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WO/2019/239341A1 |
The invention relates to a process for the asymmetric synthesis of (R)-4-propyldihydrofuran-2(3H)-one starting with trans-2-hexen-l-al and nitromethane, wherein the stereocentre is generated for the first time by an organocatalytic metho...
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WO/2019/217536A9 |
Compositions that include a bupivacaine salt are provided. The compositions may include bupivacaine linoleate, bupivacaine linolenate or bupivacaine laurate, at least one thermosensitive polymer, and at least one mucoadhesive or dermoadh...
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WO/2019/229857A1 |
A method is provided of producing acetic acid with excellent potassium permanganate test values in an industrially efficient manner and without incurring high costs. This acetic acid production method involves a step in which (1) acetald...
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WO/2019/229856A1 |
A method is provided of producing acetic acid with excellent potassium permanganate test values in an industrially efficient manner and without incurring high costs. A distillation column (a crotonaldehyde removal column) which sets the ...
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WO/2019/229859A1 |
A method is provided of producing acetic acid with excellent potassium permanganate test values in an industrially efficient manner and without incurring high costs. This acetic acid production method involves: a carbonylation reaction s...
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WO/2019/230007A1 |
A method is provided of producing acetic acid with excellent potassium permanganate test values in an industrially efficient manner and without incurring high costs. This acetic acid production method involves a step in which (1) acetald...
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WO/2019/229858A1 |
A method is provided of producing acetic acid with excellent potassium permanganate test values in an industrially efficient manner and without incurring high costs. An aldehyde separation and removal step involves a step in which acetal...
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WO/2019/220522A1 |
Provided is a method with which it is possible to reduce the concentration of formic acid in produced acetic acid via simple means. The acetic acid production method according to the present invention comprises, in a process for producin...
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WO/2019/211904A1 |
An acetic acid production method is provided which can greatly improve the service life of a silver-substituted ion exchange resin (IER) for removing organic iodine compounds in the acetic acid. In this acetic acid production method, in ...
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WO/2019/212072A1 |
The present invention relates to an acetic acid production method using carbon dioxide and a system for same, which can produce methanol and acetic acid in a single process, thereby significantly reducing the time required for the produc...
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WO/2019/186697A1 |
Provided are: a method whereby it becomes possible to effectively prevent the local corrosion of a vessel wall of a process unit and/or a process line and reduce the concentration of formic acid in a product acetic acid; and a method for...
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WO/2019/183549A1 |
A method of producing acetic acid, the method comprising: reacting methanol and/or methanol derivatives with carbon monoxide in the presence of a liquid reaction medium under carbonylation conditions to form, a carbonylation product comp...
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WO/2019/178677A1 |
The present disclosure relates to the targeted delivery of defined active agents and/or immunomodulatory agents to lymph nodes or lipoid cells in a lymphatic tissue. More particularly, the invention provides methods for targeted delivery...
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WO/2019/183541A1 |
A method comprising: contacting methanol with carbon monoxide in the presence of a liquid reaction medium under carbonylation conditions to form a carbonylation product comprising acetic acid; separating the carbonylation product into a ...
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WO/2019/159652A1 |
Provided is a novel perfluoro diacyl peroxide. The perfluoro diacyl peroxide is characterized by being represented by formula (1): (C5F11COO)2 (1).
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WO/2019/141634A1 |
The invention relates to a method for producing carbon monoxide using a formic acid derivative, particularly an alkyl formate. It also relates to a method selected from the method for producing methanol, the method for producing acetic a...
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WO/2019/127994A1 |
The present invention relates to a sacubitril sodium salt as represented by formula IV, a eutectic of sacubitril free acid and acetic acid, a crystal form of the eutectic and a preparation method for the crystal form, and a method for us...
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WO/2019/123126A1 |
The present disclosure relates to a process for the manufacturing of a 3-5 halopropionylhalide, wherein the process comprises the steps of: a) providing a flow reactor comprising a reaction chamber; b) providing reactants comprising: i. ...
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WO/2019/099750A9 |
Provided herein are compositions, methods, systems and/or kits for preventing and/or treating neoplasms using at least one modulator selected from quercetin, sodium phenyl butyrate and epigallocatechin-3-gallate in combination with one o...
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WO/2019/113435A1 |
The disclosure provides a process for preparing a compound of formula (I) or a pharmaceutically acceptable salt thereof.
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WO/2019/100602A1 |
Relating to an experimental animal model, disclosed are a method for constructing an animal model for ulterative colitis and an application thereof. The animal model for ulcerative colitis uses the Chinese field dog as a model animal and...
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WO/2019/101856A1 |
The present invention relates to a process of preparation of carboxylic acids by oxidative cleavage of at least one vicinal diol or an epoxide in the presence of an oxidant comprising molecular oxygen and a heterogeneous catalyst compris...
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WO/2019/080155A1 |
The present invention relates to a conjugate salt of N,N-dimethylglycine and a metal organic acid, a preparation method therefor, and an application thereof. The conjugate salt of N,N-dimethylglycine and a metal organic acid has the foll...
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WO/2019/080009A1 |
Disclosed are an N,N-dimethylglycine organic acid polyvalent metal ion compound salt or a solvate thereof, and an application thereof in preparation of novel feed additives and feeds. Also disclosed is a feeding composition comprising th...
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WO/2019/061213A1 |
Disclosed is a method for preparing a sodium acetate, which method comprises the following steps: an acid-base neutralization reaction; filtration, which involves introducing a reaction solution into a filter, the interior of which is pr...
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WO/2019/067063A1 |
This disclosure relates to neo-acids of formula (F-l) and processes for their preparation from a vinylidene olefin using Koch chemistry.
