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JP56075450 |
PURPOSE: To prepare the titled compound easily, in high yield, in a short time, by dissolving 3,4,5-trimethoxytoluene in water-lower alcohol mixture containing a strong acid, adding an aqueous solution of a persulfate to the solution, an...
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JP56075449 |
PURPOSE: To prepare a slurry of anthraquinone fine crystals in sulfuric acid, by dissolving anthraquinone in concentrated sulfuric acid with heating, and adjusting the concentration of sulfuric acid first by adding sulfuric acid of speci...
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JP56061371 |
PURPOSE: To obtain the titled substance which is an intermediate for a substituted benzoquinone, e.g. vitamin K, coenzyme Q, etc., by coupling a 2,3-substituted-5- methyl-1,4-hydroquinone derivative with a halide, and introducing a subst...
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JP56051986 |
PURPOSE: To prepare coenzyme Q10, by cultivating a microorganism belonging to the genus Pseudomonas. CONSTITUTION: A new strain belonging to the genus Pseudomonas, e.g. Pseudomonas C1-36 (FERM-P No. 5209) is inoculated into a nutrient me...
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JP56040635 |
PURPOSE: To obtain the titled compound useful as a remedy for congestive heart, etc. in high efficiency, from a saponification product of concentrated Q10 accumulated in the distillation residue obtained by the decomposition and distilla...
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JP56039037 |
PURPOSE: To prepare 1,4-naphthoquinone, economically, in an industrial scale, by the oxidation of naphthalene with molecular oxygen in the presence of a catalyst consisting of particles having holes penetrating therethrough to increase t...
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JP56032433 |
PURPOSE: After 3-nitrophthalic anhydride is subjected to chlorination, benzoylation and decomposition with dilute hydrochloric acid, the reaction mixture is only stirred in benzene under reflux to facilitate the filtration of the slurry,...
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JP56032434 |
PURPOSE: After 3-nitrophthalic anhydride is subjected to chlorination, benzoylation and dehydrative ring closure with concentrated sulfuric acid, the reaction mixture is diluted with water until the concentration of sulfuric acid reaches...
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JP56030941 |
PURPOSE: To purify a coenzyme Q useful as a remedy for heart failure etc., economically, in an industrial scale, by subjecting crude coenzyme Q to an adsorption process, an elution process and an adsorbent-cleaning process using silica g...
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JP56025130 |
PURPOSE: To purify a high melting point compound, continuously and economically, by extracting the bottom product containing nonvolatile impurities produced in the rectifying column, easily, continuously, stably, without affecting the pr...
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JP56012335 |
PURPOSE: To obtain the titled compound safely, readily and in high yield, by the reaction of 9,10-phenanthrene oxide with chlorine, in a water-organic solvent, in the first reaction stage adjusted to a lower pH and in the second stage ad...
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JP56007734 |
PURPOSE: To obtain the title compound having a pharmacological activity, in high yield and purity, by the oxidation of a compound, e.g. 6-(10'-hydroxydecyl)-2,3- dimethoxy-5-methylphenol, with O2 or air, in the presence of a transition m...
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JP56007737 |
NEW MATERIAL:A quinone of formula I [α-β part is saturated or double bond; R is methyl or methoxy, or two Rs are bonded into CH=CH-CH=CH; R1 is carboxyl, aldehyde, (CH2)mOH, etc.; m is an integer 1W3; R2 is H or hydroxyl group; n is an...
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JP55164643 |
PURPOSE: To obtain a high purity coenzyme Q, which takes an important role in the biological electron transport system and has an excellent pharmaceutical activity for various diseases, at room temp., easily, in the yield, by recrystalli...
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JP55159797 |
PURPOSE: To purify the title coenzyme Q efficiently, by adsorbing a crude coenzyme Q on a carbonaceous synthetic resin, and by eluting the coenzyme Q with a polar or nonpolar solvent or both. CONSTITUTION: A crude coenzyme Q prepared by ...
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JP55157535 |
PURPOSE: To obtain 2,3-di(lower alkoxy)-5-methyl-1,4-benzoquinone in high yield, by adding an aqueous persulfuric acid salt to a suspension of 3,4,5-tri(lower alkoxy) toluene in a solvent, e.g. water, at a specific temp. CONSTITUTION: An...
