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Matches 101 - 150 out of 9,875

Document Document Title
WO/2014/177464A2
The invention relates to inhibitors of the NHR2 tetramerization and their use as tumor therapeutics (e.g. against acute myeloid leukemia (AML)), cytostatics, and diagnostic agents.  
WO/2014/178931A8
Methods of treating a subject having or at risk of developing a neurodegenerative disease or condition associated with demyelination, insufficient myelination, or underdevelopment of myelin sheath are described. The methods include admin...  
WO/2014/177464A3
The invention relates to inhibitors of the NHR2 tetramerization and their use as tumor therapeutics (e.g. against acute myeloid leukemia (AML)), cytostatics, and diagnostic agents.  
WO/2014/173995A1
The invention provides a process to separate levulinic acid from a biomass hydrolysate said process comprising extraction using as an organic solvent a substituted benzene comprising (i) at least one OR1 group wherein R1 is H or CH3; and...  
WO/2014/173973A1
The invention provides a process for the preparation of monoethylene glycol from sucrose comprising the steps of: i) hydrolysing sucrose to form a reaction product stream comprising glucose and fructose; ii) separating the reaction produ...  
WO/2014/167509A3
Discloses novel crystalline forms of 2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic acid (Formula II) and its sodium derivatives (Formula I) and the process for preparation thereof.  
WO/2014/166273A1
The present invention relates to a β−hydroxy−β−methylbutyric acid purification method, comprising: enabling the crude β−hydroxy−β−methylbutyric acid and alkali to undergo neutralization reaction, to obtain β−hydroxy−...  
WO/2014/169214A1
This invention provides processes to convert biomass, including wood and agricultural residues, to levulinic acid and co-products. Some variations treat feedstock with steam and/or hot water to produce an extract liquor containing hemice...  
WO/2014/155291A1
The invention provides processes for the manufacture of a compound of formula (IA ). The invention further provides improved methods for the conversion of the compound of formula (I A ) into pregabalin.  
WO/2014/159802A1
The present invention provides compounds of Formula (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulator...  
WO/2014/159050A1
There is provided individual polymorphic forms of treprostinil and pharmaceutical formulations comprising the same, methods of making and using the same. The polymeric forms include crystalline treprostinil monohydrate Form A, crystallin...  
WO/2014/157607A1
Provided is a method for improving the optical purity of optically active 2-hydroxycarboxylic acids that are useful as raw materials in the manufacture of drugs, agricultural chemicals, and industrial products. A method for improving the...  
WO/2014/159992A1
The invention describes processes to prepare levulinic acid, formic acid and/or hydroxymethyl furfural from various biomass materials.  
WO/2014/159794A3
The present invention provides compounds of Formula (I): (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modu...  
WO/2014/157315A1
Provided is a method capable of obtaining, from glycerin, desired lactic acid having a high yield of 30% or greater, which is similar to conventional methods, under reaction conditions at lower temperature and lower pressure than convent...  
WO/2014/153203A2
In one aspect, the invention provides compounds of Formula I, and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the su...  
WO/2014/150387A1
A crude composition comprising a ketocarboxylic acid such as levulinic acid, derived from biomass in an aqueous phase comprising impurities, can be efficiently converted in high yield to the corresponding dicarboxylic acid, such as succi...  
WO/2014/138907A1
The present invention relates to substituted aromatic compounds for use in prevention or treatment of various fibrotic diseases and conditions in subjects, including pulmonary fibrosis, liver fibrosis, skin fibrosis and cardiac fibrosis,...  
WO/2014/138906A1
The present invention relates to compounds of: or a pharmaceutically acceptable salt thereof, wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(0)-(CH2)n-CH3 or CH(OH)-(CH2)n-CH3 wherein n is 3 or 4; R1 is H, F or OH; R2 is C5 a...  
WO/2014/141169A3
Novel compounds isolated or derived from Alpiniae Oxyphyllae Fructus, chemically synthesized novel compounds, methods of preparing the novel compounds and uses thereof as neuroprotectants or drugs for treating neurodegenerative diseases ...  
WO/2014/136692A1
Provided is a method that is for recovering an anionic fluorine-containing emulsifier and that can easily and efficiently recover the anionic fluorine-containing emulsifier adsorbed by a basic ion exchange resin. An organic solvent havin...  
WO/2014/132135A3
A method of preparing 2-((5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenyloxy)butan oic acid is provided.  
WO/2014/129384A1
Provided are an intestinal tract-protecting agent and an agent for preventing or ameliorating a disease caused by an injury in the barrier function of the intestinal tract, which comprise a hydroxylated fatty acid, in particular a hydrox...  
WO/2014/129612A1
The present invention provides a process for producing a compound of the formula (1) wherein X represents a hydrogen atom, etc., and Y represents a hydrogen atom, etc., which comprises step 1 of reacting a compound of the formula (2) and...  
WO/2014/118448A1
The invention relates to a method for purifying a glycolic acid obtained by fermentation, as a result of a heat treatment aiming to eliminate the glucose and the residual sugars from the fermenting carbon source. Such a treatment leads t...  
WO/2014/114824A1
The invention relates to a method for the production of a multi-metal sulfur-containing supported catalyst, characterised in that it includes steps comprising the impregnation of the different metals and a complexing agent, and subsequen...  
WO/2014/111980A1
The present invention provides: a Janus-type triptycene derivative which is represented by general formula [I] and is useful as a material for a self-assembled monomolecular film; a Janus-type triptycene derivative which is represented b...  