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WO/2019/061358A1 |
A method for directly producing methyl acetate and/or acetic acid from syngas, the reaction process being completed in at least two reaction zones, the method comprising: causing a raw material containing syngas to enter a first reaction...
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WO/2019/043238A1 |
The present invention concerns a process and intermediates for the manufacture of difluoro acetyl chloride. The invention further concerns a process for the manufacture of an agrochemically or pharmaceutically active compound, which comp...
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WO/2019/039648A1 |
The present invention relates to a heterogeneous catalyst for producing acetic acid by methanol carbonylation, characterized in that a rhodium complex ion is ionically bonded to an insoluble catalyst support having a quaternary pyridine ...
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WO/2019/035715A1 |
The invention is directed to a method of electrochemically producing valeric acid. The method of the invention comprises - contacting a solution of levulinic acid with an anode and a cathode in an electrochemical cell; and - electrochemi...
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WO/2019/006149A1 |
The present disclosure provides for a method for measuring the concentration of one or more components in a feed stream or reactor mixture of a process for producing acetic acid by both infrared and Raman spectroscopic analyses. In some ...
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WO/2019/002240A1 |
The present invention pertains to a process for recovering acetic acid from an aqueous stream containing acetic acid, comprising the steps of (a) contacting the aqueous stream with tri-n-octylamine and 1-undecanol, with the weight ratio ...
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WO/2019/005633A1 |
There is disclosed a process for the separation of long chain dibasic acid and fatty acid, comprising: (1) reacting a mixture of long chain dibasic acid and fatty acid with ammonium hydroxide to form an insoluble ammonium salt of fatty a...
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WO/2018/235094A1 |
The instant disclosure provides a process for synthesis of compound of Formula: wherein Mz+ is a transition metal ion and X and Y are carboxylate anions. The catalysts are hydrocarbon soluble and the process for their preparation, as dis...
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WO/2018/234999A1 |
Processes for producing a disubstituted oxalate are disclosed. The process includes contacting a mixture of cesium salt and gamma alumina with one or more alcohols and carbon dioxide (CO2) under reaction conditions sufficient to produce ...
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WO/2018/222785A1 |
Porous calcium lactate metal-organic frameworks (MOFs) comprise non-toxic metal ions - Ca(II) and non-toxic, renewable and cheap linkers - lactate and acetate. The MOFs are nontoxic and environmentally-benign, and can be used as degradab...
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WO/2018/215418A1 |
The present invention concerns a method for preparing a compound of formula (I) HR1R2C-CF2-(C=0)-Y from a compound of formula (II) R1C2C=CX-(C=O)-Y or formula (III) HR1R2C-CX1X2-(C=O)-Y brought into contact with hydrofluoric acid; R1 and...
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WO/2018/214089A1 |
A method for preparing 2-propylheptanoic acid. The method comprises the following steps: step 1) mixing, in parts by weight, 100 parts of sodium hydroxide, 500-800 parts of 2-propylheptanol, and 1-20 parts of a catalyst for reaction for ...
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WO/2018/209842A1 |
Disclosed in the present invention is a trifluoroacetic acid synthesis process, the preparation process comprising: placing a solid catalyst in a fixed bed; using a steady-state pump to pass hydrogen peroxide through same; raising to a f...
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WO/2018/199665A1 |
The present invention relates to a system and a method for converting carbon dioxide using a liquid-liquid interface and an electron donor-acceptor catalyst, the system producing a carbon compound and hydrogen gas by reducing carbon diox...
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WO/2018/197539A1 |
The present invention concerns a process for the reduction of content of carboxylic acids and derivatives thereof in oleum, disulfuric acid or concentrated sulfuric acid. The invention further concerns a process for the manufacture of ca...
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WO/2018/191789A1 |
The invention relates to compounds of Formula (I) and methods for their preparation. Also described are pharmaceutical compositions comprising a compound of Formula (I) and their use in the treatment or prevention of conditions associate...
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WO/2018/187852A1 |
Compositions and methods for providing a person with an exogenous and therapeutically effective supply of ketones are disclosed. The compositions may consist essentially of (a) purified butyrate (or esters or propionate salts thereof) an...
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WO/2018/191263A1 |
The present disclosure provides for a method for measuring the concentration of one or more components in a reactor or a separation unit of an acetic acid process by Raman spectroscopic analyses. In some embodiments, the conditions in th...
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WO/2018/178693A1 |
A quaternary ammonium salt of formula (I): wherein X is a linking group; Y is O, NH or NR1 wherein R1 is H or an optionally substituted hydrocarbyl group; Q+ is a moiety that includes a quaternary ammonium cation; A- is an anion; R2 is a...
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WO/2018/179457A1 |
Provided is a method capable of efficient industrial production of high quality acetic acid with good potassium permanganate test value and low impurity content, without incurring enormous cost. This acetic acid production method compris...
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WO/2018/181907A1 |
Provided are a novel carbonyl group-containing sulfonic acid and carboxylic acid, and salts thereof. The present invention is a compound represented by the formula: R1-C(=O)-(CR2 2)n-(OR3)p-(CR4 2)q-L-A (In the formula, R1 is an optional...
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WO/2018/173307A1 |
The purpose of the present invention is to provide a method for industrially effectively producing, without significant cost, acetic acid which has a good potassium permanganate test value. The present invention provides a method includi...
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WO/2018/165283A1 |
A method of making acrylic acid in liquid phase by contacting a feed stream containing lactic acid, lactide, or mixtures thereof with a molten salt catalyst comprising a protic ionic liquid (PIL), which contains a bromide anion (Br-), is...
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WO/2018/163449A1 |
Provided is a method whereby acetic acid that exhibits good results in a potassium permanganate test can be produced efficiently in an industrial manner without involving excessive cost. This method for producing acetic acid includes a c...
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