| Document |
Document Title |
|
JP2003522130A |
The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecano...
|
|
JP2003201274A |
To synthesize a new fluoroalkyl esters and provide new liquid crystal materials and functional materials.This new fluoroalkyl ester has a chemical structure represented by general formula (1) (wherein Rf is a saturated or unsaturated and...
|
|
JP2003519674A |
The present invention provides a method for preparing an ester of betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a method for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzo...
|
|
JP2003096026A |
To provide a new hydroxymethylcyclohexanecarboxylic acids composition having high trans isomer content, used as raw materials of various synthetic resins, intermediates of pharmaceuticals or agrochemicals, various chemicals such as solve...
|
|
JP2003081940A |
To obtain a condensed cyclic hydroperoxide or condensed cyclic alcohol in high selectivity from the corresponding condensed cyclic compound including an aromatic ring-condensed cycloalkane ring.This condensed cyclic hydroperoxide where a...
|
|
JP2003002864A |
To provide a method for producing oxocyclohexyl acetic acid with good productivity by catalytic hydrogenation of hydroxyphenyl acetic acid and a method for producing hydroxyiminocyclohexyl acetic acid with good productivity by reacting t...
|
|
JP2002543125A |
A method of treatment of lymphoproliferative and autoimmune disorders with a new composition of four boswellic acids including beta-boswellic acid, 3-O-acetyl-beta-boswellic acid, 11-keto-beta-boswellic acid, and 3-O-acetyl-11-keto-beta-...
|
|
JP3346571B2 |
Novel indane and indene derivatives are described which are endothelin receptor antagonists.
|
|
JP2002322107A |
To provide a suitable composition for industrial use of which the composition for transportation and/or storage of the compound with a cyclohexane ring and/or aromatic ring having a hydroxyalkyl group, for further particulars, transporta...
|
|
JP2002536382A |
The invention relates to novel betulinic acid derivatives of structural formula having modifications at C2, C3, C17, C20 and/or C29 positions, said derivatives being useful as inhibitors of tumor/cancer cells; process for preparation of ...
|
|
JP3333510B2 |
Compounds illustrated by general formula (I) useful as PDE IV inhibitors and for inhibiting the production of Tumor Necrosis Factor (TNF) are disclosed herein. In formula (I) R1 is C1-12 alkyl unsubstituted or substituted by 1 or more ha...
|
|
JP2002534955A |
The present invention is directed to certain novel compounds represented by structural formula (I) or a pharmaceutically acceptable salt thereof, wherein R<3>, R<6>, R<7>, R<8>, R<11>, R<12>, R<13>, A, Q, W, X, Y, Z and n are defined her...
|
|
JP2002284734A |
To provide a method for producing, from the corresponding rosin, a rosin derivative having keto functional group that is usable as an industrial chemical for pharmaceutical preparations and perfumes or as an intermediate therefor.This me...
|
|
JP2002526517A |
Compounds and methods for treating prostaglandin mediated diseases, and certain pharmaceutical compositions thereof are disclosed. The compounds are represented by formula II:The compounds of the invention are structurally different from...
|
|
JP2002212137A |
To provide new antibiotics exhibiting antibacterial activity capable of specifically suppressing the growth of bacteria belonging to the genus Pasteurella.Antibiotics pasteurestin A and B of the compounds expressed by general formula (I)...
|
|
JP2002523392A |
The invention relates to substituted cinnamic acids and cinnamic acid esters of formula (I), wherein X represents F, Cl or J and R1 and R2 are the same or different and represent hydrogen, an optionally substituted C1-C10-alkyl radical o...
|
|
JP2002201188A |
To provide a most important intermediate for producing cyclopropane carboxylate esters which are insecticidal compounds known as pyrethroids, and equipped with a very good insecticidal characteristic and an extremely low toxicity to mamm...
|
|
JP2002193880A |
To provide a bicyclooctane derivative which is the compound represented by general formula (I), and is useful for prophylaxis and/or therapy of inflammatory disease, diabetic disease, allergic disease, autoimmune disease, osteoporosis, o...
