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Matches 1 - 50 out of 420

Document Document Title
WO/2017/118174A1
The present invention discloses an organic functional compound for preparing an organic electronic device and an application thereof. The organic functional compound has a general formula (I). The organic functional compound comprises an...  
WO/2017/055885A1
The invention relates to processes for the production of compounds of the general formula (I): wherein R1 is hydrogen atom, a linear or branched alkyl group having 1 to 4 carbon atoms, or phenyl group; and R2 is, independently of R1, a l...  
WO/2016/153054A1
Provided are an efficient method for producing a nitrogen-containing compound or salt thereof to be used in the production of a treatment agent for diseases involving an integrin. Also provided is a production intermediate of the same. A...  
WO/2015/100609A1
Provided are new biphenyl derivatives of formula (Ia). These compounds act as aromatase and sulfatase inhibitors. They are particularly useful for treating pathological conditions or diseases in which aromatase and sulfatase are involved...  
WO/2015/046916A1
The present invention relates to a specific combination of dopant compounds and host compounds. By using a combination of the dopant and host compounds according to the present invention, an organic electroluminescent device has improved...  
WO/2014/201073A1
The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.  
WO/2014/201073A9
The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.  
WO/2014/177689A1
The present invention relates to a method of labelling biological molecules with 18F, via attachment of fluorine to a metal complex, where the metal complex is conjugated to the biological molecule. The invention highlights the incorpora...  
WO/2014/157207A1
Provided is a room-temperature phosphorescent material which is responsive to external stimuli. A luminescent metal complex responsive to external stimuli according to the present invention is represented by general formula (I) (wherein ...  
WO/2014/111639A1
The invention relates to amphiphilic derivatives of a triazamacrocyclic compound, as well as to said derivatives as active molecule transporters. The invention also relates to a nanodrug including at least one amphiphilic derivative of a...  
WO/2014/111661A1
The invention relates to complexing agents of formula (I) where A, chrom1, chrom2 and chrom3 are such as defined in the description. The invention also relates to lanthanide complexes resulting from said complexing agents.  
WO/2014/079953A1
The present invention relates to a compound with formula (V'). The invention also relates to the synthesis method for compound (V') and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivati...  
WO/2014/040709A1
The present invention relates to a compound of formula (1) wherein X1 represents O or NR6, X2 represents O or NR6, X3 represents O or NR1, R1 represents H or C1 to C3 alkyl, R2 represents H, or a linear or branched C1 - C8 alkyl optional...  
WO/2013/116682A1
The invention relates generally to macrocyclic compounds of formula I and their therapeutic use. More particularly, the invention relates to macrocyclic compounds that modulate the activity of IL-17 and/or are useful in the treatment of ...  
WO/2013/090454A3
The invention relates to compounds that are characterized by possessing at least four cycles (A-C and phenylene ring). Such compounds modulate the glucagon-like peptide 1 (GLP-1) receptor and have a therapeutic use that includes diseases...  
WO/2013/090454A2
The invention relates to compounds that modulate the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds are act as modulators or potentiators of ...  
WO/2013/086396A1
Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation me...  
WO/2013/065725A1
The present invention relates to a phthalamide derivative represented by general formula (I) or a salt thereof. [In the formula, X1 represents a halogen atom or the like; X2 represents a halogen atom or the like; m represents 0, 1, 2 or ...  
WO/2012/175666A1
Compounds of formula (I) wherein the substituents are as defined in claim 1, are useful as a pesticides and herbicides.  
WO/2012/158707A1
Presently disclosed are methods and compositions for treating or preventing WHIM syndrome and certain other disorders or conditions with a certain CXCR4 antagonist.  
WO/2012/105814A2
The present invention relates to a triazanonane derivative indicated by the chemical formula 1 below, or a pharmaceutically acceptable salt thereof, and a method for preparing same, and the triazanonane derivative according to the presen...  
WO/2012/105814A3
The present invention relates to a triazanonane derivative indicated by the chemical formula 1 below, or a pharmaceutically acceptable salt thereof, and a method for preparing same, and the triazanonane derivative according to the presen...  
WO/2012/082618A3
The present application discloses compositions and methods of synthesis and use of 18F or 19F-labeled molecules of use in PET, SPECT and/or MR imaging. Preferably, the 18F or 19F is conjugated to a targeting molecule by formation of a co...  
WO/2012/020742A1
Disclosed is a novel compound that acts as an antagonist for P2X3 and/or P2X2/3 receptors. Also disclosed is a pharmaceutical composition that acts as an antagonist for P2X3 and/or P2X2/3 receptors, said composition containing: a compoun...  
