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Matches 101 - 150 out of 2,195

Document Document Title
WO/2010/009068A2
The present application describes modulators of MCP-1 or CCR-2 of formula,(I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R1, R2, R4 and R6, are defined herein. In addition, methods o...  
WO/2010/005003A1
Disclosed is a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid with a high yield and high selectivity. Specifically disclosed is a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid, where...  
WO/2009/146659A1
Disclosed is a process for preparing isopimaric acid, comprising the following steps: first step: dissolving thermally isomerized rosin in acetone, adding in drops a solution of isobutanolamine in acetone to form precipitate, standing, f...  
WO/2009/121788A1
A process for the preparation of a compound of formula (Ia): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds.  
WO/2009/112622A1
The present invention describes a method for producing mero sesquiterpenes, more specifically drimenylbenzenes and drimenylnaphtho­quinones, by means of a Diels-Alder reaction between a labdane diterpene and a dienophyl. Subsequently, a...  
WO/2009/089365A3
A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammat...  
WO/2009/089365A2
A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammat...  
WO/2009/077590A1
The present invention relates to a method for producing 2,2-dichlorocyclopropane carboxylic acid esters, wherein an α,β-unsaturated carboxylic acid ester is reacted with chloroform in the presence of an aqueous alkali metal hydroxide s...  
WO/2009/015504A3
Disclosed are substituted mono- or bicyclic carboxy acids that block off-notes in consumables and methods of blocking off-notes in consumables including off -notes provided by sweeteners such as stevioside, swingle extract, glycerhizin, ...  
WO/2006/078813A3
The present invention relates to novel arginine analogs, and methods for their synthesis and use. Such analogs are designed to provide a protected or free thiol (- SH) group, thereby providing a convenient linkage chemistry for coupling ...  
WO/2008/149370A3
A general method is disclosed for the conversion of aldehydes and alkenes to the corresponding carboxylic acids and 1,2-diols. The method is carried out in a catalyst-free aqueous medium under an atmosphere of oxygen or oxygen containing...  
WO/2008/132128A3
Process for the manufacture of UK- 427,857 ( Maraviroc ) which comprises a step wherein enantiopure (S)-3-amino-3-phenylpropan-1-ol is manufactured from a mixture of its enantiomers by crystallizing or precipitating from a solution conta...  
WO/2009/015504A2
Disclosed are substituted mono- or bicyclic carboxy acids that block off-notes in consumables and methods of blocking off-notes in consumables including off -notes provided by sweeteners such as stevioside, swingle extract, glycerhizin, ...  
WO/2008/149370A2
A general method is disclosed for the conversion of aldehydes and alkenes to the corresponding carboxylic acids and 1,2-diols. The method is carried out in a catalyst-free aqueous medium under an atmosphere of oxygen or oxygen containing...  
WO/2008/148468A1
The present invention relates to di(hetero)arylcyclohexane derivatives of the formula (I), in which Ar1, Ar2, R1 and R2 have the meanings indicated in the claims. The compounds of the formula (I) are valuable pharmaceutical active compou...  
WO/2008/024892A3
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-Beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11...  
WO/2007/124435A3
Provided are compositions and methods for intracellular detection of enzyme activity. One example of a composition is a histone deacetylase substrate comprising a compound of the following formula (I): One example of a method is a method...  
WO/2007/127440A3
The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invent...  
WO/2008/103319A3
Compounds and methods for use in detecting gabapentin in a sample suspected of containing gabapentin are disclosed. Gabapentin derivatives are used to produce gabapentin conjugates. A gabapentin-immunogenic carrier conjugate may be used ...  
WO/2008/132720A1
It is in the scope of the invention to disclose a biocidic textiles and fabrics, comprising at least one insoluble proton sink or source (PSS). The textiles and fabrics is provided useful for killing living target cells (LTCs), or otherw...  
WO/2008/132128A2
Process for the manufacture of UK- 427,857 ( Maraviroc ) which comprises a step wherein enantiopure (S)-3-amino-3-phenylpropan-1-ol is manufactured from a mixture of its enantiomers by crystallizing or precipitating from a solution conta...  
WO/2008/092955A1
The present invention relates to synthesis procedures and intermediates of a compound offormula: (XVII) and the salts thereof.  
WO/2008/074677A1
The present invention relates to a process for the preparation of 1 -(2-cthyl-butyl)-cyclohexanecarboxylic acid which is useful as an intermediate in the preparation of, pharmaceutical active compounds, comprising reacting cyclohexanecar...  
WO/2008/064432A1
This invention relates to compounds of Formula (I), wherein A is a carboaromatic or heteroaromatic ring having one or more substituents; R6 Formula (A) is optionally substituted with one or more substituents; and n is 0, 1 or an integer ...  
WO/2008/008837A3
Novel methods of increasing the biosynthesis of aromatic amino acids and compositions containing the precursors of said aromatic amino acids or nicotinamide and methods of use thereof. In addition, methods of monitoring the therapeutic e...  
WO/2008/027570A2
The present invention provides a method of isolating shikimic acid from a plant. First, a plant is provided. Next, the plant is grown in the absence of glyphosate for a first time period. The plant is then treated with glyphosate for a s...  