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JP55143928 |
PURPOSE: To obtain the title compound, useful as a coenzyme Q in simple procedures, by condensing a hydroquinone derivative with a prenol in the presence of a catalyst in a specific mixed solvent, and by oxidizing the hydrocarbon solvent...
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JP55143927 |
PURPOSE: To separate the title compounds, useful as intermediates for dyes and pigments in high purity, by extracting an aqueous slurry catalytic oxidation product of naphthalene with a specific saturated hydrocarbon at a specific pH and...
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JP55118437 |
PURPOSE: To obtain a coenzyme Q in high yield with supressed side reactions, by condensing 2,3-dimethoxy-5-methyl-p-benzohydroquinone and prenylalcohol in the presence of Lewis acid after adding an amide or urea to the reaction system, a...
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JP55118436 |
PURPOSE: To obtain 2-t-alkyl-substituted anthraquinone in high yield, by the vapor phase oxidation of a diphenylmethane-type compound, using a catalyst comprising V and Ce and having a high and long activity. CONSTITUTION: A diphenylmeth...
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JP55115845 |
PURPOSE: To obtain the title compound, co-enzyme Q10, etc. useful as a drug for heart diseases, by oxidizing a condensate, prepared from a hydroquinone derivative and (iso)prenyl alcohol in the presence of a nitroalkane and a Lewis acid ...
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JP55111439 |
PURPOSE: To prevent the scaling in a collector and the excessive growth of crystal in a slurry, in the washing and collection of naphthoquinone and phthalic anhydride from the gas produced by the vapor-phase catalytic oxidation reaction ...
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JP55104225 |
NEW MATERIAL:Anthracyclines of formula I (the configuration in the 7-position is S or R; X is H or formula II). EXAMPLE: 10-Decarbomethoxyaclacinomycin A. USE: They have antitumorigenic activity and effectively prohibit the propagation o...
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JP55102535 |
PURPOSE: To prepare highly pure 1,5- and 1,8-diphenoxyanthraquinones useful as intermediates for production of dyes, separately, in high yield, by separating the mixture of 1,5- and 1,8-diphenoxyanthraquinones into the individual constit...
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JP55092691 |
PURPOSE: To purify long-chain dicarboxylic acids produced by fermentation, economically and safely, by treating with a lower aliphatic alcohol, tetrahydrofuran, or their aqueous solution. CONSTITUTION: Long-chain dicarboxylic acids, esp....
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JP55087740 |
PURPOSE: To prepare a benzoquinone derivative useful as a medicine, e.g. a remedy for heart failure, vitamin K1, vitamin K2, etc., easily, in high yield without using a fatally poisonous substance, by reacting a paraquinone derivative wi...
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JP55072137 |
PURPOSE: To obtain the title compound useful as an assistant for production of H2O2, in a high extraction efficiency, by improving the separatory nature of aqueous and oily phases, in the presence of a specific compound, in extracting th...
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JP55072136 |
PURPOSE: To obtain the title compound useful as a starting material for tocopherol, in high purity and yield, by separating the reaction mixture produced through the oxidation of 2,3,6-trimethylphenol with O2 in a specific solvent. CONST...
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JP55069535 |
PURPOSE: To prepare the title compound useful as a raw material of coenzyme Q, easily, safely, and in high yield, by reacting a hydroquinone derivative with pulenol in the presence of an acidic condensation catalyst in a nitro compound a...
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JP55064543 |
PURPOSE: To facilitate the extraction of the title compound useful as an assistant for the production of hydrogen peroxide, and to prepare the title compound economically, by adding a specific aliphatic carboxylic acid to a reaction mixt...
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JP55064542 |
PURPOSE: To facilitate the extraction of the title compound useful as an assistant for the production of hydrofen peroxide, and to prepare the title compound economically, by adding a specific monohydric alcohol to a reaction mixture, th...
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JP55064544 |
PURPOSE: To prepare the title compound useful as an intermediate of coenzyme Q, economically, in high yield, in a short and simple procedure, by oxidizing 2-methyl- 4, 5, 6-trimethoxybenzaldehyde with a peroxide. CONSTITUTION: 2, 3-Dimet...
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JP55055132 |
PURPOSE: To prepare the title compound having excellent purity and color tone, and useful as a gelling agent and polymerization inhibitor of styrene, etc., by the dealkylation of an easily synthesizable 2,3-dialkoxy-1,4-naphtoquinone wit...
