| Document |
Document Title |
|
WO/2005/123650 |
A novel fluorinated adamantane derivative. It is a compound represented by the formula AF(-COF)n, wherein AF means a fluorinated adamantane residue which is an n-valent group formed by removing n hydrogen atom(s) from adamantane (provide...
|
|
WO/2005/118564 |
One aspect of the present invention relates to methods for synthesizing milnacipran or congeners thereof Another aspect of the present invention relates to asymmetric methods for synthesizing enantiomerically enriched milnacipran or cong...
|
|
WO/2005/110963 |
The present invention relates to compounds having the general formula (I) with the definitions of RI-R3 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds as a medicament, preferab...
|
|
WO/2005/095321 |
Accordingly the present invention provides an improved and economical process for the isolation of oleanolic acid from the roots of Lantana camara, resulting in the isolation of oleanolic acid with 1% yield.
|
|
WO/2005/084141 |
The present invention relates to a composition for the prevention and the treatment of cardiovascular disease containing extracts of T. nucifera or abietane diterpenoid compound or terpenoid compound isolated from the same as an effectiv...
|
|
WO/2005/051884 |
[MEANS FOR SOLVING PROBLEMS] A novel cyclic carboxylic acid formed by the addition reaction of an unsaturated carboxylic acid with a conjugated diene compound; a metal salt of the acid; a compounding agent (A) for antifouling coating com...
|
|
WO/2005/049589 |
Disclosed are novel compounds of formula (I), having hypolipidaemic and hypocholesterolemic properties, their tautomeric forms, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acce...
|
|
WO/2005/047215 |
Processes for the preparation of certain [3.1.0] hexane derivatives which are useful as mGluR agonists, and intermediates prepared during such processes.
|
|
WO/2005/019151 |
The present invention is directed to a compound of formula I, or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator acti...
|
|
WO/2005/014519 |
The invention relates to a process for the preparation of a substituted geminal difluoroalkane, wherein an oxime is converted to the gerninal difluoroalkane using a nitrite and a complex consisting of HF and an organic base, as well as i...
|
|
WO/2005/009330 |
The invention relates to a method of obtaining inhibitors of the type II dehydroquinase enzyme and the precursors thereof from (-)-quinic acid, the aforementioned compounds having a carboxycyclohexene structure. More specifically, the in...
|
|
WO/2005/009104 |
The present invention is directed to hepatocyte nuclear factor 4a (HNF-4a) receptor modulator compounds. This invention is also directed to pharmaceutical compositions containing such compounds as well as methods of using such compounds ...
|
|
WO/2004/110973 |
The present invention discloses platinum (II) complexes with effective anticancer activity, characterized in that the new platinum (II) complexes are formed by reacting the anionic ligand of Camphoric radicals with the cationic ligand of...
|
|
WO/2004/093650 |
The present invention relates to novel modified fatty acid analogs, where a positron or gamma-emitting label is placed at a position on a fatty acid backbone and an organic substituent is substituted at the 2,3; 3,4; 4,5; 5,6 and other s...
|
|
WO/2004/091278 |
The present invention comprises an organic acid salt of gabapentin, wherein the organic acid is tartaric acid, ethanedisulfonic acid, or maleic acid. Methods for modulating the solubility and dose response of gabapentin are discussed. Me...
|
|
WO/2004/092145 |
Alpha substituted carboxylic acids of formula (I): wherein R' and R2 are as defined in the specification and R3 is A) formula (II); B) formula (III); C) formula (IV); and D) formula (V); wherein Y, Art, Are, AP, R4, R5, R6, R7, R6, R9, R...
|
|
WO/2004/085366 |
Two compounds namely ent-pimmarane 8(14), 15-diene-19 oic acid (compound 1) and ent-pimmarane 7(8), 9(11),15-diene-19 oic acid (compound 2) were isolated from Lavatera cachmeriania, these compounds, in vitro, significantly inhibited the ...