|
|
JP2002186854A |
To provide a method for producing alicyclic compounds by selectively hydrogenating aromatic compounds in an industrially and economically advantageous manner at good efficiency.This method comprises performing a selective hydrogenation b...
|
|
JP2002080353A |
To provide a carcinogenesis promotion inhibitor composition, particularly relating to chemical carcinogenesis, because the two-step mechanical theory of initiation and promotion has been widely recognized in the chemical carcinogenesis a...
|
|
JP2002080421A |
To isolate highly pure shikimic acid from an aqueous mother liquid in a crystallization process.This method for producing the highly pure shikimic acid, characterized by washing the crystallization mother liquor with a water-immiscible o...
|
|
JP3261623B2 |
PURPOSE: To obtain a metal corrosion-inhibiting coating compsn. which is neither carcinogenic nor toxic by compounding an org. film forming binder and a specified ketoacid with a cation, a specified amine compd. or the like. CONSTITUTION...
|
|
JP3238962B2 |
PURPOSE: To prepare a new compd. useful for enhancing gamma-amino butyric acid-induced chlorine currents at a gammer-amino butyric acid receptor/chloride ionophore complex. CONSTITUTION: A compd. of formula I or II (R1 is H, a 1-4C alkyl...
|
|
JP2001518072A |
A novel process for the production of the natural antioxidant, carnosic acid, by extracting it from rosemary leaves with an aqueous solution of a lower alkyl alcohol in the presence of a water soluble acid is described. The extraction of...
|
|
JP2001258583A |
To provide a method for purifying shikimic acid which is capable of effectively separating shikimic acid from dehydroxyshikimic acid and other analogs chemical structures similar to shikimic acid.This method for purifying shikimic acid f...
|
|
JP2001253847A |
To provide a method for enabling the industrial and efficient production of (hydroxyalkyl)cycloaliphatic carboxylic acids at low costs.The (hydroxyalkyl)cycloaliphatic carboxylic acids are produced by performing the ring hydrogenation re...
|
|
JP2001514634A |
2-(substituted benzoyl)-cycloalkyl-1-carboxylic acids of formula (I) wherein E is a C1-C4 alkylene chain in which a carbon atom is optionally substituted; each of R and R1, being the same or different, is hydrogen, halogen, hydroxy, trif...
|
|
JP2001240573A |
To provide a liver disease medical treatment agent.A liver disease medical treatment agent expressed in formula (I) [wherein R1 is a hydroxy group, 1-6C alkoxy group, etc., R2 is -COOR3 (R3 is a hydrogen atom or 1-6C alkyl group), hydrox...
|
|
JP2001199932A |
To provide a benzene derivative useful as an intermediate for pharmaceuticals, agrochemicals, liquid crystals, heat-resistant polymers, liquid crystal polymers, etc. The objective benzene derivative is expressed by general formula [X is ...
|
|
JP2001199884A |
To provide an analgesic agent having analgesic action and anti- inflammatory action without being almost not accompanied by such side effect as recognized in a conventional painkiller. This analgesic agent is obtained by including a subs...
|
|
JP2001506598A |
The present invention relates to asiatic acid derivatives represented by formula (1), and medicines for treating wounds, which contains the same as an active component.
|
|
JP3169144B2 |
PURPOSE: To obtain a new compound capable of exhibiting a thymulin-like activity and useful as a therapeutic agent, etc., for immunodeficiency and autoimmune diseases, etc. CONSTITUTION: A compound of formula I [R1 and R2 are (protected)...
|
|
JP3167811B2 |
PURPOSE: To produce the subject compd. being an important synthetic intermediate of ester having pesticidal activity by passing through a new intermediate. CONSTITUTION: A compd. expressed by formula II or its cyclized lactone expressed ...
