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Matches 1 - 50 out of 4,409

Document Document Title
WO/2019/025250A1
The present invention relates to trifluoromethyloxadiazoles of the formula I, or the N-oxides, or the agriculturally useful salts thereof, and the use thereof for controlling phytopathogenic fungi; to a method for combating phytopathogen...  
WO/2019/020451A1
The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles (compounds I), which can be obtained through reaction of hydroxyamidine compounds of formula II with trifluoroacetyl...  
WO/2019/020501A1
The present invention relates to a process for the preparation of 3-aryl-5-trifluoromethyl-1,2,4- oxadiazoles, which are useful as fungicidal compounds or as intermediates for the synthesis of fungicidal oxaciazole compounds, using trifl...  
WO/2019/022061A1
This fungicide for agricultural and horticultural use includes a compound represented by formula (I) (in the formula, X represents a halogen group, etc.; n represents any integer of 0-4; when n is 2 or higher, X may be the same or differ...  
WO/2019/011078A1
Provided is oxadiazole linkers and use thereof, more specifically to the compounds represented by formulas (I), (II), and (III), and their use in the preparation of antibody-drug conjugates (ADCs). The ADCs obtained from said oxadiazole ...  
WO/2019/013299A1
The present invention provides a thermally conductive material that has excellent thermal conductivity. The present invention also provides: a device that is provided with a thermally conductive layer that includes the thermally conducti...  
WO/2019/011170A1
Provided are: an oxadiazole derivative as shown in formula (1), or salts, esters, stereoisomers, tautomers, polymorphs, solvates, hydrates, metabolites or prodrugs thereof, or a mixture of said substances; a pharmaceutical composition co...  
WO/2019/010192A1
Disclosed are compounds of Formula 1, including all geometric and stereoisomers, tautomers, N-oxides, and salts thereof, wherein R1, Z1, W, Z2 and J are as defined in the disclosure. Also disclosed are compositions containing the compoun...  
WO/2019/007321A1
Disclosed in the present invention are an indoleamine-2,3-dioxygenase inhibitor compound, a preparation method therefor, and an application thereof. The indoleamine-2,3-dioxygenase inhibitor compound provided by the present invention is ...  
WO/2019/009412A1
The present invention addresses the problem of providing a novel compound having high LSD1 inhibitory activity, high selectivity for LSD1 inhibition, and/or having useful therapeutic effects for various diseases. One embodiment of the pr...  
WO/2019/001342A1
The present invention belongs to the field of medicine, and specifically discloses an amino alcohol derivative represented by Formula I, a pharmaceutically acceptable salt, solvate, polymorph or prodrug thereof. In addition, the present ...  
WO/2018/234139A1
2-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]aryloxy](thio)a cetamides for combating phytopathogenic fungi The present invention relates the compounds of the formula I and their N-oxides and agriculturally acceptable salts thereof, and t...  
WO/2018/227886A1
Provided in the present invention are a new type indoleamine 2,3-dioxygenase inhibitor and a preparation method and pharmaceutical composition thereof, wherein the definitions of the R and X groups are as shown in the description. Also p...  
WO/2018/230528A1
Provided are a novel nitrocatechol derivative having COMT inhibitory effect and DDC inhibitory effect or a salt thereof and a medicinal composition comprising the same. A compound represented by general formula (1) or a pharmaceutically ...  
WO/2018/230555A1
The present invention provides a compound represented by formula (1)( in formula (I), R1 represents a substituted or unsubstituted C1-6 alkyl group; R2 represents a substituted or unsubstituted C1-8 alkyl group; R3 represents a hydrogen ...  
WO/2018/224455A1
The invention relates to cyclopropyl compounds of formula (I), wherein the variables have the meanings as defined in the specification, to compositions comprising them, to active compound combinations comprising them, and to their use fo...  
WO/2018/219935A1
The invention relates to benzamides of formula (I), wherein Q is Q1 or Q2 or Q3 or Q4 (formulae (Q1), (Q2), (Q3), (Q4)); and their use as herbicides. In said formula (I), R2 is R2cR2dNC(O)NR2n-Z2, both R4 and R5 are hydrogen, R1, R3 and ...  
WO/2018/219936A1
The invention relates to benzamides of formula (I), wherein Q is Q1 or Q2 or Q3 or Q4, and their use as herbicides. In said formula (I), R2 is R2cR2dNC(O)NR2n-Z2, R5 is hydrogen, R1, R3, R4 and R6 represent groups such as hydrogen, halog...  
WO/2018/219797A1
The present invention relates to substituted oxadiazoles of the formula (I), or the N-oxides, or the agriculturally useful salts thereof, and to the use thereof for controlling phytopathogenic fungi; to a method for combating phytopathog...  
WO/2018/215818A1
The present invention relates to compounds of formula (I): wherein Q is O or S; R1 is a cyclic group substituted with at least one group X, wherein R1 may optionally be further substituted; X is any group comprising a carbonyl group; and...  
