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JP2788427 |
PURPOSE: To provide a method for recovering quinic acid in high efficiency and purity from a stock liquid containing sodium sulfate and quinic acid, dispensing with the marine disposal of a waste liquid discharged in the production of ga...
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JP10130253 |
To obtain the subject new compound useful as a raw material monomer for resins such as polyimide and containing an alkylene chain whose both ends have ether bonds. This compound is represented by formula I [R1 and R2 are each H or an alk...
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JP10101616 |
To obtain a new cyclopropane carboxylic acid-based intermediate compound useful for producing a caronic acid semi-aldehyde derivative having cis-structure used as a raw material of an insecticide. This new cyclopropane carboxylic acid-ba...
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JP10087548 |
To make it possible to obtain the subject compound useful for producing medicines and agrochemicals with excellent yield and purity without requiring severe reactional conditions by using a catalytic transfer hydrogenation. (A) A 1,3-dih...
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JP09328475 |
To obtain the subject derivative, an 1,3,5-triphenylpyrazolyl derivative, having arachidonic acid metabolic route-inhibitory activity, and useful as e.g. an agent for mitigating inflammation, asthma, anaphylaxis, myocardial ischemia, der...
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JP09286755 |
To provide a remedy for diabetes improving only a hyperglycemia state without a grave adverse effect, containing a compound, etc., having a dicarbonyl structure. This remedy contains a compound of formula I [X is formula II, etc., (R4 an...
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JP09278708 |
To obtain a sesquiterpene-based compound useful as a raw material for a medicine, especially an antibacterial agent or an antifungal agent. This sesquiterpene-based compound is shown by formula I (R is H, ammonium, an alkali metal or a l...
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JP2710097 |
PURPOSE: To produce a compound useful for exterminating parasites, nematodes and mites by reacting cyclopropanecarboxylic acids with a reducing agent. CONSTITUTION: A compound represented by formula I (X1 and X2 are each a halogen; R1 is...
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JP09221519 |
To obtain a high-quality fine pattern at a low exposure by using a high- molecular compd. having structural units derived from a (meth)acrylic acid deriv. having a specific group (e.g. a decanediyl group) as a resin for KrF excimer laser...
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JP09183724 |
To obtain a uzedicine useful as an antitumor agent and expected as an antitumor medicine having high safety and little side effect by compounding a specific naphthalene carboxylic acid derivative obtained from propolis or its salt as an ...
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JP09124489 |
To obtain the subject agent containing a specific saponin as an active ingredient, capable of suppressing the production of interleukin-6 caused by a stimulation with various physiological materials, and anticipated as a therapeutic agen...
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JP09104693 |
To obtain new glycosides having action capable of controlling immune system of warm-blooded animals and usable as an active substance in medicines for treating tumor and viral diseases by separating from an aqueous extract of a plant pol...
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JP09040606 |
To obtain the subject compound effectively, without producing by- products and causing the problem of the corrosion of an apparatus, and useful as an intermediate, etc., for a liquid crystal through the hydrogenation of the aromatic ring...
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JP09003000 |
PURPOSE: To provide a method for recovering quinic acid in high efficiency and purity from a stock liquid containing sodium sulfate and quinic acid, dispensing with the marine disposal of a waste liquid discharged in the production of ga...
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JP08325196 |
PURPOSE: To industrially and advantageously obtain a carboxylic acid useful as a raw material, etc., of a solvent-soluble type polyimide in high purity and yield at a short time by carrying out hydrolysis of an alicyclic polycarboxylic e...
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JP2587902 |
PURPOSE: To obtain a new 1-phenylbicyclo[2,2,2]octane compound useful for the treatment of arthritis and inflammatory phenomenon due to denaturation of acute phase protein. CONSTITUTION: The compound of formula I [R1 is a halogen, OH, 1-...
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JP08283116 |
PURPOSE: To obtain a skin lightener and a skin cosmetic which have excellent skin-lightening effect and can prevent and treat skin spots and ephelis caused by sun burn by using a specific 1,3-diarylindan-2-carboxylic acid. CONSTITUTION: ...
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JP08188561 |
To obtain the subject novel compound, which affect certain excitatory amino acid receptors and are useful for treatment of neurological and psychiatric disorders. This compound is shown by formula I [X is (CH2)n; R2 is CO2R4 when R3 is H...
