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JP2013100324A |
To provide a form of compound, which can facilitate manufacturing processes for therapeutic dosage forms.This invention relates to: an organic acid salt of compound (1) and/or its tautomers and solvates thereof; composition comprising a ...
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JP2013095722A |
To provide a method for synthesizing oxalic acid from carbon dioxide in a high yield.The method for synthesizing oxalic acid comprises: (A) allowing a metal complex, which includes a metal atom, a nitrogen-containing compound having thre...
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JP2013079237A |
To provide a complex as a redox mediator.A complex of formula II is used as a redox mediator. In the formula, M is ruthenium or osmium in an oxidation state of 0, 1, 2, 3 or 4; x and n are each independently an integer selected from 1-6;...
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JP5179628B2 |
New platinum(IV) complexes which has a strong antitumor activity and has a feature that a side effect is relatively reduced is provided. The new complex is platinum(IV) complexes with cis,cis-spiro[4,4]nonane-1,6-diamine ligand and is pl...
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JP5172820B2 |
This invention relates to a method for producing a carboxylic acid chloride, which efficiently decomposes a Vilsmeier reagent type compound in a carboxylic acid chloride lacking a thermal stability or a carboxylic acid chloride hardly di...
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JP5168072B2 |
To provide a dicarboxylic acid suitable for a method producing polyester with an objective molecular weight in an industrially advantageous and effective producing method. The dicarboxylic acid contains sulfur and nitrogen atoms in the w...
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JP5166668B2 |
Ionic compounds with a freezing point of up to 100° C. are formed by the reaction of an one amine salt of formula (I) R1R2R3R4N+X-, such as choline chloride with an organic compound (II) capable of forming a hydrogen bond with X; such a...
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JP5140442B2 |
A polyalkenyl succinic anhydride is prepared with low amounts of resinous or chlorinated byproducts in a two-step process whereby a polyalkene is first reacted with an unsaturated organic acid in a thermal ene reaction, followed with exp...
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JP2013023464A |
To provide a method for producing a high-purity succinic acid which inhibits a by-product of a malic acid.In the method for producing the succinic acid, hydrogenation reaction is performed by incorporating an aqueous solvent and a noble ...
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JP5120596B2 |
A battery capable of improving the cycle characteristics is provided. The battery includes a cathode, an anode, and an electrolytic solution. The electrolytic solution is impregnated in a separator provided between the cathode and the an...
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JP5113210B2 |
The invention is directed to a process for producing intermediates of a compound which exhibits an activated blood coagulation factor Xa inhibitory action and which is a useful preventive and a therapeutic agent for thrombotic diseases. ...
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JP2012246271A |
To provide a method for producing oxalic acid, capable of mass-producing oxalic acid in high yield, while excellent in stability and certainty of treatment, initial cost, running cost and the like, by a simplified and facilitated steps a...
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JP2012240934A |
To provide a method for producing oxalic acid for allowing its mass production industrially in high yield while achieving stable and sure treatment and good initial cost, running cost and the like by relatively simple process and product...
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JP2012530737A |
The present invention is directed to a manufacturing process for 1,2-diamino-cyclohexane-platinum(II) complexes, specifically to a manufacturing process for oxaliplatin. The process is straightforward, economical and applicable to indust...
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JP5089989B2 |
The present invention relates to compounds that selectively bind to cells undergoing perturbations and alterations of their normal plasma membrane organization, such as cells undergoing apoptosis or activated platelets. The invention fur...
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JP2012229174A |
To provide a process for producing oxalic acid capable of producing oxalic acid in a high yield and in a large quantity thereby achieving significant reduction in cost while being excellent in process stability, reliability, initial cost...
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JP5076269B2 |
The present invention provides a method for obtaining a compound useful as a raw material for various fluororesins in high yield by a short process by using a starting material which is inexpensive and readily available. Namely, the pres...
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JP5069905B2 |
The present disclosure relates to novel cocrystals and novel methods for cocrystallization. In particular, the disclosure includes cocrystals comprising a salt of an active agent, such as a chloride salt of an active pharmaceutical ingre...
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JP5069829B2 |
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JP2012201685A |
To provide a method for producing α,ω-dicarboxylic acids and their esters.The method includes: (a) a process of ozonolysing unsaturated fatty acids or unsaturated acid derivatives, and (b) a process of oxidizing the reaction mixture ob...
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JP5052234B2 |
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JP5052362B2 |
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JP5047441B2 |
A process for producing compounds of formula (VIIa) and (VIIb) wherein X is a leaving group; Y and Y<1 >are idependently Cl or Br; and Z is Cl, Br or a haloalkyl group which process comprises a) reacting a compound of formula (VII) where...
