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Matches 1 - 50 out of 4,047

Document Document Title
WO/2019/159596A1
Provided is a method for preparing a coupled body represented by general formula (3), the coupled body being obtained by reacting a compound represented by general formula (1) and a compound represented by general formula (2) in the pres...  
WO/2019/157592A1
A process of producing an edible powder containing cannabis including providing a desired quantity of cannabis oil, a cannabis isolate or a cannabis distillate, mixing the cannabis oil, cannabis isolate or cannabis distillate with a solv...  
WO/2019/155899A1
The present invention relates to a method for producing vanillin, which comprises: a step (A) wherein a vanillin solution is obtained by subjecting a solution that contains crude vanillin and an aliphatic dicarboxylic acid dialkyl ester ...  
WO/2019/145552A1
The present specification discloses methods of purifying one or more cannabinoids from a plant material using unique biphasic solvent systems and liquid-liquid chromatography as centrifugation partitioning chromatography (CPC) or counter...  
WO/2019/126618A1
Multivariate metal-organic framework compositions and methods of producing multivariate metal-organic frameworks. The metal-organic framework including at least one light-emitting linker in an amount sufficient for the composition to pro...  
WO/2019/115597A1
Enantiopure terphenyl presenting two ortho-located chiral axes having the following structural formula (I) : their process of synthesis and their use as mono or bidentate ligands for asymmetric organometallic reactions, as organocatalyst...  
WO/2019/114811A1
The present application provides a method for synthesis of Roxadustat. A compound as represented by formula (VIII) is used as a raw material, and is reacted with phenol, a vinyl-containing ether, an acid, hydroxylamine, and then the prod...  
WO/2019/079222A1
Provided here are therapeutically effective pharmaceutical compositions containing one or more TREX2 inhibitors, and more specifically methods of administering TREX2 inhibitors to increase the effectiveness of a chemotherapeutic agent. A...  
WO/2019/056123A1
Pharmaceutical compositions comprising one or more cannabinoids and a pharmaceutically acceptable carrier are disclosed. The compositions are in a form suitable for topical administration, and are useful in the treatment of pain. The can...  
WO/2019/056128A1
Compositions comprising two or more cannabinoids, a terpene, and a flavonoid suitable for use in treating insomnia are disclosed. In preferred embodiments, the cannabinoids are cannabidiol and tetrahydrocannabinol, while the terpenes and...  
WO/2019/056129A2  
WO/2019/051222A1
The present disclosure provides a benzene fused heterocyclic derivative of Formula (I): --̅-̅-̅ is a single or double bond; n is an integer of 0 or 1; A is -CH2-, -CH(OH)-, or - C(O)-; G is C or N; X is -CH2-, O, or -C(O)-; Y is alkyl...  
WO/2019/044773A1
The functional skin preparation for external use according to the present invention comprises, as active ingredient(s), an aromatic polyhydroxycarboxylic acid derived from a plant-origin saccharide and a microorganism and/or a derivative...  
WO/2019/028600A1
Disclosed is a new process for the production of carboxylated phenol derivatives comprising at least a step of carboxylation of a mixture of (i) phenol derivative and (ii) phenolate derivative, wherein the molar ratio of (i) / (ii) is co...  
WO/2019/025540A1
The invention relates to 3-acyl-benzamides of formula (I) as herbicides. In formula (I) X, Y, Z and Rx represent radicals such as alkyl, cycloalkyl and halogen.  
WO/2019/014255A1
This invention relates to a process for preparing an alkylsalicylic acid. The process comprises reacting salicylic acid with an olefin having at least four carbon atoms at a temperature ranging from about 50 °C to about 200 °C in the p...  
WO/2018/228081A1
Discloses is a method for synthesizing 4-hydroxybenzoic acid by using PX as a raw material. PX is dissolved in an organic solvent and undergoes oxidation reaction with an oxidant under the action of an M-MOF catalyst, after the reaction ...  
WO/2018/218357A1
A method of treating cachexia is provided. The method includes administering to a human in need thereof an effective amount of a complement inhibitor. The complement inhibitor may be a dimer of acetyl salicylic acid, including 5,5'-methy...  
WO/2018/209973A1
The present invention provides compounds as represented by structural formula (I), its S-isomers and R-isomers, and its pharmaceutically acceptable salts. In formula (I), R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 ar...  
WO/2018/205022A1
There is provided an ocular drug delivery formulation comprising a delivery carrier comprising a cellulosic polymer and an anionic polysaccharide and nanoparticles comprising an amphiphilic non-ionizable block copolymer and a cannabinoid...  
WO/2018/177232A1
The present invention provides a complex of formula (I) or a solvate thereof, wherein n is 1 to 4. The present invention also provides a pharmaceutical composition and an application of the pharmaceutical composition in preventing or tre...  
WO/2018/148848A1
A method and cell line for producing phytocannabinoids and phytocannabinoid analogues in yeast. The method applies, and the cell line includes, a yeast cell transformed with a polyketide synthase CDS and a cytosolic prenyltransferase CDS...  
WO/2018/135047A1
Provided are: a method for producing fluorenylidene diallylphenols represented by formula (1), the method including a reaction step for reacting fluorenones represented by formula (2) and allylphenols represented by formula (3) in the pr...  
WO/2018/129609A1
Compounds of formula (II) are useful in modulating voltage-gated sodium channel activity. Their preparation and use for reducing the severity of convulsant activity in a subject, for example in the treatment of epilepsy, is presented.  
WO/2018/126897A1
Disclosed is an application of sodium 5-bromo-2-(α-hydroxypentyl) benzoate (BZP) in drugs treating cardiovascular disease, belonging to the field of pharmaceutical chemistry. Experiments show that BZP has a protective effect with regard...  
