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Matches 51 - 100 out of 1,215

Document Document Title
WO/2013/044123A1
The present invention provides for methods for therapeutic use of dimeric compound B3C and related compounds to treat Parkinson's disease (PD) and Parkinsonism. B3C is neuroprotective and has utility as a therapeutic agent for the treatm...  
WO/2013/033430A1
Acridine containing cispiaiin compounds have been disclosed that show greater efficacy against cancer than other cisplatin compounds. Methods of delivery of those more effective eisp!aiin compounds to the nucleus in cancer ceils is discl...  
WO/2013/026866A3
The present invention relates to methods of controlling or preventing phytopathogenic diseases on useful plants or on propagation material thereof comprising applying to useful plants, the locus thereof or propagation material thereof a ...  
WO/2013/022494A3
Sensors and methods for determination of analytes are provided. Analytes including explosives (e.g., RDX or PETN) may be determined by monitoring, for example, a change in an optical signal of a material upon exposure to the analyte. In ...  
WO/2013/011954A1
An organic electroluminescence element using a compound represented by general formula (1) in a light-emitting layer exhibits a high emission efficiency and is inexpensive to manufacture. (1) At least one of R1 through R8 and R17 represe...  
WO/2012/147330A1
[Problem] To provide an organic compound, as a material for a highly efficient and highly durable organic electroluminescent element, which exhibits excellent hole injection and transportation capabilities and has electron stopping abili...  
WO/2012/141249A1
An organic electroluminescent element using a compound represented by general formula (AA) has high luminous efficiency and excellent color purity, while being suppressed in chromaticity change due to driving deterioration. (In the formu...  
WO/2012/137741A1
A method for purifying an organic material, which can sublimate and purify an organic material having a high sublimation temperature and high heat resistance within a short time with high purity and high yield. The method comprises: redu...  
WO/2012/128898A1
Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA s...  
WO/2012/049828A1
An aromatic heterocyclic derivative represented by formula (1); a material for an organic electroluminescent element; and an organic electroluminescent element comprising the derivative or the material.  
WO/2012/036573A3
The present invention relates to novel protein modulators capable of altering function of the mutant CFTR protein and their use for treating diseases associated with CFTR protein malfunction. The invention provides compositions, pharmace...  
WO/2012/036573A2
The present invention relates to novel protein modulators capable of altering function of the mutant CFTR protein and their use for treating diseases associated with CFTR protein malfunction. The invention provides compositions, pharmace...  
WO/2012/033061A1
Provided is an organic electroluminescent element having superior luminous efficiency and durability as well as a low drive voltage and superior heat resistance. The organic electroluminescent element has a pair of electrodes formed on a...  
WO/2012/031534A1
Disclosed are 1,2,3,4,5,6,7,8-octohydro-9-phenylacetamidoacridine and salts thereof, as well as a preparation method and pharmaceutical use thereof. The compound can be used in the preparation of a medicament for treating cardiovascular ...  
WO/2012/032990A1
To provide a compound which contributes to providing a photoelectric conversion element that exhibits high photoelectric conversion efficiency, low dark current, and rapid response, and which does not decompose during vapor deposition. T...  
WO/2012/028167A3
Acridinium esters show strong chemiluminescence under reducing conditions. Reducing conditions involve reduced metal ions or reduced aromatic quinones. This chemistry can be used in the detection and quantification of acridinium ester, (...  
WO/2012/029253A1
Nitrogen-containing aromatic heterocyclic derivative represented by the formula. X1 to X3 represent a single bond, CRaRb, NRc, an oxygen atom, or a sulfur atom. In the case where all of X1 to X3 have a single bond, at least one of Ara, A...  
WO/2012/024670A3
The disclosure provides methods of treating glioblastoma, methods of screening for compounds that treat glioblastoma, and pharmaceutical compositions useful the treatment of glioblastoma.  
WO/2012/024670A2
The disclosure provides methods of treating glioblastoma, methods of screening for compounds that treat glioblastoma, and pharmaceutical compositions useful in the treatment of glioblastoma.  
WO/2011/156889A1
There is provided modulators of Nrf2 protein which comprises a compound which binds at least one of the BTB domain, IVR domain and Kelch domain of Keap1 protein, activating or inhibiting Nrf2. There is also provided pharmaceutical compos...  
WO/2011/155169A1
Provided are organic compounds that, as materials for high efficiency, high durability organic electroluminescence elements, have excellent positive hole-injection and/or -transport capabilities, are able to block electrons, are very sta...  
WO/2011/127406A3
The present disclosure is directed to compounds of Formula I: which are inhibitors of Haspin kinase and DYRK kinases. The compounds of the present disclosure, and compositions thereof, are useful in the treatment of disease related to Ha...  
WO/2011/127406A2
The present disclosure is directed to compounds of Formula I: which are inhibitors of Haspin kinase and DYRK kinases. The compounds of the present disclosure, and compositions thereof, are useful in the treatment of disease related to Ha...  
WO/2011/123911A1
The present invention can be used as an antitumoral medicament for testosterone-dependent tumours, in particular prostate cancer. The invention is a molecular compound formed by testosterone molecules chemically linked to molecules of a ...  
