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Matches 1 - 50 out of 3,973

Document Document Title
WO/2018/011741A1
Disclosed are methods for preparing a levulinic acid mixture in a reaction vessel that is, for example, suitable for use in synthesizing a glyceryl ketal of levulinic acid or an ester of levulinic acid comprising distilling a combination...  
WO/2017/222921A1
Substituted derivatives of 2-hydroxyisophthalic acid are provided, as well as new synthetic routes for making 2-hydroxyisophthalic acid and the substituted derivatives. Potential uses of the derivatives in a variety of applications are a...  
WO/2017/218065A1
A MOF production system and method of making are detailed for continuous and controlled synthesis of MOFs and MOF composites. The system can provide optimized yields of MOFs and MOF composites greater than or equal to 95%.  
WO/2017/209458A1
The present invention relates to a novel method for preparing 4'-hydroxy-4-biphenylcarboxylic acid, which is prepared through a hydrolysis reaction from a compound of R1-COO-Ph-Ph-CO-CR-Y. In the formula: R1 is a C1-6 alkyl, cycloalkyl o...  
WO/2017/207346A1
The present disclosure in general relates to a process for reducing impurities, i.e. undesirable components, present in a cashew nut shell liquid (CNSL) using at least one selective nanofiltration membrane. It further provides new produc...  
WO/2017/206468A1
The present invention relates to a technique for mild oxidation of lignite. Provided is a method using oxygen gas under standard pressure as an oxidant for catalytic oxidation of a lignite. The method uses oxygen gas as the oxidant for m...  
WO/2017/199227A1
The present invention relates to a simple economical process for the preparation of 3,4- dihydroxy-2-methyl benzoic acid C1-4 alkyl ester and novel intermediates for use in the process.  
WO/2017/167985A1
A subject matter of the present invention is the cosmetic use of at least one compound of formula (I): in which: (II) denotes a divalent radical chosen from a carbon-carbon single bond *−CH2−CH2−* or double bond *−CH=CH−*, of Z...  
WO/2017/167180A1
The present invention provides a vortioxetine pamoic acid salt, which includes a crystal form, a solvate or an amorphous substance of the vortioxetine pamoic acid salt. The present invention provides a preparation method and use of the v...  
WO/2017/170859A1
The purpose of the present invention is to provide a compound that inhibits the collagen binding function of an HSP47 essential for the extracellular secretion of collagen. The present invention provides a bisaryl derivative indicated by...  
WO/2017/134513A1
The invention relates to novel compounds of general formula (I), as well as the use of said compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular...  
WO/2017/111179A1
The present invention provides a cocrystal of (S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-1 H-1,2,4-triazol-5(4H)-one and an organic acid capable of forming a cocrystal with the compound. Specific cocrystals prepared are c...  
WO/2017/092034A1
Provided is a method for synthesizing a gasoline additive alkyl formamide phenyl ether, comprising: (a) adding hydroxybenzoic acid, alkali, alkylation reagent, and solvent to a four-necked flask; the molar ratio of said hydroxybenzoic ac...  
WO/2017/029868A1
A method according to the present disclosure is a method for separating an unsaturated hydrocarbon that has 2 to 3 carbon atoms from a halogenated unsaturated carbon compound that is produced by substituting at least one of hydrogen atom...  
WO/2017/031161A1
Methods and compositions for inhibiting expression of ASC, expression of NLRP3, and/or formation of NLRP3 inflammasome complex by using diacerein or its analogs are provided. Also provided are methods and compositions for the treatment a...  
WO/2017/006638A1
Provided is a polycarboxylic acid containing a condensed aromatic ring, said polycarboxylic acid being represented by formula (1) (X represents an anthracene ring or the like, and R1 and R2 represent a hydroxyl group or the like). Furthe...  
WO/2016/181800A1
An oxidation reactor with which hydrocarbons can be oxidized efficiently in terms of both reaction efficiency and energy efficiency is provided. This oxidation reactor is equipped with: a liquid introduction channel through which a liqui...  
WO/2016/167225A1
The purpose of the present invention is to provide a method for producing 2-halogenated benzoic acids, the method imparting high regioselectivity (high selectivity) and having a shorter reaction time than does the conventional reaction. ...  
WO/2016/145479A1
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of fibrosis and fibrosis-related conditions.  
WO/2016/117295A1
The present invention addresses the issue of providing a novel production method for a more thermodynamically stable inclusion compound having, as the host compound therefor, at least one type selected from the group consisting of 1, 1, ...  
WO/2016/117298A1
Provided is a novel crystalline polymorphism of an inclusion compound (molar ratio 1:1) comprising 5-hydroxyisophthalic acid and 2-ethyl-4-methyl imidazole. A novel crystalline polymorphism of an inclusion compound (molar ratio 1:1) comp...  
WO/2016/112875A3
The present invention relates to a diphenyl derivative and uses thereof, the diphenyl derivative having the structure as indicated in formula (I) defined in the description. The uses refer to the uses of the diphenyl derivative, pharmace...  
WO/2016/112875A2
The present invention relates to a diphenyl derivative and uses thereof, the diphenyl derivative having the structure as indicated in formula (I) defined in the description. The uses refer to the uses of the diphenyl derivative, pharmace...  
WO/2016/114668A1
The present invention is directed to a method for preparing a final phenolic product from biomass comprising the steps of providing a furanic compound obtainable from biomass; reacting the furanic compound with a dienophile to obtain a p...  
WO/2016/081658A1
Methods for making prodrugs of trepreostinil and treprostinil derivatives are provided. Specifically, methods are provided herein for producing prostacyclin compounds comprising treprostinil covalently linked to a linear C5-C18 alkyl, br...  