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JP2012180306A |
To provide a method for efficiently and stably producing an aliphatic dicarboxylic acid crystal having a large surface area and high acicularity making the composition to slurry easily.This method for producing the acicular aliphatic dic...
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JP5030175B2 |
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JP5013879B2 |
A method is disclosed for the recovery of an organic acid from a dilute salt solution in which the cation of the salt forms an insoluble carbonate salt. A tertiary amine and CO2 are introduced to the solution to form the insoluble carbon...
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JP4993959B2 |
An aqueous solution containing an organic acid chromium (III) salt represented by general formula: Cr m (A x ) n , wherein A represents a residue left after proton removal from an organic acid; x represents a charge of A; and m and n rep...
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JP2012140424A |
To provide compounds that selectively bind to cells undergoing perturbations of the normal organization of cell plasma membranes.The compounds are represented by the structure as set forth in the formula (II), including pharmaceutically ...
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JP4983861B2 |
To produce a cadaverine aliphatic dicarboxylate salt by a simpler production process in high reaction yield, at high production speed and at high purity. The process for producing the cadaverine aliphatic acid dicarboxylate salt is to co...
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JP2012516330A |
The invention provides polypeptide-platinum conjugates comprising an anti-cancer platinum complex conjugated to polypeptides that bind relatively specifically to cancer cells, so as to direct the conjugates to cancer cells resulting in i...
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JP2012515795A |
Methods for producing biosourced dodecanedioic acid and compositions comprising biosourced dodecanedioic acid are provided. In some embodiments, the method comprises first forming muconic acid biologically from a renewable carbon source,...
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JP4961821B2 |
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JP4942645B2 |
A method oxidizes an organic compound with oxygen in the presence of a catalyst, in which the catalyst contains a N-hydroxy- or N-(substituted oxy)-imide compound derivable from at least one selected from a target product, a reaction int...
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JP4937637B2 |
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JP4931210B2 |
There are provided organic acid anion containing aluminum salt hydroxide particles represented by the following general formula (I): M a [Al 1-x M' x ] b A z B y (OH) n ·mH 2 O(I) (whe...
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JP4932740B2 |
The invention relates to a method of controlling a hydrogenation of a starting material in a hydrogenation reactor, in which the amount of hydrogen reacted in the hydrogenation is firstly determined, the ratio of the amount of hydrogen r...
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JP2012087085A |
To provide a method of producing a high-purity niobium solution, in which the high-purity niobium solution having lower impurities can be obtained by a simple operation.The method of producing the high-purity niobium solution includes: a...
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JP2012510491A |
A process for the manufacture of adipic acid carried out in devices made of material resistant to the corrosion of the synthesis medium is described. A process for the manufacture of adipic acid carried out in devices, some of which are ...
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JP2012077068A |
To provide a barium titanyl oxalate particle having fine and spherical particle shape and to provide barium titanate having excellent crystallinity.The barium titanyl oxalate particle is characterized to have an average particle diameter...
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JP4918751B2 |
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JP4916051B2 |
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JP4913317B2 |
This invention is directed to a new low molecular weight branched alkenyl succinic acid derivative that may be prepared by reacting a low molecular weight polyisobutene (PIB) having from about 8 to about 32 carbon atoms, and wherein at l...
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JP2012508215A |
The present invention relates to salts, polymorphs and hydrates of 2-Amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diol, and to the use thereof, in particular in the treatment or prevention of various autoimmune conditions.
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JP4897676B2 |
A method of immobilising a target molecule on a substrate, which comprises exposing the target molecule to the substrate in the presence of a metal complex, wherein the target molecule is an unmodified target molecule, and wherein the me...
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JP4898009B2 |
Raney copper which is doped with at least one metal from the group comprising iron and/or noble metals is used as a catalyst in the dehydrogenation of alcohols.
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JP4884375B2 |
The present invention relates to a novel method for the production of long-chained quaternary ammonium oxalates and of long-chained quaternary ammonium hydrogen oxalates by reacting amines with dimethyl carbonate and further reacting the...
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JP4874253B2 |
The present patent application encompasses a method of determining characteristic numbers for catalyst material by means of electrochemical measurement, the use of this method for optimization and selection of catalysts and processes.
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JP4873400B2 |
To provide a method for oxidizing a new olefin by using a supercritical carbon dioxide and an ionic liquid as a reaction site. The method for oxidizing an olefinic hydrocarbon comprises synthesizing a carbonyl compound, an epoxide compou...
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JP4853691B2 |
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JP4842819B2 |
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