WO/2012/003598A1
The present invention provides intermediates for the synthesis of 1,2-bis(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)-ethane and preparation method thereof. The intermediates are protonated salts of 1,4-ditosylate-1,4,7-triazacyclononane or ...  
WO/2012/003599A1
The present invention provides an improved process to synthesize bis(triazacyclononane) ligands, in which 1,4-di(arylsulfonate)-1,4,7-triazacyclononane is reacted with dihaloethane to produce 1,2-bis(4,7-diarylsulfonate-1,4,7-triazacyclo...  
WO/2012/003712A1
The present invention provides improved processes for the synthesis of 1,4-ditosyl- 1,4,7-triazacyclonone and protected analogues thereof, and to synthesise bis(triazacyclononane) ligands.  
WO/2011/115802A1
Conjugates of 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropanes with a variety of conjugating members are used in the formation of dinuclear metal complexes which bind to phosphate esters. By virtue of their conjugated forms, the comp...  
WO/2011/111971A3
The present invention relates to a method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2-4-triazin-4(1H)- yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are oxazolidinone antibiotic compounds having a cyc...  
WO/2011/111971A2
The present invention relates to a method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2-4-triazin-4(1H)- yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are oxazolidinone antibiotic compounds having a cyc...  
WO/2011/100838A8
Compounds of formula (I) wherein m, R1, R2, R3, X and Y are defined herein, are useful as inhibitors of HIV replication.  
WO/2011/100838A1
Compounds of formula (I) wherein m, R1, R2, R3, X and Y are defined herein, are useful as inhibitors of HIV replication.  
WO/2011/100838A9
Compounds of formula (I) wherein m, R1, R2, R3, X and Y are defined herein, are useful as inhibitors of HIV replication.  
WO/2010/114308A1
The present invention relates to novel amino acid derivatives containing heterocyclic chelating residues thereof; radioactive or nonradioactive metal complexes thereof; methods for preparation thereof; and apyrogenic and sterile preparat...  
WO/2010/103204A1
The invention relates to compounds that can be used as metal ion chelating agents or as pollution control agents, having general formula (I), to precursor compounds having formula (II) and to labeled compounds having formula (III). The p...  
WO/2010/066051A1
A thiol-NOTA derivative of Formula (I): wherein n is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10; and m is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10 is described herein. The thiol-NOTA derivatives are suitable for kit 68Ga radiolabeling of proteins and peptides.  
WO/2010/056496A1
The present invention relates to a compound represented by formula (I): wherein R1 represents a hydrogen atom or the like; R2 and R3 represent a hydrogen atom or the like; R4 is a group represented by (II) R5 represents a phenyl group wh...  
WO/2010/055207A1
This invention relates to a group of chelating agents, novel chelates, biomolecules labeled with these chelates or chelating agents as well as solid supports conjugated with these chelates, chelating agents and labeled biomolecules. The ...  
WO/2010/011367A3
Substituted l,4,7-triazacyclononane-N,N',N"-triacetic acid and 1,4,7,10- tetraazacyclcododecane-N,N',N",N'"-tetraacetic acid compounds with a pendant amino or hydroxyl group, metal complexes thereof, compositions thereof, and methods of ...  
WO/2009/115644A1
This invention relates to luminescent lanthanide(III) chelates based on β-diketones comprising an azacycloalkane backbone and biomolecule conjugates and solid supports comprising these chelates. In contrast to lanthanide chelates based ...  
WO/2009/113148A1
The invention relates to a novel iron complex bearing a cyclic amine as ligand; and a process for the production of polymers by polymerizing a radical-polymerizable monomer in the presence of the iron complex and a radical generator. The...  
WO/2009/113033A3
The present invention relates to linear and cyclic guanidine derivatives, method of preparation and uses thereof, pharmaceutical compositions to be used as antifungal agents, in particular against Candida species.  
WO/2009/113033A2
The present invention relates to linear and cyclic guanidine derivatives, method of preparation and uses thereof, pharmaceutical compositions to be used as antifungal agents, in particular against Candida species.  
WO/2009/069833A1
A core of a cyclic structure represented by (-N-(CH2)n-)k is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal...  
WO/2009/038752A3
This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for b...  
WO/2009/038752A2
This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for b...  
WO/2009/014730A1
Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the t...  
WO/2008/123779A1
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds ...  
WO/2008/114864A1
Disclosed is a divalent iron complex wherein a cyclic amine compound represented by the general formula (2) below is coordinated to an iron compound represented by the general formula (1) below. Also disclosed is a method for producing a...  
WO/2008/096001A8
Compounds of the Formula (I) including a stereoisomer thereof, or an N-oxide, a pharmaceutically acceptable addition salt, or a pharmaceutically acceptable addition solvate thereof;usefulas HCV inhibitors; processes for preparing these c...  

Matches 1 - 50 out of 420