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Matches 1 - 50 out of 19,698

Document Document Title
WO/2018/127207A1
Disclosed in the present invention are a new thiazole compound, particularly a compound represented by formula (I), a pharmaceutical composition thereof and applications thereof in the preparation of drugs for the treatment of diseases r...  
WO/2018/123586A1
Provided is a polymerizable compound having a use in the production of a polymer that allows the manufacture of an optical film or similar with good reverse wavelength dispersion on a long wavelength side. A polymerizable compound indica...  
WO/2018/122510A1
The invention relates to a method for synthetising functionalised cyclic dithiocarbamates of formula (I), in which the various substituents are as defined in the description, by reacting a compound of formula (II): G-(CH2)n-C*H(NHR1)-X-R...  
WO/2018/121610A1
Provided are a compound as shown in general formula I, a pharmaceutically acceptable salt, an isomer and a solvate thereof, or a compound obtained through the substitution of any atom in the compound of formula I with an isotope thereof,...  
WO/2018/123625A1
A purpose of the present invention is to provide a polymerizable compound that can be used in the production of an optical film or similar with good reverse wavelength dispersion. This polymerizable compound is indicated by formula (I). ...  
WO/2018/115421A1
The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).  
WO/2018/114786A1
The present invention relates to carboxylic acid aromatic amides compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds...  
WO/2018/114657A1
The present invention relates to compounds of the formula (I), in which the substituents are as defined in claim 1, which are suitable for use as nematicides.  
WO/2018/117166A1
The present invention addresses the problem of providing: a novel thiazole derivative or a pharmacologically acceptable salt thereof; a pharmaceutical composition which contains the thiazole derivative or a pharmacologically acceptable s...  
WO/2018/112136A1
The invention relates to c-Kit inhibitors useful in the treatment of cancers, and other -threonine kinase mediated diseases, having the Formula: (I) wherein A, L, R1, R2, R3, and n are described herein.  
WO/2018/108671A1
The present invention relates to the compounds of formula (I), and the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein the variables are defined according to the description. The com...  
WO/2018/107332A1
The invention belongs to the technical field of compound synthesis, and specifically discloses a class of chiral aromatic heteroamine derivative and a synthesis method and application thereof. The chiral aromatic heteroamine derivative h...  
WO/2018/104856A1
A process of obtaining a purified geometric isomer of an unsaturated macrocyclic compound is disclosed herein. The process is effected by contacting an ion exchange medium comprising silver ions with a mixture comprising at least one geo...  
WO/2018/106284A1
This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or condit...  
WO/2018/106643A1
The invention relates to heterocyclic compounds of formula (I) and (IV) or pharmaceutically acceptable salts thereof, useful as modulators of demyelinating diseases. The invention also provides pharmaceutically acceptable compositions co...  
WO/2018/102399A1
The present invention provides indane acetic acid and their derivatives and methods for the treating and/or preventing of cognitive disorders.  
WO/2018/102358A1
The present invention provides indane acetic acid and their derivatives and methods for the treating and/or preventing of cognitive disorders based on the ApoE4 genotype of human subjects.  
WO/2018/101207A1
The present invention addresses the problem of providing: a polymerizable liquid crystal composition that makes it possible to manufacture an optical film that has excellent light resistance; and an optically anisotropic membrane, an opt...  
WO/2018/100834A1
Provided is a composition that has excellent near-infrared ray absorption stability and is useful for an optical film. The composition includes at least two of the compounds represented by general formula 2 or general formula 5.  
WO/2018/102726A1
Described are luciferin analogues, methods for making the analogues, kits including the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.  
WO/2018/096938A1
This polymerizable compound is represented by expression (I) (in the expression, Ar represents an aromatic hydrocarbon ring group/aromatic heterocyclic group optionally having a substituent; D represents an organic group of 1-67 carbons ...  
WO/2018/097149A1
This sulfide compound production method involves a first step in which a sulfonic acid chloride of a specific structure is reacted with a saturated alcohol compound of a specific structure in the presence of a base to obtain a correspond...  
WO/2018/087126A1
The present invention relates to amido-substituted cyclohexane compounds of general formula (I), in which A, R4, R6, R7, R8, R9, R10 and R11 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful ...  
