055142A3
The invention provides 1,4-quinones, 1,4-naphthoquinones and their sulphur analogues as inhibitors of hNAT1, an enzyme which is both a diagnostic marker and drug target for breast cancer. Some of the compounds of the invention are also c...  
WO/2011/034922A1
The present invention provides a method for making hypericin comprising the steps of converting a protohypericin to a protohypericin salt, and irradiating the protohypericin salt with visible light to form hypericin. The present inventio...  
WO/2011/022286A1
The application relates to quinhydrone (RN=106-34-3) containing sensors (10) for e.g. potentiometric measurements, especially in vivo measurements such as potentiometric pH measurements in wounds. In particular, the application describes...  
WO/2011/021230A3
Disclosed are complexes of an antipneumocystic compound and an antimalarial compound, processes for their preparation, pharmaceutical compositions and methods of using said complexes or compositions for the treatment and/or prophylaxis o...  
WO/2011/017519A3
The invention is directed towards novel naphthoquinone and naphthothiazole compounds, and methods of treating disorders related to MetAP, including tuberculosis and bacterial infection, using various naphthoquinone, hydroxyquinonline, an...  
WO/2011/017519A2
The invention is directed towards novel naphthoquinone and naphthothiazole compounds, and methods of treating disorders related to MetAP, including tuberculosis and bacterial infection, using various naphthoquinone, hydroxyquinonline, an...  
WO/2010/135759A1
The invention relates to two novel substances, specifically (1R,2S,3S,4R)-3-acetoxy-1,2,4,5-tetrahydroxy-y-methoxy-2-met hyl-1,2,3,4-tetrahydroanthracene-9,10-dione (3-O-acetyl-altersolanol M) (I) and 8-(4,5,6-trihydroxy-7-methyl-2-metho...  
WO/2010/121638A1
The present invention discloses a process for the recovery of Menadione from spent mother liquor containing a Menadione Bisulfite derivative, whereby the pH of the mother liquor is increased.  
WO/2010/118660A1
Disclosed is a method for synthesizing substituted anthraquinone with high purity. The substituted anthraquinone is obtained by the following step: the product which is obtained by reacting 3-X1 substituted benzoic acid anhydride with X2...  
WO/2010/113900A1
Disclosed is a production method for ubiquinone powder for use in preparations that involves a process (1) for obtaining compressed fragments by compression molding ubiquinone crystal powder at a linear molding pressure of 0.6-2.5 ton/cm...  
WO/2010/071941A1
The invention relates to plant extracts and bioactive molecules derived from the plant genus Acronychia and their use as antioxidants, antibacterials, anthelmintic, anti-inflammatories, cancer chemopreventatives, food additives and fragr...  
WO/2010/059880A2
Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photo-induced damage mitigating agents to the reacti...  
WO/2010/059880A3
Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photo-induced damage mitigating agents to the reacti...  
WO/2010/054452A1
The invention belongs to the chemical pharmaceutical field, and the new compounds of the pterocarpanquinone family having formula (I) according to the invention can be reduction activated, generating alkylating species in the intracellul...  
WO/2010/034999A1
A compound of formula (I) in solid form, preferably crystalline form.  
WO/2010/035000A8
Using a combination of Kumada, Suzuki and Biellmann chemistry, various menaquinones can synthesised rapidly and with stereochemical integrity offering a new way of preparing these vitamin K2 components for the pharmaceutical market. In o...  
WO/2010/035000A1
Using a combination of Kumada, Suzuki and Biellmann chemistry, various menaquinones can synthesised rapidly and with stereochemical integrity offering a new way of preparing these vitamin K2 components for the pharmaceutical market. In o...  
WO/2010/023686A2
Disclosed herein discloses a crystalline form of 2-Chloro-3-[4-(4-chlorophenyl) cyclohexyl] [l,4]naphthoquinone and process for preparing the same and use thereof. The present invention also provides a process for producing 2-[4-(4- chlo...  
WO/2010/023686A3
Disclosed herein discloses a crystalline form of 2-Chloro-3-[4-(4-chlorophenyl) cyclohexyl] [l,4]naphthoquinone and process for preparing the same and use thereof. The present invention also provides a process for producing 2-[4-(4- chlo...  
WO/2010/009492A1
Atovaquone or a pharmaceutically acceptable salt thereof having a particle size diameter range with a D90 of between greater than 3 to about 10µm.  
WO/2010/002994A1
Novel compounds and compositions for treating patients in need of relief from HIV, AIDS, and AIDS-related diseases are described. Methods for treating HIV, AIDS, and AIDS-related diseases using the compounds described herein are also des...  
WO/2010/001378A1
Provided is a process for the epimerization of the cis isomer of atovaquone, atovaquone intermediates and isomeric mixtures thereof into their corresponding trans-isomers resulting in higher yield of pure atovaquone.  
