Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 2,165

Document Document Title
WO/2018/071320A1
The (1R,3R)- or (1S,3S)-enantiomer of 2,2-dichloro-3-(substituted phenyl)cyclopropane-carboxylic acid is prepared in a process involving chemical resolution of a racemic mixture of a trans-2,2-dichloro-3-(substituted phenyl)cyclopropanec...  
WO/2018/066447A1
A method for producing 1, 4-dicyanocyclohexane, which comprises a step for obtaining 1, 4-dicyanocyclohexane by subjecting a thermal concentrate of an ammonia aqueous solution of 1, 4-cyclohexane dicarboxylic acid to a cyanation reaction.  
WO/2018/062854A1
The present invention relates to a method for producing 1,3-cyclohexanedicarboxylic acid, wherein the efficiency and economic feasibility of a reaction can be improved by using a catalyst which exhibits excellent activity and has improve...  
WO/2018/032796A1
Disclosed is a novel 2-fluorocyclopropane carboxylic acid synthesis method, comprising the following steps: 1) reacting 1,1-dichloro-1-fluoroethane with thiophenol in the presence of alkali to produce a phenyl sulfide intermediate; 2) ca...  
WO/2018/012425A1
Provided is a method for manufacturing carboxylic acid or a salt thereof under a moderate condition and in a simple, highly-selective, high-yielding manner. Provided is a method for manufacturing a compound represented by general formula...  
WO/2018/011226A1
The invention relates to chemical compositions in the form of an organogel, comprising a gelled organic liquid, comprising or consisting of a volatile organic liquid, and at least one resin acid. The invention also relates to a method fo...  
WO/2018/010932A1
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-contai...  
WO/2017/179727A1
The present invention is a radiation sensitive resin composition which contains a polymer having a first structural unit that contains an acid-cleavable group, a first radiation sensitive acid generator and a solvent, and wherein the fir...  
WO/2017/172957A1
Compounds of Formula (I) are estrogen receptor alpha modulators, where the variables in Formula (I) are described in the disclosure. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for tr...  
WO/2017/154947A1
In order to provide a high-purity 1,4-cyclohexanedicarboxylic acid powder having excellent powder flow properties, the present invention provides a high-purity 1,4-cyclohexanedicarboxylic acid powder in which: the grain size distribution...  
WO/2017/143946A1
Provided are a fatty acid compound, a preparation method therefor and use thereof. The fatty acid compound is of a structure represented by general formula I. The compound has an AMPK activating activity and a capability of inhibiting gl...  
WO/2017/136976A1
The present invention discloses an ionic liquid having a methanofullerene carboxylate as an anion, and a preparation method thereof. The ionic liquid is comprised of the methanofullerene carboxylate anion and a quaternary ammonium cation...  
WO/2017/130871A1
The present invention provides a method for producing an acid halide solution that is useful when producing a polymerizable liquid crystal compound. This method for producing an acid halide solution includes: a first step of obtaining a ...  
WO/2017/129991A3
There is provided herein a process for the preparation of a compound of formula I (I) or a salt thereof, wherein X1 to X4, Y1 to Y4, Z and n each have meanings provided in the description. There is also provided certain compounds of form...  
WO/2017/056501A1
The present invention provides a method for producing an acid halide solution, which is useful as a production intermediate or the like that enables a polymerizable liquid crystal compound to be produced in an industrially advantageous m...  
WO/2017/035271A1
The invention provides compounds having the general formula (I): (I) and pharmaceutically acceptable salts thereof, wherein the variables RAA, n, ring A, X1, L, m, X2, R2, R3, R4, R5, X, and R6 have the meaning as described herein, and c...  
WO/2017/019487A1
Provided herein are methods and intermediates for making (lR,2R,5R)-5-amino-2- methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated w...  
WO/2016/114707A1
The present invention relates to derivatives of dehydroabietic acid useful in treatment ofcardiac arrhythmiaor a hyperexcitablity disease, such as epilepsy or pain, by extracellularly acting on the voltage sensitive domain (VSD) to open ...  
WO/2016/114707A8
The present invention relates to derivatives of dehydroabietic acid useful in treatment ofcardiac arrhythmiaor a hyperexcitablity disease, such as epilepsy or pain, by extracellularly acting on the voltage sensitive domain (VSD) to open ...  
WO/2016/079431A1
The invention relates to 2-octylcyclopropyl-1-carboxylic acid, especially in the form of one of the isomers thereof, which is isolated, or in the form of a mixture of at least two of said isomers. The invention also relates to a method f...  
WO/2016/071849A1
The present invention relates to a process for preparing Lomitapide or its pharmaceutically acceptable salt thereof having high purity with acceptable levels of impurities.  
WO/2016/038379A1
The invention relates to pharmaceutical uses of compounds of formula (II). Particular aspects of the invention relate to the use of those compounds in treating, preventing or ameliorating a seizure-related disorder, bipolar disorder, man...  
WO/2016/026014A8
The present invention provides a perillic acid derivative in the form of a salt having formula II, with anti-cancer activity, in which the counter-ion M+ comprises alkali or alkaline earth metals, such as Na+ (sodium), K+ (potassium), Ca...  
WO/2016/026014A1
The present invention provides a perillic acid derivative in the form of a salt having formula II, with anti-cancer activity, in which the counter-ion M+ comprises alkali or alkaline earth metals, such as Na+ (sodium), K+ (potassium), Ca...  
WO/2016/016641A1
A quaternary ammonium salt of formula wherein each of R1, R2, R3 and R4 is independently selected from an optionally substituted alkyl, alkenyl or aryl group having less than 8 carbon atoms and R5 is hydrogen or an optionally substituted...  
