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Matches 701 - 750 out of 1,347

Document Document Title
JP2886341B2  
JP2887201B2  
JP2875834B2  
JP2873609B2  
JP2871811B2  
JP2867905B2  
JP2868623B2  
JP2863528B2  
JP2862980B2  
JP2860285B2  
JP2860300B2  
JPH11501327A
(57) The salt permitted as the compound of the formula I in which the knowledge of the useful thing was carried out to the medical treatment of summary neurodegenerative disorder, gastroenteric motility disturbance, a nitric-oxide-syntha...  
JPH11500102A
(57) Summary book invention relates to those use in prevention and medical treatment of associated diseases like the new low 脂血症性 compound of formula (I), its manufacturing process and new intermediate field, the medicine composi...  
JPH10511937A
(57) The compounds in which summary book invention is shown by formula:, those production methods, polymer containing them, コポリマー, or a block co-polymer, Or it is related with those use in manufacture of those use and the adhes...  
JP2818692B2  
JP2818082B2
PURPOSE: To provide a new compound having a calcium-antagonizing action and useful for treating and preventing transient ischemic diseases, essential hypertension, etc. CONSTITUTION: A compound of formula I [X is >N-A-R1, >C(R1)R2; A is ...  
JPH10279568A
To obtain a new compound capable of reducing the concentration of an (ultra) low density lipoprotein cholesterol in plasma or serum and useful for treating and preventing hyperlipemia such as atherosclerosis. This compound is represented...  
JPH10279572A
To prepare a desired enantiomer of the subject compound in a high yield and/or a high diastereomeric ratio by bringing a specific aldehyde into contact with a specified optically active acetyl compound in the presence of a base. An aldeh...  
JP2808629B2  
JPH10509150A
(57) The salt permissible as the hetero ring compound by which knowledge was carried out to it being useful under the medical treatment of summary nitric oxide シンターゼ mediation illness and a disease, and medicine is indicated on...  
JP2793674B2  
JPH10508826A
(57) It is related with the new アルキル amino derivative denoted by summary type (I) :. Since these compounds have high selectivity and affinity over sigma 2 receptor, they are useful for the medical treatment of the disease of othe...  
JPH10506100A
(57) Compound of summary type (I) (R and R are OH, OOC*R, or O*R independently among a formula, and R is un-replacing or replaced C*C アルキル, アルケニル, アルキニル, or a phenyl group). This compound is useful as the incr...  
JPH10505350A
(57) Protection of a summary cardiac muscle is attained by medicating a patient with an effective amount of ベンゾチアゼピン derivatives. Although the ベンゾチアゼピン derivative has general formula (I), R expresses hydro...  
JP2751287B2  
JPH10504807A
(57) --: the compound shown by formula (I) which is the prevention medicine of a summary vitronectin receptor is indicated to be -- here, X*X', NR*CH, NC (O) R*CH, N=C, CR=C, CHR*CH, Are O*CH or S*CH, ;R is H, C アルキル, or Ben Jill...  
JPH10120667A
To obtain the subject aggregate enabling to charge a large amount of a substrate at once, efficiently produce an intermediate for synthesizing medicine compounds, and improved in water solubility without using a dissolution auxiliary by ...  
JPH10504825A
(57) Summary book invention relates to the directions for the salt permitted on the compound of formula (I) effective for checking crystal board condensation and bone resorption, or its medicine, the medicine composites which have this a...  
JPH10114741A
To obtain a guanidine intermediate useful for the production of a thrombin inhibitor by reacting a protected guanidylpyrazole with a heterocyclic compound in the presence of a basic catalyst. This method for producing a guanidine interme...  
JPH10504035A
(57) [Abstract] The present invention relates to those use in prevention and medical treatment of the medicine constituent containing the new intermediate for the new Blood lipid reduction compounds of formula (I), those manufacturing pr...  
JPH1081676A
To obtain the subject compound useful as e.g. an intermediate for synthesizing medicines such as calcium channel blockers in an industrially advantageous way by reaction of an aldehyde compound with a silyl keteneacetal compound in the p...  
JP2728564B2  
JPH1059951A
To obtain a new compound having action enhancing action of a retinoid such as retinoic acid and useful for a medicinal composition. This retinoid action enhancing compound is represented by formula I (R1 is H or 1-6C alkyl; R2 and R3 are...  
JPH1059953A
To obtain the subject compound having cholesterol synthesis-inhibiting action and useful for providing a medicinal composition for treating hypercholesterolemia, hypertriglyceridemia, atherosclerosis, etc. This squalene synthetase inhibi...  
JPH1045706A
To obtain a new diformyldiphenyldisulfide compound useful as a medicine, an agrochemical agent, a functional material and a synthetic intermediate of 2,3,4,5-tetrahydro-1,4-benzothiazepine useful as a medicine, an agrochmical agent and a...  
JP2714315B2
PURPOSE: To provide a new compound important as an intermediate for various pharmaceutical compounds such as diltiazem hydrochloride useful as a coronary vasodilator. CONSTITUTION: The epoxypropionic acid derivative of formula (ring A is...  
JP2712143B2  
JP2712144B2  
JPH1036268A
To obtain the subject preparation capable of completely controlling the release of active ingredients and continuously releasing sodium tianeptine by combining a polymer originating from cellulose and a calcium salt. This preparation is ...  
JPH1028596A
To obtain the subject compound as a medicine raw material, etc., in good yield by reacting a specific racemic type trans-3-(substituted) phenylglycidic acid ester with an amine, etc., in the presence of an asymmetric amidated enzyme and ...  
JP2703564B2  
JPH10500702A
(57) Summary type (A) (among a formula, X are オキシ, チオ, and *S (O) * or *S (O) *, and;Y) it is carbonyl or methylene, ;R, R, R, and R are hydrogen or a substituent, and;R is アルキル or cycloalkyl methyl --; and Z -- an acid...  
JPH107667A
To obtain the subject compound in a short time in a high yield by intramolecular cyclization of a specific propionic acid derivative in the presence of an α-chlorocarboxylic acid. This compound, a 1,5-benzothiazepine derivative (salt) o...  
JP2693248B2  
JPH09328420A
To obtain a calcium receptor-active composition effective against primary and secondary hyperparathyroidism, Behcet disease, maligant hypercalcemia, osteoporosis, etc., by using a specific amine derivative as an active ingredient. This c...  
JPH09299099A
To produce the subject compound useful for production, etc., of optically active 1,5-benzothiazepin derivatives by reacting a compound of racemic type trans-3-phenylglycidamides with microorganisms capable of hydrolyzing either of optica...  
JP2676720B2  
JP2674232B2  
JPH09286773A
To obtain 1,5-benzodiazepine derivative, useful as an intermediate for a pharmaceutical compound for angina pectoris, etc., by using a specific new compound as a raw material. This 1,5-benzodiazepine derivative of formula II [ring A and ...  
JPH09281109A
To provide a screening method of a calcium receptor activation compound. The method for screening a compound which can produce an effect on the activity of a calcium receptor, by using a recombinant cell making a functional calcium recep...  

Matches 701 - 750 out of 1,347