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Matches 1 - 50 out of 2,428

Document Document Title
WO/2020/132178A1
Described are methods and compositions for inhibiting polymerization of a monomer (e.g., styrene) composition using a hydroxylated quinone antipolymerant. The hydroxylated quinone antipolymerant can be used with little or no nitroxyl gro...  
WO/2020/130080A1
The purpose of the present invention is to provide a method for synthesizing a p-quinone using one of alkoxy-substituted benzenes as a starting material. The present invention relates to a method for producing a compound of formula (II...  
WO/2020/123432A1
Provided are improved methods for Vitamin K, including but not necessarily limited to MK-7 production through bacterial fermentation using biofilm reactors. Fed-batch addition of carbon sources, such as glucose, are used as the base medi...  
WO/2020/105500A1
The objective of the present invention is to provide a processing method for a working solution, wherein the amount of anthraquinones is increased by regenerating, into anthraquinones, by-products derived from anthraquinones and having n...  
WO/2020/103118A1
A process for manufacturing a compound of formula (II), said process comprising a step of reacting a compound of formula (I) in the presence of a zeolite catalyst and a solvent, (I), (II) wherein R1, R2, R3, R4, R5, R6, R7 and R8 are ind...  
WO/2020/081601A1
The disclosure provides methods of treating pancreatic cancer in a population of subjects comprising administration of Coenzyme Q10. Administration of Coenzyme Q10 to the subjects increases the number of subjects in the population that e...  
WO/2020/067333A1
To provide a novel therapeutic agent for fibrosis that induces selective cell death of lung fibroblasts without injuring alveolar epithelial cells and thus inhibits lung fibrosis. A pharmaceutical composition for treating fibrosis that c...  
WO/2020/067275A1
Provided is a method for producing a reduced coenzyme Q10 Form II-type crystal with high efficiency. A method for producing a reduced coenzyme Q10 crystal, comprising warming a mixture of a reduced coenzyme Q10 Form I-type crystal and a ...  
WO/2020/068735A1
Described are methods and composition for inhibiting polymerization of a monomer (e.g., styrene) composition using an aminated quinone antipolymerant, such as an aminated benzoquinone or aminated naphthoquinone antipolymerant having one ...  
WO/2020/055678A1
The present application discloses methods for the efficient preparation of high purity compounds of the Formula I, and their methods of use.  
WO/2020/041871A1
This application is directed to the use of a ketogenic agent, such as 1,3-butanediol, R-β-hydroxybutyl-R-β-hydroxybutyrate, or triheptanoin, in the treatment of an individual having a lysosomal storage disease, including Pompe disease....  
WO/2020/037372A1
A method of detecting the presence of an NBOMe in a sample which comprises of contacting the sample with an activated p-quinone such as 2,3,5,6-tetrachloro-1,4-benzoquinone (TCBQ) and an aldehyde, for example acetaldehyde, and optionally...  
WO/2020/025781A1
The present invention relates to a cocrystal of ubiquinone and a hydrogen bond donor coformer, to a process for the preparation thereof, and to its use as a medicament or a dietary supplement. The invention also relates to compositions c...  
WO/2020/015316A1
Disclosed are a method for extracting and purifying coenzyme Q10 and coenzyme Q10 prepared thereby. The method extracts and purifies coenzyme Q10 from coenzyme Q10 bacteria and comprises the steps of extracting, precipitating, decoloring...  
WO/2020/014776A1
An oral dispersible film composition comprising at least one active ingredient and a film forming agent, as well as a method of manufacture of same. The oral dispersible film composition can be free of gum resin, and can be utilized to a...  
WO/2019/231735A1
Provided are colored 1,4-benzoquinone compounds obtained by oxidation of precursor molecules from the venom of the scorpion Diplocentrus melici (Diplocentridae family). Schemes for the chemical synthesis of these compounds using reagents...  
WO/2019/222146A1
In some embodiments of the invention, inventive compounds (e.g., Formula (I), (IA), (II), and (III), and urolithin derivatives) are disclosed. Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inve...  
WO/2019/201819A1
The present invention relates to the oxidation of alkylated p-hydroquinones. It has been found the oxidation by oxygen or an oxygen containing gas mixture in the presence of a transition metal salt, which does not comprise any polydentat...  
WO/2019/201820A1
The present invention relates to the oxidation of alkylated p-hydroquinones. It has been found the oxidation by aqueous hydrogen peroxide in the presence of a transition metal salt, which does not comprise any polydentate ligand bound to...  
WO/2019/157437A9
We disclose quinone compounds and related species (Formula I) that possess significant advantages when used as a redox active material in a battery, e.g., a redox flow battery. In particular, the compounds provide redox flow batteries (R...  
WO/2019/178689A1
A method for promoting weight management in a mammal is provided, comprising administering to the mammal a composition comprising at least one weight loss agent and at least one mitochondria enhancing agent. The weight loss agent may be ...  
WO/2019/158615A1
The present invention relates to novel lignin-derived compounds and compositions comprising the same and their use as redox flow battery electrolytes. The invention further provides a method for preparing said compounds and compositions ...  
WO/2019/157437A1
We disclose quinone compounds and related species (Formula I) that possess significant advantages when used as a redox active material in a battery, e.g., a redox flow battery. In particular, the compounds provide redox flow batteries (R...  
WO/2019/157163A1
[(2E)-2-[(3-methoxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)met hylidene]-N,N-diethylpentanamide] (APX2009) and (2E)-2-[(3-methoxy-1,4-dioxo-1,4-dihydronapthalen -2-yl)methylidene]-N-methoxypentanamide] (APX2014) for inhibiting ocular disea...  