WO/2014/111446A1
The invention relates to a process for the production of 5-formylvaleric acid and adipic acid or esters thereof from an isomeric mixture of pentenoic acid or esters thereof said mixture comprising at least 4-pentenoic acid or esters ther...  
WO/2014/108415A1
The invention relates to a process for producing acrylic acid, comprising: converting a C3-oxygenate into a C3-hydroxyacid, wherein said C3-oxygenate is selected from the group consisting of 1-propanol, 2-propanol, propanal, acetone, mon...  
WO/2014/106194A1
The invention provides new crystalline forms of 7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopen tyl]-hept-5-enoic acid. This compound is commonly referred to as "bimatoprost acid." The novel crystalline forms are designated ...  
WO/2014/105289A1
In some variations, the invention provides a process for producing furfural, 5- hydroxymethylfurfural, and/or levulinic acid from cellulosic biomass, comprising: fractionating the feedstock in the presence of a solvent for lignin, sulfur...  
WO/2014/101690A1
The present invention relates to the field of pharmaceutical synthesis, and specifically, to a method for preparing an Ezetimibe chiral intermediate. The method is as follows: a method for preparing a compound with a formula (b) structur...  
WO/2014/097040A1
Process for preparing lactic acid, comprising a step of glycerol conversion in the presence of a heterogeneous catalyst based on platinum on zirconium, in a basic medium under an inert atmosphere.  
WO/2014/095080A9
Process for the purification of carboxylic acid having a chain length from one to five carbon atoms comprising the steps of transforming the carbocylic acid to its monoester and/or its diester, and processing the mono- and/or the diester...  
WO/2014/095080A3
Process for the purification of carboxylic acid having a chain length from one to five carbon atoms comprising the steps of transforming the carbocylic acid to its monoester and/or its diester, and processing the mono- and/or the diester...  
WO/2014/096870A1
A process for producing lactic acid and barium hydroxide from barium lactate is provided. The process comprises (a) reacting barium lactate with an acid selected from the group consisting of hydrochloric acid and nitric acid, to produce ...  
WO/2014/094511A1
The present invention relates to the preparation of intermediates of treprostinil, a preparation method for same, and the preparation of treprostinil thereby. Specifically, the invention relates to the compound of formula (VI), the prepa...  
WO/2014/087016A1
The invention provides a process for the production of a biomass hydrolysate suitable for the production of levulinic acid and formic acid, a biomass hydrolysate obtainable by said process, a process for the production of levulinic acid ...  
WO/2014/087015A1
The invention provides a process for the isolation of levulinic acid and formic acid from a composition comprising formic acid and levulinic acid, said process comprising a solid-liquid separation step, a vapor removal step, and a solven...  
WO/2014/087646A1
The invention pertains to an onium salt, a liquid composition containing said onium salt and cellulose, and a cellulose recovery method. The invention makes it possible to provide an onium salt having an extremely high ability to dissolv...  
WO/2014/083186A3
There is provided a compound comprising the general structure (I) in which, X is N or O; R3 is OR4 or R4; wherein when X is N, R1 is H, R5 or OR6; R2 is OC(O)R7; and R4 is R5, OR5 or aryl, which is unsubstituted or substituted with at le...  
WO/2014/083186A2
There is provided a compound comprising the general structure (I) in which, X is N or O; R3 is OR4 or R4; wherein when X is N, R1 is H, R5 or OR6; R2 is OC(O)R7; and R4 is R5, OR5 or aryl, which is unsubstituted or substituted with at le...  
WO/2014/081951A1
Methods, processes and systems for using solid catalysts to simultaneously produce lactic acid and propylene glycol from glycerol are provide, as are methods, processes and systems of converting glycerol use heterogeneous catalytic agent...  
WO/2014/078175A1
A compound of formula (I) wherein Rf is -CF3, -C2F5, -CF2CFXCF3; X is -F, or -GC3F7; Y is -H, -CI, or -Br; R is -0-C(0)-R1, -(CH2)nO-C(0)-R1, -(OCH2CH2)mOC(O)-R1; -(CH2)n(OCH2CH2)MO-R1; n is 1 to 10; m is 1 to 10; R1 is -C(R3)=CH2; R3 is...  
WO/2014/078014A3
Gamma-butyrolactone ("GBL") and Gamma-hydroxybutyrate ("GHB") having a unique carbon footprint as defined by the percent modern carbon (pmc) are described herein. The percent modern carbon can be controlled by varying the amounts of biob...  
WO/2014/060640A8
The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-l,2-diphenyl-but-l-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.  
WO/2014/060640A1
The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-l,2-diphenyl-but-l-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.  
WO/2014/056005A1
The invention relates to a method for producing lactic acid from glycerol, a catalyst selected from the group consisting of ruthenium, palladium and cobalt and/or mixtures thereof being used and the method being carried out in an aqueous...  
WO/2014/040528A1
Provided are two polymorphs of a compound (Z)-N-[2-(diethylin) ethyl]-2-methyl-7-(1, 2-dihydro-5-fluorine-2-oxo-3H-indol-3-ylidene) 4, 5, 6, 7-terahydro-1H-indol-3-carboxylamide L-malate as represented by formula (I), preparation method ...  
WO/2014/043182A3
Processes process for producing adipate or adipic acid using biological pathways and chemical catalyzes are disclosed. Homocitric acid may be a substrate in reaction pathways leading to adipic acid or a salt thereof.  

Matches 101 - 150 out of 9,875