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Matches 101 - 150 out of 4,617

Document Document Title
WO/2012/148108
The present invention relates to a method for preparing lactide from alkyl lactate, comprising: a step of polymerizing alkyl lactate under a lead (Pb)-based catalyst so as to prepare lactic acid oligomers; and a step of depolymerizing sa...  
WO/2012/146604
The invention relates to process for the continuous production of 4- chloroacetoacetyl chloride, comprising the steps of (a) feeding diketene and chlorine into a thin film reactor and (b) reacting the diketene and chlorine to obtain 4-ch...  
WO/2012/148108
The present invention relates to a method for preparing lactide from alkyl lactate, comprising: a step of polymerizing alkyl lactate under a lead (Pb)-based catalyst so as to prepare lactic acid oligomers; and a step of depolymerizing sa...  
WO/2012/142983
Diastereomeric salts of the compound of formula I with D-(-)-mandelic and R-(-)-3- chloromandelic acid, a method of for the preparation thereof and their use in the synthesis of the drug ticagrelor.  
WO/2012/140276
A new process for preparing calcium salts of 3-hydroxy-3-methylbutyric acid is described. Lactones obtained from ketene and acetone are hydrolyzed in selective and scalable manners. The 3-hydroxy-3-methylbutyric acid or its calcium salts...  
WO/2012/140276
A new process for preparing calcium salts of 3-hydroxy-3-methylbutyric acid is described. Lactones obtained from ketene and acetone are hydrolyzed in selective and scalable manners. The 3-hydroxy-3-methylbutyric acid or its calcium salts...  
WO/2012/140276
A new process for preparing calcium salts of 3-hydroxy-3-methylbutyric acid is described. Lactones obtained from ketene and acetone are hydrolyzed in selective and scalable manners. The 3-hydroxy-3-methylbutyric acid or its calcium salts...  
WO/2012/140243
The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.  
WO/2012/136221
There is provided novel fluoro-substituted compounds capable of modulating the G- protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatme...  
WO/2012/136568
The invention relates to a method for the removal of the cyclic diester of a 2-hydroxy alkanoic acid from a vapor containing said diester, wherein the vapor is contacted with an aqueous solution so that the diester dissolves in said solu...  
WO/2012/131299
A process for the production of a quaternary ammonium salt of lactic acid, comprising contacting at least one saccharide with at least one water-soluble quaternary ammonium hydroxide, is provided. Also provided are processes for the prod...  
WO/2012/129473
The present invention provides complexes of gallium with a ligand, methods of making the complexes, methods of using the complexes and pharmaceutical gallium compositions comprising the complexes, in particular those compositions suitabl...  
WO/2012/116820
A process is specified for obtaining organic carboxylic acids from aqueous mixtures, for example fermentation broths, comprising the following steps: A) providing the aqueous mixture with a pH of 1 to 10, B) contacting the aqueous mixtur...  
WO/2012/111577
A carotenoid-containing composition which comprises: a carotenoid component that contains at least one crystalline carotenoid, at least 90 mass% of the crystalline carotenoid being present in an amorphous state; a (poly)glycerol fatty ac...  
WO/2012/112492
This invention relates to novel derivatives of 4-hydroxybutyric acid and prodrugs thereof, and pharmaceutically acceptable salts of the foregoing. This invention also provides pharmaceutical compositions comprising a compound of this inv...  
WO/2012/108300
Silica-based chiral nanostructures each comprising or obtained from a silica/organic-substance composite having chirality are provided, the nanostructures being obtained through a step in which an aqueous solution of a polymer having a l...  
WO/2012/103813
The present invention provides Danshensu derivatives containing a moiety of Chuanxiongqin (tetramethylpyrazine), and pharmaceutical compositions containing the Danshensu derivatives or their salts and pharmaceutically acceptable carriers...  
WO/2012/099139
Provided are: a process for producing high-purity ferric citrate that contains substantially no β-oxidized iron hydroxide; high-purity ferric citrate that contains substantially no β-oxidized iron hydroxide; and use of the ferric citra...  
WO/2012/097427
New uses for phenylketone carboxylate compounds and substituted aromatic compounds of Formula I, Formula I.1, Formula I.2, Formula IA, Formula IB, Formula IC and Formula II and their pharmaceutical acceptable salts for the treatment of c...  
WO/2012/091570
A carbohydrate-containing feedstock is converted in a process, which process comprises contacting the feedstock in a first step with an alcohol in the presence of a first acid catalyst at a temperature below 100 °C to yield an intermedi...  
WO/2012/089181
The compounds of general formula II are new and represent important intermediates in the synthesis of tapentadol. In the synthesis of tapentadol of formula I and its pharmaceutically acceptable salts, O-protected (2R,3R)-acids of general...  
WO/2012/088607
Disclosed is a process for preparing a treprostinil salt. The process involves the step of dissolving treprostinil in a water-miscible organic solvent to form a treprostinil solution. The treprostinil solution is reacted with an aqueous ...  
WO/2012/092253
Green compositions and technologies are provided. In an embodiment, the present invention provides a method of separating a first material from a second material. For example, the method can comprise mixing the first material and the sec...  
WO/2012/092253
Green compositions and technologies are provided. In an embodiment, the present invention provides a method of separating a first material from a second material. For example, the method can comprise mixing the first material and the sec...  
WO/2012/085361
The invention relates to a process for converting cellulose or lignocellulosic biomass using tin- and/or antimony-based stable non-zeolite heterogeneous catalysts, preferably dispersed on a support. The use of these catalysts makes it po...  