WO/2019/148282A1
The present disclosure concerns methods and formulations for delivery of hydrophobic agents (such as ubiquinone or poorly soluble drugs) for therapeutic and bioanalytical use. It further concerns use of lipopeptides (e.g. caspofungin) or...  
WO/2019/128060A1
The present application relates to a method for extracting a coenzyme Q10 and phospholipids from a coenzyme Q10 fermentation bacterial powder. The method is characterized in that a mixed solvent having a three-dimensional Hansen solubili...  
WO/2019/123144A1
The present invention provides the use of vitamin K2 compositions for the treatment of drug- induced neuropathy. More particularly it is related to the use of vitamin K2-7 compositions for the treatment of drug- induced peripheral neurop...  
WO/2019/071353A1
A method of reducing glutamate efflux from skeletal muscle by inhibiting system Xc- activity is provided. The method is useful for the treatment of statin-induced myalgia. Pharmaceutical compositions useful to treat statin-induced myalgi...  
WO/2019/052477A1
Provided is the use of a class of tanshinone compounds for treating hemangioma; in particular, provided is the use of a class of compounds as shown in formula I below or a pharmaceutically acceptable salt thereof. The tanshinone compound...  
WO/2019/028933A1
The present invention relates to the technical field of pharmaceuticals, and discloses an antibacterial application of a Dryopteris fragrans phloroglucinol compound flavaspidic acid BB. The present invention provides for the first time a...  
WO/2019/009157A1
[Problem] Conventional polymerization inhibitors are used to capture radicals generated, for example, during storage of a radical polymerizable compound, thus allowing the radical polymerizable compound to be safely handled. However, the...  
WO/2018/214814A1
A use of an aminomethylenecyclohexane-1,3-dione compound. In particular, the present invention relates to a use of a compound shown in the following formula (I) or a pharmaceutically acceptable salt thereof alone or in combination with o...  
WO/2018/191789A1
The invention relates to compounds of Formula (I) and methods for their preparation. Also described are pharmaceutical compositions comprising a compound of Formula (I) and their use in the treatment or prevention of conditions associate...  
WO/2018/161482A1
A carbon nitride-based photocatalyst and a preparation method therefor, wherein the photocatalyst is prepared by reacting melcimide with 3,3,,4,4, ­­­­­­­benzophenone tetracarboxylic dianhydride, such that the energy levels of the...  
WO/2018/145660A1
The present invention relates to a fully continuous flow synthesis process for use with 2-methyl-1,4-naphthoquinone and an integrated continuous flow reactor for use in achieving said process; the synthesis process uses 2-methylnaphthale...  
WO/2018/136266A1
Compositions for use in treating and/or alleviating a symptom of inflammatory bowel disease, colitis, and/or enterocolitis in a subject in need thereof are disclosed. The composition comprises a therapeutically effective amount of an ant...  
WO/2018/130865A1
A composition for treating headaches and migraines and methods of using same for preventative use to decrease the frequency, duration and severity of headaches and migraines in children and adults.  
WO/2018/062193A1
Provided is a monomer composition in which the polymerization inhibitor solubility in ring-structured monomer is excellent, the ring-structured monomer stability during storage is excellent, and the ring-structured monomer may be easily ...  
WO/2018/045424A1
The invention relates to terpenes and uses thereof.  
WO/2018/044150A1
The present invention relates to a method for producing demethylbelamcandaquinone B from Labisia pumila and use thereof. The method is characterized by the steps of obtaining an extract from Labisia pumila plant material using water extr...  
WO/2018/007198A1
The present invention relates to the preparation of Thapsigargin (1) and Nortrilobolide (2). The invention further relates to intermediates and preparation of said intermediates which are useful for the preparation of (1) and (2).  
WO/2017/222996A1
Provided herein are compounds, compositions and method of using thereof to treat or prevent malaria.  
WO/2017/193986A1
The present invention relates to a benzyl bisphenol derivative, and a preparation method and pharmaceutical application thereof. The benzyl bisphenol derivative provided by the invention can promote a sedative-hypnotic effect, offer brai...  
WO/2017/151111A1
Improved systems and methods for producing synthetic hypericin at high volume and high purity.  
WO/2017/145814A1
This quinone derivative is a compound represented by general formula (1). In general formula (1), R represents an optionally substituted alkyl group having 1-6 carbon atoms, an optionally substituted aryl group having 6-14 carbon atoms, ...  
WO/2017/145759A1
Provided is a quinone derivative represented by general formula (1). In general formula (1), R1 represents a group selected from the group consisting of an optionally substituted alkyl group having 1-8 carbon atoms, an aryl group that ha...  
WO/2017/145716A1
In this production method according to the present disclosure, a 1,1'-binaphthyl derivative precursor having, at each of the 2-position and 2'-position of a 1,1'-binaphthyl skeleton, an electron-donating group including an oxygen atom di...  
WO/2017/105682A1
A phenylene ether oligomer is prepared by a process that includes partially converting 2,6-dimethylphenol to 3,3',5,5'-tetramethyl-4,4'-dihydroxybiphenyl and/or 3,3',5,5'-tetramethyldiphenoquinone, converting the residual 2,6 dimethylphe...  
WO/2017/106624A1
Provided herein are naphthoquinones compounds such as those with a hydrogen bond donating group of the formula (I): wherein: R1, R2, R3, R4, R5, and n are as defined herein. Also provided herein are pharmaceutical composition of the pres...  
WO/2017/106803A1
Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases o...  

Matches 1 - 50 out of 2,428