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WO/2018/185495A1 |
The invention relates to novel compounds with the ability to link an immune response to a defined therapeutic target, to the use of said compounds in treating cancer and infectious diseases, to compositions containing said compounds, pro...
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WO/2018/177588A1 |
The invention relates to novel ester compounds based on bi-, tri- or higher functional carboxylic acids of general formula (I) and to a method for the production thereof and the use thereof in lubricants.
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WO/2018/177114A1 |
The new compound provided by the applicant is a salicylic acid-based fumarate derivative having a general structural formula (A): wherein in the general structural formula (A), R1 is one of H+, Na+, K+ or NH4+, and R2 is an esterified pr...
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WO/2018/177661A1 |
The invention relates to a new type of process for synthesizing fluorinated cyclic aliphatic compounds from the analogous aromatic compounds by means of hydrogenation with an Rh-carbene catalyst system.
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WO/2018/180716A1 |
The present invention provides a polymerizable compound production method that enables production of, in high yield, a polymerizable compound used for producing an optical film or the like. The polymerizable compound production method ac...
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WO/2018/178693A1 |
A quaternary ammonium salt of formula (I): wherein X is a linking group; Y is O, NH or NR1 wherein R1 is H or an optionally substituted hydrocarbyl group; Q+ is a moiety that includes a quaternary ammonium cation; A- is an anion; R2 is a...
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WO/2018/179868A1 |
The disclosure of the present application provides: a polyol composition for a polyurethane resin; a polyurethane resin-forming composition; and a composite material, all of which can be used to form a polyurethane resin which has a low ...
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WO/2018/183788A1 |
Disclosed is a chemical process of preparing dehydrohedione from Hedione via α-chlorination and elimination steps. The process can be conducted in a one-pot process or in a continuous reactor system. Accordingly, a simple and cost effec...
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WO/2018/172783A1 |
There is described a method of reducing polymer tar build-up in the production of methyl methacrylate and/or methacrylic acid by the acetone cyanohydrin process. In the method a stabiliser is contacted with the amide stage reaction mediu...
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WO/2018/175332A1 |
The metal-catalyzed alkoxycarbonylation of a lactone is a method of alkoxycarbonylating a δ-lactone, specifically 3-ethylidene-6-vinyltetrahydro-2H-pyran-2-one. The method includes combining the δ-lactone with an alcohol in an organic ...
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WO/2018/169181A1 |
The present application relates to a method for efficiently producing an alkyl lactate from a byproduct or poly(lactic acid) (PLA), which is generated in the process of converting lactic acid into a lactide.
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WO/2018/168778A1 |
Provided is a polymerizable compound useful for preparing a polymer that enables the production of a film, such as an optical film, having a good balance of lightness and saturation, and can improve inverse wavelength dispersibility on t...
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WO/2018/167718A1 |
A method for the manufacture of a diester of terephthalic acid includes reacting terephthalic acid and a C6-18 alkyl monohydric alcohol in the presence of a catalyst having the formula MO[CH3COCH=C(0-)CH3]2 wherein M = Ti, Zr, or Hf, und...
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WO/2018/167264A1 |
The present invention relates to a phenalene-1-one compound, a photosensitizer composition comprising said phenalene-1-one compound, an article comprising said phenalene-1-one compound and/or photosensitizer composition and the use thereof.
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WO/2018/170371A1 |
Provided herein are novel polyaromatic compounds which, upon cure, produce high refractive index polymers. In accordance with certain aspects of the present invention, there are provided high refractive index formulations containing the ...
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WO/2018/164226A1 |
Provided is a method for producing a high-quality (meth)acrylate that has little coloration. The present invention relates to a method for producing a (meth)acrylate comprising steps 1 through 3 which are performed in order. ○ Step 1 A...