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JP08143508 |
PURPOSE: To provide a method for easily producing a carboxylic acid derivative or its alkali metal salt useful as an intermediate for agricultural chemicals, medicines, etc. CONSTITUTION: An alcohol compound of formula I (R3 is lower alk...
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JP08092141 |
PURPOSE: To obtain a large amount of the compounds useful as a synthetic intermediate for couplers in a high yield by catalytically hydrogenating specific phenols in the presence of a specified catalyst. CONSTITUTION: This method for pro...
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JP08092157 |
PURPOSE: To provide the subject novel compound that originates from a specific microorganism, has strong and selective inhibitory action against catecholamine- O-methyl transferase and is useful for the treatment of Parkinsonism. CONSTIT...
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JP08048652 |
PURPOSE: To produce a compound useful for exterminating parasites, nematodes and mites by reacting cyclopropanecarboxylic acids with a reducing agent. CONSTITUTION: A compound represented by formula I (X1 and X2 are each a halogen; R1 is...
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JP08038193 |
PURPOSE: To effectively obtain optically active tetralin derivatives in an enzymatic process by hydrolyzing the specific racemic esters of tetralin derivatives with lipase to the specific yields, and subsequently inactivating the enzyme ...
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JP07330661 |
PURPOSE: To produce the new dehydroabietic acid derivative capable of improving water and oil repellency, stain proofing properties, heat resistance, etc., therefore, useful as an additive for paper, rubber, ink, etc., having a biologica...
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JP07316188 |
PURPOSE: To industrially and advantageously obtain an oleanolic acid useful as a production intermediate, etc., for endothelin receptor antagonism, etc., by reducing a specific steroidal lactone compound with an alkali(earth)metal in an ...
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JP07316155 |
PURPOSE: To obtain a new compound useful as an antiviral agent. CONSTITUTION: This is a compound of formula I (B is a purine derivative residue such as guanine-9-yl, 2-amino-6-chloropurine-9-yl and 2-acetamino-6- chloropurine-9-yl), e.g....
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JP07291857 |
PURPOSE: To obtain a preventing and therapeutic agent for bone resorption osteopathy such as malignant hypercalcemia, bone Paget disease or osteoporosis containing a glycyrrhetinic acid compound as an active ingredient. CONSTITUTION: Thi...
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JP07291858 |
PURPOSE: To obtain a preventing and therapeutic agent for bone resorption osteopathy such as malignant hypercalcemia, bone Paget disease or osteoporosis containing a gypsogenin compound (salt) as an active ingredient. CONSTITUTION: This ...
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JP07285909 |
PURPOSE: To provide a new phenanthrene derivative having IL-1 inhibiting activity and useful for the treatment of chronic inflammatory diseases. CONSTITUTION: This phenanthrene derivative is a compound selected from the compounds of form...
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JP07285905 |
PURPOSE: To provide a method for selectively oxidizing a primary or secondary alcohol having an easily oxidizable group and a heterocycle to an aldehyde or ketone without changing the group and heterocycle. CONSTITUTION: An aldehyde or k...
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JP07267895 |
PURPOSE: To obtain a new compound useful as a therapeutic agent for diseases owing to leukotriene of pollinosis, bronchial asthma, arthritis, etc. CONSTITUTION: A compound of formula I (R1 is H or a 1-4C alkyl; R2 is H or methyl), e.g. a...
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JP07188099 |
PURPOSE: To efficiently obtain a cyclopentenone derivative useful as a synthetic intermediate for a thyrotropin-releasing hormone analogous compound, etc., in high yield by decarboxylating a cyclopentenone derivative prepared from a spec...
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JP07188204 |
PURPOSE: To safely and simply produce the subject compound in high efficiency by oxidizing a cyclic ketone having an alkoxy group on a carbon at α-position in the presence of a metal compound and an aldehyde using a safe and inexpensive...
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JP07109214 |
PURPOSE: To obtain a sebum secretion promoter having activating action on sebaceous gland function, improving effect on chapped skin by drying. CONSTITUTION: This sebum secretion promoter comprises 0.0001-10.0wt.%, preferably 0.001-3.0wt...
