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Matches 1 - 50 out of 6,393

Document Document Title
WO/2018/219882A1
The invention relates to a borated benzoxazine compound, particularly for use as a monomer for the synthesis of polybenzoxazine, said borated benzoxazine compound being of formula (A), in which: Z is an at least divalent, aliphatic, cycl...  
WO/2018/215701A1
The invention relates to a halogenated benzoxazine compound, for use particularly as a monomer for the synthesis of polybenzoxazine, said halogenated benzoxazine compound being of formula (A) in which: each benzene ring of the two oxazin...  
WO/2018/215700A1
The invention relates to a halogenated benzoxazine compound, for use in particular as a monomer for the synthesis of polybenzoxazine, said halogenated benzoxazine compound being of formula (A) (the symbol Hal representing at least one ha...  
WO/2018/209445A1
There is described compounds, compositions, methods, and uses, of treating a subject having, suspected or having, or at risk of having, a prion disease, comprising: administering a cholesterol 24-hydroxylase (CH24OH)-activating compound.  
WO/2018/198975A1
Provided is a light-emitting element having excellent luminance life. Disclosed is a light-emitting element comprising a positive electrode, a negative electrode, a first organic layer provided between the positive electrode and the nega...  
WO/2018/173058A1
The present invention provides processes for the preparation of diverse heterocyclic scaffolds from alpha-enaminone building bloc of formula (I).  
WO/2018/174826A1
This invention relates to a method for producing an alkenyl 1 -aminocyclopropane-1 -carboxylic acid of Formula I wherein R1 is a protecting group, n is an integer between 1 and 10, and A and B are chiral centres such that when A is S, B ...  
WO/2018/167800A1
The present invention relates to fused bicyclic compounds that are inhibitors of GPR91, their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions containing them. T...  
WO/2018/159834A1
Provided are a donor-acceptor type compound having a novel structure and an application of the donor-acceptor type compound. This enamine compound is represented by general formula (1) (in the formula: R1 represents an electron-accepting...  
WO/2018/154414A1
This invention relates to a method for the manufacture of optically pure (S)-6- chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)- 2H-3,1 -benzoxazin- 2-one. Specifically, this invention relates to a flow synthesis method for t...  
WO/2018/149370A1
Disclosed are a fluorenylaminoketone photoinitiator, a preparation method thereof and a UV photocurable composition containing same. The photoinitiator comprises a compound having a structure as shown in general formula (I) or a derivati...  
WO/2018/138362A1
The present invention provides e.g. N-{[2-(piperidin-1-yl)phenyl] (phenyl)methyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl) acetamide derivatives and related compounds as ROR-gamma modulators for treating e.g. autoimmune diseases, aut...  
WO/2018/133859A1
Disclosed herein are compounds and methods for using the same for the detection of hydrogen peroxide in situ. The compounds can include compounds of Formula (I), Formula (II), or Formula (III), or a salt thereof, wherein X1 is a monovale...  
WO/2018/136890A1
The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLR...  
WO/2018/129411A1
Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases o...  
WO/2018/126072A1
The present invention provides polycyclic oxothioxoimidazolidines, dioxoimidazolines, oxothioxooxazolidines, dioxooxazolidines, and related compounds, which are useful as integrin agonists. Methods for the treatment of integrin-mediated ...  
WO/2018/115096A1
The present invention relates to a new process for producing 2-(3-(4-propylheptyl)morpholino)ethan-1-ol with the INN name Delmopinol. The invention also relates to three key intermediates 1-chloro-4- propylhept-3-ene, 1-iodo-4-propylhept...  
WO/2018/115111A1
The present invention relates to a method for the manufacture of 2-(3-(alkyl or alkenyl)morpholino)-ethan-1-ols by reduction of 8a-(alkyl and alkenyl)hexahydrooxazolo[2,3-c][1,4]oxazines encompassing a process for producing 2-(3-(4-propy...  
WO/2018/115116A1
The present invention relates to a new process for producing intermediates useful in the manufacture of 2-(3-(4-propylheptyl)morpholino)ethan-l-ol. The invention also relates to intermediates l-chloro-4-propylhept-3-ene and l-iodo-4-prop...  
WO/2018/114887A1
The present invention provides an improved process for the manufacture (R)-6- hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethyl-eth ylamino-ethyl]-2H-1,4- benzoxazin-3(4H)-one, in high purity and high yield, through the use of 1,1...  
WO/2018/111619A1
Pharmaceutical compositions for treating or mitigating glaucoma are described, the compositions comprising several separate components for an improved effect. Methods for fabricating the compositions and using them are also described.  
WO/2018/112081A1
The present disclosure provides a class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: (insert Formula I structure) wherein variables W, X, Y, R2, R2', R3, R4, R5,...  
WO/2018/106825A1
Disclosed herein are salts and polylmoprhs of (2S)-2-[(S)-(ethoxyphenoxy)phenylmethyl]morpholine (esreboxetine) as shown in Formula I, wherein an acid is selected from adipic, L-ascorbic, L-aspartic, fumaric, glycolic, hydrochloric, male...  
