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WO/2012/059933 |
The present invention relates to an improved and commercially, viable process for the resolution of racemic cis milnacipran of formula I and its pharmaceutically acceptable salts of formula II. The present invention comprises using racem...
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WO/2012/060387 |
Novel compounds represented by formula (I) are useful for preventing or treating diseases caused by protozoans. Use is made of one or more members selected from among compounds represented by formula (I), optical isomers thereof and phar...
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WO/2012/055014 |
Phenylketone carboxylate compounds of Formula I, wherein n=2-6; R=C(0); -OC(O)- or -CH( OH)-; A is (CH2)mCOOH, W(CH2)mCOOH or YCH(COOH)((CH2)pCH3) when B is Ft B is (CH2)mCOOH, W(CH2)mCOOH or YCH(COOH)((CH2)pCH3) when A is Ft or A snd B ...
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WO/2012/056318 |
The present invention deals with a method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway comprising the transformation of malate in 4-phospho-malate using a malate kinase, said 4- phospho-malate being transformed...
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WO/2012/051774 |
Disclosed is a process for salting out and extracting organic acid from a fermentation broth, which is characterized by adding a dissoluble inorganic or organic salt and an extractant into the organic acid fermentation broth, stirring fo...
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WO/2012/053232 |
The anti-Leishmania compound represented by formula (3).
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WO/2012/054314 |
Waterborne coating compositions are disclosed that include a latex emulsion polymer, and, as a coalescent, a levulinic acid ester of a monohydric aliphatic alcohol having from 10 to 20 carbon atoms. The coating compositions of the invent...
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WO/2012/052703 |
A process for the production of a complex of lactic acid and either ammonia or an amine, comprising reacting one or more saccharides with barium hydroxide to produce a first reaction mixture comprising barium lactate, and contacting at l...
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WO/2012/046787 |
The purpose of the present invention is to provide a diene-based carboxylate anion, and salt thereof, which has a specific structure and is a previously unstudied novel compound, and furthermore to provide a diene-based carboxylate anion...
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WO/2012/047251 |
Low molecular weight gelators, methods of making such gelators, organogels comprising such gelators and systems and methods of using such gelators for the containment and/or remediation of a release and/or spill of a crude oil, a petrole...
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WO/2012/042534 |
The present invention relates to the synthesis of R-sitagliptin. The present invention also relates to a compound of formula (IV) or its salt, that are useful as key intermediate in the synthesis of R-sitagliptin or pharmaceutically acce...
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WO/2012/040007 |
Disclosed is a process for the extractive recovery of an acid catalyst from an aqueous mixture of glycolic acid with an extraction solvent comprising a tertiary amine or an onium carboxylate compound, a modifier, and a diluent. The acid ...
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WO/2012/033359 |
Disclosed is a method of preparing alkyl butyrate, which comprises: (a) producing a fermented liquid containing butyrate salt through a fermentation process using butyric acid-producing strains; (b) obtaining an extracted liquid containi...
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WO/2012/033225 |
The present invention relates to a novel method for producing a pyridazinone compound and an intermediate thereof as shown in the following scheme: wherein the symbols are as defined in the specification.
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WO/2012/031356 |
This present invention relates to an organosolv process for the extraction of materials from lignocellulosic biomass. This invention further relates to the chemicals and their derivatives extracted from biomass, uses, apparatus, methods,...
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WO/2012/026106 |
The present invention addresses the problem of providing an optical isomer having the stronger activity of a compound that is stronger than conventional steroids or NSAIDs. The problem was resolved by discovering that an optical isomer o...
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WO/2012/017441 |
Disclosed is a process for the preparation of S-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid (I) the key intermediate for the preparation of Ambrisentan [(+)-2(S)-(4,6-Dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diph
enylpropionic acid]. ...
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WO/2012/018418 |
A method for producing and recovering a carboxylic acid in an electrolysis cell (104). The electrolysis cell (104) is a multi-compartment electrolysis cell (104). The multi-compartment electrolysis cell (104) includes an anodic compartme...
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WO/2012/018418 |
A method for producing and recovering a carboxylic acid in an electrolysis cell (104). The electrolysis cell (104) is a multi-compartment electrolysis cell (104). The multi-compartment electrolysis cell (104) includes an anodic compartme...
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WO/2012/013755 |
The invention relates to a process for preparing 1-aryl-pyrazol-3-one intermediates, tautomers, and salts thereof, to novel intermediates, and to the use of the intermediates in the preparation of sigma receptor inhibitors.
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WO/2012/009816 |
Treprostinil is prepared by a process which involves Pauson - Khan cyclization of an an alkene-substituted, alkyne-substituted benzene corresponding to formula : (I) where PMB represents para-methoxy benzyl protecting group and R1 and R2...
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WO/2012/010413 |
The invention relates to aryloxy-alkylene substituted hydroxyphenyl hexynoic acid derivatives of formula (I) and to their physiologically compatible salts. The compounds are suitable for, for example, the treatment of diabetes, because t...
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WO/2012/010316 |
The invention relates to a salt or cocrystal of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)- phenol (component a) and at least one acid component (b1 ) or at least one acid component (b2), wherein the salt or cocrystal of component (a) a...
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WO/2012/004270 |
The invention relates to spirocyclically substituted 1,3-propane dioxide derivatives and to their physiologically compatible salts. The invention relates to compounds of formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, A and X have ...