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WO/2018/164662A1 |
A resveratrol ester has the following structure: (I). R1, R2 and R3 are H or (II). Each R4 is independently a carbon chain of 2 to 4 carbon atoms comprising a terminal carboxylic acid moiety, a carbon chain of 1 to 5 carbon atoms compris...
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WO/2018/162739A1 |
The present invention relates to a process for preparing a mixture M1 of enol phosphate isomers devoid of (E,E) isomer and comprising at least 98% of (E,Z) isomer, at least 0.1% of (Z,Z) isomer and at least 0.1% of (Z,E) isomer, comprisi...
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WO/2018/160879A3 |
Disclosed are multifunctional compounds represented by structural formula (I), methods of producing compounds represented by structural formula (I) and their use in inhibiting corrosion in corrodible material.
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WO/2018/160932A1 |
Methods of preparing a polyaspartic ester composition comprise reacting a primary diamine reactant composition with a diester reactant composition under conditions to prepare a polyaspartic ester composition having a primary amine value ...
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WO/2018/157232A1 |
Compositions comprising modulators of N-terminus activation of the androgen receptor, such as EPI-002 and EPI-506, and a second therapeutic agent are provided. Use of such compositions for treatment of various indications, including pros...
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WO/2018/159846A1 |
The present invention provides a production method for an α,β-unsaturated acid ester or an α-haloester, the method being capable of producing the α,β-unsaturated acid ester or α-haloester through a few steps. The method of the pres...
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WO/2018/160879A2 |
Disclosed are multifunctional compounds represented by structural formula (I), methods of producing compounds represented by structural formula (I) and their use in inhibiting corrosion in corrodible material.
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WO/2018/155583A1 |
[Problem] To provide a thermochromic color memorizing composition, which effectively exhibits a capability of alternately memorizing and holding colors and is applicable to various fields, and a thermochromic color memorizing microcapsul...
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WO/2018/154048A1 |
The invention provides an improved method of isolating the 3-(E)-isomer of an unsaturated carboxylic acid from a mixture of corresponding (E/Z)isomers. More particularly, the present invention relates to an improved method for the biocat...
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WO/2018/153727A2 |
The present invention relates to a process for the carbonylation of allyl alcohols at low temperature, low pressure and/or low catalyst load. In an alternative embodiment, an acylation product of allyl alcohol is used for carbonylation. ...
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WO/2018/154314A1 |
A method of processing an aqueous hemicellulosic stream containing lignin, comprising: (a) contacting an aqueous hemicellulosic stream containing lignin with a C3-8 alkyl alcohol at elevated temperature and acidic pH; (b) separating the ...
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WO/2018/154244A1 |
The invention relates to a method for the synthesis of pheromones functionalised on one of the ends thereof and comprising at least two conjugated double bonds with a majority stereochemical configuration (E, Z). The reaction is carried ...
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WO/2018/152428A1 |
This application relates to compounds prepared from cosmetically acceptable ingredients, methods of preparation thereof, and use thereof. Compounds are of formula (I) U-C-B, or salts thereof, wherein U, C and B are moieties of cosmetical...
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WO/2018/150906A1 |
This liquid crystal display device 10 is provided with: a pair of substrates which have conductive films 14, 15, respectively; a liquid crystal layer 12 which is arranged between the pair of substrates and contains liquid crystals; and a...
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WO/2018/146264A1 |
The present invention relates to purification methods of pleuromutilin (I) by means of crystallisation and/or recrystallisation. The process according to the present invention is carried out in the presence of i-propylacetate.
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WO/2018/147051A1 |
A solid electrolyte composition which contains an inorganic solid electrolyte that has ion conductivity of a metal in group 1 or group 2 of the periodic table and a binder that has a specific constituent; a solid electrolyte-containing s...
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WO/2018/148721A1 |
The present invention includes methods and compositions that inhibit AKR1C3 enzymatic activity and consequently reduces androgen receptor (AR) transactivation, AR and prostate specific antigen (PSA) expression levels in, for example, pro...
