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JPH11507022A |
Disclosed are a novel class of antiandrogenic compounds including saturated and unsaturated fatty acids, catechin gallates, their derivatives, and synthetic analogs, their method of synthesis, and their use in treating disorders associat...
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JP2889056B2 |
Compounds of formula I, and pharmaceutically acceptable salts thereof, useful in the treatment of neuropsychiatric disorders such as psychoses; pharmaceutical compositions comprising a compound of formula I and a pharmaceutically accepta...
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JP2889702B2 |
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JPH11106360A |
To obtain the subject new compound useful as a raw material for electroconductive polymers, photographic photo-sensitive materials, fluorescent materials, transparent resin coatings for organic glasses, optical materials for optical fibe...
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JP2873090B2 |
Novel compounds of Formula (I) are described herein. These compounds inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production. The compounds of the presen...
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JP2867257B2 |
The invention provides a process for the preparation of fungicidally active cyclopentene derivatives of the general formula cyclopentane derivatives of the general formula and cyclohexane derivatives of the general formula in which n, R,...
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JP2856116B2 |
The present invention provides a vinylmonomer represented with the following general formula (I): om or a methyl group, R2 represents a dihydric, bridged cyclic hydrocarbon group having a carbon number in the range of 7 to 13 both inclus...
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JPH1121271A |
To obtain the subject new compound wherein the number of carbon atoms is increased so as to raise the glass-transition temperature of polyester. This compound is shown by the formula (R<1> and R<2> are each an 1-10C alkyl; R<3> is H or a...
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JPH111453A |
To easily obtain the optically active isomer of the subject compound useful as an intermediate for medicines, agricultural chemicals, etc., in an excellent yield and in a good optical purity by optically resolving cis-2- fluorocyclopropa...
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JP2840899B2 |
Ethyl (1R,6S)-2,2,6-trimethylcyclohexanecarboxylate represented by formula (1) (* CHEMICAL STRUCTURE *) (1) is disclosed. Also, an aroma chemical composition containing the same and a process of the production of the same are disclosed.
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JPH10330347A |
To obtain the subject compound capable of being widely used for fluorescent whitening of materials to be dyed such as a knit or woven fabric, especially made of cotton and polyamide or for the fluorescent whitening of paper by deaminatin...
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JPH10324659A |
To obtain the subject compound useful as an intermediate for agricultural and horticultural chemicals and medicines by an alkali saponification of a 1-4C alkyl ester corresponding to the subject compound in alkalinity under a specific co...
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JPH10316612A |
To produce the subject compound in high selectivity and yield by oxidizing a specific aldehyde in an organic solvent in the presence of a catalyst with oxygen or an oxygen-containing gas in no need of large amounts of chromium compound, ...
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JP2825534B2 |
New fluorocyclopropyl derivatives of the formula …… in which… R stands for alkyl, optionally substituted aryl or optionally substituted aralkyl,… X stands for hydrogen, chlorine or bromine and… R<1> stands for hydroxyl, alkoxy,...
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JPH10511387A |
This invention relates to certain 1,3,3-(trisubstituted)cyclohexane dimers and related compounds which are useful in treating allergic and inflammatory diseases and for inhibiting the production of Tumor Necrosis Factor (TNF).
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JP2809620B2 |
To provide the subject new compound useful as an inert fluid. This compound is expressed by the formula I (Z is COOCH3, COOC2H5 or COOC2H4OCH3), e.g. dimethyl 1,3-perfluorocyclohexanedicarboxylate of the formula II. The objective compoun...
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JPH10510656A |
Compounds, methods and compositions are provided for inducing natriuresis in a mammal. Methods for isolating and synthesizing the natriuretic compounds are also provided. Therapeutic methods using the natriuretic compounds are also provi...
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JP2807792B2 |
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JP2808322B2 |
The invention provides a process for the preparation of fungicidally active cyclopentene derivatives of the general formula cyclopentane derivatives of the general formula and cyclohexane derivatives of the general formula in which n, R,...
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JPH10509959A |
The object of the present invention is to provide asiatic acid derivatives, its pharmaceutically acceptable salts or esters. Asiatic acid, its trisaccharide asiaticoside and mddecassic acid, extracted from Centella asiatica have been use...
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JPH10245360A |
To provide a production process for carbonyl compound that can recover the noble metal complex as a rhodium complex in no need of precipitation of the complex, after the reaction mixture tentatively is taken out from the reactor in order...
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JPH10509146A |
Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The presently claimed compounds have the generalized formula in which each ...
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JP2788657B2 |
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JPH10218836A |
To produce malonic acid and an alkylmalonic acid in high yields without generating salts by bringing an aqueous mixture of an ester into contact with a specific acidic ion-exchanger, distilling away the alcohol produced at the time, remo...
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JP2780381B2 |
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JP2776787B2 |
Novel nonatetraenoic acid derivatives of the formula wherein the dotted bond is optional and R1 and R2 are as defined in the specific ation selectively bind to retinoic acid X-receptors (RXR) have anti-acne acitvity and potentiate the ac...