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WO/2011/161255 |
The present invention provides an alternative synthesis of N-substituted aminotetralines comprising resolution of N-substituted aminotetralins of formula (II), wherein R1, R2 and R3 are as defined for compound of formula (I).
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WO/2011/162404 |
The present invention relates to a process for producing an α-ketocarboxylic acid, comprising a step of oxidizing an α-ketoaldehyde by mixing a base, carbon dioxide, the α-ketoaldehyde and a compound represented by formula (2-1).
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WO/2011/159740 |
The present invention generally relates to synthetic methods for preparing tetranor-prostaglandin D, J, E, A, and F metabolites.
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WO/2011/159740 |
The present invention generally relates to synthetic methods for preparing tetranor-prostaglandin D, J, E, A, and F metabolites.
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WO/2011/151080 |
The present invention relates to oral pharmaceutical compositions comprising co-crystals of tramadol and celecoxib, processes for preparation of the same and their use as medicaments, more particularly for the treatment of pain.
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WO/2011/150636 |
Disclosure is a method for preparing disodium stannous citrate, comprising the following steps: selecting trisodium citrate and stannous chloride as starting materials and respectively dissolving trisodium citrate and stannous chloride i...
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WO/2011/148661 |
Provided is a dispersion composition wherein nano-sized zirconium oxide particles are excellently dispersed by the addition of a small amount of a dispersant. The dispersion composition can be obtained by dispersing zirconium oxide parti...
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WO/2011/148660 |
Provided is a dispersant for non-aqueous dispersion media that can be used for a broad range of substances to be dispersed and which can exhibit excellent dispersion stability with small amounts added. The dispersant for non-aqueous disp...
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WO/2011/148521 |
Provided is a dispersion composition that exhibits excellent dispersion with the addition of a small amount of dispersant to nano-sized zirconium oxide particles. The dispersion composition is obtained by dispersing zirconium oxide parti...
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WO/2011/148520 |
Provided is a dispersant for non-aqueous dispersion media that can be used for a broad range of substances to be dispersed and which can exhibit excellent dispersion stability with small amounts added. The dispersant for non-aqueous disp...
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WO/2011/143690 |
A process for the preparation of solid amine salts of aromatic substituted carboxylic acid herbicides by reaction of the aromatic substituted carboxylic acid herbicide with an amine comprising reacting the aromatic substituted carboxylic...
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WO/2011/144792 |
The invention relates to a novel method for the synthesis of polyaleurate polyester and to the use of same as a biodegradable packaging material for food or active substances.
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WO/2011/125882 |
Disclosed is an alternative method for efficiently producing lactic acids from starting materials containing carbohydrates such as cellulose. Specifically disclosed is a method for producing lactic acid and/or a lactic acid ester by heat...
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WO/2011/119128 |
The invention relates to the field of nanotechnologies and chemistry, and more precisely to metal carboxylates, which are widely used in perfumery, the food industry, medicine, agriculture and biology, as well as in the field of industri...
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WO/2011/116686 |
Sitagliptin intermediate compounds of formula (f), preparation methods and uses thereof are provided. The compounds of formula (f) are prepared by the following steps: compounds of formula (a) are subjected to electrophilic reaction with...
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WO/2011/111841 |
The genes of a novel lipoxygenase and a novel allene oxide synthase derived from Lemna paucicostata strain SH are identified, and a plant growth regulator (KODA) is produced with high yield by using a Lemna paucicostata strain that expre...
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WO/2011/101287 |
The invention relates to a method for producing ether carboxylates.
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WO/2011/101336 |
The invention relates to a method for producing ether carboxylates.
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WO/2011/097797 |
Disclosed are a kind of polyphenol acrylic acid derivative, its preparation, and use in preparing medicine. The compound can be used as an inhibitor of protein kinase or cytokine, tranquilizer, and also can be used to treat eczema, psori...
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WO/2011/098683 |
The invention relates to a method for processing a lignocellulose or cellulose biomass using heterogeneous tungsten-based catalysts dispersed on a support based on (an) oxide(s), preferably (an) aluminium and/or zirconium and/or titanium...
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WO/2011/098985 |
The invention relates to compounds of formula (Formula III) (III) and of formula (Formula (IV) (IV), to methods for producing said compounds, and to the use thereof in the synthesis of saxagliptin.
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WO/2011/100608 |
The patent application relates to a method of producing a monomer component from a genetically modified polyhydroxyalkanoate (PHA) biomass, wherein the biomass is heated in the presence of a catalyst to release a monomer component from t...
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WO/2011/095631 |
The present invention discloses a process for the preparation of lactic acid comprising the steps of: a) providing an aqueous medium comprising magnesium lactate; b) adding to the aqueous medium comprising magnesium lactate a monovalent ...
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WO/2011/087600 |
A process for the conversion of an alcohol to an olefin is disclosed. The process may include: contacting at least one C2 to C 5 alcohol with an organic acid in the presence of an esterification catalyst to convert at least a portion of ...
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WO/2011/086933 |
Disclosed are a bicyclohexane derivative, which is useful in technical fields associated with photoresists or intermediates for pharmaceutical and agricultural compounds, and a method for producing the same. Specifically disclosed is a b...
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WO/2011/084771 |
New triaminophenol compositions and related compounds are disclosed, as are processes for their preparation and for the preparation of novel salts and diacid complexes from such compounds. Polymers prepared from these compositions can be...
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