|
|
WO/2004/076349 |
Disclosed and claimed herein are e,e,e malonic acid/acetic acid tri-adduct of buckminsterfullerene of the general formula C60R3, wherein each R is independently selected from groups of the formula -CR1R2 wherein each R1 and R2 is indepen...
|
|
WO/2004/063169 |
A compound having the following formula (I): wherein R¿1? is N-containing heterocyclic ring optionally substituted with one or more suitable substituent(s), R¿2? is hydroxyamino, R¿3? is hydrogen or a suitable substituent, L¿1? is -(...
|
|
WO/2004/046079 |
The invention relates to optionally isolated and/or purified enantiomers of 2-heptylcyclopropyl-1-carboxylic acid, in addition to mixtures of two, three or all enantiomers of 2-heptylcyclopropyl-1-carboxylic acid, which are used as perfu...
|
|
WO/2004/037241 |
The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
|
|
WO/2004/037240 |
The present invention relates to the use of compounds of Formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
|
|
WO/2004/031126 |
A process for synthesis of 1-(aminomethyl)cyclohexane acetic acid hydrochloride (Gabapentin hydrochloride) comprising: a) Reaction of a mixture of acetic anhydride/ammonium acetate with 1,1-cyclohexanediacetic acid to yield 3,3-pentame...
|
|
WO/2004/009577 |
This invention is related to heteroatom containing diamondoids (i.e., 'heterodiamondoids' ) which are compounds having a diamondoid nucleus in which one or more of the diamondoid nucleus carbons has been substitutionally replaced with a ...
|
|
WO/2004/010512 |
Novel heterodiamondoids are disclosed. These heterodiamondoids are diamondoids that include heteroatoms in the diamond lattice structure. The heteroatoms may be either electron donating, such that an n-type heterodiamondoid is created, o...
|
|
WO/2004/000763 |
The invention concerns a method for preparing an unsaturated carboxylic acid from the corresponding aldehyde. More particularly, the invention aims at preparing an aliphatic carboxylic acid having at least an unsaturation conjugated with...
|
|
WO/2003/087174 |
The invention relates to defined carbocyclic and oxacarbocyclic fumaric acid oligomers. The invention also relates to the use thereof for producing a drug and to drugs comprising the inventive compounds.
|
|
WO/2003/074063 |
The invention relates to a process for producing a fraction enriched upto 100 % of 3-O-acetyl-11-keto-β-boswellic acid. An organic solvent extract of gum resin from Boswellia species is first subjected to oxidation and then acetylation ...
|
|
WO/2003/072802 |
The instant invention is a method for increasing a metazoan's lifespan, comprising administering a carboxylated derivative of a C60 fullerene. The instant invention further is a process for extending a metazoan's lifespan by administerin...
|
|
WO/2003/062185 |
The invention relates to methods for producing substituted acrylic acid esters and to the use of the latter for producing substituted $g(g)-amino acids, such as gabapentin and pregabalin. The substituted acrylic acid esters are produced ...
|
|
WO/2003/053905 |
A process for the production of 1R pyrethroid esters of formula (IIIA) or (IIIB), wherein A and B are independently chlorine or bromine or one of A or B is chlorine and the other is trifluoromethyl and R is a pyrethroid alcohol fragment,...
|
|
WO/2003/053915 |
This invention relates to compounds of the Formula (I):(Chemical formula should be inserted here as it appears on abstract in paper form)(I)or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the tre...
|
|
WO/2003/045962 |
The present invention relates to a novol class of supermolecules carboplatinum derivatives represented by general formula (I), wherein B is a polycarboxylic represented by general formula (II), wherein (R1) and (R2) and (n) is defined as...
|
|
WO/2003/040230 |
Compounds and compositions comprising specific metal salts of bicyclo[2.2.1]heptane dicarboxylate salts in order to provide highly desirable properties within polyolefin articles are provided. The inventive salts and derivatives thereof ...
