Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 701 - 750 out of 6,616

Document Document Title
WO/2008/130319A3
The present invention relates to new compounds and to pharmaceutical composition containing said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compou...  
WO/2008/034039A3
The present invention provides a compound selected from compounds of formula (A) as ligand binding to the HDM2 protein, inducing apoptosis and inhibiting proliferation, and having therapeutic utility in cancer therapy and prevention. Com...  
WO/2008/073138A3
Described herein are compounds having a terephthalamate structural feature. Also described herein, are methods of making such compounds, methods of using such compounds to modulate the activity of HIV integrase, and pharmaceutical compos...  
WO/2008/149380A2
This invention relates to a process for solvent less synthesis of benzoxazine which comprises in taking a phenol in molar combination with primary amine and aldehyde so as to form a ring of oxazine, heating said reactants to a temperatur...  
WO/2008/145526A1
Polymerizable combinations, comprising at least one first component selected from the group of benzoxazine monomers and at least one second component selected from the group of aromatic esters are described. Furtheron the use of aromatic...  
WO/2007/146122A3
Tetrahydropyrido[3,4-d]pyrimidines and related analogues are provided, of the formula (I) in which variables are as described herein, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand b...  
WO/2007/136790A3
Intracellular kinase inhibitors and their therapeutic uses for patients with T cell malignancies, B cell malignancies, autoimmune disorders, and transplanted organs.  
WO/2005/025498A3
Substituted acetanilide or benzamide compositions or formulations for delivery by aerosolization are described. The formulation contains an efficacious amount of acetanilide or benzamide compound able to inhibit inflammation in asthmatic...  
WO/2008/140859A1
Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disor...  
WO/2008/109463A3
The compositions described herein shift the light output of luciferases to the near-IR by resonance energy transfer to a targetable near-IR fluorophore.  
WO/2008/119685A3
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof. The compounds or salts modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor. The...  
WO/2008/133273A1
Disclosed is a pharmaceutical composition for treatment of Alzheimer's disease, which contains a compound represented by the formula (I) below, a pharmaceutically acceptable salt thereof, or a solvate of any of them as an active ingredie...  
WO/2008/129004A2
Herein are described heterocyclic compounds containing the morpholine nucleus prepared from amino acids, their preparation and use for therapeutic applications.  
WO/2008/130616A2
The present invention provides compounds having the general structure of Formula (I) or a pharmaceutically acceptable salt, solvate, ester or prodrug thereof, which are useful as CB1 receptor antagonists. The compounds of the invention m...  
WO/2008/131259A1
This disclosure relates to novel deuterated morpholinyl compounds and their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosu...  
WO/2007/046022A3
The present invention relates to oxazine derivatives, which can be used as selective inhibitors of phosphodiesterase (PDE) type IV. Compounds disclosed herein can be useful in the treatment of CMS disorders, AIDS, asthma, arthritis, bron...  
WO/2007/075852A3
The present invention provides novel calcium channel antagonists, and methods of treating disease sates using the novel antagonists.  
WO/2008/125342A2
The present invention relates to novel vanilloid receptor ligands, a method for the production thereof, pharmaceuticals containing said compounds, and the use of said compounds for the production of pharmaceuticals.  
WO/2008/123017A1
Disclosed is a novel compound having a strong FXa inhibitory activity and exhibits quick, sufficient and lasting antithrombotic effect even by oral administration. Specifically disclosed is a compound represented by the general formula (...  
WO/2008/077647A3
The invention relates to non-steroidal progesterone receptor modulators of general formula (I), use of the progesterone receptor modulators for the production of medicaments and pharmaceutical compositions containing said compounds. Said...  
WO/2008/120093A1
The invention is directed to a class of compounds, including the pharmaceutically acceptable salts of the compounds, having the structure of formula (I), as defined in the specification. The invention is also directed to compositions con...  
WO/2008/090193A3
The invention relates to a method for producing betamimetics of formula (1), wherein in which n represents 1 or 2; R1 represents hydrogen, halogen, C1-4-alkyl or O-C1-4-alkyl; R2 represents hydrogen, halogen, C1-4-alkyl or O-C1-4-alkyl a...  
WO/2008/119457A2
The invention relates to novel lactam-substituted dicarboxylic acid derivatives, to methods for producing the same, and to their use in the treatment and/or prophylaxis of diseases. The invention also relates to the use of said substance...  
WO/2008/119685A2
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof. The compounds or salts modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor. The...  
WO/2007/120511A3
Methods of synthesizing ammonia borane are provided. The methods comprise reacting at least one amine borane with ammonia such that ammonia borane is produced. Ammonia borane has a chemical formula Of NH3-BH3 and provides a good source o...  
WO/2008/115804A1
Novel indolearaine 2, 3-dioxygenase (IDO) inhibitors, compositions comprising the same, and methods of use thereof are disclosed.  