|
|
JP2001131114A |
To provide a method for selectively manufacturing a biphenyl derivative using an inexpensive material. The biphenyl derivative of general formula (8) is manufactured by carrying out a reaction of a compound of general formula (1) and a c...
|
|
JP3151074B2 |
PURPOSE: To prepare the subject compound which is an important intermediate for synthesis of an ester having insecticidal activity, through a new halogenated intermediate. CONSTITUTION: In this preparation, 1R,cis-2,2-dimethyl-3-(2-oxopr...
|
|
JP2001089452A |
To obtain a compound having CD40 function-inhibiting action. This pyrimidine derivative is a compound having the general formula (I) {R1, R3 and R4 are each H, OH, a halogen, an alkyl, an alkoxy, an alkylthio, a halogenated alkyl, an ary...
|
|
JP2001504515A |
PCT No. PCT/KR97/00240 Sec. 371 Date May 25, 1999 Sec. 102(e) Date May 25, 1999 PCT Filed Nov. 27, 1997 PCT Pub. No. WO98/23575 PCT Pub. Date Jun. 4, 1998Asiatic acid derivatives having a modified A-ring, as represented by formula 1 are ...
|
|
JP2001081059A |
To easily obtain an optically active 2-phnylcyclopropanecarboxylic acid derivative in an industrial scale useful as an intermediate for pharmaceuticals and agrochemicals by reacting a specific racemic 2- phenylcyclopropanecarboxylic acid...
|
|
JP2001502313A |
Sordarin derivatives are antifungal agents useful in the treatment and/or prevention of human and animal fungal infections, as well as in the control of phytopathogenic fungi in crops.
|
|
JP2001039920A |
To industrially readily produce the subject compound by reacting a racemic body of the subject compound with an optically active amine to precipitate a diastereomer salt as a crystal, separating the obtained crystal, and treating the sep...
|
|
JP2001039923A |
To obtain a new hydronaphthalene derivative effective as an antifungal agent, an anticancer agent or the like, or a raw material therefor, and having a structure obtained by adding a specific substituent group to a compound having a hydr...
|
|
JP2001026564A |
To obtain a new compound having high antifungal activity against fungi causing opportunistic infections diseases, excellent in selectivity, and useful as an antifungal agent or an anticancer agent useful in clinical practices, or as a ra...
|
|
JP2001026567A |
To purify shikimic acid in high yield and high purity by putting a solution containing shikimic acid under a basic condition to dehydrate dehydroshikimic acid as an impurity and isomerize the resultant product to protocatechuic acid, or ...
|
|
JP2001011013A |
To provide a method for purifying shikimic acid, capable of effectively isolating the shikimic acid in a high yield through a process suitable for industrial production, by contacting an aqueous solution containing shikimic acid and havi...
|
|
JP2001500157A |
A reaction between 6-bromo-2-naphthol and dimethyl sulfate is conducted in the presence of substantially stoichiometric amounts of sodium hydroxide and water and in an organic solvent to prevent the formation of sodium methyl sulfate whi...
|
|
JP2000351750A |
To efficiently and selectively isolate and purify the subject compound in high yield by mixing a solution containing shikimic acid with ammonia or an amine, then isolating the shikimic acid as an amine salt, subsequently decomposing the ...
|
|
JP3118939B2 |
PURPOSE: To obtain new optically-active 2-hydroxy-2-norbornanecarboxylic acid useful as a synthetic intermediate for physiologically active substance such as inhibitor of blood agglutination. CONSTITUTION: Optically active (+)-2-hydroxy-...
|
|
JP3104966B2 |
|
|
JP2000256246A |
To inexpensively and simply obtain a cyclopentenone derivative useful as an intermediate for perfumes and medicines by reacting a specific intermediate compound with lead tetraacetate. A production intermediate of formula I is reacted wi...
|
|
JP2000239297A |
To obtain the subject extract which can contribute to effective use for plum and is used as an antioxidant by extracting from the trunks, branches, leaves, etc., of plum trees. This extract is obtained by extracting from at least one obj...
|