|
|
WO/2003/006413 |
Novel norbornene derivatives bearing fluorinated ketone or fluorinated alcohol moieties attached directly to norbornene skeleton, which are useful as material of chemically amplified photoresists for F2 laser lithography having excellent...
|
|
WO/2002/098967 |
Compounds of and compositions comprising specific salts of saturated [2.2.2] dicarboxylate in order to provide highly desirable properties within thermoplastic (e.g., polyolefin) articles are provided. The inventive salts and derivatives...
|
|
WO/2002/094759 |
Bicyclic nucleator compounds that provide highly versatile nucleation benefits for different polyolefins are provided. Such nucleator compounds provide very high peak crystallization temperatures and significantly reduced crystallization...
|
|
WO/2002/085839 |
The compounds of the instant invention are bicyclic or tricyclic amino acids useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis...
|
|
WO/2002/079137 |
Novel compounds are disclosed that have specific chemical structures, and prodrug esters and acid-addition salts thereof, that are useful as Interleukin-1 and Tumor Necrosis Factor-a modulators, and thus are useful in the treatment of va...
|
|
WO/2002/079134 |
The present invention relates to a process for the manufacture of compounds of general formula (I), wherein R?2a¿, R?2b¿ are, independently from each other, hydrogen; halogen; lower alkoxy; cyano; -COOH; lower alkoxycarbonyl; or lower ...
|
|
WO/2002/077092 |
Compounds and compositions comprising specific metal salts of bicyclo[2.2.1]heptane dicarboxylate salts in order to provide highly desirable properties within polyolefin articles are provided. The inventive salts and derivatives thereof ...
|
|
WO/2002/066412 |
The invention relates to a method for producing cyclohexane dicarboxylic acids or derivatives thereof, e.g esters and anhydrides, wherein diene maleic acid anhydride mixtures, especially mixtures of butadiene maleic acid anhydrides or mi...
|
|
WO/2002/057201 |
Higher diamondoid derivatives capable of taking part in polymerization reactions are disclosed as are intermediates to these derivatives, polymers formed from these derivatives and methods for preparing the polymers.
|
|
WO/2002/050013 |
A carboxylic acid compound having cyclopropane ring(s) of the formula (I): wherein R is alkyl or alkenyl optionally having one or more 1,2-cyclopropylene in a carbon chain and/or optionally having cyclopropyl at the end of a chain,X is a...
|
|
WO/2002/006202 |
A process for producing compounds of formula (VIIa) and (VIIb) wherein X is a leaving group; Y and Y?1¿ are idependently Cl or Br; and Z is Cl, Br or a haloalkyl group which process comprises a) reacting a compound of formula (VII) wher...
|
|
WO/2001/096273 |
A process is provided, by which 1-substituted-cyclo-hexanecarbonyl halides of the general formula [1] can be prepared industrially practically at an extremely low cost: [1] wherein R is linear or branched C¿1-10? alkyl, C¿3-10? cycloal...
|
|
WO/2001/092200 |
The invention relates to a novel process for the preparation of certain cyclopropyl carboxylic acid esters and other cyclopropyl carboxylic acid derivatives; a novel process for the preparation of dimethylsulfoxonium methylide and dimeth...
|
|
WO/2001/064696 |
The present invention relates to dicarboxylato diammine platinum derivatives of formula (I), wherein R?1¿ and R?2¿ are defined as in the description, to method for preparing them, and to antitumor chemical compositions comprising them....
|
|
WO/2001/056959 |
A substance including the chemical structures of bicyclo[3.2.1]octan or the chemical structures of kaurene for the use in a dietary supplementation or as a constituent in a medicament for the treatment of non-insulin dependent diabetes m...
|
|
WO/2001/051455 |
Cyanohydrin homologation of the 4-cyanocyclohexanone (D) provides a 4-cyanocyclohexanoic acid (I).
|
