| Document |
Document Title |
|
JPS6396124A |
Anipamil and its salts with physiologically tolerated acids are used for the preparation of drugs having antiarteriosclerotic properties and in the treatment of arteriosclerosis.
|
|
JPS6318575B2 |
Novel substituted 11-amino-undeca-4,8-dienal and 11-amino-undecanal aldehyde-derivatives of the formulae Ia (Ia) or Ib (Ib) +TR in which R1 to R6, Y and m are as defined in patent claim 1, and processes for their preparation are describe...
|
|
JPS6315259B2 |
Novel substituted 11-amino-undeca-4,8-dienal and 11-amino-undecanal aldehyde-derivatives of the formulae Ia (Ia) or Ib (Ib) +TR in which R1 to R6, Y and m are as defined in patent claim 1, and processes for their preparation are describe...
|
|
JPS6312065B2 |
|
|
JPS6312066B2 |
|
|
JPS6330464A |
NEW MATERIAL:An azacycloalkane derivative expressed by formula I (R is alkyl; A and B are -O-, -S- or -NH-; s is 2W7; m and n are 1W15). EXAMPLE: 1-[5-(2-Butylthioethyl)thiopentyl]azacycloheptan-2-one. USE: Useful as an absorption promot...
|
|
JPS6330466A |
NEW MATERIAL:An azacycloalkane compound expressed by formula I (R is alkyl; Y is alkyl, alkoxy, acyloxy, alkylthio, hydroxyl group, carboxyl or 1W12C alkoxycarbonyl; A is -O-, -S- or -NH-; m is 2W7; n is 1W15). EXAMPLE: 5-Methyl-1-(4-Hep...
|
|
JPS6330468A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
|
|
JPS6330465A |
NEW MATERIAL:A cyclic compound expressed by formula I (R is substituted amino; m is 2W7; n is 1W15). EXAMPLE: 1-(4-Heptylaminobutyl)azacycloheptan-2-one. USE: Useful as an absorption promoter, having remarkable enhancing action on penetr...
|
|
JPS62281863A |
A pharmacologically active phenyl-substituted bicyclic lactam has been isolated from the leaves of Clausena lansium. This compound and its derivatives have the formula Where R is hydrogen of a C1-C18-acyl group. It has been found that th...
|
|
JPS62212363A |
NEW MATERIAL:A compound of formula I (R is H, halogen, lower alkyl, lower alkoxy, lower alkylcarbonyl, phenoxy; n is 1W4). EXAMPLE: 1-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinone. USE: An intermediate of medicines. PREPARATION: An amino compo...
|
|
JPS62212372A |
NEW MATERIAL:A compound expressed by formula I [R1 is alkyl, aryl or heteroaryl; R2 is H, halogen, OH, alkyl, alkoxy, alkylthio, CF3, CN, COOH, alkoxycarbonyl, acyloxy or dialkylamino; R3 is H, alkyl, cyloalkyl, alkenyl, hydroxyalkyl, ar...
|
|
JPS6242894B2 |
Novel substituted 11-aminoundecanols of the formula (I) and a process for their preparation are described; in the formula, R1 and R3 independently of one another are hydrogen or alkyl having 1-8 C atoms and R2 and R4 independently of one...
|
|
JPS62169770A |
Benzazecine cpds of the formula (I) and benzoquinoline cpds of the formula (II) are new. R1 and R2 are each independently H or Cl; R3 is H, F, Cl, Br or OCH3; R4 is H, Cl or OCH3, and two or three of R1, R2, R3 and R4 are H; R5 is H, ace...
|
|
JPS62167762A |
Compounds I where R<1> is equal to cycloalkyl, alkenyl, cycloalkenyl, phenyl, where B, C, D and E are equal to methine or nitrogen and B', C', D' and E' are equal to methylene, carbonyl or imino; R<2> is equal to phenyl or phenylalkyl; A...
|
|
JPS62129275A |
A new catalytic process for the isomerization of asocainol isomers at the 6-position which provides an inexpensive, rapid, and simple method for large scale production of the (R,R) isomer of (R,S) asocainol is asocainol. The (R,R) isomer...
|
|
JPS6299333A |
PURPOSE: The titled composition capable of raising endermic permeability of ion dissociating drug even at low voltage and at low electric current, containing a specific compound such as 1-dodecylazacycloheptan-2-one, etc. CONSTITUTION: T...
|
|
JPS6245573A |
The present invention relates to the use of lactam amides of the formula I in which n represents 3 to 6, A represents a direct bond or an optionally substituted alkylene bridge, R<1> represents optionally substituted aryl, R<2> represent...
|
|
JPS61257973A |
NEW MATERIAL:A compound shown by the formula I [R1 and R2 are H or organic residue bonded through C or SO2; X is group shown by the formula II W formula V (R4 is H, OH, halogen, etc.; R5 is bifunctional group bonded through two carbons; ...
|
|
JPS61251670A |
NEW MATERIAL:The antibiotic substance 83-16b,c of formula I (R is isovaleryl or 2-methylbutyryl) or its salt. EXAMPLE: The antibiotic substance 83-16b of formula II. USE: Medicine. Carcinostatic agent. It has no antibacterial activity to...