WO/2008/111300A1
Disclosed is a novel compound which has a potent FXa inhibition activity and exhibits a sufficient and sustained antithrombotic effect rapidly when administered orally. Specifically disclosed is: a compound represented by the general for...  
WO/2008/111668A1
Disclosed is an excellent prophylactic and/or therapeutic agent for neurogenic pain, which comprises a 2-[(substituted-indene-7-yloxy)methyl]morpholine represented by the formula (I) or a pharmaceutically acceptable salt thereof as an ac...  
WO/2008/110466A1
This invention relates to overcharge protection and molecular redox shuttles in rechargeable lithium-ion cells. For this, specific nitroxyls or oxoammonium salts are used in the electrolyte. This invention also relates to a method of pro...  
WO/2008/111669A1
Disclosed is an excellent prophylactic and/or therapeutic agent for diabetic neuropathy, which comprises a 2-[(substituted-indene-7-yloxy)methyl]morpholine represented by the formula (I) or a pharmaceutically acceptable salt thereof as a...  
WO/2008/108630A1
The present invention provides novel crystalline forms of Efavirenz, designated Efavirenz form ULT-I and ULT-2 respectively, methods for the preparation of Efavirenz form ULT-I and ULT-2 respectively and the use of Efavirenz form ULT-I a...  
WO/2008/106128A2
This invention relates to novel compounds of the Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation o...  
WO/2008/042755A3
Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheim...  
WO/2008/059513A3
Disclosed herein in the embodiments of the present invention are the compounds suitable as modulators of HDL having general formula (1), novel intermediates involved in their synthesis, their pharmaceutically acceptable salts and pharmac...  
WO2007037898A8
This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variant...  
WO2008053393A8
Electromechanical rotary actuator (52) for moving shutters (13) of gates or doors, comprising a motor enclosed in a casing (50), a rotating arm (56) connected to the motor for moving the shutter or swinging door, a movable catcher (72) f...  
WO/2008/063794A3
Oxazolidinium compounds are formed by the reaction of a halohydrin or an epoxide with a secondary amine and an aldehyde or a ketone. The oxazolidinium compounds are formed directly and do not require the reaction of a pre-formed oxazolid...  
WO/2008/094496A1
A method of detecting platinum group metals in a sample is provided. The method comprises the step of contacting the sample with a fluorophore capable of undergoing allylic ether or allylic ester cleavage. The fluorophore has an oxygen-p...  
WO/2008/042896A3
Disclosed are nordihydroguaiaretic acid derivative compounds including various end groups bonded by a carbon atom or heteroatom though a side chain bonded to the respective hydroxy residue O groups by an ether bond or a carbamate bond, p...  
WO/2008/090193A2
The invention relates to a method for producing betamimetics of formula (1), wherein in which n represents 1 or 2; R1 represents hydrogen, halogen, C1-4-alkyl or O-C1-4-alkyl; R2 represents hydrogen, halogen, C1-4-alkyl or O-C1-4-alkyl a...  
WO/2007/035425A3
Certain cyclopropyl amines are histamine H3 modulators useful in the treatment of histamine H3 receptor mediated diseases.  
WO/2007/092961A3
This invention provides compositions which are l,3-oxazinan-2-one compounds of formulae (I) and (II), and oxazolidinone compounds of formula (III): wherein R is a hydrocarbyl group, a heterocyclic group, a hydrocarbyl group having at lea...  
WO/2008/053393A3
Electromechanical rotary actuator (52) for moving shutters (13) of gates or doors, comprising a motor enclosed in a casing (50), a rotating arm (56) connected to the motor for moving the shutter or swinging door, a movable catcher (72) f...  
WO/2008/077647A2
The invention relates to non-steroidal progesterone receptor modulators of general formula (I), use of the progesterone receptor modulators for the production of medicaments and pharmaceutical compositions containing said compounds. Said...  
WO/2008/077646A1
The invention relates to non-steroidal progesterone receptor modulators of general formula (I), use of the progesterone receptor modulators for the production of medicaments and pharmaceutical compositions containing said compounds. Said...  
WO/2008/079339A2
The present invention pertains, at least in part, to a substituted tetracycline compound of Formula (I): wherein X is CHC(R13VY), CR6 R6, C=CR6 R6, S, NR6, or O; E is NR7dR7β, OR7f or (CH2)o.iC(=W)WR7s; W is O, S, NR711 or CR75R7*; W is...  
WO/2008/076754A2
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).  
WO/2008/075025A1
The present invention provides compounds of formula (I), wherein k, Ar, R2, R3, R4, R5, R4', R5', R6, R7, A, D, m and E are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and...  
WO/2008/052075A3
Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided, wherein each of Z, X, R1, R2, R3, R4, y, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists...  
WO/2008/072850A1
The present invention relates to a novel triazine derivative or a pharmaceutically acceptable salt thereof, and an Acetyl-CoA Carboxylase (ACC) comprising same as an active ingredient. The triazine derivative of the present invention eff...  

Matches 701 - 750 out of 6,616