WO/2008/024892A2
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-Beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11...  
WO/2008/008837A2
Novel methods of increasing the biosynthesis of aromatic amino acids and compositions containing the precursors of said aromatic amino acids or nicotinamide and methods of use thereof. In addition, methods of monitoring the therapeutic e...  
WO/2007/064663A3
A method of producing gabapentin (l-amino-methyl)-l-cyclohexaneacetic acid) from its hydrochloric or hydrobromic salt or mixtures thereof in an anhydrous medium, the method consisting of: - dissolving gabapentin hydrochloride or hydrobro...  
WO/2007/136573A2
Tricyclic compounds containing a cyclopropyl carboxylic acid or carboxylic acid derivative (e.g. amide) fused to a bicyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled recepto...  
WO/2007/073856A3
The invention relates to novel compounds of formula (I), wherein W, X, Y, Z, A, B, D, Q1, Q2, and G have the meanings indicated in the description, several methods and intermediate products for the production thereof, the use thereof as ...  
WO/2007/103571A3
A blend of two different compounds may be applied together to form a nucleating agent additive composition. This additive composition is useful as an additive in thermoplastics, polyolefins and/or polymer resins. A blend of of a bicyclo[...  
WO/2007/119580A1
Disclosed is a process for production of a carboxylic acid chloride compound represented by the general formula (III), which comprises reacting a carboxylic acid compound represented by the general formula (I) with an acid chlorinating a...  
WO/2007/103571A2
A blend of two different compounds may be applied together to form a nucleating agent additive composition. This additive composition is useful as an additive in thermoplastics, polyolefins and/or polymer resins. A blend of of a bicyclo[...  
WO/2007/089781A2
Diamino polyacetate benzene compounds are used as a selective fluorescence probe, sensor, or binders for divalent metal ions. The compounds provide for uses as divalent metal ion sensors in diagnostic applications and binders for environ...  
WO/2007/073856A2
The invention relates to novel compounds of formula (I), wherein W, X, Y, Z, A, B, D, Q1, Q2, and G have the meanings indicated in the description, several methods and intermediate products for the production thereof, the use thereof as ...  
WO/2007/001940A3
The present invention provides novel amino acid compounds useful in detecting and evaluating brain and body tumors. These compounds have the advantageous properties of rapid uptake and prolonged retention in tumors and can be labeled wit...  
WO/2007/063974A1
Disclosed is a process for hydrogenating an aromatic ring of an aromatic ring compound which proceeds under comparatively mild conditions. This process for hydrogenating an aromatic ring of an aromatic ring compound can be carried out in...  
WO/2007/058156A1
Disclosed is a novel tetracarboxylic acid compound having excellent characteristics such as high transparency, low dielectric property, low water absorption, low thermal expansion, solvent solubility and etching characteristics, while ex...  
WO/2006/134424A3
Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with water pretreated by a base are provided. The resultant carbon-isotope labeled acids are useful as radiopharm...  
WO/2007/022263A1
The present invention relates to compounds useful for detecting the activity of human MCAD, compounds useful for competitively inhibiting human MCAD, as well as methods of manufacture thereof .  
WO/2007/002128A2
The invention relates to compositions and processes for producing novel hop acid formulations having improved bioavailability, and the use of such compositions as anti-inflammatory agents, dietary supplements, and pharmaceuticals.  
WO/2007/001940A2
The present invention provides novel amino acid compounds useful in detecting and evaluating brain and body tumors. These compounds have the advantageous properties of rapid uptake and prolonged retention in tumors and can be labeled wit...  
WO/2007/001958A2
The radiolabeled non-natural amino acid 1-amino-3- cyclobutane-1-carboxylic acid (ACBC) and its analogs are candidate tumor imaging agents useful for positron emission tomography and single photon emission computed tomography due to thei...  
WO/2006/136471A1
The invention relates to a mixture of diisononyl esters of 1,2-cyclohexanedicarboxylic acid, characterized in that the isononyl radicals of the diisononyl esters contained in the mixture have a degree of branching of 1.2 to 2.0, to a met...  
WO2006087357A3
A new process is described, easy to perform on industrial scale, with high yield, for obtaining enantiomers of chrysanthemic acid starting from mixtures containing them. The process involves reacting said mixtures with enantiomers of 2- ...  
WO/2006/095355A1
The present invention relates to new salts or ion ion-pair complexes obtained by a reaction between boswellic acids or selectively enriched 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) or 11-keto-ß-boswellic acid (KBA) compounds obtained...  
WO/2006/087357A2
A new process is described, easy to perform on industrial scale, with high yield, for obtaining enantiomers of chrysanthemic acid starting from mixtures containing them. The process involves reacting said mixtures with enantiomers of 2- ...  
WO/2006/088025A1
Disclosed is a method for commercially advantageously producing a high-purity alicyclic monoolefin carboxylic acid with less impurities. Specifically disclosed is a method for producing a high-purity alicyclic monoolefin carboxylic acid ...  
WO2006065792A3
The present invention relates to non-psychoactive derivatives of tetrahydrocannabinol, which are useful in treating interstitial cystitis and relieving symptoms thereof. The invention uses cannabinol analogs, which are preferably analogs...  

Matches 101 - 150 out of 2,195