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Matches 1 - 50 out of 4,504

Document Document Title
WO/2019/171234A1
The present invention relates to novel heterocyclic compound of Formula (I), (I) wherein, Het, L1, A, L2 and R12 are as defined in the detailed description, for use as fungicides.  
WO/2019/166206A1
The present invention relates to an organic material and to an electronic device comprising the organic material, particularly to an electroluminescent device, particularly to an organic light emitting diode (OLED), wherein the semicondu...  
WO/2019/162309A1
The present invention relates to benzamide compounds of formula I (I) wherein the variables are defined as in the claims and the description, the N-oxides and salts thereof,and to compositions comprising the same. The invention also rela...  
WO/2019/154416A1
The present disclosure provides a compound of Formula (I); or a pharmaceutically acceptable salt thereof, wherein R1 and R2 manufacturing the compounds of the disclosure, and its therapeutic uses. The present disclosure further provides ...  
WO/2019/155066A1
The present invention relates to oxadiazole derivatives (Ι') thereof that may be used as fungicides.  
WO/2019/149255A1
The present invention provides a compound represented by formula (I). The present invention also relates to a pharmaceutical composition containing the compound of formula (I) and use of the compound in the preparation of an indoleamine-...  
WO/2019/149159A1
Disclosed in the present invention are a composition comprising a compound represented by formula (I), a preparation method therefor, and use thereof in the field of diseases relating to IDO1.  
WO/2019/144859A1
Provided is a modulator of indoleamine 2,3-dioxygenase, a preparation method and a use thereof. Specifically, it relates to a compound of the Formula (I) and Formula (II), an isomer thereof, a pharmaceutically acceptable salt or a pharma...  
WO/2019/144041A1
Provided are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein A, Z, B, R1, R2, R3, G1, G2, and G3 are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of ...  
WO/2019/141740A1
The present invention related to compounds of Formula (I): or an agronomically acceptable salt thereof, wherein Q, X, Z, R2 and R3 are as described herein. The inventions further relates to compositions comprising said compounds, to meth...  
WO/2019/141027A1
The present invention provides a novel indoleamine 2,3-dioxygenase inhibitor, a preparation method thereof, and a pharmaceutical composition, in which the definitions of n, Y, Z, R1, R2, R3, and R4 are as stated in the specification. Als...  
WO/2019/142191A1
Novel compounds capable of inhibiting methionine metabolic pathway are provided. These compounds are used in inhibiting cystathionin y-synthase (CGS) in general, and in plants, fungi and bacteria, in particular. These compounds of the in...  
WO/2019/142192A1
Novel compounds capable of inhibiting methionine metabolic pathway are provided. These compounds are used in inhibiting cystathionin γ-synthase (CGS) in general, and in plants, fungi and bacteria, in particular. These compounds of the i...  
WO/2019/134993A1
The present invention relates to benzamide compounds of formula (I), the N-oxides and the salts thereof (I), where the variables are as defined in the claims and the description. The invention also relates to compositions comprising such...  
WO/2019/131867A1
The development of novel agricultural/horticultural fungicides is desired due to damage by diseases continuing to be a major issue, the evolution of diseases resistant to existing chemicals, and other such factors in crop production such...  
WO/2019/122347A1
The present invention relates to N-(1,2,5-oxadiazol-3-yl)-benzamide compounds of formula (I) wherein the variables are defined as in the claims and the description, the N-oxides and salts thereof and to compositions comprising the same. ...  
WO/2019/120237A1
Provided is a compound represented by formula (I). Also provided are a pharmaceutical composition containing the compound of formula (I) and use of the compound in preparing indoleamine-2,3-dioxygenase (IDO) inhibitor drugs. The compound...  
WO/2019/122345A1
The present invention relates to benzamide compounds of formula I wherein the variables are defined as in the claims and the description, the N-oxides and salts thereof,and to compositions comprising the same. The invention also relates ...  
WO/2019/115781A1
The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit t...  
WO/2019/106579A1
The present disclosure relates to novel crystalline forms of sulfonamide compounds, pharmaceutical compositions containing the crystalline form compounds and methods of preparing and using the same.  
WO/2019/101045A1
Disclosed in the present invention are a sphingosine-1-phosphate receptor modulator compound, a preparation method therefor and an application thereof. The present invention specifically provides a compound as represented by the followin...  
WO/2019/101709A1
Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulat...  
WO/2019/097054A1
Compounds of Formula (I), wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2019/094409A1
Disclosed are Ozanimod solid state forms, salts including hydrochloride and solid state thereof, processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.  
WO/2019/090082A1
Provided herein are compounds, compositions, and methods useful for the modulation of elF2B and the integrated stress response (ISR) signaling pathway and for treating related diseases, disorders and conditions.  
WO/2019/088311A1
The present invention relates to a compound having STAT3 inhibitory activity, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, and a pharmaceutical use thereof. The compound of the present invention efficiently inhibit...  
WO/2019/090069A1
Provided herein are compounds, compositions, and methods useful for the modulation of elF2B, for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.  
