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Matches 1 - 50 out of 5,894

Document Document Title
WO/2019/175897A1
The compounds of Formula I is described herein along with their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof. The compounds described herein, their polymorphs, stereoisomers, tau...  
WO/2019/175117A1
The present invention relates to compounds of Formula (I), wherein R1, R2, R3, R4 and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controllin...  
WO/2019/178091A1
Compounds, compositions and methods are provided for the inhibition of GBP1. The subject inhibitor compounds can act by inhibiting GBP1 alone and/or GBP1 : pro-survival kinase (e.g. serine/threonine-protein kinase pim-1 (PIM1 )) interact...  
WO/2019/170745A1
The present invention relates to compounds of Formula (I), wherein R1, R2, R3, R4 and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controllin...  
WO/2019/166270A1
The invention relates to an organic electronic device comprising at least one electron transport, electron injection or electron generation layer comprising a compound of Formula (I) wherein all positions which are not linked to a -(A)a-...  
WO/2019/166269A1
The present invention relates to an organic electronic device comprising, between an anode and a cathode, at least one layer selected from an electron injection layer, an electron transport layer or an electron generation layer, the laye...  
WO/2019/165890A1
Provided herein are chiral compounds that exhibit circularly polarized photoluminescence and electroluminescence and electroluminescent devices and circularly polarized fluorescent probes comprising the same.  
WO/2019/158666A1
The present invention relates to compounds of Formula (I), wherein R1, R2, R3, R4 and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controllin...  
WO/2019/154395A1
Disclosed are a novel tetrahydroisoquinoline compound, a method for preparing intermediates thereof, a pharmaceutical composition thereof and the use thereof. The tetrahydroisoquinoline compound of the present invention has a good inhibi...  
WO/2019/144888A1
The present invention relates to a method for preparing mesaconine and related intermediaries. Specifically, the method for preparing mesaconine of the present invention uses aconitine extracted from the aconitum plant Aconitum soongaric...  
WO/2019/147742A1
A pro-fragrance delivery system based on a vitamin scaffold and a fragrant alcohol. The vitamin scaffold may be a vitamer of vitamin B6 or derivatives thereof. The pro-fragrance releases the fragrant alcohol by action of water at neutral...  
WO/2019/144889A1
The present invention relates to crystalline forms of mesaconine. Specifically, the present invention relates to crystalline form A, crystalline form B, and crystalline form C of mesaconine and a preparation method therefor. The method c...  
WO/2019/148125A1
Provided herein are compounds comprising a three-ring core, such as compounds of Formula (X), Formula (X-A), Formula (X-Ai), Formula (X-B), Formula (X-Bi), Formula (Z), Formula (Z-A), Formula (Z-Ai), Formula (Z-B), Formula (Z-Bi), Formul...  
WO/2019/141673A1
A pharmaceutical composition comprising apomorphine (APO) in a solid crystalline form, wherein the solid crystalline form is an APO·palmitic acid cocrystal solid particle crystalline form.  
WO/2018/111315A8
Disclosed herein are compounds of the formulas: as well as analogs thereof, wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein ...  
WO/2019/132483A1
The present specification relates to a heterocyclic compound represented by chemical formula 1 and an organic light emitting element comprising the same.  
WO/2019/132492A1
The present specification relates to a heterocyclic compound represented by chemical formula 1 and an organic light emitting device comprising the same.  
WO/2019/118855A1
The present invention includes compounds, compositions and methods that are useful for preventing or treating certain types of cancer in a subject. In certain embodiments, the compounds comprise estrogen (including estrogen derivatives o...  
WO/2019/100057A1
The disclosure provides methods of using certain morphinans of Formula (I) that are partial kappa opioid receptor agonists, weak mu opioid receptor agonists, and partial or weak delta opioid receptor agonists in the treatment of kappa op...  
WO/2019/099457A1
Provided herein are benzodioxinone compounds of Formula I that are useful as inhibitors of ACC1 and/or ACC2. The benzodioxinone compounds described herein can be used for treating a disease or disorder associated with aberrant ACC1 and/o...  
WO/2019/100026A1
An electro-polarizable compound has a general formula: (I) Aromatic polycyclic conjugated molecule Core1self-assembles to form supramolecular structures; m donor groups R1 and m' of acceptor groups R1' connect to Core1; m and m' = 0, 1, ...  
WO/2019/094491A1
The present invention relates to a compound of formula (I) including any stereochemically isomeric form thereof, or a pharmaceutically acceptable salt thereof; wherein R1 is -C(=O)O-alkyl, carbonate ester, or -C(=O)-alkyl, ester, or -C(=...  
WO/2019/071355A1
Described are methods and products related to the identification of multiple sclerosis (MS) as a transmissible protein misfolding disorder. Data is presented to support the position that the transmissible protein is an abnormal prion pro...  
WO/2019/062848A1
The present invention discloses an N-(substituted sulfonyl)benzamide derivative, a preparation method therefor, and a pharmaceutical use thereof. Specifically, the present invention discloses an N-(substituted sulfonyl)benzamide derivati...  
WO/2019/054805A1
The present invention relates to a chemically amplified photoresist composition comprising an alkali-soluble resin and a polymeric photoacid generator having a preset structure, to a photoresist pattern generated from the chemically ampl...  
