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Matches 1 - 50 out of 20,055

Document Document Title
WO/2019/171277A1
The present invention is directed to cycloalkenyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the GPR120 and / or GPR40 receptors. 5 More particularly, ...  
WO/2018/151861A8
Provided herein are methods for determining if a compound has potential efficacy for the treatment for a specific symptom domain of schizophrenia, such as for example, the treatment of a negative symptom of schizophrenia. In addition, pr...  
WO/2019/166270A1
The invention relates to an organic electronic device comprising at least one electron transport, electron injection or electron generation layer comprising a compound of Formula (I) wherein all positions which are not linked to a -(A)a-...  
WO/2019/166269A1
The present invention relates to an organic electronic device comprising, between an anode and a cathode, at least one layer selected from an electron injection layer, an electron transport layer or an electron generation layer, the laye...  
WO/2019/166206A1
The present invention relates to an organic material and to an electronic device comprising the organic material, particularly to an electroluminescent device, particularly to an organic light emitting diode (OLED), wherein the semicondu...  
WO/2019/070709A8
The present invention provides compounds, compositions and methods for treating and/or preventing a flavivirus infection by administering such compounds and compositions.  
WO/2019/165189A1
Disclosed are protein arginine methyltransferase 5 (PRMT5) degradation / disruption compounds including a PRMT5 ligand, a degradation / disruption tag and a linker, and methods for use of such compounds in the treatment of PRMT5-mediated...  
WO/2019/165073A1
The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the disclosure. The present disclosure further ...  
WO/2019/164788A1
The invention provides methods for treating cancer using an aryl dihydro-2H-benzo[b][1,4]oxazine sulfonamide compound having RORg agonist activity, such as (S)-3-(6-(3-(difluoromethoxy)-5-fluorophenyl)-4-((3-(trifluo romethyl)phenyl)sulf...  
WO/2019/160798A1
Accelerator solutions containing transition metal complexes based on organic ligands having one or more S-C-N, S-C-C-N, or S-C(=S)-S moieties are useful for accelerating the peroxide cure of resins such as unsaturated polyester resins.  
WO/2019/158607A1
The present invention relates to the use of iminooxothiazolidine derivatives for preventing or treating hair growth disorders. The iminooxothiazolidine derivatives may be formulated as compositions suitable for either the systemic admini...  
WO/2019/157020A1
In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of trea...  
WO/2019/153789A1
The present invention relates to the technical field of biological imaging, and disclosed thereby are a photo-activated aggregation-induced emission probe having in situ generation capabilities, a preparation thereof and an application t...  
WO/2019/155923A1
The present invention addresses the problem of providing a colored photosensitive resin composition capable of forming a color filter having a higher brightness than color filters formed from conventionally known colored photosensitive r...  
WO/2019/151263A1
Provided is a method capable of effectively producing a 1,1-disubstituted hydrazine compound that is a target product. In this method for producing a 1,1-disubstituted hydrazine compound represented by formula (II), a hydrazine compound ...  
WO/2019/145857A2
The present invention provides an improved process for preparing 5-chloro-2-[(3,4,4- trifluoro-3-buten-l-yl)thio]-thiazole comprising reacting 2-[(3,4,4-trifluoro-3-buten-l-yl) thio]-thiazole with N-chlorosuccinimide (NCS) in the presenc...  
WO/2019/144842A1
The present invention relates to a thiazole-5-formic acid derivative, a stereoisomer and a pharmaceutically acceptable salt thereof, the structure of the thiazole-5-formic acid derivative being represented by general formula (I). The com...  
WO/2019/144765A1
Provided in the present application are an aromatic heterocyclic substituted olefin compound, a preparation method for same, a pharmaceutical composition of same, and applications thereof. The aromatic heterocyclic substituted olefin com...  
WO/2019/142191A1
Novel compounds capable of inhibiting methionine metabolic pathway are provided. These compounds are used in inhibiting cystathionin y-synthase (CGS) in general, and in plants, fungi and bacteria, in particular. These compounds of the in...  
WO/2019/142192A1
Novel compounds capable of inhibiting methionine metabolic pathway are provided. These compounds are used in inhibiting cystathionin γ-synthase (CGS) in general, and in plants, fungi and bacteria, in particular. These compounds of the i...  
WO/2019/133445A1
The present disclosure provides compounds of formula (I) and pharmaceutically acceptable salts, solvates and salts of the solvates thereof, pharmaceutical compositions containing compounds of formula (I), as well as the use of compounds ...  
WO/2019/122418A1
The present disclosure relates to biguanide derivatives of formula (I) and their rearrangement products. The present disclosure also relates to the use of these compounds in a method for treating cancer, in particular melanoma.  
WO/2019/126568A1
Nifuroxazide analogs, and their pharmaceutically acceptable salts and derivatives are described. Methods and uses are also provided that include the administration of an effective amount of the nifuroxazide analogs, or their pharmaceutic...  