WO/2018/089902A1
The disclosure relates to diaminothiazole derivatives of formula (I) where the variables are as defined herein, pharmaceutical compositions containing such compounds, and methods for the use of such compounds and compositions for the tre...  
WO/2018/084694A1
The present Invention' relates to a method of preparing reduced grapheme oxide, Incorporation of the adduced graphene oxide into polysioprene latex to provide a polyisoprene latex graphene composite and elastomerk articles prepared using...  
WO/2018/081612A1
Substituted hydrazone compounds, methods of making such compounds and metal complexes thereof, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds and metal complexes to treat, preve...  
WO/2018/081276A1
Compounds of formula (I), which are useful as CSF-1R inhibitors, are provided. Also provided are pharmaceutical compositions and kits comprising said compounds, as well as methods and uses pertaining to said compounds.  
WO/2018/078392A1
The present invention provides novel polymorphic forms of dasatinib compound of the formula 1 as well as the process for the preparation thereof.  
WO/2018/081384A1
The present disclosure relates to compounds of formula I which inhibit NaV1.7, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods using and making such compounds and compositions. (I)  
WO/2018/077898A1
A compound according to formula (I) wherein L is CH2−O, CH2−S, CH2−CH2, or CH=CH; R1 and R2 are independently selected out of H, halogen, C1 to C3 alkyl, halogenated C1 to C3 alkyl, C1 to C3 alkyloxy, or halogenated C1 to C3 alkylo...  
WO/2018/071327A1
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...  
WO/2018/067764A1
This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containi...  
WO/2018/064119A1
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.  
WO/2018/064557A1
The present disclosure relates to substituted fused bi- or tri- heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., sickle cell a...  
WO/2018/053587A1
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.  
WO/2018/051252A2
An object of the present invention is to provide an amide compound or a salt thereof that controls a mite. The present invention provides an amide compound represented by Formula (1) : or a salt thereof, wherein R1 represents C1-6 alkyl ...  
WO/2018/053126A1
Provided herein are substituted imidazo[1,2-a]pyridines useful as inhibitors of BMP signaling. The invention further provides pharmaceutical compositions of the compounds of the invention. The invention also provides medical uses of subs...  
WO/2018/051278A3
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051278A4
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/051252A3
An object of the present invention is to provide an amide compound or a salt thereof that controls a mite. The present invention provides an amide compound represented by Formula (1) : or a salt thereof, wherein R1 represents C1-6 alkyl ...  
WO/2018/053353A1
The present invention provides compounds according to Formula (I) as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity pr...  
WO/2018/051278A2
The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates ...  
WO/2018/044963A1
The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical composit...  
WO/2018/043400A1
A compound represented by formula (I) or a salt thereof. In formula (I), each of R1 and R4 independently represents a hydrogen atom, an unsubstituted or substituted C1-6 alkyl group or the like; R2 represents a hydrogen atom, an unsubsti...  
WO/2018/044783A1
Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders...  
WO/2018/045149A1
Disclosed are compounds of Formula (I), Formula (II), Formula (III), and Formula (IV) or salts thereof, wherein R2 is -OH or -OP(O)(OH)2; and R1 is defined herein. Also disclosed are methods of using such compounds as selective agonists ...  
WO/2018/035296A1
Kinases can be engineered to utilize an ATP analog that is not readily utilized by wild-type kinases by introducing a mutation in the ATP-binding pocket. However, application of this method has been limited by the membrane impermeability...  
WO/2018/034216A1
Provided are a compound, a composition, a cured object, an optically anisotropic body, and a reflective film that have a high refractive index anisotropy Δn and excellent light resistant properties, and that exhibit liquid crystallinity...  
WO/2018/029150A1
The invention relates to compounds acting as agonists of G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40), and having formula (I). Said compounds are useful in the treatment of diseases or disorders modulated by GPR120 and/or GP...  
WO/2018/031707A1
Disclosed are acyl benzo[d]thiazol-2-amines having a structure according to formula (I): including enantiomers, diastereomers, hydrates, solvates, pharmaceutically acceptable salts, and complexes thereof. The compounds may be useful for ...  

Matches 1 - 50 out of 19,698