WO/2019/090074A1
Provided herein are compounds of formula (I) and (II), compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.  
WO/2019/090078A1
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.  
WO/2019/084463A1
The present disclosure is concerned with oxadiazole and thiadiazole analogs that are capable of inhibiting TGF-β and methods of treating cancers such as, for example, multiple myeloma and a hematologic malignancy, and methods of treatin...  
WO/2019/084450A1
This invention provides antibacterial and antiviral compositions and methods. The compositions possess prolonged and powerful antibacterial/antiviral functions under light exposure and even under completely dark conditions, while dayligh...  
WO/2019/076324A1
Disclosed are a salt of indoleamine-2,3-dioxygenase inhibitor and a preparation method therefor. In particular, disclosed are a salt of a compound of formula I and a variety of amorphous substances and polymorphs thereof, wherein the def...  
WO/2019/076904A1
The application relates to compounds of formula (I) that show great affinity and activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially the α2δ-1 subunit of voltage-gated calcium channels or dual activi...  
WO/2019/073399A1
The invention relates to crystalline forms of a 3-substituted 1,2,4-oxadiazole compound, methods of their preparation, and related pharmaceutical preparations thereof. The invention also relates to preparations suitable for pharmaceutica...  
WO/2019/067678A1
The invention relates to crystalline forms of a 3-substituted 1,2,4-oxadiazole compound, including an anhydrous crystalline form, methods of their preparation, and related pharmaceutical preparations thereof. The invention also relates t...  
WO/2019/058290A1
The present invention relates to an improved process for the preparation of optically chiral amino compound. The present invention particularly relates to the improved process for the preparation of (S)-1-amino-2,3-dihydro-1H-indene-4-ca...  
WO/2019/057104A1
The present invention relates to a salt of a dioxygenase inhibitor and a preparation method therefor and the use thereof, in particular relates to a salt of (Z)-N-(3-bromo-4-fluoro-phenyl)-4-((2-(N-(cyclopropylsulfony l)-S-methylsulfinyl...  
WO/2019/052932A1
The present invention relates to novel trifluoromethyloxadiazoles of the formula I as defined herein, or an N-oxide and/or their agriculturally useful salts and to their use for controlling phytopathogenic fungi; to a method for combatin...  
WO/2019/042219A1
The present invention relates to a crystalline form of ozanimod hydrochloride and a preparation method therefor. The crystalline form of ozanimod hydrochloride provided by the present invention can be used to treat autoimmune diseases, p...  
WO/2019/040724A1
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having an oxadiazole-oxadiazolone structure (e.g., oxadiazole-phenyl-oxadiazolone compounds, oxadiazole-pyridin...  
WO/2019/038042A1
The present invention relates to trifluoromethyloxadiazoles of the formula I, or the N-oxides, or the agriculturally useful salts thereof, and the use thereof for controlling phytopathogenic fungi; to a method for combating phytopathogen...  
WO/2019/040404A1
The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of bacterial infections in humans and other mammals. A new class of small molecules is disclosed that inhibits the ...  
WO/2019/025250A1
The present invention relates to trifluoromethyloxadiazoles of the formula I, or the N-oxides, or the agriculturally useful salts thereof, and the use thereof for controlling phytopathogenic fungi; to a method for combating phytopathogen...  
WO/2019/020451A1
The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles (compounds I), which can be obtained through reaction of hydroxyamidine compounds of formula II with trifluoroacetyl...  
WO/2019/020501A1
The present invention relates to a process for the preparation of 3-aryl-5-trifluoromethyl-1,2,4- oxadiazoles, which are useful as fungicidal compounds or as intermediates for the synthesis of fungicidal oxaciazole compounds, using trifl...  
WO/2019/022061A1
This fungicide for agricultural and horticultural use includes a compound represented by formula (I) (in the formula, X represents a halogen group, etc.; n represents any integer of 0-4; when n is 2 or higher, X may be the same or differ...  
WO/2019/011078A1
Provided is oxadiazole linkers and use thereof, more specifically to the compounds represented by formulas (I), (II), and (III), and their use in the preparation of antibody-drug conjugates (ADCs). The ADCs obtained from said oxadiazole ...  
WO/2019/013299A1
The present invention provides a thermally conductive material that has excellent thermal conductivity. The present invention also provides: a device that is provided with a thermally conductive layer that includes the thermally conducti...  
WO/2019/011170A1
Provided are: an oxadiazole derivative as shown in formula (1), or salts, esters, stereoisomers, tautomers, polymorphs, solvates, hydrates, metabolites or prodrugs thereof, or a mixture of said substances; a pharmaceutical composition co...  
WO/2019/010192A1
Disclosed are compounds of Formula 1, including all geometric and stereoisomers, tautomers, N-oxides, and salts thereof, wherein R1, Z1, W, Z2 and J are as defined in the disclosure. Also disclosed are compositions containing the compoun...  

Matches 1 - 50 out of 4,504