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JPH10507166A |
The present invention provides a process for the preparation of cyclopropanecarboxamide which comprises the steps of: (1) contacting cyclopropanecarboxylic acid with ammonia in a reactor at a temperature of 200 to 260 DEG C and a pressur...
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JPH10506383A |
Compounds, methods and compositions are provided for inducing natriuresis in a mammal. Methods for isolating and synthesizing the natriuretic compounds are also provided. Therapeutic methods using the natriuretic compounds are also provi...
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JPH10152453A |
To produce a new bicyclo[3.2.1]octane derivative used by oral administration, having effective squalene synthase inhibiting activities and useful for treatment of cholesterinemia, etc., by substituting C atom for O atom of a specific oct...
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JPH10505610A |
An improved process for the preparation of R(+)1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenyl-3-cyclohexen-1-
yl)methyl]pyridine by a novel synthesis is described where 5-oxo-3-phenyl-3-cyclohexene-carboxylic acid is converted in five operatio...
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JP2734725B2 |
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JP2730776B2 |
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JPH1072402A |
To provide a method for selectively and efficiently producing a fluorocycolopropane derivative suitable as a production intermediate for a compound useful for production of a medicine, etc., by directly introducing fluorine atom to the c...
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JP2721553B2 |
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JP2720934B2 |
A novel two-step process for preparing 3-(2-chloro- 2-(4-chlorophenyl)vinyl)-2,2-dimethylcyclopropanecarboxylic acid, starting from 3-chloro-3-(4-chlorophenyl)propenal and chloromethyl isopropyl ketone.
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JPH1059801A |
To provide a novel compound which is useful as a cut-flower freshness- preserving agent. This novel compound is represented by formula I (R1 is a 1-8C alkyl, phenyl, phenethyl, styryl), typically 1-benzoylaminomethyl- cyclopropanecarboxy...
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JP2717787B2 |
Compounds of formula (I): in which X1 and X2 = Hal, R1 = alkyl, aryl, perfluoroalkyl, C IDENTICAL N, and R=H, alkyl or the residue of an alcohol employed in the synthesis of the pyrethrinoid esters.
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JPH10501549A |
PCT No. PCT/KR95/00074 Sec. 371 Date Dec. 6, 1996 Sec. 102(e) Date Dec. 6, 1996 PCT Filed Jun. 7, 1995 PCT Pub. No. WO95/34300 PCT Pub. Date Dec. 21, 1995Process for the preparation of (-)-pimara-9(11),15-diene-19-oic acid(acanthoic acid...
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JP2710097B2 |
PURPOSE: To produce a compound useful for exterminating parasites, nematodes and mites by reacting cyclopropanecarboxylic acids with a reducing agent. CONSTITUTION: A compound represented by formula I (X1 and X2 are each a halogen; R1 is...
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JP2708118B2 |
Di- and tri-substituted perfluorocycloalkane compounds which have a cyclohexane or decahydronaphthalene nucleus are provided. These perfluorocycloalkane compounds are carbonyl fluorides and derivatives thereof.
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JP2705792B2 |
Bicyclic aromatic compound having the formula (R) wherein R1, R2, R3 and R4 represent hydrogen or alkyl, at least two of R1-R4 radicals being other than hydrogen, A represents methylene or dimethylene; when A represents dimethylene, R1 a...
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JPH09328450A |
To obtain the subject compound suitable as an acid useful for producing an active ingredient for a pyrethroid-based insecticide by using (-)-1R,3R,4R- p-menethane-3,8-diol as a reagent for optical resolution. (1RS)-trans-3-(2,2-Dichlorov...
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JPH09512246A |
Vanadium-containing Beta zeolite, and its use as catalyst in organic reactions.
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JP2676925B2 |
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JP2677931B2 |
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JPH09291062A |
To obtain a new compound capable of affording resin cured products excellent in resistance to moisture absorption, water repellency and flame retardancy, and useful as a curing agent for such cured products. This new compound is a perflu...
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JP2667294B2 |
Indane and indene derivs. of formula (I) and their salts are new. In (I), R1 = X(CH2)nAr, X(CH2)nR8 or a gp. (a); R2 = H, Ar or (a); P1 = X(CH2)nR8; P2 = X(CH2)nR8 or XR9Y; R3, R5 = R11, H, OH, 1-8 alkoxy, S(O)qR11, N(R6)2, Br, F, I, Cl,...
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JP2666457B2 |
NEW MATERIAL:An alicyclic tetracarboxylic acid expressed by formula I or II (R<1> to R<4> may be same or different and H or hydrocarbon group) and derivatives thereof. USE:Useful in wide fields of a raw material for polyimides, water-sol...
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JPH09249613A |
To obtain an alicyclic dicarboxylic acid diester having a new norbornane skeleton, useful as an intermediate raw material for polyester resins, etc., used for base, etc., of photographic film and having a new norbornane skeleton by using...
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JP2654151B2 |
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