WO/2018/214958A1
Disclosed are a crystal form of an indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor and a preparation method therefor.  
WO/2018/215807A1
The present invetion relates a new process for the preparation of ozanimod of the formula and acid addition salts, via new intermediates and a new polimop form of ozanimod base.  
WO/2018/213537A1
A label for an antibody or protein is described that is both site-selective and unusually stable in vivo. The label has a general formula given by Formula (I) wherein R1 is a metal chelator, a fluorophore or a click-chemistry synthon.  
WO/2018/202491A1
Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi The present invention relates to trifluoromethyloxadiazolesof the formula I, or the N-oxides, or theagriculturally useful salts thereof, and the use thereof for c...  
WO/2018/202535A1
Substituted benzoyl amides and their use as herbicides. The invention relates to benzoyl amides of general formula (I) as herbicides. In formula (I) X, R and Ra represent radicals such as alkyl, cycloalkyl and halogen. Q is a five-member...  
WO/2018/202694A1
The present invention refers to compounds of the following formula (I) or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions containing them and to a process for the preparation of said compounds: Formula (I), whe...  
WO/2018/202428A1
Fungicidal mixture comprising substituted 3-phenyl-5-(trifluoromethyl)-1,2,4-oxadiazoles The present invention relates to fungicidal mixtures comprising at least one substituted 3- phenyl-5-(trifluoromethyl)-1,2,4-oxadiazoles (compounds ...  
WO/2018/196747A1
The present invention belongs to the field of medical technology. Particularly, the present invention relates to a compound shown in formula (I), a pharmaceutically acceptable salt thereof, and a stereoisomer of the same. X, Y, Z, R1, R2...  
WO/2018/196861A1
The present invention relates to the field of pharmaceuticals, and in particular to a guanidine derivative containing a furan structure and a composition thereof. The derivative and the composition thereof can be used for preparing pharm...  
WO/2018/196768A1
The present invention relates to the field of medical chemistry, and relates to a heterocyclic compound serving as a PD-L1 inhibitor. Specifically, the present invention relates to a compound represented by formula A, or an isomer, pharm...  
WO/2018/193297A1
The present invention provides compounds which are modulators of RORϒ and their use for the treatment of diseases or conditions mediated by RORϒ. Further, the present invention relates to processes of preparing such compounds, their ta...  
WO/2018/188962A1
The present invention relates to novel trifluoromethyloxadiazoles of the formula (I), or the N-oxides, or theagriculturally useful salts thereof; and to intermediates that are useful for their preparation; and to the use of compounds of ...  
WO/2018/189340A1
The present invention relates to novel benzohydroxamic compounds of formula (I) and (II) and pharmaceutically acceptable salts, isomers and prodrugs thereof, exhibiting a high selective inhibitory activity against histone deacetylase 6 (...  
WO/2018/185211A1
Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/185013A1
Compounds of the Formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/184585A1
The present invention provides a compound for inhibiting IDO, a manufacturing method and a use thereof. The compound has a general structural formula of (I), wherein (II) is selected from a cis-isomer, a trans-isomer, or a mixture of cis...  
WO/2018/184986A1
Compounds of the formula (I): wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/184982A1
Compounds of the formula (I): wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/184985A1
Compounds of the formula (I): wherein the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.  
WO/2018/184988A1
Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/184185A1
Disclosed is an ozanimod addition salt crystal, which is provided with one or more improved characteristics compared with a known ozanimod solid form. Also disclosed are a preparation method for the ozanimod addition salt crystal, a phar...  
WO/2018/184392A1
The present invention provides formula I and formula II IDO inhibitors and preparation methods therefor, wherein R1, R2, and X groups are as defined in the specification. The present invention also provides a pharmaceutical composition c...  
WO/2018/184987A1
Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/184984A1
Compounds of the formula (I): wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.  
WO/2018/184970A1
The present invention relates to novel trifluoromethyloxadiazoles of the formula (I), or the N-oxides, or the agriculturally useful salts thereof; and to their use for controlling phytopathogenic fungi; and to a method for combating phyt...  
WO/2018/186365A1
The present invention relates to a novel read-through inducing agent, and also relates to a compound represented by general formula (I) (symbols in the formula are as described in the specification) or a pharmaceutically accepted salt th...  
WO/2018/187553A1
Disclosed are compounds of Formula 1, including all geometric and stereoisomers, tautomers, N-oxides, and salts thereof, wherein R1, L and J are as defined in the disclosure. Also disclosed are compositions containing the compounds of Fo...  
WO/2018/178304A1
Inhibitors of ALCAT1 are described having the general formula: (I). These compounds offer a treatment for aging and age-related diseases.  
WO/2018/183097A1
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof. Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disor...  
WO/2018/177871A1
Disclosed are N-(1,3,4-oxadiazole-2-yl)aryl carboxamides of formula (I) or the salts (I) thereof as well as the use thereof as herbicides.  

Matches 1 - 50 out of 4,409