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WO/2018/147094A1 |
A compound represented by formula (I). (In formula (I), each of R1 and R2 independently represents a hydrogen atom or a methyl group; each of X1 and X2 independently represents a group that is represented by one of formula (X1-1) to form...
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WO/2018/145622A1 |
Provided in the present invention is a method for preparing a salvianolic acid A salt, the preparation method being: dissolving salvianolic acid A in water, then adjusting the pH value to be 1.2-5.5 by using an aqueous solution of a basi...
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WO/2018/147373A1 |
A tetracarboxylic acid dianhydride which is composed of at least one acid dianhydride (A) selected from the group consisting of compounds having an endo/exo type steric structure represented by a specific general formula and enantiomers ...
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WO/2018/146306A1 |
The invention pertains to a process for preparing a compound of formula (1), wherein R1 is independently chosen from C1-C6 alkyl, cycloalkyl, aralkyl and aryl, and R2, R3 and R4 are independently chosen from hydrogen and C1-C6 alkyl, cyc...
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WO/2018/143156A1 |
The present invention pertains to: a solution that contains a diketone compound having an alkoxy group, dialkylzinc represented by general formula (1) and/or a partial hydrolysate of said dialkylzinc, and a solvent; and a method for prod...
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WO/2018/141961A1 |
The present invention relates to a process for the manufacturing of 1-aryl-1-trifluoromethylcyclopropanes, which serve as intermediates for the manufacturing of calcium T channel blockers of the general formula (A) which are described in...
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WO/2018/138686A1 |
Processes for producing a disubstituted oxalate are disclosed. The process includes contacting a cesium salt with one or more alcohols and carbon dioxide (CO2) under reaction conditions sufficient to produce a composition comprising a di...
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WO/2018/137502A1 |
The present invention relates to the field of pharmaceutical chemistry, and in particular, to a crystal form of salvianolic acid A, and a method for preparing same. The X-ray powder diffraction pattern of a crystal form I shows character...
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WO/2018/139507A1 |
The present invention addresses the problem of controlling the alignment of liquid crystal molecules of a liquid crystal display element not having an alignment film by using a non-colored alignable monomer, and of providing a liquid cry...
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WO/2018/138025A1 |
The invention relates to a method for producing norbornyl (meth)acrylate by reacting norbornene with (meth)acrylic acid in the presence of boron trifluoride as a catalyst, characterised in that e) boron trifluoride is added to (meth)acry...
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WO/2018/138689A1 |
Processes for producing a disubstituted oxalate are disclosed. The process includes contacting a cesium salt with one or more alcohols and carbon dioxide (CO2) under reaction conditions sufficient to produce a composition comprising a di...
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WO/2018/138369A1 |
The present invention relates to new malodour-counteracting agents of formula (I) or stereoisomers thereof, particularly useful in blocking the olfactory perception of androstenone, Formula (I), wherein R1, R2, R3,R4, R5, R6, R7 and X ha...
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WO/2018/133972A1 |
The invention relates to glycerol (meth)acrylate carboxylic esters which have a long shelf life as well as to a process for synthesizing said esters.
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WO/2018/134871A1 |
Provided is an additive for an optical resin comprising a (meth)acrylate compound represented by general formula (1). [In general formula (1), X is each independently a fluorine atom or a methyl group that has at least one hydrogen atom ...
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WO/2018/132660A1 |
Disclosed herein are inhibitors of the Integrator complex, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable...
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WO/2018/129609A1 |
Compounds of formula (II) are useful in modulating voltage-gated sodium channel activity. Their preparation and use for reducing the severity of convulsant activity in a subject, for example in the treatment of epilepsy, is presented.
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WO/2018/128314A1 |
The present invention relates to a plasticizer composition in which three types of cyclohexane 1,4-diester-based compounds prepared through transesterification and hydrogenation are mixed, the plasticizer composition having an alkyl subs...
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