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Patent Searching and Data


Matches 101 - 150 out of 1,056

Document Document Title
WO/2005/007643A1
The invention relates to novel acridine derivatives of general formula (I), the production and use thereof as medicaments, in particular, for the treatment of tumours.  
WO/2004/099340A1
A luminescent-polymer composition comprising a luminescent polymer and ion pairs, wherein the ion pairs each has an anion having such a specific structure that the anion has one atom of a Group 13 element and is bonded to either an aryl ...  
WO/2004/091485A2
This invention relates to treating inflammatory and immune diseases with certain aminoquinoline compounds that bind to CXCR3 receptors. The aminoquinoline compounds are covered by the formula (I) shown below. Each variable is defined in ...  
WO/2004/092125A2
Substituted alkylmetal reagents such as (trimethylsilylmethyl)lithium are reacted with azaaromatic compounds and/or nitrogen heterocycle compounds to produce functionalized azaaromatic compounds and functionalized nitrogen heterocycle co...  
WO/2004/085418A2
Compound that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods of inhibiting the DNA-PK biological activity, methods of sensitizing cells the agents that cause DNA lesions, and methods of potentiating ...  
WO/2004/078731A1
The invention relates to compounds, substituted guinoline-carboxylic acids and the derivatives thereof of general formula (1, 2, 3), the pharmaceutically acceptable salts thereof, N-oxides or hydrates and methods for the production there...  
WO/2004/069804A1
The invention relates to novel chromogenic enzyme substrates which are used to detect aminopeptidase activity in micro-organisms or to determine whether at least one bacterium belongs to the Gram-positive group or the Gram-negative group...  
WO/2004/067675A2
A blue electroluminescent material based on a binaphtyl compound of the general formula (I). Particular embodiments having the general formula have good solubilities in common organic solvents, resist crystallization and can be sublimed ...  
WO/2004/032929A2
A family of compounds of formula (I) wherein: X is one of the following radicals: (a), (b), (c) which behaves as dual site acetylcholinesterase inhibitors and which are especially useful for the treatment of cognitive disorders as senile...  
WO/2004/020372A1
A fluorene compound represented by the following general formula [I]: is used to provide an organic luminescent device. Such a device has an optical output exhibiting a high luminance with an extremely high efficiency, and has an extreme...  
WO/2004/020373A1
Provided are a novel spiro compound, and an organic luminescence device using the spiro compound and having anoptical output with an extremely high efficiency and a high luminance, and an extremely high durability. The spiro compound is ...  
WO/2004/020371A1
A new condensed polycyclic compound represented by general formula [I]: wherein R¿1? is hydrogen, halogen, cyano, a substituted amino or a group selected from the group consisting of alkyl, aralkyl, aryl, heterocyclic, each having no su...  
WO/2004/018418A2
In accordance with the present invention, it has been discovered that introduction of hydrophilic sulfoalkyl substituents and/or hydrophilic linkers derived from homocysteic acid, cysteic acid, glycine peptides, tetraethylene oxide, and ...  
WO/2004/011946A1
Disclosed are compounds of formula: (I) In which D is a fluorescent dye selected from an acridone and a quinacridone dye; F comprises a target bonding group selected from a carboxylic acid thioester group and a 1,2-aminothiol group; M is...  
WO/2003/082350A2
The present invention is concerned with radiolabelled quinoline and quinolinone derivatives according Formula (I-A)* or (I-B)* showing metabotropic glutamate receptor antagonistic activity, in particular mGlu1 receptor activity, and thei...  
WO/2003/074490A1
The invention relates to pharmaceutical preparations containing a dibenzocyclooctane lignan derivative for prevention and treatment of neurodegenerative disease.  
WO/2003/059269A2
Compounds having formula (I), wherein R?3¿ is selected from H, OH and NH¿2?; R?30¿ is selected from =O and =S; W is -C(=O)-, -S(=O)-, or -S(O)¿2?-; or W may be -CH¿2?- if X is -C(=O)-; X is selected from -CH¿2?-, -N(R?4¿)-, and -O...  
WO/2003/059885A1
This invention pertains to certain acridone and acridine compounds of the formula (1) which inhibit telomerase, regulate cell proliferation, etc., and/or treat cancer, proliferative conditions, etc.: wherein either: (a) K is =O, L is -H,...  
WO/2003/055447A2
Compounds having the formula (I), wherein R?3¿ is selected from H, OH and NH?2¿; R?30¿ is selected from =O and =S; W is -C(=O)-, -S(=O)-, or -S(O)¿2?-; or W may be -CH¿2?- if X is -C(=O)-; X is selected from -CH¿2?-, -N(R?4¿)-, an...  
WO/2003/053934A1
Novel compounds comprising a C-C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating chemiluminescence rapidly by reaction with a...  
WO/2003/053915A2
This invention relates to compounds of the Formula (I):(Chemical formula should be inserted here as it appears on abstract in paper form)(I)or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the tre...  
WO/2003/045920A1
The present invention is concerned with compounds of the general Formula I : and pharmaceutically acceptable salts thereof, which are useful as melanin concentrating hormone receptor antagonists, particularly MCH-1R antagonists. As such,...  
WO/2003/039488A2
The present invention is directed to a method for treating inflammatory bowel disease in a patient comprising administering to said patient a pharmaceutical compositions comprising a pharmaceutically effective amount of an anti-malarial ...  
WO/2003/039546A1
The present invention is directed to the use of anti-malarial compound for the treatment and prophylaxis of infections by adenovirus or rhinovirus.  
WO/2003/037853A1
The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.  
WO/2003/038399A2