WO/2019/049918A1
The present invention relates to a method of mono-alkylating a piperidine nitrogen in a piperidine derivative with a deuterated lower-alkyl, which comprises protecting the piperidine nitrogen with an aralkyl protective group, lower-alkyl...  
WO/2019/050120A1
The present invention relates to a photoacid generator and a chemically amplified positive photoresist composition for a thick film, comprising the same. The photoacid generator is chemically and thermally stable and can exhibit high sen...  
WO/2019/045377A1
The present invention relates to a photo-acid generator and a chemical amplification type photoresist composition comprising the same for a thick film, wherein the photo-acid generator has, besides effects as a photo-acid generator, rema...  
WO/2019/044736A1
The present invention provides a detection method and detection probe for colibactin and colibactin-producing bacteria. The present invention provides, for example, the detection of myristoyl-asparagine using a tissue sample or stool sam...  
WO/2019/036377A1
The present disclosure provides certain tricyclic compounds that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as cancers an...  
WO/2019/036384A1
The present disclosure provides tricyclic compounds of formula (I) that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as can...  
WO/2019/029613A1
A deuterated quinoline compound, specifically a compound represented by formula (I), a stereochemical isomer thereof, a solvate thereof or a pharmaceutically acceptable salt thereof for use in the preparation of a medicament for treating...  
WO/2019/009412A1
The present invention addresses the problem of providing a novel compound having high LSD1 inhibitory activity, high selectivity for LSD1 inhibition, and/or having useful therapeutic effects for various diseases. One embodiment of the pr...  
WO/2018/236125A1
The present invention relates to a method for converting, into aconine, diester-diterpenoid alkaloids and monoester-diterpenoid alkaloids that are highly toxic substances contained in Aconitum carmichaeli Debeaux or Aconite tuber, and a ...  
WO/2018/201167A3
Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods ...  
WO/2018/212355A1
The fluorescent compound is represented by general formula (I) or (II). In general formulas (I) and (II), R1 and R11 represent an alkyl group or ω-aminoalkyl group; R2 and R12 represent a hydrogen atom or alkyl group; R3 and R13 represe...  
WO/2018/206078A1
The present invention concerns cocrystals of finasteride and a carboxylic acid, a method of their preparation and a pharmaceutical formulation comprising said cocrystals. In addition the invention relates to said cocrystals for use in th...  
WO/2018/191472A1
The presently described technology provides compositions of one or more of oxoacids, polyethylene glycols, and vitamin compounds chemically conjugated to levorphanol ((-)-17-methylmorphinan-3-ol) to form novel prodrugs and compositions o...  
WO/2018/183868A1
The present disclosure relates to compositions and methods for improving the transplantation outcome and/or reducing immune response in a subject. The compositions comprise a DNA-PK inhibitor.  
WO/2018/171684A1
Provided in the present invention are a class of 7H-azulene[1,2,3-i,j]isoquinolin-7-one compounds, a single crystal and a use thereof: a 7H-azulene[1,2,3-i,j]isoquinolin-7-one compound has a structure represented by formula (I), and the ...  
WO/2018/172852A1
The present invention includes novel substituted bicyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and co...  
WO/2018/168818A1
The present invention relates to tetrahydroquinoline derivatives of the present invention or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them an...  
WO/2018/158438A1
The present invention relates to acridine compound of formula structure (I), and to an electron transport layer, which comprises at least one compound of formula (I), an semiconductor layer comprising at least one compound of formula (I)...  
WO/2018/153312A1
Disclosed in the present invention are an azaspiro compound and a preparation method therefor and a use thereof, relating to the field of medicinal chemistry. The azaspiro compound having the structural characteristics of formula (I) of ...  
WO/2018/145550A1
Disclosed is an aza-spirobifluorene derivative characterized by the following structural formula: formula (1), where only one of X1, X2, X3, and X4 is a nitrogen atom while the other three are carbon atoms, R is an aromatic or heteroarom...  
WO/2018/136654A1
Disclosed herein are methods for N-demethylating an N-methylated compound using an enzymatic reaction, rather than, e.g. a chemical modification. Also provided herein are enzymes for performing the reaction.  
WO/2018/136794A1
The present disclosure relates to an optical luminescence dual sensor comprising a polymerized form of a probe for sensing pH; a polymerized form of a probe for sensing oxygen; a polymerized form of an internal reference probe; and a mat...  
WO/2018/128798A1
Novel antagonists of toll-like receptor 4 (TLR-4) are provided. More specifically, the novel antagonists of TLR-4 are derived from morphinan. Further, use of said morphinan derivatives in the treatment of diseases and/or disorders mediat...  
WO/2017/218191A8
The present invention includes compounds, compositions and methods that are useful for preventing or treating melanoma or any other Myc-expressing cancer in a subject. In certain embodiments, the compounds comprise estrogen (including es...  
WO/2018/108064A1
Disclosed are a fourth generation (T790M/C797S mutation) of an EGFR kinase inhibitor, i.e. a spiro-aryl-phosphorous-oxygen compound, in particular a compound as represented by formula (I) and a pharmaceutically acceptable salt thereof, u...  

Matches 1 - 50 out of 5,894