WO/2012/085191
The present invention relates to a novel form of pravastatin, notably pravastatin sodium, and a method for the preparation of a novel form of pravastatin.  
WO/2012/082837
The present invention relates to a method of making indeno-fused naphthol materials, that involves, with some embodiments, forming an indanone acid intermediate, which can be represented by the following general Formula V, [Formula V] Wi...  
WO/2012/081723
In order to construct a synthetic pathway of a compound without any limitation on chemical transformation rules, this synthetic pathway constructing equipment is provided with: a conversion section for converting the chemical structures ...  
WO/2012/080465
The present invention generally relates to controlling the viscosity ofwater-based mud systems. More particularly, the present invention relates to methods and compositions for thinning and deflocculating aqueous based fluids used in wel...  
WO/2012/078147
A process for preparing 4-[(2R)-2-X-methyl)-3-methylbutyl]-1 -methoxy-2-3(3- methoxypropoxy)-benzene wherein X is a leaving group and use of this compound in the synthesis of aliskiren.  
WO/2012/071766
A preparation method of L-arginine-α-ketoglutarate by direct crystallization from zymotic fluid is provided. The method includes: respectively pretreating L-arginine zymotic fluid and α-ketoglutaric acid zymotic fluid by flocculation, ...  
WO/2012/069004
Disclosed are a preparation method for a key intermediate of tapentadol: (1R, 2R)-1-ethyl-2-methylbenzene ethane compound, and a method for applying the key intermediate in the preparation of tapentadol and a derivative thereof.  
WO/2012/069419
Compounds of general formula (I), their use as calcium receptor-active compounds for the prophylaxis, treatment or amelioration of physiological disorders or diseases associated with disturbances of CaSR activity, such as hyperparathyroi...  
WO/2012/069423
The invention relates to a method for the preparation of 2-(6'-methoxy-2'-naphthyl)propionic acid chloride(naproxen chloride) using phosgene, and a method for the preparation of esters and amides derived from the thus prepared naproxen c...  
WO/2012/069176
The invention relates to a terpene ether of the general formula (I) Z-O-R, in which Z denotes a bicyclo[a, b, c]heptenyl group or bicyclo[a, b, c]heptyl group, wherein: a + b + c = 5, a = 2, 3 or 4, b = 2 or 1, and c = 0, 1, said group b...  
WO/2012/066366
The invention relates to non-sulfonic acid type new rasagiline salts, a process for the preparation thereof, pharmaceutical compositions containing said salts and the use thereof for the treatment or prophylaxis of various diseases, name...  
WO/2012/062041
Disclosed are aromatic ketone compounds with para- or meso-substituted multifunctional groups as represented by the general formulae I-III, preparation methods thereof, and free-radical polymerization photoinitiators comprising the compo...  
WO/2012/065002
A method of synthesizing lactic acid and lactate is invented from carbohydrates, such as monosaccharides and/or polysaccharides in the presence of the catalyst that is the combinations of nitrogen-heterocycle aromatic ring cation salts a...  
WO/2012/059933
The present invention relates to an improved and commercially, viable process for the resolution of racemic cis milnacipran of formula I and its pharmaceutically acceptable salts of formula II. The present invention comprises using racem...  
WO/2012/060387
Novel compounds represented by formula (I) are useful for preventing or treating diseases caused by protozoans. Use is made of one or more members selected from among compounds represented by formula (I), optical isomers thereof and phar...  
WO/2012/055014
Phenylketone carboxylate compounds of Formula I, wherein n=2-6; R=C(0); -OC(O)- or -CH( OH)-; A is (CH2)mCOOH, W(CH2)mCOOH or YCH(COOH)((CH2)pCH3) when B is Ft B is (CH2)mCOOH, W(CH2)mCOOH or YCH(COOH)((CH2)pCH3) when A is Ft or A snd B ...  
WO/2012/056318
The present invention deals with a method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway comprising the transformation of malate in 4-phospho-malate using a malate kinase, said 4- phospho-malate being transformed...  
WO/2012/051774
Disclosed is a process for salting out and extracting organic acid from a fermentation broth, which is characterized by adding a dissoluble inorganic or organic salt and an extractant into the organic acid fermentation broth, stirring fo...  
WO/2012/053232
The anti-Leishmania compound represented by formula (3).  
WO/2012/054314
Waterborne coating compositions are disclosed that include a latex emulsion polymer, and, as a coalescent, a levulinic acid ester of a monohydric aliphatic alcohol having from 10 to 20 carbon atoms. The coating compositions of the invent...  
WO/2012/052703
A process for the production of a complex of lactic acid and either ammonia or an amine, comprising reacting one or more saccharides with barium hydroxide to produce a first reaction mixture comprising barium lactate, and contacting at l...  
WO/2012/046787
The purpose of the present invention is to provide a diene-based carboxylate anion, and salt thereof, which has a specific structure and is a previously unstudied novel compound, and furthermore to provide a diene-based carboxylate anion...  
WO/2012/047251
Low molecular weight gelators, methods of making such gelators, organogels comprising such gelators and systems and methods of using such gelators for the containment and/or remediation of a release and/or spill of a crude oil, a petrole...  
WO/2012/042534
The present invention relates to the synthesis of R-sitagliptin. The present invention also relates to a compound of formula (IV) or its salt, that are useful as key intermediate in the synthesis of R-sitagliptin or pharmaceutically acce...  
WO/2012/042534
Provided is preparation method of R-sitagliptin. Compound of formula (IV), amine salt thereof and method for preparation thereof are also provided. Said compound of formula (IV) or amine salt thereof is useful as key intermediate in the ...  

Matches 101 - 150 out of 4,617