|
|
JPS61236767A |
The present invention relates to the compound naphthomycin H of the formula I and to a microbiological process for its preparation. The compound is active against Gram-positive bacteria and fungi and can be used as an antibiotic.
|
|
JPS61172859A |
A process for the preparation of Schiff's bases which contain amino groups, of the formula wherein n is 3 to 12, by reacting cyclic lactams of the formula wherein n is 3 to 12, or of their ring-opened polymers of the formula wherein n is...
|
|
JPS61151168A |
The invention relates to the N-substituted acyl-lactam compound of the formula:where-R' is a bivalent cyclic or non-cyclic alkyl, aralkyl, alkaryl or aryl radical- R" a bivalent radical having the following general formulawherein- R'" is...
|
|
JPS61134375A |
NEW MATERIAL:L- or D-α-t-Butoxycarbonylamino--caprolactam shown by the formula. USE: Useful as a raw material for optically active N2-t-butoxycarbonyllysine suitable for peptide synthesis. PREPARATION: For example, DL-α-amino--caprolac...
|
|
JPS6118552B2 |
|
|
JPS6118765A |
Benzofused lactams and salts thereof. Said new substances are antagonists of cholecystokinin. They are used as active ingredient in pharmaceutical compositions which are useful for treating gastrointestinal disorders, central nervous sys...
|
|
JPS6115874A |
Compounds of the formula: wherein R<1> is, e.g., hydrogen or hydrocarbon of from 1 to 12 carbon atoms; R<2> is, e.g., hydroxy; loweralkoxy; amino; loweralkylamino or diloweralkylamino; m is 1-3; R<3> is loweralkyl or substituted loweralk...
|
|
JPS6115875A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
|
|
JPS60255771A |
A process for the preparation of racemic asocainol in the (R,R; S,S)-form and (-)-asocainol in the (S,S)-form as well as the pharmacologically compatible salts thereof is herein described on the basis of a thermal rearrangement of the in...
|
|
JPS60197657A |
This disclosure describes platinum chelates of 2- hydrazino-1-aza(or 1,3-diaza)-1-cyclo-alkenes which possess activity as antitumor agents.
|
|
JPS60184064A |
NEW MATERIAL:A phthalimide derivative shown by the formula I [R is H, or alkyl; ring A of broken line is group shown by the formula IVWVI; R1, R2, R4 and R5 are H, alkyl, or R1 and R2 or R4 and R5 are bonded to form a part of a ring of 3...
|
|
JPS6037092B2 |
This invention relates to compositions for carrying physiologically active agents through body membranes. Many physiologically active agents are best applied topically to obtain desirable results. The greatest problem in applying physiol...
|
|
JPS6032634B2 |
The invention relates to a novel process for preparing 2-guanidinomethyl-perhydroazocine-sulfate of formula I I comprising the steps of catalytically reducing the 2-nitromethylene-perhydroazocine of formula IV IV in solution in acetone a...
|
|
JPS60123467A |
PURPOSE: To produce an acyllactamcarboxylic acid which is an anionic polymerization accelerator for lactams in high purity and yield, by facilitating the reaction of a metal salt of a lactam with a cyclic acid anhydride. CONSTITUTION: A ...
|
|
JPS60115565A |
New compounds of the formula
|
|
JPS6023100B2 |
A procedure to prepare 1-aryloxy-4-amino-2-butanoles effective against cardiac arrhythmias, which have the formula ArO-CH2-CHOH-CH2-CH2-NR1R2 wherein: Ar is selected from the group consisting of 1-naphthyl, 2-naphthyl, inden-4 (or 5-) yl...
|
|
JPS6021993B2 |
|
|
JPS6017782B2 |
PURPOSE:N<2>-Arylsulfonyl-L-arginingmides and their salts expressed by the formula I: [R is-NR1(CH2)nCOOR2 (R1 is alkyl, etc.; R2 is H, alkyl, etc.; n is 1,2 or 3), the formula II: (R3 is H, aralkyl, etc.; R4 is alkyl, etc.; R5 is H, ary...
|
|
JPS6016943B2 |
|
|
JPS6016944B2 |
|
|
JPS6015621B2 |
|
|
JPS6010027B2 |
|
|
JPS6010026B2 |
|
|
JPS604168B2 |
1421058 Dibenzocycloheptenyl lactamimides RICHARDSON-MERRELL Inc 28 Nov 1973 [5 Jan 1973] 55212/73 Heading C2C Novel compounds of the Formula (I): wherein n is an integer of from 3 to 11, and pharmaceutically acceptable acid addition sal...
|
|
JPS608260A |
This invention provides for certain lactam derivatives, their pharmaceutical formulations, and a method of treating hypertension.
|
|
JPS5984869A |
Compounds of the formula: wherein: R<1> is, e.g., hydrogen or alkyl of from 1 to 12 carbon atoms; R<2> and R<4> are independently, e.g., hydroxy or loweralkoxy; m is 1-4; R<3> is where n is 2-5; provided that where n = 3 or 4, the carbon...
|
|
JPS5919102B2 |
|
|
JPS5913505B2 |
|
|
JPS5913504B2 |
|
|
JPS5913506B2 |
|