WO/2015/181094A1
The present invention relates to the therapeutic use of derivatives of 1-(2-fluorobiphenyl-4-yl)-cyclopropanecarboxylic acid for improving the cognitive capacity of patients with intellectual disabilities, an IQ of less than 85, diagnose...  
WO/2015/170713A1
Provided is a method for producing a 1,3-di-substituted-cyclobutane-1,2,3,4-tetracarboxylic acid (2) and a dianhydride (3) of the acid with high selectivity and high yield. A 1,3-di-substituted-cyclobutane-1,2,3,4-tetracarboxylic acid (2...  
WO/2015/134710A1
Disclosed herein are compounds of the general Formula (I), and methods of synthesizing substituted bicyclo[1.1.1 jpentanes. The synthetic methods described herein use a [1.1.1]propellane, a Group VIII transition metal compound, a hydride...  
WO/2015/129740A1
 The present invention provides a method for producing an alicyclic polycarboxylic acid capable of keeping the heat removal performance of a reaction mixture stable and obtaining stable reaction results over an extended period of time....  
WO/2015/108170A1
 Provided is a method for obtaining cyclobutanetetracarboxylic acid and/or a dianhydride thereof by using, as the raw material, the residue remaining after a target substance generated in a process for producing a cyclobutanetetracarbo...  
WO/2015/012263A1
An adsorption method for saturated hydrocarbon that causes a saturated hydrocarbon having no more than three carbon atoms to be selectively absorbed by a metal complex including a ligand indicated by formula (1) and metal ion, by causing...  
WO/2014/205392A1
Disclosed herein are cocrystals of dimethyl fumarate and gentisic acid or (+)-camphoric acid. Dimethyl fumarate is a prodrug of methyl hydrogen fumarate. The cocrystals have improved physicochemical properties and are used in treating mu...  
WO/2014/195976A3
The invention disclosed herein is an improved, cost effective, ecofriendly process for purification of Boswellic acid extracted from the gum resin exudates of Boswellia serrata using hydro alcoholic solvents, specifically ethanol, to pro...  
WO/2014/129569A1
A method for producing a metal complex comprising a polycarboxylic acid compound, at least one metal ion, an organic ligand capable of multidentately coordinating with the metal ion and a monocarboxylic acid compound, wherein a metal sal...  
WO/2014/110036A4
Compounds of formula (I): [Formula should be inserted here]; where [Formula should be inserted here], n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed co...  
WO/2014/110388A1
Method to obtain methylene malonate and related monomers following a bis(hydroxymethyl) malonate pathway. A bis(hydroxymethyl) malonate intermediary is subsequently reacted (i.e., subjected to thermolysis) to provide a methylene malonate...  
WO/2014/110036A1
Compounds of formula (I): [Formula should be inserted here]; where [Formula should be inserted here], n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed co...  
WO/2014/102808A1
A commercially viable process for industrial preparation of trans-(l R,2R)-cyclohexane 1,2- dicarboxylic acid represented by compound of Formula-I, wherein the compound has more than 99% HPLC purity. The compound of Formula-I is a key in...  
WO/2014/053618A1
The present invention relates to a method for producing at least one cyclohexanecarboxylic acid or a derivative thereof by bringing into contact at least one corresponding benzene polycarboxylic acid or a derivative thereof with a gas co...  
WO/2014/027777A3
The present invention relates to a novel ursolic acid derivative in an ursolic acid prodrug form, and to a method for preparing same, wherein the novel ursolic acid derivative, an ursolic acid prodrug form which can have excellent pharma...  
WO/2013/190357A1
The present invention provides an improved process for the preparation of a compound of formula (I),  
WO/2013/190357A8
The present invention provides an improved process for the preparation of a compound of formula (I),  
WO/2013/181786A1
Provided in the present invention are various labdane diterpenoid compounds and derivatives thereof for use in preparation of a pharmaceutical composition for preventing or treating neurodegenerative diseases. Also provided in the presen...  
WO/2013/180462A1
The present invention is related to the inventive compositions comprising the extract of pine leaf extract or the compound isolated therefrom. It showed potent inhibitory effect on human papillomavirus (HPV) as well as anti-cancer effect...  
WO/2013/169740A2
Synthetic triterpenoids and methods of using the same to induce gene expression and differentiation of stem or progenitor cells are provided.  
WO/2013/126916A8
The present invention relates to novel non-aqueous gels of natural oils and their derivatives and provides a novel process for the gelation of natural oils and their derivatives that does not require the addition of gellants or the irrev...  
WO/2013/126916A3
The present invention relates to novel non-aqueous gels of natural oils and their derivatives and provides a novel process for the gelation of natural oils and their derivatives that does not require the addition of gellants or the irrev...  
WO/2013/117687A1
The present invention pertains to a method for preparing a carboxylic acid by acidification of a liquid feed comprising a carboxylate salt, which method comprises the steps of - providing a liquid feed comprising magnesium carboxylate; -...  
WO/2013/101719A3
Methods for synthesizing amooranin (25-hydroxy-3-oxoolean-12-en-28-oic acid (AMR) and/or amooranin analogs, including amooranin methyl ester (AMR-Me), by using oleanolic acid in an oxidation process, and therapeutic uses thereof are desc...  
WO/2013/086460A1
A photoacid compound comprising a light absorbing moiety attaching a payload moiety through a linker, in which the linker comprises a geminal dialkyl linked to a carbonyl group attaching the payload moiety, and the linker is configured t...  

Matches 1 - 50 out of 2,165