WO/2016/034126A1
A compound of formula (I) is disclosed, which has a low toxicity, can significantly inhibit the migration and invasion of tumor cells in vitro, and can inhibit tumor metastasis in vivo in mice at low concentration, while showing notable ...  
WO/2016/016641A1
A quaternary ammonium salt of formula wherein each of R1, R2, R3 and R4 is independently selected from an optionally substituted alkyl, alkenyl or aryl group having less than 8 carbon atoms and R5 is hydrogen or an optionally substituted...  
WO/2016/011319A1
The present technology relates to synthesis of compositions comprising salicylates, polysalicylates and other derivatives of salicylic acid, and personal care and pharmaceutical compositions comprising the same.  
WO/2015/175984A1
Described herein are compounds which can be used in topical liquids, creams, or other dosage forms such as solids, for reducing intraocular pressure, treating glaucoma, growing hair, treating wounds, or other medical and/or cosmetic uses.  
WO/2015/169854A1
The invention provides a method for the preparation of regioisomerically pure intermediates which are useful for the preparation of carboxy-fluorescein-type compounds. Such compounds have broad applications within bio-conjugation and/or ...  
WO/2015/159098A1
There are provided compounds of the formula D-S1-A-S2-B1 wherein A comprises a 2,7- disubstituted 9,9-fluoroalkyl fluorene diradical of the formula wherein S1, S2, D and B1 have meanings given in the description that are useful as charge...  
WO/2015/157082A1
Disclose are methods for minimizing the recycle of para-toluic acid within a terephthalic acid purification plant. Specifically, the disclosed methods remove a portion of the p-toluic acid from the pure plant flash condensate and recycle...  
WO/2015/157239A1
The disclosure provides for metal organic frameworks (MOFs) which comprise a plurality of SBUs linked together by functionalized or multivariate BTB-based linking ligands. The disclosure further provides for the use of these MOFs in vari...  
WO/2015/157187A1
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor positive allosteric modulators (PAMS), compositions comprising the compounds, and methods of using the compounds and compositions comprising the c...  
WO/2015/137272A1
The present invention provides a porous structure containing at least two kinds of metal ions and an organic ligand, said porous structure being characterized in that the at least two kinds of metal ions are homogeneously mixed together ...  
WO/2015/124651A1
The present invention relates to a process for providing a compound of formula (IV):wherein R1 and R2 are each independently C1-C4 alkyl, and Hal is independently Cl or Br, the process comprising the steps of: (i) reacting a compound of ...  
WO/2015/120115A1
Compositions for use in methods of treating and/or inhibiting a pathologic ocular condition, as well as methods of producing and using same, are disclosed.  
WO/2015/110502A1
A composition comprising a polymer, or an oligomer, comprising cross-linking moiety, which moiety comprises a carbon-carbon triple bond; and a molecule comprising a carbon-carbon triple bond, wherein the thermal curing behavior of said m...  
WO/2015/092720A1
Provided herein are metabolites of N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)- 2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide (Sonidegib, LDE225) that modulate the activity of the Hedgehog signaling pathway and tha...  
WO/2015/086698A1
The present invention relates to a process for providing dihalogen substituted salicylic acid derivativesof formula (II).  
WO/2015/078920A1
The present invention relates to a process for depolymerization of lignin, comprising a step of oxidation of non-phenolic lignin by bringing together, in at least one solvent, non-phenolic lignin, laccase, a redox mediator and an oxygen ...  
WO/2015/067494A1
The present invention relates to a process for providing: a compound of formula (IV): wherein R1 is hydrogen or -(C1-C4)alkyl, R2 is -(C1-C4)alkyl, and each Hal is an independently selected halogen, the process comprising the step of: Re...  
WO/2015/066693A1
The disclosure provides for Metal-Organic Frameworks comprising M2 (m-dobdc) -based cores, and methods of use thereof, including gas separation, gas storage, sensing, and other applications utilizing a high density of exposed metal catio...  
WO/2015/055116A1
An in-depth study is performed on selaginella pulvinata extractives in the present invention, and it is found that the selaginella pulvinata extractives have a significant anti-inflammatory activity. Multiple column chromatography separa...  
WO/2015/027669A3
Disclosed are a phenyl-substituted compound with structures represented by formula (1) and formula (2), a pharmaceutical composition and uses thereof. The compound can remarkably show in vivo and in vitro that the compound can kill and/o...  
WO/2015/027669A2
Disclosed are a phenyl-substituted compound with structures represented by formula (1) and formula (2), a pharmaceutical composition and uses thereof. The compound can remarkably show in vivo and in vitro that the compound can kill and/o...  
WO/2015/010666A3
A phenol derivative and a use thereof are disclosed. The phenol derivative comprises a compound as represented by structural formulas (I), (II) or (III) or a pharmaceutically acceptable salt, ester and amide thereof. In structural formul...  
WO/2015/010666A2
A phenol derivative and a use thereof are disclosed. The phenol derivative comprises a compound as represented by structural formulas (I), (II) or (III) or a pharmaceutically acceptable salt, ester and amide thereof. In structural formul...  
WO/2015/007181A1
Disclosed are 5-bromine-2-(α-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and a preparation method thereof, relating to the field of medicinal chemistry. The 5-bromine-2-(α-hydroxypentyl)benzoic acid sodium salts...  
WO/2015/002151A1
Provided is a method for stabilizing DHNA or a vitamin contained in a food, a beverage and or like under an environment which can be subjected to natural light or artificial light, e.g., a transparent container, without requiring the use...  

Matches 1 - 50 out of 3,973