WO/2019/122265A1
The present application relates to compounds of formula (I') or formula (I), such as formula (Ia), and their pharmaceutical compositions/preparations. This application further relates to methods of treating or preventing neurodegenerativ...  
WO/2019/123196A1
The present invention disclosed fluoralkenyl compounds of general formula (I), wherein; R, R1, R2, R3, A and integers n, m and k are as defined in description. The present invention further discloses use of the compounds of general formu...  
WO/2019/123375A1
This invention, in at least some embodiments, relates to an inventive molecule, compositions comprising same, and methods of use therof for treatment of a neurological disorder.  
WO/2019/121143A1
The present invention relates to compounds of formula (I) wherein the variables have the meanings as defined in the specification, to compositions comprising them, to active compound combinations comprising them, and to their use for pro...  
WO/2019/123378A1
This invention, in at least some embodiments, relates to an inventive molecule, compositions comprising same, and methods of use therof for treatment of a neurological disorder.  
WO/2019/124154A1
Provided are: a polymerizable liquid-crystal compound suitable for producing positive-C-plate retarder films which have excellent heat resistance and reverse wavelength dispersion characteristics; a polymerizable liquid-crystal compositi...  
WO/2019/115781A1
The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit t...  
WO/2018/151861A9
Provided herein are methods for determining if a compound has potential efficacy for the treatment for a specific symptom domain of schizophrenia, such as for example, the treatment of a negative symptom of schizophrenia. In addition, pr...  
WO/2019/106146A1
Compounds of formula (I) and related aspects.  
WO/2019/106156A1
Compounds of formula (I): (I) and related aspects.  
WO/2019/105933A1
Compounds of the formula (I), (I) wherein the substituents are as defined in claim 1, useful as pesticides, and especially fungicides.  
WO/2019/094851A1
Disclosed are methods of treating ataxia by administering to a patient in need thereof a riluzole prodrug such as troriluzole. Pharmaceutical compositions and kits including the riluzole prodrugs are also disclosed.  
WO/2019/087548A1
Provided is a fluorine-containing ether compound which is capable of forming a lubricating layer that has excellent wear resistance even if the thickness thereof is thin, and which is suitable as a material for a lubricant for magnetic r...  
WO/2019/090076A1
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.  
WO/2019/080882A1
Disclosed are a compound as shown in formula (I), a pharmaceutical composition comprising the compound of formula (I), and the use of the compound and pharmaceutical composition in the preparation of an HDAC inhibitor drug. The compound ...  
WO/2019/081575A1
The present inventions concerns use of a specific methoxyacrylate compound to control mosquitoes, and vector control products comprising that methoxyacrylate compound, in particular the invention relates to a substrate, to a composition,...  
WO/2019/080842A1
Provided in the present invention is a compound of formula (I) or pharmaceutically acceptable salt, solvate or metabolite thereof, which can be used for treating and/or preventing ischemia-reperfusion injury and related diseases, acute r...  
WO/2018/064119A8
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.  
WO/2019/074007A1
A polymerizable liquid crystal compound which is represented by general formula (1). (In general formula (1), the symbols are as defined in the description.)  
WO/2019/068817A1
The present invention relates to novel antiviral compounds with specific stereoconfiguration, especially to specific novel enantiomers, to a process for their preparation and to their use as medicaments, in particular as antiviral medica...  
WO/2019/070093A1
The present disclosure provides a compound of general Formula (I) having c-abl kinase inhibitory activity or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound, and a method useful to treat or ...  
WO/2019/070709A1
The present invention provides compounds, compositions and methods for treating and/or preventing a flavivirus infection by administering such compounds and compositions.  
WO/2019/063710A1
The invention relates to resorcinol-based compounds of formula (I), to the salts, solvates, optical and/or geometrical isomers thereof, to the use thereof as active agents for depigmenting, lightening and/ or bleaching keratin materials,...  
WO/2019/064961A1
Provided are: a photosensitive resin composition having high tolerance for focus depth in the formation of a punched pattern; a resist film which is a solidified product of the photosensitive resin composition; a method for forming a pat...  
WO/2019/060147A1
The present disclosure encompasses crystalline polymorphs of Ponesimod, processes for preparation thereof, and pharmaceutical compositions thereof.  
WO/2019/055825A1
The current methods and compositions provide for therapeutic approaches to treating hepatocellular carcinoma (HCC) and other types of cancer including, for example, pancreatic and colon cancer. Accordingly, certain aspects of the disclos...  
WO/2019/054944A1
The present invention relates to compounds of general Formula (I), and/or tautomers, enantiomers, solvates, hydrates, and pharmaceutically acceptable salts thereof. The present invention also relates to compounds of Formula (I) for use i...  

Matches 1 - 50 out of 20,055