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JP07097349 |
PURPOSE: To provide a novel diphenyl ether deriv. which has high herbicidal activity and is used for a herbicidal compsn. and in a herbicidal method for controlling the growth of undesirable plants. CONSTITUTION: This compd. is represent...
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JP07082213 |
PURPOSE: To obtain the new subject derivative useful as an intermediate for producing an optically active cycloalkenecarbolactone such as optically active mitsugashiwactone. CONSTITUTION: An optically active (2-alkoxycarbonyl-2-cycloalke...
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JP07069974 |
PURPOSE: To obtain a new compound having HMG-CoA reductase-inhibiting action and useful as a synthetic intermediate for antihyperlipemic agents. CONSTITUTION: A compound of formula I (R1 and R2 are each H, a protecting group of OH or R1 ...
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JP07069960 |
PURPOSE: To produce the subject compound industrically and simply by reacting a readily obtainable optically active dioxolan-4-one derivative with cyclopentadiene, then hydrolyzing, catalytically hydrogenating and finally decarboxylating...
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JP07053456 |
PURPOSE: To obtain a new compound useful as an intermediate for synthesis of medicines, agrochemicals, etc., especially a pyrimidine ether derivative-based herbicide. CONSTITUTION: A compound of formula I [R is H, an alkaline metal, ammo...
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JP07053455 |
PURPOSE: To obtain the subject compound useful as a synthetic intermediate for a pyrimidine ether derivative useful as a medicine and an agrochemical by reacting a 2-oxo-1-cycloalkanecarboxylic acid derivative with a metal hydrogen compl...
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JP07053454 |
PURPOSE: To obtain the subject compound useful as a synthetic intermediate for a pyrimidine ether derivative useful as a medicine and an agrochemical by bringing a 2-oxo-1-cycloalkanecarboxylic acid derivative into contact with hydrogen ...
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JP06321853 |
PURPOSE: To simply obtain the subject compound useful as a synthetic intermediate for HMG-CoA reductase inhibitor having decalin skeleton by irradiating Z configuration based on propenyl group at the 6-position of a naphthalene derivativ...
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JP06228044 |
PURPOSE: To obtain a new 1-phenylbicyclo[2,2,2]octane compound useful for the treatment of arthritis and inflammatory phenomenon due to denaturation of acute phase protein. CONSTITUTION: The compound of formula I [R1 is a halogen, OH, 1-...
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JP06211736 |
PURPOSE: To obtain new substd. cyclohexane derivs. which inhibit the glucose-6- phosphatase system of the liver of a mammal and are useful as pharmaceuticals of type II diabetes. CONSTITUTION: The substd. cyclohexane derivs. are compds. ...
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JP06211831 |
PURPOSE: To obtain new fluorone and pyronin Y derivatives having an advantage of absorbing light at high wavelength which are useful as fluorescers and as photoinitiators, in particular as fluorescers and fluorescein dyestuffs in immunoa...
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JP06192155 |
PURPOSE: To obtain a new compound exhibiting an interleukin-1 inhibitory activity and useful as an interleukin-1 inhibitor. CONSTITUTION: A compound of formula I (R1 is a lower alkyl), formula II (R2 is hydroxymethyl or carboxyl), formul...
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JP06157477 |
PURPOSE: To prepare a compound utilizable is herbicides excellent in the selective control of weeds grown among perennial and annual cultivated plants. CONSTITUTION: The compound has formula I [wherein R1 is H, OH, amino, (substituted)al...
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JP06041004 |
PURPOSE: To provide a new compd. which is useful as a starting material for the production of p-cresol. CONSTITUTION: This compd. is 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid. The compd. is obtd. by microbial conversion of p...
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JP06025075 |
PURPOSE: To obtain an oxocarboxylic acid derivative useful for synthesizing liquid crystals, polymer compounds, etc., by reacting a cyclohexenecarboxylic acid derivative with a Lewis acid. CONSTITUTION: A derivative of formula I [R is H,...
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JP06016592 |
PURPOSE: To provide a new compound useful as a herbicide, obtainable in an industrially advantageous way from a feedstock compound with its cyclopropane ring and lower alkyl group at 5-site being in trans-configuration. CONSTITUTION: The...
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