Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 151 - 200 out of 1,363

Document Document Title
WO2005016874A3
The invention describes crown ether chelators, including crown ethers having the formula (A) or (B); and aza-substituted and thia-substituted analogs thereof. These crown ethers may be substituted by a dye moiety, a chemically reactive g...  
WO/2005/103019A1
Compounds having therapeutic utility are of general formula (1) wherein R, is H, C 1-C6 alkyl optionally substituted with F or C3-C6 cycloalkyl or C2-C4 alkenyl; A is O, CH2 or S(O)n where n is 0-2; one of W, X, Y and Z is N, CH or CR3 a...  
WO/2005/103041A2
The invention is directed to compositions and methods useful for treating Central Nervous System (CNS) disorders. Furthermore, the invention provides compositions and methods of treating sleep disorders. More specifically, the invention ...  
WO2005055715A3
Certain noel N-(heteroarylalkyl)alkanediamine derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula I: wherein Ar, a, r, R, R, R, R, R, b, c, R, R, R, R, R<5>, d, e, U, V, X...  
WO/2005/090292A1
The invention relates to a compound having general formula (I), wherein: A is selected from among one or more X, Y and/or Z groups; X represents an optionally-substituted methylene group; Y represents a C2-alkenylene, optionally substitu...  
WO2005068445A3
The invention relates to compounds of formula (I) wherein Het, A1, A2, A3, A4, D, W, T, Q, Y, X1, X2, R1, R2, R3, R4, k and m are as defined hereinabove, and, where applicable, to possible E/Z isomers, mixtures of E/Z isomers and/or taut...  
WO/2005/087236A1
Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.  
WO/2005/082870A1
It is intended to provide an ABC transporter inhibitor whereby the multi-drug resistance against anticancer drugs caused by the amplification and expression of MDR1 gene, which is the most serious problem in chemotherapy for cancer, or t...  
WO/2005/068445A2
The invention relates to compounds of formula (I) wherein Het, A1, A2, A3, A4, D, W, T, Q, Y, X1, X2, R1, R2, R3, R4, k and m are as defined hereinabove, and, where applicable, to possible E/Z isomers, mixtures of E/Z isomers and/or taut...  
WO/2005/063277A1
The invention relates to cyclic depsipeptides, especially 18-membered cyclohexadepsipeptides of general formula (I) and the salts thereof, wherein R1 represents nitrobenzyl or R'R''N-benzyl - wherein R' and R'' independently represent hy...  
WO/2005/055715A2
Certain noel N-(heteroarylalkyl)alkanediamine derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula I: wherein Ar, a, r, R, Ra, Rb, Rc, Rd, b, c, Re, Rf, Rg, Rh, R5, d, e, U...  
WO2005035473A3
Ditopic molecules in the form of linear reaction templates are used to construct ladder-like hydrocarbons known as [n]-ladderanes (n = 3,5). The templates assemble and position reactant molecules in the solid state for [2+2] photodimeriz...  
WO2005028425A3
Amidines and derivatives thereof of formula (I) are described. The process for their preparation and pharmaceutical compositions thereof are also described. The amidines of the invention are useful in the inhibition of chemotaxis of neut...  
WO/2005/049585A1
The present invention relates to novel macrocyclic compounds of the formula (I) wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or...  
WO2005021490A3
The invention relates to N-sulfonyl-alpha-amino-acetic acid derivatives of the general formula (I): including the optical isomers thereof and mixtures of such isomers, wherein Ar1 and Ar2 independently of each other stand for an optional...  
WO2004091547A3
Compounds useful for treating cellular proliferative diseases and disorders by inhibiting the activity of KSP are disclosed.  
WO/2005/035473A2
Ditopic molecules in the form of linear reaction templates are used to construct ladder-like hydrocarbons known as [n]-ladderanes (n = 3,5). The templates assemble and position reactant molecules in the solid state for [2+2] photodimeriz...  
WO2004094449A8
The present invention relates to new compounds represented by Formula (I); wherein M represents a macrolide subunit of the substructure II, Formula (II); L represents the chain of the substructure III, Formula (III); D represents the ste...  
WO2004062625A3
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. ...  
WO/2005/028425A2
Amidines and derivatives thereof of formula (I) are described. The process for their preparation and pharmaceutical compositions thereof are also described. The amidines of the invention are useful in the inhibition of chemotaxis of neut...  
WO/2005/023772A1
The invention relates to malonamide derivatives of formula (I), wherein: R1 is one of the following groups (Formulae a), b), c), d)); R2 is lower alkyl, lower alkinyl, -(CH2)n-O-lower alkyl, -(CH2)n-S-lower alkyl, -(CH2)n-CN, -(CR'R')n-C...  
WO/2005/023788A1
A microorganism belonging to Beauveria sp. and being capable of producing FKI-1366 substance A and/or FKI-1366 substance B and/or FKI-1366 substance C (Beauveria sp. FKI-1366, FERM BP-08459) is cultured in a medium and thus the FKI-1366 ...  
WO/2005/021490A2
The invention relates to N-sulfonyl-&agr -amino-acetic acid derivatives of the general formula (I): including the optical isomers thereof and mixtures of such isomers, wherein Ar1 and Ar2 independently of each other stand for an optional...  
WO/2005/016874A2
The invention describes crown ether chelators, including crown ethers having the formula (A) or (B); and aza-substituted and thia-substituted analogs thereof. These crown ethers may be substituted by a dye moiety, a chemically reactive g...  