WO/2011/105700A1
Provided are novel organic electroluminescent compounds, and organic electroluminescent devices comprising the same. Since the organic electroluminescent compounds exhibit high luminous efficiency in blue color, and excellent life proper...  
WO/2011/099606A1
A photoelectric element includes a conductive layer, an organic photoelectric layer, a blocking layer and a transparent conductive layer, the organic photoelectric layer contains a p type organic photoelectric material having a glass tra...  
WO/2011/093603A1
Provided are a novel organic electroluminescent compound and an organic electroluminescent device using the same. Since the organic electroluminescent compound exhibits good luminous efficiency and excellent life property, it may be used...  
WO/2011/086178A1
The present invention concerns the discovery of new selective inhibitors of ubiquitin specific proteases, their process of preparation and their therapeutic use.  
WO/2011/070177A2
Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFRα receptor molecules, ...  
WO/2011/070177A3
Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFRα receptor molecules, ...  
WO/2011/062182A1
Provided are a photo-acid generator having good development properties and a cation polymerization initiator having good curing properties, and also provided are a resist composition and cation polymerizable composition that use the phot...  
WO/2011/060228A1
Hydrophilic, chemiluminescent acridinium compounds containing zwitterions are disclosed. These acridinium compounds, when used as chemiluminescent labels in immunochemistry assays and the like, exhibit decreased non-specific binding to s...  
WO/2011/051950A1
N-substituted 9-aminoacridine and bis-acridino derivatives containing electron- withdrawing groups (EWG) or electron-donating groups (EDG), including amino acid residues, and one-pot methods for their synthesis are disclosed. The derivat...  
WO/2011/034071A1
Disclosed is a process for producing an oxidation reaction product of an aromatic compound, which has excellent environmental load reduction performance, excellent cost reduction performance and the like. Specifically disclosed is a proc...  
WO/2010/151006A1
Provided are a novel organic electroluminescent compound and an organic electroluminescent device using the same. Since the organic electroluminescent compound disclosed herein exhibits good luminescence efficiency and excellent life pro...  
WO/2010/147319A2
The present invention relates to an acridine derivative and to an organic electroluminescent element comprising the same. More specifically, the present invention relates to an acridine derived compound in which an acridine moiety and an...  
WO/2010/145696A1
The present invention relates to methods for detecting presence, or absence, of blood. Specifically, the present invention relates to methods for detecting the presence, or absence, of blood, comprising applying a solution comprising lum...  
WO/2010/147319A3
The present invention relates to an acridine derivative and to an organic electroluminescent element comprising the same. More specifically, the present invention relates to an acridine derived compound in which an acridine moiety and an...  
WO/2010/062107A1
Provided is an electroluminescent device including an organic layer interposed between an anode and a cathode on a substrate, wherein the organic layer includes an electroluminescent layer containing one or more dopant compound(s) of for...  
WO/2010/050779A1
Provided are novel organic electroluminescent compounds, and organic electroluminescent devices and organic solar cells comprising the same. The organic electroluminescent compounds according to the present invention exhibit high luminou...  
WO/2010/045270A2
The invention provides methods and compositions for detecting and measuring the amount of autophagosomes in cells or tissues, including biopsy samples, in vitro, in situ and/or in vivo. By detecting and measuring the amount of autophagos...  
WO/2010/045270A3
The invention provides methods and compositions for detecting and measuring the amount of autophagosomes in cells or tissues, including biopsy samples, in vitro, in situ and/or in vivo. By detecting and measuring the amount of autophagos...  
WO/2009/103798A1
The application relates to cationic compounds of formula (Ia) where R1 to R9 and X- are defined as indicated in claim 1. Said compounds, some of which have not yet been described in the prior art, are suitable for coloring keratinous fib...  
WO/2009/097433A1
There are described novel rhodamine dye compounds and imaging members and imaging methods, including thermal imaging members and imaging methods, utilizing the compounds. The dye compounds exhibit a first color when in the crystalline fo...  
WO/2009/067417A1
A method is provided for N-alkylation of acridine compounds, typically with a 1,3- propane sultone alkylating reagent, in ionic liquid solvents to provide the corresponding acridinium compounds in high yeild.  
WO/2009/041519A1
An organic-inorganic composite material capable of attaining a charge-separated state enhanced in life and stability as compared with that of conventional organic-inorganic composite materials, more particularly, an organic-inorganic com...  
WO/2009/030715A1
The invention relates tosubstitutedarylsulphonylaminomethylphosphonic acid derivativesof general formula (I) wherein the groups Ra to Rf, A and Z are defined as mentioned in the specification and claims, which are suitable for preparinga...  
WO/2009/026858A1
The invention relates to the synthesis and evaluation of novel organic products as anti-parasitic, anti-fungal and anti-viral agents. More specifically, the invention relates to novel derivatives of 10-alyl- (I), 10-(3methyl-2-butenyl)- ...  
WO/2008/124749A1
The present invention relates to methods and kits for detecting an analyte in a test sample using acridinium-9-carboxylate aryl esters.  
WO/2008/109840A1
This invention is directed to, for example, compounds of formula (I): wherein n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically accep...  

Matches 51 - 100 out of 1,215