A novel chemiluminescent acridinium compound is provided. In one embodiment, the novel compound is employed in an assay to detect analytes. The assay to detect analytes includes the steps of binding the novel compound to the analyte and ...  
WO/2003/035768A1
The present invention relates to squaraine dye containing terminal aminoanthracene or acridine groups and to a process for the preparation thereof.  
WO/2003/027050A2
A process for preparing substituted pentacene compounds comprises the step of cyclizing substituted bis(benzyl)phthalic acids using an acid composition comprising trifluoromethanesulfonic acid, the substituted bis(benzyl)phthalic acids b...  
WO/2003/025192A3
Intracellular enzyme-activated fluorescent substrates that can be transported into a cell are provided. The membrane transportable fluorescent substrates are complexes (e.g., ionic complexes) formed between an enzyme activated fluorescen...  
WO/2003/025017A1
A crystalline composition comprising a crystal of the IL-6 receptor I chain is provided. Also provided are methods of using the crystal and related structural information to screen for and design compounds that interact with IL-6R, or va...  
WO/2003/004091A2
The present invention discloses novel sulfenate derivatives and their bioconjugates for phototherapy of tumors and other lesions. The sulfenates of the present invention are designed to absorb low-energy ultraviolet, visible, or near-inf...  
WO/2002/099097A1
The present invention relates to a chemical compound comprising a light emitting moiety precursor (eg. acridine, luciferine) and a precursor of a leaving group (eg. oxazine, anilide), bound to each other by an amide or by an ester bond a...  
WO/2002/099424A2
Disclosed are new acridone dye derivatives having characteristic fluorescence lifetimes. Also disclosed are methods for labelling target biological materials employing the acridone dyes and use of the labelled materials in biological ass...  
WO/2002/099428A1
The present invention relates to substituted hydrazides of a luciferin dye or to substituted hydrazides of a dye analogous thereto. These chemical compounds comprise the luciferin dye or the dye analogue thereto as a light emitting moiet...  
WO/2002/079166A1
This invention relates to process for producing annulated pyridine bases by reacting cyclic ketones with aliphatic aldehyde in presence of ammonia in gaseous phase in the presence of a catalyst. This process provides an eco-friendly, mor...  
WO/2002/079191A1
Bifunctional molecules based on viologen linked acridines or derivatives thereof, which can be used as phototherapeutical and catalytic photoactivated DNA clevaing agents, a process for the process for the preparation thereof and pharmac...  
WO/2002/067704A1
A smoking article (10) having reduced ignition propensity is disclosed. The smoking article includes a tobacco column (12), a wrapper (14) surrounding the tobacco column (12), and a filter element (16). The wrapper (14) has a base permea...  
WO/2002/064545A1
The present invention relates to acylated indanyl amines according to the general formula (I) where R?1¿-R?4¿ have the meanings given in the description, A is CH¿2? CHOH or CH-(C¿1?-C¿3?-alkyl), B is CH¿2? or CH-(C¿1?-C¿3?-alkyl)...  
WO/2002/059096A1
Synthetic processes and intermediates are disclosed for the preparation of N-arylacridancarboxylic acid derivatives. The derivatives are esters, thioesters, amides and sulfonimides. A key feature of the processes is the preparation of N-...  
WO/2002/055503A1
In accordance with the present invention, nanometer-scale reversable electronic switches are provided that can be assembled to make cross-bar circuits that provide memory, logic, and communications functions. The electronic switches, or ...  
WO/2002/051942A1
The present invention relates to a process for dyeing or printing manufactured natural polymer or synthetic hydrophobic fibre materials, characterized in that it comprises using dyes of the formula (I), where R¿1? is hydrogen, hydroxyl ...  
WO/2002/043449A1
A luminescent element which comprises an anode, a cathode, and a luminescent substance interposed therebetween and which luminesces upon reception of electric energy, characterized by having at least one of the following compounds (a) to...  
WO/2002/036568A1
Compounds useful for the treatment of pain in accord with the following structural diagram, wherein R?1¿, R?2¿, R?3¿, R?4¿ and R?5¿ are any of a number of groups as defined in the specification, A and D are as defined in the specifi...  
WO/2002/032875A1
The invention relates to an agent which inactivates pathogens and to the use thereof. Said agent contains an element that bonds with the nucleic acids of the pathogens and a conjugate, which destroys nucleic acid. The conjugate is produc...  
WO/2002/028837A1
The present invention concerns compounds of formula. In a preferable embodiment, X represents O; R?1¿ represents C¿1-6?alkyl; cycloC¿3-12?alkyl or (cycloC¿3-12?alkyl)C¿1-6?alkyl, wherein one or more hydrogen atoms in a C¿1-6?alkyl-...  
WO/2002/008192A1
The invention relates to novel heteroaryl derivatives of general formula (1), the production thereof and the use of the same as pharmaceuticals, especially for treating tumours.  
WO/2002/008190A2
The invention relates to novel pyridine derivatives of general formula (1), the production and use thereof as medicaments, in particular for the treatment of tumours.  
WO/2002/008194A1
The invention relates to novel acridine derivatives of general formula (1), the production thereof and the use of the same as pharmaceuticals, especially for treating tumours.  
WO/2002/008193A2
The present invention pertains to acridone and acridine compounds of formula (I), wherein either: (a) K is =O, L is -H, alpha is a single bond, beta is a double bond, gamma is a single bond (acridones); or, (b) K is a 9-substituent, L is...  
WO/2002/000726A1
Methods are disclosed for producing electrochemiluminescence by electrochemically oxidizing an acridan compound at an electrode in the presence of a peroxide. Maintaining a sufficiently positive potential results in continuous oxidation ...  

Matches 101 - 150 out of 1,056