WO/2010/001379A1
The invention provides novel intermediates of atovaquone and use thereof for the preparation of atovaquone  
WO/2009/158348A1
Methods of treating or suppressing oxidative stress disorders including mitochondrial diseases, impaired energy processing disorders, neurodegenerative diseases and diseases of aging are disclosed, as well as compounds useful in the meth...  
WO/2009/141562A3
The invention relates to quinones of formula (Ia) or (Ib), in which Formula (Ia) and Formula (Ib) R1 and R2 each independently represent - a hydrogen atom, - a C1-3O alkyl group in which one or more -CH2- linkages, apart from the attachm...  
WO/2009/141562A2
The invention relates to quinones of formula (Ia) or (Ib), in which Formula (Ia) and Formula (Ib) R1 and R2 each independently represent - a hydrogen atom, - a C1-3O alkyl group in which one or more -CH2- linkages, apart from the attachm...  
WO/2009/118327A1
Derivatives of formula (I) wherein A is selected from the following rings: and their preparation and their application as antimalarial agents.  
WO/2009/118443A1
The invention relates to oviedomycin derivatives, the method for obtaining same and the use thereof. The invention relates to oviedomycin derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates t...  
WO/2009/098082A3
The present invention relates to naphthoquinone derivatives isolated from solid callus cultures from two species of the palaeotropical plant families Dioncophyllaceae and Ancistrocladaceae. It further relates to methods of their producti...  
WO/2009/098082A2
The present invention relates to naphthoquinone derivatives isolated from solid callus cultures from two species of the palaeotropical plant families Dioncophyllaceae and Ancistrocladaceae. It further relates to methods of their producti...  
WO/2009/068322A1
The present invention relates to compounds having a 1,4-benzoquinone or 1,4- benzoquinone imine scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds tog...  
WO/2009/063485A3
The present invention is related to the therapeutic uses of vitamin K, its analogues and derivatives in a diverse array of disease conditions. Vitamin K improves blood perfusion and ameliorates hypoxia in prevention and treatment of cond...  
WO/2009/016083A1
Disclosed are a method for improving the degradation of natural and/or synthetic polymers or a polymer article made from such polymer(s) by light and/or heat and/or humidity, comprising the incorporation of a compound of formula (I) into...  
WO/2009/007991A3
Disclosed herein is novel process for preparation of Atovaquone, which process includes reacting 1,4-naphthoquinone with trans-4-(4-chlorophenyl) cyclohexane carboxylic acid followed by halogenation to obtain dihalo-compound, further deh...  
WO/2009/007991A2
Disclosed herein is novel process for preparation of Atovaquone, which process includes reacting 1,4-naphthoquinone with trans-4-(4-chlorophenyl) cyclohexane carboxylic acid followed by halogenation to obtain dihalo-compound, further deh...  
WO/2009/004900A1
Disclosed are: an immunoadjuvant which has an excellent function of enhancing the production of an antibody and is highly safe; and a vaccine composition comprising the immunoadjuvant. More specifically disclosed are: an immunoadjuvant c...  
WO/2009/001367A3
The present invention relates to two novel and stable crystalline forms of atovaquone, to the processes for their preparation and to pharmaceutical compositions comprising them. The present invention also provides crystalline particles o...  
WO/2009/001367A2
The present invention relates to two novel and stable crystalline forms of atovaquone, to the processes for their preparation and to pharmaceutical compositions comprising them. The present invention also provides crystalline particles o...  
WO/2008/139290A1
The invention concerns a new process for the preparation of naphthoquinones, in particular an improved process for the preparation of 2,3-disubstituted 1,4- naphthoquinones, in the trans configuration.  
WO/2008/122988A1
Substantially pure atovaquone and parocess for the preparation thereof is disclosed.  
WO/2008/111515A1
Disclosed is a simple and highly efficient process for producing an aromatic carbonyl compound, which can produce an aromatic carbonyl compound having a substituent introduced to an aromatic ring adjacent to a carbonyl group. The process...  
WO/2008/107878A1
Novel cannabinoid-derived quinone derivatives (quinonoid derivatives) having a substituted hydroxyl group, pharmaceutical compositions comprising same and uses thereof as anti-proliferative agents, are provided.  
WO/2008/108105A1
A specific quinone compound, which contains two quinone groups at ortho positions and has such a characteristic that an electron transfer is caused during a reversible oxidation-reduction reaction, is oligomerized or polymerized. Consequ...  
WO/2007/129269A3
The present invention relates to an improved process for the preparation of Coenzyme Q. Coenzyme QlO or CoQlO has the chemical name 2- [(all -trans)- 3, 7,l l,15,19,23,27,31,35,39-decamethyl-2, 6, 10, 14, 18, 22, 26, 30, 34, 38 - tetraco...  
WO/2007/125919A1
Disclosed is a sulfonated polymer having excellent workability and excellent methanol resistance. More specifically, disclosed is an aromatic compound represented by the general formula (1): (1) wherein A, D and E independently represent...  

Matches 51 - 100 out of 2,259