WO/2018/101329A1
The purpose of the present invention is to develop a therapeutic agent for inflammatory diseases such as inflammatory bowel disease and NASH, said therapeutic agent having few adverse effects and high efficacy. The present invention prov...  
WO/2018/102419A1
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.  
WO/2018/095488A1
The invention relates to sulfobetaine compounds, a process for synthesizing same, and the uses of sulfobetaine compounds for synthesizing antimicrobial materials, antistatic materials, antifouling materials, printing inks, surface-active...  
WO/2018/069842A1
This invention relates to 4-substituted phenylamine derivatives of the general formula (I), wherein R1 to R8 and A have the meanings as defined in description. The invention further relates to methods for their preparation and use of sai...  
WO/2018/069841A1
This invention relates to 4-substituted phenylamine derivatives of the general formula (I), wherein R1 to R9 and A have the meanings as defined in description. The invention further relates to methods for their preparation and use of sai...  
WO/2018/065768A1
The present invention relates to cyano-substituted-heterocycles of Formula (I) with activity as inhibitors of deubiquitilating enzymes, in particular, ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30), having u...  
WO/2018/057430A1
Amine substituted morpholino oligonucleotides, other than the classical N,N-dimethylamino PMO analogue, and methods of efficiently synthesizing these oligonucleotides with high yield are provided. Morpholino oligonucleotides having thiop...  
WO/2018/057134A1
The present invention relates to an unsaturated fluorinated ether or amine compound of formula (I) with low global warming potential and method of making the compound (I), where RH 1 is and RH 2 are independently selected from H or CH3, ...  
WO/2018/051278A3
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051278A4
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051930A1
The purpose of the present invention is to provide: a composition for forming a resist lower-layer film that allows the formation of a resist lower-layer film with outstanding flatness and outstanding solvent resistance and etching resis...  
WO/2018/051278A2
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/048261A1
The present invention relates to a novel spiroquinone derivative compound, a production method thereof, and a pharmaceutical composition for preventing or treating neurological disorders which contains the compound as an active ingredien...  
WO/2018/044896A1
Chemical entities of Formula (I): Including enantiomers thereof, wherein R1 has any of the values described herein, and compositions comprising such chemical entities; their preparation; and their use in various methods, including the tr...  
WO/2018/039096A1
A composition includes a perfluorinated propenylamine represented by the following general formula (1): Each occurrence of Rf1 and Rf2 is: (i) independently a linear or branched perfluoroalkyl group having 1-8 carbon atoms and optionally...  
WO/2018/030550A1
The present invention relates to a compound that may have an ROR(gamma)t modulating activity and can thus be useful in the treatment of cancer.  
WO/2018/017490A1
The present invention relates to novel sulfonamide derivatives, to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to methods of using them for controlling the growth of plants, ...  
WO/2018/011676A1
Provided herein are novel, commercially viable and industrially advantageous processes for the preparation of 2-hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one, and its intermediates, in high yield and purity.  
WO/2018/007217A1
The present invention relates to novel sulfonamide derivatives, to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to methods of using them for controlling the growth of plants, ...  
WO/2018/009256A1
The present invention relates to ampakines, including low impact ampakines, and pharmaceutical compositions and methods employing ampakines for treating central nervous system (CNS) disorders, including attention deficit disorders. Novel...  
WO/2018/004289A2
The present invention relates to a benzoxazine-based mixture and a use thereof and, more specifically, to a benzoxazine-based mixture and a use of a cured product in which the benzoxazine-based mixture is cured, wherein the benzoxazine-b...  
WO/2018/004066A1
The present invention relates to an aryl ethane derivative, for inhibiting an estrogen-related receptor gamma (ERRγ) activity, a prodrug of same, a solvate of same, a stereoisomer of same or pharmaceutically acceptable salts of same, an...  
WO/2018/004289A3
The present invention relates to a benzoxazine-based mixture and a use thereof and, more specifically, to a benzoxazine-based mixture and a use of a cured product in which the benzoxazine-based mixture is cured, wherein the benzoxazine-b...  
WO/2018/004065A1
The present invention relates to an aryl ethane derivative, for inhibiting an estrogen-related receptor gamma (ERRγ) activity, a prodrug of same, a solvate of same, a stereoisomer of same or pharmaceutically acceptable salts of same, an...  
WO/2017/216299A1
The object of the present invention are compounds comprising at least one donor group and at least one acceptor group, as described herein, which are characterized by a pronounced CT character. The invention also relates to the use there...  
WO/2017/215549A1
Disclosed are an organic electroluminescent compound and an application thereof. The structural formula of the compound is as shown in general formula (1). The material has good fluorescence quantum efficiency and electroluminescence eff...  
WO/2017/205425A1
Described herein are molecules for use in organic light emitting diodes comprising at least one moiety A, at least one moiety D, and at least one moiety B.  

Matches 1 - 50 out of 6,393