WO2004071345A3
The present invention relates to a novel device and method for the detection of lithium ions in a biological fluid. In a preferred embodiment, the present invention provides a novel compound and a optical sensor which incorporates said c...  
WO2003099762A8
The invention provides a method for preventing or reducing the effects of oxidative stress on a substrate. The method includes the step of treating the substrate with a compound of formula (I), or a pharmaceutically acceptable salt there...  
WO/2005/003106A1
The present invention relates to macrocyclic compounds of formula (I), wherein R1, is (C1-8)alkyl, (C1-4)alkoxy(C1-4)alkyl, hydroxy(C1-6)alkyl, (C1-4)alkylthio(C1-4)alkyl, (C1-6)alkenyl, (C3-­7)cycloalkyl, (C3-7)cycloalkyl(C1-4)alkyl, p...  
WO2004071345A8
The present invention relates to a novel device and method for the detection of lithium ions in a biological fluid. In a preferred embodiment, the present invention provides a novel compound and a optical sensor which incorporates said c...  
WO/2004/094387A1
Disclosed herein is an antioxidant that is an alkylated iminodibenzyl of the general formula: (I) wherein: R1, R2, R3, and R4 are independently selected from the group consisting of hydrogen, alkyl moieties, and alkenyl moieties; and R5,...  
WO/2004/094449A1
The present invention relates to new compounds represented by Formula (I); wherein M represents a macrolide subunit of the substructure II, Formula (II); L represents the chain of the substructure III, Formula (III); D represents the ste...  
WO/2004/091547A2
Compounds useful for treating cellular proliferative diseases and disorders by inhibiting the activity of KSP are disclosed.  
WO/2004/071345A2
The present invention relates to a novel device and method for the detection of lithium ions in a biological fluid. In a preferred embodiment, the present invention provides a novel compound and a optical sensor which incorporates said c...  
WO2003092374A3
It has now been found that certain novel heterocyclic derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): R Preferred are those compounds of formula (I) where R<2> and R3 taken toge...  
WO/2004/062625A2
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. ...  
WO/2004/050623A1
Methods of making substituted phenylalkynes of formula (I).  
WO/2004/018410A1
A novel agricultural chemical, especially an insecticide or acaricide; and a substituted benzanilide compound represented by the general formula (1): (1) G-7 G-13 G-71 [wherein G represents a ring represented by G-7, G-13, G-71, etc.; W1...  
WO/2003/103656A1
Drugs having inhibitory activity against NF-κB activation, containing as the active ingredient substances selected from the group consisting of compounds represented by the general formula (I), pharmacologically acceptable salts thereof...  
WO/2003/099762A1
The invention provides a method for preventing or reducing the effects of oxidative stress on a substrate. The method includes the step of treating the substrate with a compound of formula (I), or a pharmaceutically acceptable salt there...  
WO2002066048A8
The invention relates to the use of crystal modification (I) of a cyclic depsipeptide of formula (I) for producing medicaments, particularly for combating endoparasites.  
WO2003057649A3
An ammonium selective ionophore for use in ion selective electrodes. The electrodes can be used to measure ammonium chloride, for example, at different concentrations (curves 1-6 in Figure 1).  
WO/2003/092374A2
It has now been found that certain novel heterocyclic derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): R Preferred are those compounds of formula (I) where R2 and R3 taken togeth...  
WO/2003/077906A1
This invention relates to cyclic etheramine derivatives or salts thereof and also to medicaments comprising the derivatives or salts. These cyclic etheramine derivatives are each represented by the following formula (1): wherein Y?1¿ an...  
WO/2003/078410A1
This invention relates to cyclic etheramine derivatives or salts thereof and also to medicaments comprising the derivatives or salts. These cyclic etheramine derivatives are each represented by the following formula (1):wherein Y?1¿ and...  
WO/2003/074498A1
A compound represented by the formula (I) [wherein A represents the formula CY1Y2OCY3Y4, CY1Y2SOnCY3Y4, CY1Y2NRCY3Y4, CY1=NCY3Y4, or CY1Y2N=CY3 (wherein n is 0, 1, or 2, and Y1, Y2, Y3, and Y4 each independently represents hydrogen, alky...  
WO/2003/070254A1
This invention features a compound of the following formula (I): wherein T is a transportophore, L is a bond or linker, and C is an antibiotic therapeutic agent, the transportophore is covalently bonded to the antibiotic therapeutic agen...  
WO/2003/057649A2
An ammonium selective ionophore for use in ion selective electrodes. The electrodes can be used to measure ammonium chloride, for example, at different concentrations (curves 1-6 in Figure 1).  
WO/2003/056310A1
A fluorionophore for the fluorescent detection of potassium ions.  
WO/2003/051853A1
A process for the preparation of [1,4,5]−oxadiazepine derivatives by reaction of N,N'−diacyl−hydrazines with 2,2'−disubstituted diethyl ethers to form 4,5−diacyl−[1,4,5]−oxadiazepines and reaction of the latter compounds wi...  
WO/2003/050099A1
Substituted phenylalkynes of formula (l), compositions containing them, and methods of making and using them to treat histamine-mediated conditions.  
WO/2003/040083A1
The present invention pertains to a process for preparing a compound of Formula I that is enantiomerically enriched at the chiral hydroxylation center indicated by Formula (I) comprising contacting a compound of Formula (II) with an oxid...  

Matches 151 - 200 out of 1,363