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JP55055133 |
PURPOSE: To obtain the title compound excellent in purity and color tone, useful as a gelling agent for styrene, and a polymerization inhibitor, by alkylation of an easily available 2,3-dialkoxy-1,4-naphthoquinone with an aqueous solutio...
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JP55047639 |
PURPOSE: To suppress the side reactions in the ring-closing reaction of an alkylbenzoyl benzoic acid in the presence of oleum, and to prepare the title compound useful as an additive for the preparation of H2O2, in high yield, by adding ...
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JP55045645 |
PURPOSE: To obtain a high purity coenzyme Q having excellent remedying effect to various diseases in the living body, easily in high recovery, by extracting crude coenzyme Q with a nitrile compound, adjusting the concentration of solute ...
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JP55045622 |
PURPOSE: To obtain the title compound useful as an assistant for the preparation of hydrogen peroxide, etc., in high yield, by the ring closure of alkylbenzoylbenzoic acid, using a specific ring-closing agent and selecting the reaction t...
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JP55040626 |
PURPOSE: To prepare the title compound, useful as an intermediate of medicines, and a photo-sensitive material, by reacting easily available p-benzoquinone or α- naphthoquinone with an alcohol in the presence of a cobalt-Schiff base com...
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JP55028960 |
NEW MATERIAL:Hydroquinone compounds of formula I [R1 is lower alkyl, methoxymethyl; R2,R3 are methyl, methoxy, or may be form benzene ring with directly connecting carbons; R4 is aromatic hydrocarbyl that may be substituted; n is 1W11]. ...
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JP55027114 |
PURPOSE: To obtain coenzyme Q useful esp. as a remedy for cardiac insufficiency, etc., easily and economically, by absorbing a reduction-type coenzyme Q to an absorbent such as silica gel, and the oxidizing the coenzyme Q. CONSTITUTION: ...
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JP55024143 |
PURPOSE: To prepare high purity naphthoquinone (NQ) useful as a raw material of anthraquinone, etc., without degradation, by contacting an NQ solution obtained by the gas phase catalytic oxidation of naphthalene, with an aqueous solution...
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JP55020752 |
NEW MATERIAL:Hydroquinone derivatives of formulaI (R1 is lower alkyl, R2, R3 are methyl, methoxy, or incorporate along with other carbon atoms to form benzene ring; R4 is aromatic hydrocarbyl). EXAMPLE: 2,3,5-Trimethyl-5-(3'-methyl-4'-be...
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JP55011520 |
PURPOSE: To separate the title substances, by mixing an aqueous slurry obtained through rinsing of a vapor-phase catalytic oxidation product gas of naphthalene with a water-immiscible solvent, and by adding a basic substance to the mixtu...
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JP54160327 |
PURPOSE: To obtain coenzyme Q, which is important pharmaceutically and takes part in electron transfer system in vivo in high yield, by the Grignard reaction of a halogenohydroquinone derinative with a prenyl derivative to form a hydroqu...
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JP54151932 |
PURPOSE: To obtain the title compound for treatment of muscular dystrophy, parodontitis, or congestive heart in high yield with high selectivity, by catalytic oxidation of a ubiquinol in the presence of silica gel and calcium sulfate as ...
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JP54151933 |
PURPOSE: To obtain the title compound usable for treatments of muscular dystrophy, prodontitis, or congestive heart in high yield, by reacting a ubiquinol with a combination of dimethyl sulfoxide and an electrophilic activating reagent. ...
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JP54144348 |
PURPOSE: To obtain the tittle compound useful as an intermediate for the synthesis of organic compounds industrially in high yield, by reacting a methylene compound with O2 in a solvent of a specific alkyl-2-imidazolidinone compound in t...
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JP54141755 |
PURPOSE: To obtain high-purity naphthoquinone, in high yield with ease and certainty, by oxidizing crude maphthoquinone (N) prepared through oxidation of naphthalene, and by distilling N with an acid content below a given value in vacuo....
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JP54129132 |
PURPOSE: Remedy and prophylactic for prostatomegaly, containing co-enzyme Q as an effective component. CONSTITUTION: The title medicine containing co-enzyme Q of formula (n is an integer of 7W10) as an effective component, and arbitrary ...
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JP54128558 |
PURPOSE: To purify a crude naphthoquinone obtained by the oxidation of naphthalene, in high yield and efficiency, without causing polycondensation of the naphthoquinone, by decreasing the acid content of the crude raw material below a sp...
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