WO/2018/129406A1
A variety of amphiphobic porous materials are provided. The materials can include a variety of porous frameworks that have an outer surface functionalized by a plurality of perfluoroalkyl moieties. By careful selection of appropriate per...  
WO/2018/073474A1
The present invention relates to a new series of compounds derived from 2,4-dihydroxybenzoic acid. The invention also relates to a pharmaceutical composition that comprises said compounds and to the use thereof in the treatment or preven...  
WO/2018/052936A1
Provided herein are therapeutic acrylate compounds useful as medical adhesives, comprising a therapeutic agent covalently linked to a methacrylate or cyanoacrylate moiety. Adhesive compositions and kits, such as liquid sutures and bone c...  
WO/2018/052037A1
The present invention addresses the problem of providing a novel branched fluorine-containing compound. The problem is solved by a branched fluorine-containing compound represented by formula (1): [in the formula, L represents a predeter...  
WO/2018/037115A1
The present invention provides an aqueous composition comprising a silicon complex. The composition comprises (i) a monomeric organosilanolate that comprises 1 to 3 oxygen atoms per silicon atom, said organosilanolate being of formula (R...  
WO/2018/025259A1
Naphthoquinone compounds that induce the formation of reactive oxygen species (ROS) are disclosed. Process of preparing the naphthoquinone compounds are also disclosed. Uses of the compounds for treating a disease or disorder are also di...  
WO/2018/018091A1
The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.  
WO/2018/011741A1
Disclosed are methods for preparing a levulinic acid mixture in a reaction vessel that is, for example, suitable for use in synthesizing a glyceryl ketal of levulinic acid or an ester of levulinic acid comprising distilling a combination...  
WO/2017/222921A1
Substituted derivatives of 2-hydroxyisophthalic acid are provided, as well as new synthetic routes for making 2-hydroxyisophthalic acid and the substituted derivatives. Potential uses of the derivatives in a variety of applications are a...  
WO/2017/218065A1
A MOF production system and method of making are detailed for continuous and controlled synthesis of MOFs and MOF composites. The system can provide optimized yields of MOFs and MOF composites greater than or equal to 95%.  
WO/2017/209458A1
The present invention relates to a novel method for preparing 4'-hydroxy-4-biphenylcarboxylic acid, which is prepared through a hydrolysis reaction from a compound of R1-COO-Ph-Ph-CO-CR-Y. In the formula: R1 is a C1-6 alkyl, cycloalkyl o...  
WO/2017/207346A1
The present disclosure in general relates to a process for reducing impurities, i.e. undesirable components, present in a cashew nut shell liquid (CNSL) using at least one selective nanofiltration membrane. It further provides new produc...  
WO/2017/206468A1
The present invention relates to a technique for mild oxidation of lignite. Provided is a method using oxygen gas under standard pressure as an oxidant for catalytic oxidation of a lignite. The method uses oxygen gas as the oxidant for m...  
WO/2017/199227A1
The present invention relates to a simple economical process for the preparation of 3,4- dihydroxy-2-methyl benzoic acid C1-4 alkyl ester and novel intermediates for use in the process.  
WO/2017/167985A1
A subject matter of the present invention is the cosmetic use of at least one compound of formula (I): in which: (II) denotes a divalent radical chosen from a carbon-carbon single bond *−CH2−CH2−* or double bond *−CH=CH−*, of Z...  
WO/2017/167180A1
The present invention provides a vortioxetine pamoic acid salt, which includes a crystal form, a solvate or an amorphous substance of the vortioxetine pamoic acid salt. The present invention provides a preparation method and use of the v...  
WO/2017/170859A1
The purpose of the present invention is to provide a compound that inhibits the collagen binding function of an HSP47 essential for the extracellular secretion of collagen. The present invention provides a bisaryl derivative indicated by...  
WO/2017/134513A1
The invention relates to novel compounds of general formula (I), as well as the use of said compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular...  
WO/2017/111179A1
The present invention provides a cocrystal of (S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-1 H-1,2,4-triazol-5(4H)-one and an organic acid capable of forming a cocrystal with the compound. Specific cocrystals prepared are c...  
WO/2017/092034A1
Provided is a method for synthesizing a gasoline additive alkyl formamide phenyl ether, comprising: (a) adding hydroxybenzoic acid, alkali, alkylation reagent, and solvent to a four-necked flask; the molar ratio of said hydroxybenzoic ac...  
WO/2017/029868A1
A method according to the present disclosure is a method for separating an unsaturated hydrocarbon that has 2 to 3 carbon atoms from a halogenated unsaturated carbon compound that is produced by substituting at least one of hydrogen atom...  
WO/2017/031161A1
Methods and compositions for inhibiting expression of ASC, expression of NLRP3, and/or formation of NLRP3 inflammasome complex by using diacerein or its analogs are provided. Also provided are methods and compositions for the treatment a...  
WO/2017/006638A1
Provided is a polycarboxylic acid containing a condensed aromatic ring, said polycarboxylic acid being represented by formula (1) (X represents an anthracene ring or the like, and R1 and R2 represent a hydroxyl group or the like). Furthe...  
WO/2016/181800A1
An oxidation reactor with which hydrocarbons can be oxidized efficiently in terms of both reaction efficiency and energy efficiency is provided. This oxidation reactor is equipped with: a liquid introduction channel through which a liqui...  
WO/2016/167225A1
The purpose of the present invention is to provide a method for producing 2-halogenated benzoic acids, the method imparting high regioselectivity (high selectivity) and having a shorter reaction time than does the conventional reaction. ...  

Matches 1 - 50 out of 4,047